Patents Assigned to Kineta, Inc.
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Patent number: 11958873Abstract: The present invention is directed to compounds having the Formula (I), (II), (III), (IV), and (V), compositions thereof, and methods for the treatment of a condition associated with a dysfunction in proteostasis.Type: GrantFiled: December 17, 2021Date of Patent: April 16, 2024Assignee: Kineta, Inc.Inventors: Matthew Cullen, Sheila Hauck, Bolin Geng, Megan Foley, Cecilia M. Bastos, Benito Munoz, Markus Haeberlein, Bradley Tait
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Publication number: 20200270274Abstract: Disclosed herein are compounds, pharmaceutical compositions, and related methods for the treatment of viral infection, including RNA viral infection in subjects. The compounds, pharmaceutical compositions, and methods can modulate the innate immune antiviral response in vertebrate cells, including activating the RIG-I pathway.Type: ApplicationFiled: May 8, 2020Publication date: August 27, 2020Applicant: Kineta, Inc.Inventors: Shawn P. Iadonato, Kristin M. Bedard, Kerry W. Fowler, Ikenna Madu, Shari Kaiser
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Publication number: 20190002477Abstract: Disclosed herein are compounds, pharmaceutical compositions, and related methods for the treatment of viral infection, including RNA viral infection in subjects. The compounds, pharmaceutical compositions, and methods can modulate the innate immune antiviral response in vertebrate cells, including activating the RIG-I pathway.Type: ApplicationFiled: January 31, 2018Publication date: January 3, 2019Applicant: Kineta, Inc.Inventors: Shawn P. Iadonato, Kristin M. Bedard, Kerry W. Fowler, Ikenna Madu, Shari Kaiser
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Patent number: 9956285Abstract: Disclosed herein are compounds and related compositions for the treatment of viral infection, including RNA viral infection, and compounds that can modulate the RIG-I pathway in vertebrate cells, including compounds that can activate the RIG-I pathway.Type: GrantFiled: January 30, 2017Date of Patent: May 1, 2018Assignee: Kineta, Inc.Inventors: Shawn P. Iadonato, Kristin M. Bedard, Myra Wang Imanaka, Kerry W. Fowler
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Patent number: 9884876Abstract: Disclosed herein are compounds, pharmaceutical compositions, and related methods for the treatment of viral infection, including RNA viral infection in subjects. The compounds, pharmaceutical compositions, and methods can modulate the innate immune antiviral response in vertebrate cells, including activating the RIG-I pathway.Type: GrantFiled: May 8, 2015Date of Patent: February 6, 2018Assignee: Kineta, Inc.Inventors: Shawn P. Iadonato, Kristin M. Bedard, Kerry W. Fowler, Ikenna Madu, Shari Kaiser
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Publication number: 20170258897Abstract: Disclosed herein are compounds and related compositions for the treatment of viral infection, including RNA viral infection, and compounds that can modulate the RIG-I pathway in vertebrate cells, including compounds that can activate the RIG-I pathway.Type: ApplicationFiled: January 30, 2017Publication date: September 14, 2017Applicant: Kineta, Inc.Inventors: Shawn P. Iadonato, Kristin M. Bedard, Myra Wang Imanaka, Kerry W. Fowler
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Publication number: 20170057978Abstract: Disclosed herein are compounds, pharmaceutical compositions, and related methods for the treatment of viral infection, including RNA viral infection in subjects. The compounds, pharmaceutical compositions, and methods can modulate the innate immune antiviral response in vertebrate cells, including activating the RIG-I pathway.Type: ApplicationFiled: May 8, 2015Publication date: March 2, 2017Applicant: Kineta, Inc.Inventors: Shawn P. Iadonato, Kristin M. Bedard, Kerry W. Fowler, Ikenna Madu, Shari Kaiser
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Patent number: 9555106Abstract: Disclosed herein are compounds and related compositions for the treatment of viral infection, including RNA viral infection, and compounds that can modulate the RIG-I pathway in vertebrate cells, including compounds that can activate the RIG-I pathway.Type: GrantFiled: September 27, 2012Date of Patent: January 31, 2017Assignee: Kineta, Inc.Inventors: Shawn P. Iadonato, Kristin Bedard, Myra Wang Imanaka, Kerry W. Fowler
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Patent number: 9458492Abstract: Disclosed herein are methods for identifying compounds for the treatment of viral infection, including RNA viral infection and uses of the compounds as pharmaceutical compositions. The identified compounds modulate the RIG-I pathway in vertebrate cells.Type: GrantFiled: February 23, 2012Date of Patent: October 4, 2016Assignee: Kineta, Inc.Inventors: Shawn P Iadonato, Kristin Bedard
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Patent number: 9408826Abstract: Disclosed herein are compounds and related compositions for the treatment of viral infection, including RNA viral infection, and compounds that can modulate the RIG-I pathway in vertebrate cells, including compounds that can activate the RIG-I pathway.Type: GrantFiled: April 21, 2011Date of Patent: August 9, 2016Assignee: Kineta, Inc.Inventors: Shawn P. Iadonato, Kristin Bedard
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Patent number: 9301952Abstract: Disclosed herein are compounds and related compositions for the treatment of viral infection, including RNA viral infection, and compounds that can modulate the RIG-I pathway in vertebrate cells, including compounds that can activate the RIG-I pathway.Type: GrantFiled: April 20, 2011Date of Patent: April 5, 2016Assignee: Kineta, Inc.Inventors: Shawn P. Iadonato, Kristin Bedard
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Patent number: 9115065Abstract: Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain novel semicarbazides, sulfonyl carbazides, ureas and related compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by hemorrhagic fever viruses is disclosed, i.e., including but not limited to Arenaviridae (Junin, Machupo, Guanavito, Sabia and Lassa), Filoviridae (ebola and Marburg viruses), Flaviviridae (yellow fever, omsk hemorrhagic fever and Kyasanur Forest disease viruses), and Bunyaviridae (Rift Valley fever).Type: GrantFiled: February 26, 2013Date of Patent: August 25, 2015Assignee: Kineta, Inc.Inventors: Dongcheng Dai, Tove Bolken, Sean M. Amberg, Dennis E. Hruby, Thomas R. Bailey
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Patent number: 9073946Abstract: Disclosed herein are compounds and related compositions for the treatment of viral infection, including RNA viral infection, and compounds that can modulate the RIG-I pathway in vertebrate cells, including compounds that can activate the RIG-I pathway.Type: GrantFiled: February 12, 2013Date of Patent: July 7, 2015Assignee: Kineta, Inc.Inventors: Shawn P. Iadonato, Kristin M. Bedard, Ernesto J. Muñoz, Myra W. Imanaka, Kerry W. Fowler
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Patent number: 8927561Abstract: Disclosed herein are compounds and related compositions for the treatment of viral infection, including RNA viral infection, and compounds that can modulate the RIG-I pathway in vertebrate cells, including compounds that can activate the RIG-I pathway.Type: GrantFiled: April 20, 2011Date of Patent: January 6, 2015Assignee: Kineta, Inc.Inventors: Shawn P. Iadonato, Kristin Bedard
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Patent number: 8895608Abstract: Disclosed herein are compounds and related compositions for the treatment of viral infection, including RNA viral infection, and compounds that can modulate the RIG-I pathway in vertebrate cells, including compounds that can activate the RIG-I pathway.Type: GrantFiled: April 20, 2011Date of Patent: November 25, 2014Assignee: Kineta, Inc.Inventors: Shawn P. Iadonato, Kristin Bedard
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Patent number: 8871799Abstract: Disclosed herein are compounds and related compositions for the treatment of viral infection, including RNA viral infection, and compounds that can modulate the RIG-I pathway in vertebrate cells, including compounds that can activate the RIG-I pathway.Type: GrantFiled: April 20, 2011Date of Patent: October 28, 2014Assignee: Kineta, Inc.Inventors: Shawn P. Iadonato, Kristin Bedard
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Publication number: 20140227321Abstract: Disclosed herein are compounds and related compositions for the treatment of viral infection, including RNA viral infection, and compounds that can modulate the RIG-I pathway in vertebrate cells, including compounds that can activate the RIG-I pathway.Type: ApplicationFiled: September 27, 2012Publication date: August 14, 2014Applicant: Kineta, Inc.Inventors: Shawn P. Iadonato, Kristin Bedard, Myra Wang Imanaka, Kerry W. Fowler
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Publication number: 20140199348Abstract: Disclosed herein are compounds and related compositions for the treatment of viral infection, including RNA viral infection, and compounds that can modulate the RIG-I pathway in vertebrate cells, including compounds that can activate the RIG-I pathway.Type: ApplicationFiled: February 12, 2013Publication date: July 17, 2014Applicant: KINETA, INC.Inventors: Shawn P. Iadonato, Kristin M. Bedard, Ernesto J. Muñoz, Myra W. Imanaka, Kerry W. Fowler
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Publication number: 20130045229Abstract: Disclosed herein are compounds and related compositions for the treatment of viral infection, including RNA viral infection, and compounds that can modulate the RIG-I pathway in vertebrate cells, including compounds that can activate the RIG-I pathway.Type: ApplicationFiled: April 20, 2011Publication date: February 21, 2013Applicant: KINETA, INC.Inventors: Shawn P. Iadonato, Kristin Bedard
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Publication number: 20130039945Abstract: Disclosed herein are compounds and related compositions for the treatment of viral infection, including RNA viral infection, and compounds that can modulate the RIG-I pathway in vertebrate cells, including compounds that can activate the RIG-I pathway.Type: ApplicationFiled: April 20, 2011Publication date: February 14, 2013Applicant: Kineta, Inc.Inventors: Shawn P. Iadonato, Kristin Bedard