Patents by Inventor Magdalena Zalacain

Magdalena Zalacain has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHEMICAL COMPOUNDS
    Publication number: 20220315546
    Abstract: The invention relates to a compound which is a thiazole derivative of Formula (I), or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, R7, , Z, L, X, m, n and p are as defined herein. The compounds are useful in the treatment and prevention of bacterial infection. The invention also relates to combinations of the compound of Formula (I) with further active agents.
    Type: Application
    Filed: March 4, 2022
    Publication date: October 6, 2022
    Applicant: Antabio SAS
    Inventors: David Thomas DAVIES, Simon LEIRIS, Nicolas SPRYNSKI, Martin EVERETT, Magdalena ZALACAIN
  • Chemical compounds
    Patent number: 11299467
    Abstract: The invention relates to a compound which is a thiazole derivative of Formula (I), or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, R7, Formula (A), Z, L, X, m, n and p are as defined herein. The compounds are useful in the treatment and prevention of bacterial infection. The invention also relates to combinations of the compound of Formula (I) with further active agents.
    Type: Grant
    Filed: July 20, 2018
    Date of Patent: April 12, 2022
    Assignee: ANTABIO SAS
    Inventors: David Thomas Davies, Simon Leiris, Nicolas Sprynski, Martin Everett, Magdalena Zalacain
  • CHEMICAL COMPOUNDS
    Publication number: 20200339526
    Abstract: The invention relates to a compound which is a thiazole derivative of Formula (I), or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, R7, Formula (A), Z, L, X, m, n and p are as defined herein. The compounds are useful in the treatment and prevention of bacterial infection. The invention also relates to combinations of the compound of Formula (I) with further active agents.
    Type: Application
    Filed: July 20, 2018
    Publication date: October 29, 2020
    Applicant: Antabio SAS
    Inventors: David Thomas DAVIES, Simon LEIRIS, Nicolas SPRYNSKI, Martin EVERETT, Magdalena ZALACAIN
  • Peptidyl t-RNA hydrolase (PTH)
    Patent number: 7202071
    Abstract: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: May 14, 2003
    Date of Patent: April 10, 2007
    Assignee: SmithKline Beecham Corporation
    Inventors: Sanjoy Biswas, James Raymond Brown, Christine Debouck, Deborah Dee Jaworski, Elizabeth Jane Lawlor, Jeffrey Mooney, Lisa Kathleen Shilling, Min Wang, Richard Lloyd Warren, Magdalena Zalacain, Yi Yi Zhong, John Peter Throup, Karen Anne Ingraham, Alison Frances Chalker, David John Holmes, Christopher Michael Traini
  • Map
    Publication number: 20060115831
    Abstract: The invention provides map polypeptides and polynucleotides encoding map polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing map polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: August 10, 2005
    Publication date: June 1, 2006
    Inventors: Sanjoy Biswas, James Brown, Martin Burnham, Alisori Chalker, David Holmes, Karen Ingraham, Thomas Mathie, Richard Warren, Magdalena Zalacain
  • Ornithine carbamoyltransferase
    Patent number: 6706508
    Abstract: The invention provides ornithine carbamoyltransferase polypeptides and DNA (RNA) encoding ornithine carbamoyltransferase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ornithine carbamoyltransferase polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: November 2, 1999
    Date of Patent: March 16, 2004
    Assignee: SmithKline Beecham Corporation
    Inventors: James Raymond Brown, Magdalena Zalacain
  • Novel pth
    Publication number: 20030232373
    Abstract: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: May 14, 2003
    Publication date: December 18, 2003
    Applicant: SmithKline Beecham Corporation
    Inventors: Sanjoy Biswas, James Raymond Brown, Christine Debouck, Deborah Dee Jaworski, Elizabeth Jane Lawlor, Jeffrey Mooney, Lisa Kathleen Shilling, Min Wang, Richard Lloyd Warren, Magdalena Zalacain, Yi Yi Zhong, John Peter Throup, Karen Anne Ingraham, Alison Frances Chalker, David John Holmes, Christopher Michael Traini
  • AmpS from Streptococus pneumoniae
    Patent number: 6558919
    Abstract: The invention provides ampS polypeptides and DNA (RNA) encoding ampS polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ampS polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: December 4, 1998
    Date of Patent: May 6, 2003
    Assignee: SmithKline Beecham Corporation
    Inventors: Magdalena Zalacain, James Raymond Brown
  • Map
    Publication number: 20030082614
    Abstract: The invention provides map polypeptides and polynucleotides encoding map polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing map polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: September 26, 2002
    Publication date: May 1, 2003
    Inventors: Sanjoy Biswas, James Raymond Brown, Martin K. R. Burnham, Alison Francis Chalker, David John Holmes, Karen Anne Ingraham, Thomas B. Mathie, Richard Lloyd Warren, Magdalena Zalacain
  • lacR from Streptococcus pneumoniae
    Patent number: 6548273
    Abstract: The invention provides lacR polypeptides and polynucleotides encoding lacR polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing lacR polypeptides to screen for antibacterial compounds.
    Type: Grant
    Filed: July 17, 2000
    Date of Patent: April 15, 2003
    Assignee: SmithKline Beecham Corporation
    Inventors: Pan Fong Chan, David J. Holmes, Michael A. Lonetto, Christopher M. Traini, Magdalena Zalacain
  • Fucose kinase
    Patent number: 6511839
    Abstract: The invention provides fucose kinase promoter polynucleotides and methods for producing and using such polynucleotides, as well as their variants, agonists and antagonists, and their uses.
    Type: Grant
    Filed: June 9, 2000
    Date of Patent: January 28, 2003
    Inventors: Pan Fong Chan, Sanjoy Biswas, David J. Holmes, Michael A. Lonetto, Leslie M. Palmer, Stephanie Van Horn, Richard L. Warren, Jr., Magdalena Zalacain
  • ndp
    Publication number: 20030017532
    Abstract: The invention provides ndp polypeptides and polynucleotides encoding ndp polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing ndp polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: July 27, 2001
    Publication date: January 23, 2003
    Inventors: SanJoy Biswas, James Raymond Brown, Martin Karl Russel Burnham, Alison Francis Chalker, David John Holmes, Karen Anne Ingraham, Thomas B. Mathie, Richard Lloyd Warren, Magdalena Zalacain
  • Map
    Publication number: 20020150963
    Abstract: The invention provides map polypeptides and polynucleotides encoding map polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing map polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: May 29, 2001
    Publication date: October 17, 2002
    Inventors: Sanjoy Biswas, James Raymond Brown, Martin K.R. Burnham, Alison Francis Chalker, David John Holmes, Karen Anne Ingraham, Thomas B. Mathie, Richard Lloyd Warren, Magdalena Zalacain
  • murF2
    Publication number: 20020127596
    Abstract: The invention provides murF2 polypeptides and polynucleotides encoding murF2 polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing murF2 polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: December 13, 2000
    Publication date: September 12, 2002
    Inventors: Sanjoy Biswas, James Raymond Brown, Martin K. R. Burnham, Alison Francis Chalker, David John Holmes, Karen Anne Ingraham, Thomas Berthold Mathie, Richard Lloyd Warren, Magdalena Zalacain
  • Novel histidine kinase
    Publication number: 20020123119
    Abstract: The invention provides histidine kinase polypeptides and DNA (RNA) encoding histidine kinase polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing histidine kinase polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: September 10, 2001
    Publication date: September 5, 2002
    Inventors: James Raymond Brown, Nicola Gail Wallis, Magdalena Zalacain, Sanjoy Biswas, John Throup
  • gcp
    Publication number: 20020119510
    Abstract: The invention provides gcp polypeptides and polynucleotides encoding gcp polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gcp polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: August 7, 2001
    Publication date: August 29, 2002
    Inventors: Sanjoy Biswas, Alison Frances Chalker, David Holmes, Karen A. Ingraham, Leslie Marie Palmer, Jennifer E. Ray, Richard Lloyd Warren, Magdalena Zalacain
  • nadE
    Publication number: 20020115075
    Abstract: The invention provides nadE polypeptides and polynucleotides encoding nadE polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing nadE polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: May 15, 2001
    Publication date: August 22, 2002
    Inventors: Sanjoy Biswas, Martin Karl Russel Burnham, Alison Francis Chalker, Karen Anne Ingraham, Christopher Michael Traini, Patrick Vernon Warren, Magdalena Zalacain
  • galK
    Publication number: 20020107217
    Abstract: The invention provides galK promoter polynucleotides and methods for producing and using such polynucleotides, as well as their variants, agonists and antagonists, and their uses.
    Type: Application
    Filed: September 17, 2001
    Publication date: August 8, 2002
    Inventors: Pan Fong Chan, David J. Holmes, Michael A. Lonetto, Stephanie Van Horn, Richard L. Warren, Magdalena Zalacain
  • pth
    Publication number: 20020106776
    Abstract: The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: June 8, 2001
    Publication date: August 8, 2002
    Inventors: Sanjoy Biswas, Martin K. Burnham, Andrew P. Fosberry, John E. Hodgson, Elizabeth J. Lawlor, Tong Li, Damien McDevitt, Christopher Michael Traini, Martin Rosenberg, Judith Ward, Richard Lloyd Warren, Magdalena Zalacain
  • metK
    Publication number: 20020102700
    Abstract: The invention provides metK polypeptides and polynucleotides encoding metK polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing metK polypeptides to screen for antibacterial compounds.
    Type: Application
    Filed: March 14, 2001
    Publication date: August 1, 2002
    Inventors: Sanjoy Biswas, Raymond Brown, Martin Karl Russel Burnham, Alison Francis Chalker, David John Holmes, Karen Anne Ingraham, Chi Young So, Richard Lloyd Warren, Magdalena Zalacain, Stephanie Van Horn