Patents by Inventor Reddy Muddukrishna Chillakur

Reddy Muddukrishna Chillakur has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8551718
    Abstract: The present invention provides novel functional assay for 5-HT2A, histamine H1 or adrenergic alpha 1b receptors, by measuring intracellular cyclic adenosine monophosphate (cAMP) levels utilizing reporter gene driven cell based assay. The novel assay provides both binding affinity as well as mode of action of compounds in a single set. The novel assay of the invention is useful in identification of compounds acting through 5-HT2A, histamine H1 or adrenergic alpha 1b receptors. Furthermore, the assay offers utility in categorizing compounds in to agonist, partial agonist, inverse agonist and antagonist classes. The novel assay can be scaled up to any high throughput format.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: October 8, 2013
    Assignee: Suven Life Science Limited
    Inventors: Ishtiyaque Ahmad, Reddy Venkat Mekala, Reddy Muddukrishna Chillakur, Ramkumar Subramaniam, Jyothsna Ravula, Sriramachandra Murthy Patnala, Ramakrishna Nirogi, Venkateswarlu Jasti
  • Publication number: 20120315657
    Abstract: The present invention provides novel functional assay for 5-HT2A, histamine H1 or adrenergic alpha 1b receptors, by measuring intracellular cyclic adenosine monophosphate (cAMP) levels utilizing reporter gene driven cell based assay. The novel assay provides both binding affinity as well as mode of action of compounds in a single set. The novel assay of the invention is useful in identification of compounds acting through 5-HT2A, histamine H1 or adrenergic alpha 1b receptors. Furthermore, the assay offers utility in categorizing compounds in to agonist, partial agonist, inverse agonist and antagonist classes. The novel assay can be scaled up to any high throughput format.
    Type: Application
    Filed: March 31, 2010
    Publication date: December 13, 2012
    Applicant: SUVEN LIFE SCIENCES LIMITED
    Inventors: Ishtiyaque Ahmad, Reddy Venkat Mekala, Reddy Muddukrishna Chillakur, Ramkumar Subramaniam, Jyothsna Ravula, Sriramachandra Murthy Patnala, Ramakrishna Nirogi, Venkateswarlu Jasti