Abstract: The invention provides, inter alia, systems, compositions, kits and methods for detecting an organism, such as a microbe, microorganism, pathogen, or organism associated with Hospital Associated Infections (HAIs). The systems, compositions, kits and methods can comprise one or more probes for detecting a strain with high sensitivity, high specificity, or both. The systems, compositions, kits and methods can also be used to detect the strain within a short time frame.

Abstract: Provided herein are systems and method of detecting an organism, such as a microbe, microorganism or pathogen. The system can comprise one or more probi for detecting a strain with high sensitivity. The system can also detect the strain within a short time frame.

Abstract: The invention provides mixtures of linear nucleic acid probes, including circularizing “capture” probes, capable of massively multiplex capture of one or more sequences of interest from a plurality of target organisms. The methods provided by the invention enable rapid, precise, and economical detection of one or more organisms of interest, such as common pathogens.