Patents by Inventor James Raymond Brown

James Raymond Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptidyl t-RNA hydrolase (PTH)
    Patent number: 7202071
    Abstract: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: May 14, 2003
    Date of Patent: April 10, 2007
    Assignee: SmithKline Beecham Corporation
    Inventors: Sanjoy Biswas, James Raymond Brown, Christine Debouck, Deborah Dee Jaworski, Elizabeth Jane Lawlor, Jeffrey Mooney, Lisa Kathleen Shilling, Min Wang, Richard Lloyd Warren, Magdalena Zalacain, Yi Yi Zhong, John Peter Throup, Karen Anne Ingraham, Alison Frances Chalker, David John Holmes, Christopher Michael Traini
  • Ornithine carbamoyltransferase
    Patent number: 6706508
    Abstract: The invention provides ornithine carbamoyltransferase polypeptides and DNA (RNA) encoding ornithine carbamoyltransferase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ornithine carbamoyltransferase polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: November 2, 1999
    Date of Patent: March 16, 2004
    Assignee: SmithKline Beecham Corporation
    Inventors: James Raymond Brown, Magdalena Zalacain
  • Novel pth
    Publication number: 20030232373
    Abstract: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: May 14, 2003
    Publication date: December 18, 2003
    Applicant: SmithKline Beecham Corporation
    Inventors: Sanjoy Biswas, James Raymond Brown, Christine Debouck, Deborah Dee Jaworski, Elizabeth Jane Lawlor, Jeffrey Mooney, Lisa Kathleen Shilling, Min Wang, Richard Lloyd Warren, Magdalena Zalacain, Yi Yi Zhong, John Peter Throup, Karen Anne Ingraham, Alison Frances Chalker, David John Holmes, Christopher Michael Traini
  • AmpS from Streptococus pneumoniae
    Patent number: 6558919
    Abstract: The invention provides ampS polypeptides and DNA (RNA) encoding ampS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ampS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: December 4, 1998
    Date of Patent: May 6, 2003
    Assignee: SmithKline Beecham Corporation
    Inventors: Magdalena Zalacain, James Raymond Brown
  • Map
    Publication number: 20030082614
    Abstract: The invention provides map polypeptides and polynucleotides encoding map polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing map polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: September 26, 2002
    Publication date: May 1, 2003
    Inventors: Sanjoy Biswas, James Raymond Brown, Martin K. R. Burnham, Alison Francis Chalker, David John Holmes, Karen Anne Ingraham, Thomas B. Mathie, Richard Lloyd Warren, Magdalena Zalacain
  • ndp
    Publication number: 20030017532
    Abstract: The invention provides ndp polypeptides and polynucleotides encoding ndp polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ndp polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: July 27, 2001
    Publication date: January 23, 2003
    Inventors: SanJoy Biswas, James Raymond Brown, Martin Karl Russel Burnham, Alison Francis Chalker, David John Holmes, Karen Anne Ingraham, Thomas B. Mathie, Richard Lloyd Warren, Magdalena Zalacain
  • Map
    Publication number: 20020150963
    Abstract: The invention provides map polypeptides and polynucleotides encoding map polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing map polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: May 29, 2001
    Publication date: October 17, 2002
    Inventors: Sanjoy Biswas, James Raymond Brown, Martin K.R. Burnham, Alison Francis Chalker, David John Holmes, Karen Anne Ingraham, Thomas B. Mathie, Richard Lloyd Warren, Magdalena Zalacain
  • murF2
    Publication number: 20020127596
    Abstract: The invention provides murF2 polypeptides and polynucleotides encoding murF2 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing murF2 polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: December 13, 2000
    Publication date: September 12, 2002
    Inventors: Sanjoy Biswas, James Raymond Brown, Martin K. R. Burnham, Alison Francis Chalker, David John Holmes, Karen Anne Ingraham, Thomas Berthold Mathie, Richard Lloyd Warren, Magdalena Zalacain
  • Novel histidine kinase
    Publication number: 20020123119
    Abstract: The invention provides histidine kinase polypeptides and DNA (RNA) encoding histidine kinase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing histidine kinase polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: September 10, 2001
    Publication date: September 5, 2002
    Inventors: James Raymond Brown, Nicola Gail Wallis, Magdalena Zalacain, Sanjoy Biswas, John Throup
  • nusB
    Publication number: 20020091237
    Abstract: The invention provides nusB polypeptides and polynucleotides encoding nusB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing nusB polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: May 24, 2001
    Publication date: July 11, 2002
    Inventors: Sanjoy Biswas, James Raymond Brown, Martin Karl Russel Burnham, Alison Francis Chalker, David John Holmes, Karen Anne Ingraham, Chi Young So, Richard Lloyd Warren, Magdalena Zalacain
  • inFB
    Patent number: 6399343
    Abstract: The invention provides infB polypeptides and polynucleotides encoding infB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing in polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: May 19, 2000
    Date of Patent: June 4, 2002
    Assignee: SmithKline Beecham Corporation
    Inventors: Sanjoy Biswas, James Raymond Brown, Martin Karl Russel Burnham, Alison Francis Chalker, Richard Lloyd Warren, Magdalena Zalacain, Chi Young So, Christopher M Traini, David John Holmes, Karen Anne Ingraham, Thomas B Mathie
  • Novel pth
    Publication number: 20020058799
    Abstract: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: May 2, 2001
    Publication date: May 16, 2002
    Inventors: Sanjoy Biswas, James Raymond Brown, Christine Debouck, Deborah Dee Jaworski, Elizabeth Jane Lawlor, Jeffrey Mooney, Lisa Kathleen Shilling, Min Wang, Richard Lloyd Warren, Magdalena Zalacain, Yi Yi Zhong, John Peter Throup, Karen Anne Ingraham, Alison Frances Chalker, David John Holmes, Christopher Michael Traini
  • trmD
    Patent number: 6350600
    Abstract: The invention provides trmA methyl transferase (trmD) polypeptides and polynucleotides encoding trmD polypeptides and methods for producing such polypeptides by recominant techniques from strepococcus pneumoniae. Also provided are methods for utilizing polypepides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 28, 2000
    Date of Patent: February 26, 2002
    Assignee: SmithKline Beecham Corp.
    Inventors: Sanjoy Biswas, James Raymond Brown, Chi Young So, Alison Francis Chalker, David John Holmes, Karen Anne Ingraham, Thomas B Mathie, Richard Lloyd Warren, Magdalena Zalacain
  • Apt
    Patent number: 6348578
    Abstract: The invention provides apt polypeptides and DNA (RNA) encoding apt polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing apt polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: October 14, 1999
    Date of Patent: February 19, 2002
    Assignees: SmithKline Beecham Corporation, SmithKline Beecham plc
    Inventors: Michael Arthur Lonetto, Richard Oakley Nicholas, James Raymond Brown, Michael Terence Black, John Edward Hodgson, David Justin Charles Knowles, Robert King Stodola, Magdalena Zalacain
  • Novel spoIIIE
    Publication number: 20020019515
    Abstract: The invention provides spoIIIE polypeptides and DNA (RNA) encoding spoIIIE polypeptides and methods for producing such polypeptides by recomombinant techniques. Also provided are methods for utilizing spoIIIE polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: February 2, 2001
    Publication date: February 14, 2002
    Inventors: Alison Frances Chalker, Maria Magdalena Zalacain Feliu, James Raymond Brown, Alexander Philip Bryant
  • yhxB
    Patent number: 6340564
    Abstract: The invention provides yhxB polypeptides and polynucleotides encoding yhxB polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing yhxB polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: January 26, 1999
    Date of Patent: January 22, 2002
    Assignee: SmithKline Beecham Corporation
    Inventors: Karen Anne Ingraham, Chi Yong So, Stephanie Van Horn, Alison Francis Chalker, David John Holmes, Sanjoy Biswas, James Raymond Brown, Martin Karl Russel Burnham, Patrick Vernon Warren, Richard Lloyd Warren, Magdalena Zalacain
  • Pth
    Patent number: 6303771
    Abstract: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: May 18, 1998
    Date of Patent: October 16, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Sanjoy Biswas, James Raymond Brown, Christine Debouck, Deborah Dee Jaworski, Elizabeth Jane Lawlor, Jeffrey Mooney, Lisa Kathleen Shilling, Min Wang, Richard Lloyd Warren, Magdalena Zalacain, Yi Yi Zhong, John Peter Throup, Karen Anne Ingraham, Alison Frances Chalker, David John Holmes, Christopher Michael Traini
  • Amps from Streptococcus pneumoniae
    Patent number: 6297039
    Abstract: The invention provides ampS polypeptides and DNA (RNA) encoding ampS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ampS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: December 4, 1998
    Date of Patent: October 2, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: Magdalena Zalacain, James Raymond Brown
  • yfjO
    Publication number: 20010023064
    Abstract: The invention provides yfjO polypeptides and polynucleotides encoding yfjO polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing yfjO polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: December 13, 2000
    Publication date: September 20, 2001
    Inventors: Sanjoy Biswas, Alexander Bryant, James Raymond Brown, Alison Francis Chalker, David John Holmes, Karen Anne Ingraham, Chi Young So, Stephanie Van Horn, Richard Lloyd Warren, Magdalena Zalacain
  • Histidine kinase from Streptococcus pneumoniae and compositions therecontaining
    Patent number: 6287836
    Abstract: The invention provides histidine kinases polypeptides from Streptococcus pneumoniae, fusion polypeptides containing said histidine kinases and truncations of said histidine kinases. The invention also provides compositions comprising histidine kinases from Streptococcus pneumoniae, fusion polypeptides containing said histidine kinases and truncations of said histidine kinases.
    Type: Grant
    Filed: October 8, 1997
    Date of Patent: September 11, 2001
    Assignee: SmithKline Beecham Corporation
    Inventors: James Raymond Brown, Nicola Gail Wallis, Magdalena Zalacain, Sanjoy Biswas, John Throup