Patents by Inventor Giovanni Pastrone

Giovanni Pastrone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080065008
    Abstract: A balloon arterial cannula and methods for filtering blood. The devices generally include a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta, a structure adapted to open and close the mesh within the blood vessel, a means to actuate the structure, and a balloon occluder which typically includes a flexible material enclosing a chamber. The methods generally include the steps of introducing a mesh into a blood vessel to capture embolic material, adjusting the mesh, if necessary, during the course of filtration, inflating the balloon occluder to occlude the vessel upstream of the mesh, and thereafter deflating the balloon occluder and removing the mesh and the captured foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.
    Type: Application
    Filed: November 16, 2007
    Publication date: March 13, 2008
    Inventors: Denise Barbut, Jonathan Root, Giovanni Pastrone, Tracy Maahs, Ross Tsugita
  • Patent number: 7306575
    Abstract: A balloon arterial cannula and methods for filtering blood. The devices generally include a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta, a structure adapted to open and close the mesh within the blood vessel, a means to actuate the structure, and a balloon occluder which typically includes a flexible material enclosing a chamber. The methods generally include the steps of introducing a mesh into a blood vessel to capture embolic material, adjusting the mesh, if necessary, during the course of filtration, inflating the balloon occluder to occlude the vessel upstream of the mesh, and thereafter deflating the balloon occluder and removing the mesh and the captured foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.
    Type: Grant
    Filed: July 14, 2003
    Date of Patent: December 11, 2007
    Assignee: Edwards Lifesciences Corporation
    Inventors: Denise Barbut, Jonathan D. Root, Giovanni Pastrone, Tracy D. Maahs, Ross S. Tsugita
  • Publication number: 20040158276
    Abstract: A balloon arterial cannula and methods for filtering blood. The devices generally include a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta, a structure adapted to open and close the mesh within the blood vessel, a means to actuate the structure, and a balloon occluder which typically includes a flexible material enclosing a chamber. The methods generally include the steps of introducing a mesh into a blood vessel to capture embolic material, adjusting the mesh, if necessary, during the course of filtration, inflating the balloon occluder to occlude the vessel upstream of the mesh, and thereafter deflating the balloon occluder and removing the mesh and the captured foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.
    Type: Application
    Filed: July 14, 2003
    Publication date: August 12, 2004
    Applicant: Edwards Lifesciences, Inc., Irvine, CA
    Inventors: Denise Barbut, Jonathan D. Root, Giovanni Pastrone, Tracy D. Maahs, Ross S. Tsugita
  • Patent number: 6682543
    Abstract: A method for removing plaque from the aorta is disclosed. A filter is introduced into a region of interest within the patient's aorta. The filter is deployed downstream of a mobile aortic plaque within the aorta. An atherectomy assembly is operated to excise the plaque from the aorta. Emboli are captured by the filter. The filter and plaque are removed from the region of interest.
    Type: Grant
    Filed: October 24, 2001
    Date of Patent: January 27, 2004
    Assignee: C Edwards Lifesciences Corporation
    Inventors: Denise R. Barbut, Jonathan D. Root, Giovanni Pastrone
  • Patent number: 6592546
    Abstract: A balloon arterial cannula and methods for filtering blood. The devices generally include a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta, a structure adapted to open and close the mesh within the blood vessel, a means to actuate the structure, and a balloon occluder which typically includes a flexible material enclosing a chamber. The methods generally include the steps of introducing a mesh into a blood vessel to capture embolic material, adjusting the mesh, if necessary, during the course of filtration, inflating the balloon occluder to occlude the vessel upstream of the mesh, and thereafter deflating the balloon occluder and removing the mesh and the captured foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.
    Type: Grant
    Filed: January 30, 1998
    Date of Patent: July 15, 2003
    Assignee: Edwards Lifesciences Corp.
    Inventors: Denise Barbut, Jonathan D. Root, Giovanni Pastrone, Tracy D. Maahs, Ross S. Tsugita
  • Patent number: 6589264
    Abstract: A balloon arterial cannula and methods for filtering blood. The devices generally include a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta, a structure adapted to open and close the mesh within the blood vessel, a means to actuate the structure, and a balloon occluder which typically includes a flexible material enclosing a chamber. The methods generally include the steps of introducing a mesh into a blood vessel to capture embolic material, adjusting the mesh, if necessary, during the course of filtration, inflating the balloon occluder to occlude the vessel upstream of the mesh, and thereafter deflating the balloon occluder and removing the mesh and the captured foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.
    Type: Grant
    Filed: January 7, 2000
    Date of Patent: July 8, 2003
    Assignee: Edwards Lifesciences Corp.
    Inventors: Denise Barbut, Giovanni Pastrone, Tracy D. Maahs, Ross S. Tsugita
  • Publication number: 20020123761
    Abstract: A method for removing plaque from the aorta is disclosed. A filter is introduced into a region of interest within the patient's aorta. The filter is deployed downstream of a mobile aortic plaque within the aorta. An atherectomy assembly is operated to excise the plaque from the aorta. Emboli are captured by the filter. The filter and plaque are removed from the region of interest.
    Type: Application
    Filed: October 24, 2001
    Publication date: September 5, 2002
    Applicant: Scimed Life Systems, Inc.
    Inventors: Denise R. Barbut, Jonathan D. Root, Giovanni Pastrone
  • Patent number: 6309399
    Abstract: An arterial catheter system for removing plaque from the aorta and other arteries is disclosed. The system typically includes an elongate catheter member, a filtration apparatus disposed within the distal region, and an atherectomy assembly which includes a mechanism for trapping and holding mobile or fixed plaque and an excising mechanism for removing the plaque. In use, the catheter is positioned so that the atherectomy assembly lies within a region of interest, the filtration apparatus is deployed downstream of the region of interest, the plaque is trapped and held by a snare, vacuum, or other trapping means, and then the excising mechanism is activated to remove the plaque. Methods are also disclosed for removing plaque from the aorta and other arteries.
    Type: Grant
    Filed: September 7, 2000
    Date of Patent: October 30, 2001
    Assignee: SciMed Life Systems, Inc.
    Inventors: Denise R. Barbut, Jonathan D. Root, Giovanni Pastrone
  • Patent number: 6179851
    Abstract: An arterial catheter system for removing plaque from the aorta and other arteries is disclosed. The system typically includes an elongate catheter member, a filtration apparatus disposed within the distal region, and an atherectomy assembly which includes a mechanism for trapping and holding mobile or fixed plaque and an excising mechanism for removing the plaque. In use, the catheter is positioned so that the atherectomy assembly lies within a region of interest, the filtration apparatus is deployed downstream of the region of interest, the plaque is trapped and held by a snare, vacuum, or other trapping device, and then the excising mechanism is activated to remove the plaque. Methods are also disclosed for removing plaque from the aorta and other arteries.
    Type: Grant
    Filed: June 15, 1999
    Date of Patent: January 30, 2001
    Assignee: SciMed Life Systems, Inc.
    Inventors: Denise R. Barbut, Jonathan D. Root, Giovanni Pastrone
  • Patent number: 6157703
    Abstract: An x-ray beam hardening filter is disclosed. The x-ray beam hardening filter comprises a support member and a beam hardening sheet, the beam hardening sheet having a multidimensional array of regularly spaced apertures. The apertures are configured to have an x-ray transmissive quality. An actuator, engaging the support member, is capable of moving the multidimensional array of apertures into or out of a path of an x-ray beam, thereby selectively introducing varying levels of x-ray energy filtration. In one embodiment, multiple layers of beam hardening sheets are added to the x-ray beam hardening filter to create additional levels of x-ray energy filtration. Advantages of the x-ray beam hardening filter include the relatively small distance the x-ray beam hardening filter must move in order to absorb the incident x-ray beam, the ability to introduce varying levels of x-ray filtration, and the compact structure of the x-ray beam hardening filter.
    Type: Grant
    Filed: October 6, 1998
    Date of Patent: December 5, 2000
    Assignee: Cardiac Mariners, Inc.
    Inventors: Edward G. Solomon, Giovanni Pastrone
  • Patent number: 6118854
    Abstract: An x-ray beam hardening filter and method for making the same is disclosed. According to an embodiment, the method comprises etching a plurality of regularly spaced pits into a surface area of a sheet having an x-ray beam hardening quality, aligning the sheet to a support member and bonding the sheet to the support member. An x-ray beam hardening filter can be made and used which is not only compact and useful in diagnostic x-ray imaging, but which is capable of shaping an x-ray energy spectrum envelope in a highly controllable manner.
    Type: Grant
    Filed: October 6, 1998
    Date of Patent: September 12, 2000
    Assignee: Cardiac Mariners, Inc.
    Inventors: Edward G. Solomon, Giovanni Pastrone
  • Patent number: 6090097
    Abstract: A balloon arterial cannula and methods for filtering blood. The devices generally include a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta, a structure adapted to open and close the mesh within the blood vessel, a means to actuate the structure, and a balloon occluder which typically includes a flexible material enclosing a chamber. The methods generally include the steps of introducing a mesh into a blood vessel to capture embolic material, adjusting the mesh, if necessary, during the course of filtration, inflating the balloon occluder to occlude the vessel upstream of the mesh, and thereafter deflating the balloon occluder and removing the mesh and the captured foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.
    Type: Grant
    Filed: January 16, 1998
    Date of Patent: July 18, 2000
    Assignee: Embol-X, Inc.
    Inventors: Denise Barbut, Giovanni Pastrone, Tracy D. Maahs, Ross S. Tsugita
  • Patent number: 6060713
    Abstract: A detector comprising a plurality of densely packed x-ray detectors arranged into an array. Each detector preferably comprises a scintillator element which is optically coupled to a photodetector element, preferably with a fiber optic link. Each photodetector element is preferably optically separate from adjacent photodetector elements. The detector array preferably includes integral alignment means to align the scintillator elements with the photodetector elements. The scintillator array elements are preferably formed from materials which possess a fast response and a minimum afterglow time.
    Type: Grant
    Filed: September 11, 1998
    Date of Patent: May 9, 2000
    Inventors: Brian Skillicorn, Giovanni Pastrone
  • Patent number: 6010522
    Abstract: An arterial catheter system for removing plaque from the aorta and other arteries is disclosed. The system typically includes an elongate catheter member, a filtration apparatus disposed within the distal region, and an atherectomy assembly which includes a mechanism for trapping and holding mobile or fixed plaque and an excising mechanism for removing the plaque. In use, the catheter is positioned so that the atherectomy assembly lies within a region of interest, the filtration apparatus is deployed downstream of the region of interest, the plaque is trapped and held by a snare, vacuum, or other trapping means, and then the excising mechanism is activated to remove the plaque. Methods are also disclosed for removing plaque from the aorta and other arteries.
    Type: Grant
    Filed: July 24, 1996
    Date of Patent: January 4, 2000
    Assignee: Embol-X, Inc.
    Inventors: Denise Barbut, Jonathan D Root, Robert Rizzari, James M Sellers, Giovanni Pastrone, John McKenzie
  • Patent number: 5997557
    Abstract: An arterial catheter system for removing plaque from the aorta and other arteries is disclosed. The system typically includes an elongate catheter member, a filtration apparatus disposed within the distal region, and an atherectomy assembly which includes a mechanism for trapping and holding mobile or fixed plaque and an excising mechanism for removing the plaque. In use, the catheter is positioned so that the atherectomy assembly lies within a region of interest, the filtration apparatus is deployed downstream of the region of interest, the plaque is trapped and held by a snare, vacuum, or other trapping means, and then the excising mechanism is activated to remove the plaque. Methods are also disclosed for removing plaque from the aorta and other arteries.
    Type: Grant
    Filed: February 11, 1998
    Date of Patent: December 7, 1999
    Assignee: Embol-X, Inc.
    Inventors: Denise Barbut, Jonathan D. Root, Robert Rizzari, James M. Sellers, Giovanni Pastrone, John McKenzie
  • Patent number: 5993469
    Abstract: An arterial catheter system for removing plaque from the aorta and other arteries is disclosed. The system typically includes an elongate catheter member, a filtration apparatus disposed within the distal region, and an atherectomy assembly which includes a mechanism for trapping and holding mobile or fixed plaque and an excising mechanism for removing the plaque. In use, the catheter is positioned so that the atherectomy assembly lies within a region of interest, the filtration apparatus is deployed downstream of the region of interest, the plaque is trapped and held by a snare, vacuum, or other trapping means, and then the excising mechanism is activated to remove the plaque. Methods are also disclosed for removing plaque from the aorta and other arteries.
    Type: Grant
    Filed: May 27, 1997
    Date of Patent: November 30, 1999
    Assignee: Embol-X, Inc.
    Inventors: John McKenzie, Giovanni Pastrone
  • Patent number: 5980555
    Abstract: Devices and methods for filtering blood. The devices generally comprise: a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta; a structure adapted to open and close the mesh within the blood vessel; and a means to actuate the structure. The methods generally include the following steps: introducing a mesh into a blood vessel to entrap embolic material; adjusting the mesh, if necessary, during the course of filtration; and removing the mesh and the entrapped foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.
    Type: Grant
    Filed: November 14, 1997
    Date of Patent: November 9, 1999
    Assignee: Embol-X, Inc.
    Inventors: Denise Barbut, Jonathan D. Root, Giovanni Pastrone, James M. Sellers, Robert Rizzari
  • Patent number: 5895399
    Abstract: An arterial catheter system for removing plaque from the aorta and other arteries is disclosed. The system typically includes an elongate catheter member, a filtration apparatus disposed within the distal region, and an atherectomy assembly which includes a mechanism for trapping and holding mobile or fixed plaque and an excising mechanism for removing the plaque. In use, the catheter is positioned so that the atherectomy assembly lies within a region of interest, the filtration apparatus is deployed downstream of the region of interest, the plaque is trapped and held by a snare, vacuum, or other trapping means, and then the excising mechanism is activated to remove the plaque. Methods are also disclosed for removing plaque from the aorta and other arteries.
    Type: Grant
    Filed: October 9, 1996
    Date of Patent: April 20, 1999
    Assignee: Embol-X Inc.
    Inventors: Denise Barbut, Jonathan D Root, Robert Rizzari, James M Sellers, Giovanni Pastrone, John McKenzie
  • Patent number: 5808306
    Abstract: The detector of the present invention comprises a plurality of densely packed x-ray detectors arranged into an array. Each detector preferably comprises a scintillator element which is optically coupled to a photodetector element, preferably with a fiber optic link. Each photodetector element is preferably optically separate from adjacent photodetector elements. The detector array preferably includes integral alignment means to align the scintillator elements with the photodetector elements. The scintillator array elements are preferably formed from materials which possess a fast response and a minimum afterglow time.
    Type: Grant
    Filed: August 26, 1996
    Date of Patent: September 15, 1998
    Assignee: Cardiac Mariners, Inc.
    Inventors: Brian Skillicorn, Giovanni Pastrone
  • Patent number: 5769816
    Abstract: Devices and methods for filtering blood. The devices generally comprise: a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta; a structure adapted to open and close the mesh within the blood vessel; and a means to actuate the structure. The methods generally include the following steps: introducing a mesh into a blood vessel to entrap embolic material; adjusting the mesh, if necessary, during the course of filtration; and removing the mesh and the entrapped foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.
    Type: Grant
    Filed: April 30, 1996
    Date of Patent: June 23, 1998
    Assignee: Embol-X, Inc.
    Inventors: Denise Barbut, Jonathan D. Root, Giovanni Pastrone, James M. Sellers, Robert Rizzari