Patents by Inventor Gary Clayman

Gary Clayman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolation of a cell-specific internalizing peptide that infiltrates tumor tissue for targeted drug delivery
    Publication number: 20060188437
    Abstract: The present invention provides a tumor-homing peptide that can target cancer and or tumor tissues. The peptide is uptaken by certain specific cancer cell types. The invention describes methods to achieve targeted delivery of anticancer drugs conjugated to this peptide for anticancer therapy. The invention also describes methods for using the peptide for the diagnosis and imaging of cancer and tumor tissues.
    Type: Application
    Filed: February 8, 2005
    Publication date: August 24, 2006
    Inventors: Frank Hong, Gary Clayman
  • Methods and compositions for the diagnosis and treatment of cancer
    Publication number: 20060035857
    Abstract: Methods for the treatment of squamous cell carcinoma using a p53-expressing viral vector are disclosed. In particular embodiments, the vector is a replication-deficient adenovirus. In addition, there are provided methods for examining the development and treatment of microscopic residual disease in the context of post-surgical environments and in body cavities.
    Type: Application
    Filed: August 9, 2005
    Publication date: February 16, 2006
    Inventor: Gary Clayman
  • Isolation of a cell-specific internalizing peptide that infiltrates tumor tissue for targeted drug delivery
    Patent number: 6919425
    Abstract: The present invention provides a tumor-homing peptide that can target cancer and or tumor tissues. The peptide is uptaken by certain specific cancer cell types. The invention describes methods to achieve targeted delivery of anticancer drugs conjugated to this peptide for anticancer therapy. The invention also describes methods for using the peptide for the diagnosis and imaging of cancer and tumor tissues.
    Type: Grant
    Filed: July 2, 2001
    Date of Patent: July 19, 2005
    Assignee: Board of Regents, The University of Texas System
    Inventors: Frank D. Hong, Gary Clayman
  • Methods and compositions of a novel serine protease inhibitor
    Publication number: 20040180371
    Abstract: The present invention describes a novel gene encoding a novel protein termed headpin (for head and neck serpin) that is homologous to known serine protease inhibitors. The invention describes methods and compositions of the nucleic acids, encoded proteins, antibodies, pharmaceuticals, cancer treatments, diagnostics and screens for modulators of headpin.
    Type: Application
    Filed: January 28, 2004
    Publication date: September 16, 2004
    Applicant: Board of Regents, The University of Texas System
    Inventors: Gary Clayman, Torahiko Nakashima, Paul Spring
  • Isolation of a cell-specific internalizing peptide that infiltrates tumor tissue for targeted drug delivery
    Publication number: 20020102265
    Abstract: The present invention provides a tumor-homing peptide that can target cancer and or tumor tissues. The peptide is uptaken by certain specific cancer cell types. The invention describes methods to achieve targeted delivery of anticancer drugs conjugated to this peptide for anticancer therapy. The invention also describes methods for using the peptide for the diagnosis and imaging of cancer and tumor tissues.
    Type: Application
    Filed: July 2, 2001
    Publication date: August 1, 2002
    Inventors: Frank D. Hong, Gary Clayman