Patents by Inventor Alexander Shakhov

Alexander Shakhov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods of protecting against apoptosis using lipopeptides
    Patent number: 9381225
    Abstract: The use of lipopeptides comprising variable groups defined as H or optionally substituted C6-C20 aliphatic and a peptide of one of the following amino acid sequences: GEESN (SEQ ID NO: 17), QGEESNDK (SEQ ID NO: 20), and VQGEESNDK (SEQ ID NO: 21). The use of the lipopeptides for activating Toll-like receptors (TLRs) in cells is described.
    Type: Grant
    Filed: March 6, 2015
    Date of Patent: July 5, 2016
    Assignees: CLEVELAND CLINIC FOUNDATION, CLEVELAND BIOLABS, INC.
    Inventors: Alexander Shakhov, Andrei Gudkov, Elena Feinstein
  • METHODS OF PROTECTING AGAINST APOPTOSIS USING LIPOPEPTIDES
    Publication number: 20150306168
    Abstract: The use of lipopeptides as inducers of NF-?B for the protection of mammals from the effects of apoptosis is described.
    Type: Application
    Filed: March 6, 2015
    Publication date: October 29, 2015
    Inventors: Alexander Shakhov, Andrei Gudkov
  • METHODS FOR INCREASING AND MOBILIZING HEMATOPOIETIC STEM CELLS
    Publication number: 20150174195
    Abstract: A method is provided for increasing the number of hematopoietic stem cells in the bone marrow, increasing the mobilization of these cells to migrate from the bone marrow to the bloodstream and elsewhere, and increasing the number of differentiating hematopoietic stem cells in the bloodstream.
    Type: Application
    Filed: March 4, 2015
    Publication date: June 25, 2015
    Inventors: Alexander Shakhov, Evguenia Strom
  • Methods of protecting against apoptosis using lipopeptides
    Patent number: 9006183
    Abstract: The use of lipopeptides as inducers of NF-?B for the protection of mammals from the effects of apoptosis is described.
    Type: Grant
    Filed: July 15, 2013
    Date of Patent: April 14, 2015
    Assignees: Cleveland Clinic Foundation, Cleveland BioLabs, Inc.
    Inventors: Alexander Shakhov, Andrei Gudkov
  • METHODS FOR INCREASING AND MOBILIZING HEMATOPOIETIC STEM CELLS
    Publication number: 20140045747
    Abstract: A method is provided for increasing the number of hematopoietic stem cells in the bone marrow, increasing the mobilization of these cells to migrate from the bone marrow to the bloodstream and elsewhere, and increasing the number of differentiating hematopoietic stem cells in the bloodstream.
    Type: Application
    Filed: July 2, 2013
    Publication date: February 13, 2014
    Applicant: Cleveland Biolabs, Inc.
    Inventors: Alexander Shakhov, Evguenia Strom
  • METHODS OF PROTECTING AGAINST APOPTOSIS USING LIPOPEPTIDES
    Publication number: 20140045750
    Abstract: The use of lipopeptides as inducers of NF-?B for the protection of mammals from the effects of apoptosis is described.
    Type: Application
    Filed: July 15, 2013
    Publication date: February 13, 2014
    Inventors: Alexander Shakhov, Andrei Gudkov
  • Methods of protecting against apoptosis using lipopeptides
    Patent number: 8524668
    Abstract: The use of lipopeptides as inducers of NF-?B for the protection of mammals from the effects of apoptosis is described.
    Type: Grant
    Filed: March 18, 2011
    Date of Patent: September 3, 2013
    Assignees: Cleveland Clinic Foundation, Cleveland Biolabs, Inc.
    Inventors: Alexander Shakhov, Andrei Gudkov
  • METHODS OF PROTECTING AGAINST APOPTOSIS USING LIPOPEPTIDES
    Publication number: 20110237507
    Abstract: The use of lipopeptides as inducers of NF-?B for the protection of mammals from the effects of apoptosis is described.
    Type: Application
    Filed: March 18, 2011
    Publication date: September 29, 2011
    Applicants: CLEVELAND CLINIC FOUNDATION, CLEVELAND BIOLABS, INC.
    Inventors: Alexander Shakhov, Andrei Gudkov
  • Methods of protecting against apoptosis using lipopeptides
    Patent number: 8008260
    Abstract: The use of lipopeptides as inducers of NF-?B for the protection of mammals from the effects of apoptosis is described.
    Type: Grant
    Filed: June 13, 2006
    Date of Patent: August 30, 2011
    Assignees: Cleveland Clinic Foundation, Cleveland Biolabs, Inc.
    Inventors: Alexander Shakhov, Andrei Gudkov
  • METHODS FOR INCREASING AND MOBILIZING HEMATOPOIETIC STEM CELLS
    Publication number: 20100055077
    Abstract: A method is provided for increasing the number of hematopoietic stem cells in the bone marrow, increasing the mobilization of these cells to migrate from the bone marrow to the bloodstream and elsewhere, and increasing the number of differentiating hematopoietic stem cells in the bloodstream.
    Type: Application
    Filed: January 9, 2008
    Publication date: March 4, 2010
    Inventors: Alexander Shakhov, Evguenia Strom