Patents by Inventor Andrew Pollard

Andrew Pollard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9567630
    Abstract: This disclosure provides a biochip comprising a plurality of wells. The biochip includes a membrane that is disposed in or adjacent to an individual well of the plurality of wells. The membrane comprises a nanopore, and the individual well comprises an electrode that detects a signal upon ionic flow through the pore in response to a species passing through or adjacent to the nanopore. The electrode can be a non-sacrificial electrode. A lipid bilayer can be formed over the plurality of wells using a bubble.
    Type: Grant
    Filed: October 22, 2014
    Date of Patent: February 14, 2017
    Assignee: Genia Technologies, Inc.
    Inventors: Randall W. Davis, Edward Shian Liu, Eric Takeshi Harada, Anne Aguirre, Andrew Trans, James Pollard, Cynthia Cech
  • Publication number: 20160333104
    Abstract: The disclosure provides TNF-like ligand 1a (TL1a)-binding proteins comprising an antigen binding domain of an antibody which binds specifically to TL1a and inhibits interaction of TL1a and Death Receptor 3 (DR3) and which does not inhibit the interaction of TL1a and Decoy Receptor 3 (DcR3). The disclosure also provides uses of the TL1a-binding proteins.
    Type: Application
    Filed: July 11, 2016
    Publication date: November 17, 2016
    Inventors: Lynn Dorothy Poulton, Adam Clarke, Andrew James Pow, Debra Tamvakis, George Kopsidas, Anthony Gerard Doyle, Philip Anthony Jennings, Matthew Pollard
  • Publication number: 20160327507
    Abstract: A biochip for molecular detection and sensing is disclosed. The biochip includes a substrate. The biochip includes a plurality of discrete sites formed on the substrate having a density of greater than five hundred wells per square millimeter. Each discrete site includes sidewalls disposed on the substrate to form a well. Each discrete site includes an electrode disposed at the bottom of the well. In some embodiments, the wells are formed such that cross-talk between the wells is reduced. In some embodiments, the electrodes disposed at the bottom of the wells are organized into groups of electrodes, wherein each group of electrodes shares a common counter electrode. In some embodiments, the electrode disposed at the bottom of the well has a dedicated counter electrode. In some embodiments, surfaces of the sidewalls are silanized such that the surfaces facilitate the forming of a membrane in or adjacent to the well.
    Type: Application
    Filed: March 10, 2016
    Publication date: November 10, 2016
    Inventors: Randall W. DAVIS, Edward Shian LIU, Eric Takeshi HARADA, Anne AGUIRRE, Andrew TRANS, James POLLARD, Cynthia CECH, Hui TIAN, Robert YUAN, John FOSTER, Roger CHEN
  • Patent number: 9322062
    Abstract: A biochip for molecular detection and sensing is disclosed. The biochip includes a substrate. The biochip includes a plurality of discrete sites formed on the substrate having a density of greater than five hundred wells per square millimeter. Each discrete site includes sidewalls disposed on the substrate to form a well. Each discrete site includes an electrode disposed at the bottom of the well. In some embodiments, the wells are formed such that cross-talk between the wells is reduced. In some embodiments, the electrodes disposed at the bottom of the wells are organized into groups of electrodes, wherein each group of electrodes shares a common counter electrode. In some embodiments, the electrode disposed at the bottom of the well has a dedicated counter electrode. In some embodiments, surfaces of the sidewalls are silanized such that the surfaces facilitate the forming of a membrane in or adjacent to the well.
    Type: Grant
    Filed: October 22, 2014
    Date of Patent: April 26, 2016
    Inventors: Randall W. Davis, Edward Shian Liu, Eric Takeshi Harada, Anne Aguirre, Andrew Trans, James Pollard, Cynthia Cech, Hui Tian, Robert Yuan, John Foster, Roger Chen
  • Publication number: 20140183791
    Abstract: Described is a substantially spherical biomass pellet, comprising compressed particulate biomass including one or more of ligno-cellulosic material, recycling waste, and dewatered municipal solid waste, useful as a fuel. Also described are methods for producing such pellets using one or more of untorrefied biomass and torrefied biomass, and apparatus for producing such biomass pellets.
    Type: Application
    Filed: February 9, 2012
    Publication date: July 3, 2014
    Applicant: Queen's University at Kingston
    Inventors: William Andrew Duncan, Andrew Pollard, M. Hachimi Fellouah
  • Publication number: 20130089571
    Abstract: The present invention relates to compositions comprising at least one purified PorA protein antigen and at least one purified FetA protein antigen. In particular, said PorA/FetA antigens are antigenically variable antigens comprising the variable regions of PorA/FetA. Specific combinations of PorA/FetA epitopes are presented for example in Table 3. The invention also relates to methods of immunisation comprising administering said compositions, and to methods for producing compositions. Preferably the compositions are purified protein compositions. Preferably the compositions are vaccine compositions.
    Type: Application
    Filed: October 24, 2012
    Publication date: April 11, 2013
    Inventors: Martin Maiden, Ian Feavers, Andrew Pollard
  • Patent number: 8318179
    Abstract: The present invention relates to compositions comprising at least one purified PorA protein antigen and at least one purified FetA protein antigen. In particular, said PorA/FetA antigens are antigenically variable antigens comprising the variable regions of PorA/FetA. Specific combinations of PorA/FetA epitopes are presented for example in Table 3. The invention also relates to methods of immunization comprising administering said compositions, and to methods for producing compositions. Preferably the compositions are purified protein compositions. Preferably the compositions are vaccine compositions.
    Type: Grant
    Filed: June 3, 2005
    Date of Patent: November 27, 2012
    Assignee: ISIS Innovation, Ltd.
    Inventors: Martin Maiden, Ian Feavers, Andrew Pollard
  • Publication number: 20100183676
    Abstract: The present invention relates to a composition comprising at least one purified Opa HV 1 protein epitope and at least one purified Opa HV2 protein epitope. The epitopes are preferably purified protein epitopes, preferably recombinant epitopes. The composition is preferably a pharmaceutical composition, more preferably a vaccine composition. The invention also relates to methods of immunisation and to specific formulations presented in the tables, and to novel nucleic acids encoding Opa alleles.
    Type: Application
    Filed: December 22, 2005
    Publication date: July 22, 2010
    Applicant: ISIS INNOVATION LTD.
    Inventors: Martin Maiden, Ian Feavers, Andrew Pollard
  • Publication number: 20090209857
    Abstract: A method and system for quantifying particles in a flow system are provided.
    Type: Application
    Filed: November 6, 2008
    Publication date: August 20, 2009
    Inventors: Frank Secretain, Andrew Pollard, Christopher G. Ball, A.K. Mesbah Uddin, Mohamed Ali, Brian Milne, G. Andrew Y. Hamilton
  • Publication number: 20070224222
    Abstract: The present invention relates to compositions comprising at least one purified PorA protein antigen and at least one purified FetA protein antigen. In particular, said PorA/FetA antigens are antigenically variable antigens comprising the variable regions of PorA/FetA. Specific combinations of PorA/FetA epitopes are presented for example in Table 3. The invention also relates to methods of immunisation comprising administering said compositions, and to methods for producing compositions. Preferably the compositions are purified protein compositions. Preferably the compositions are vaccine compositions.
    Type: Application
    Filed: June 3, 2005
    Publication date: September 27, 2007
    Inventors: Martin Maiden, Ian Feavers, Andrew Pollard
  • Patent number: 6500071
    Abstract: A flexible annular coupling made of composite material and an even number of relatively thicker fixing portions (10) spaced apart circumferentially around the coupling for connection to two rotary members to be coupled by the coupling and a flexible leaf (11) extending lengthwise between each two adjacent fixing portions. Each leaf includes a relatively thinner central part (11a) and a transition portion (13) of gradually increasing thickness between the ends of the central part and the thicker fixing portions. The coupling is constructed such that the central part (11a) of at least each circumferentially alternate leaf will always be displaced axially in the same predetermined direction (A) transverse to its length when the leaf is caused to buckle by compressive force(s) acting between the fixing portions at the ends of the leaf. The displacement may be obtained by curving the central part, by suitably shaping the transitional portions or by making the central part of two layers of different stiffness.
    Type: Grant
    Filed: April 2, 2001
    Date of Patent: December 31, 2002
    Assignee: GKN Automotive GmbH
    Inventor: Andrew Pollard
  • Patent number: 5976662
    Abstract: A joint disc made of a fiber composite material with a plurality of flexible leaf elements and a plurality of angular fixing elements which are composed of laminations of fiber composite material, with the leaf elements, at each of their ends, having an increasing thickness extending at least over 10% of their length.
    Type: Grant
    Filed: February 20, 1998
    Date of Patent: November 2, 1999
    Assignee: GKN Automotive AG
    Inventors: Andrew Pollard, Russel Osborn, Wolfgang Lobel, Ludger Schachtrup
  • Patent number: 4927124
    Abstract: Assembly comprising a spring in the form of a zig-zag strip of fibre reinforced plastics material with limbs (10-16) connected by reflex portions (17,22), wherein end limbs (10,16) of the spring are mounted at an attitude they would adopt when loaded if they were pin-jointed so as to be free to move as the spring is loaded so that over-stressing of the reflex portions (18,21) of the spring is thereby avoided when the spring is loaded. In modifications of the invention, a spring end limb (39) may be progressively engaged by a surface (42) of a mounting to be supported at a range of attitudes corresponding to a range of spring loads; or a spring mounting may be associated with pivotable members so that end limbs of the spring move arcuately therewith and change their relative attitude as if they were pin-jointed.
    Type: Grant
    Filed: December 2, 1988
    Date of Patent: May 22, 1990
    Assignee: GKN Technology Limited
    Inventors: Colin E. Spedding, Andrew Pollard
  • Patent number: 4887841
    Abstract: A suspension for a pair of wheels of a motor vehicle, comprising a spring (10,30) extending tranversely of the vehicle and supported by two mountings (11,12) spaced between the spring ends and which ends are connected, directly or indirectly, to wheel carrier members, wherein the spring has a portion (22,24) displaced out of the general line of adjacent parts of the spring to give a clearance from a part of the vehicle. The displaced part of the spring may be the entire central portion (40,50,60,100) thereof between its mountings (45,46,101) and end portions of the spring may be inclined to such central portion, so that the space directly between the wheels is clear of suspension parts.
    Type: Grant
    Filed: June 6, 1988
    Date of Patent: December 19, 1989
    Assignee: GKN Technology Limited
    Inventors: David Cowburn, Stephen P. Rawlings, Andrew Pollard