Patents by Inventor Tian-Qiang Sun

Tian-Qiang Sun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MULTIVALENT PARTICLES COMPOSITIONS AND METHODS OF USE
    Publication number: 20220332769
    Abstract: Provided herein are multivalent particles and compositions of multivalent particles for blocking viral infection.
    Type: Application
    Filed: June 30, 2022
    Publication date: October 20, 2022
    Inventors: Chang-Zheng Chen, Guoqiang Dong, Yiling Luo, Hua Zhou, Tian-Qiang Sun, Michael Chen
  • Multivalent particles compositions and methods of use
    Patent number: 11453705
    Abstract: Provided herein are multivalent particles and compositions of multivalent particles for blocking viral infection.
    Type: Grant
    Filed: October 29, 2021
    Date of Patent: September 27, 2022
    Assignee: ACHELOIS BIOPHARMA, INC.
    Inventors: Chang-Zheng Chen, Guoqiang Dong, Yiling Luo, Hua Zhou, Tian-Qiang Sun, Michael Chen
  • METHODS OF MODULATING CD160 FUNCTION IN THE ANTIGEN-SPECIFIC IMMUNE CELL AND USES THEREOF
    Publication number: 20220152098
    Abstract: The present invention provides modified antigen-specific immune cells expressing an exogenous CD 160 protein. In some embodiments, the modified antigen-specific immune cell further comprises a functional exogenous receptor, such as an engineered TCR or a CAR. The present invention also provides methods of modulating CD 160 activity in antigen-specific immune cells. The present invention also provides methods and pharmaceutical compositions for cancer treatment using the modified antigen-specific immune cells and the modulators of CD 160 activity described herein.
    Type: Application
    Filed: February 28, 2020
    Publication date: May 19, 2022
    Inventors: Chang-Zheng CHEN, Hua ZHOU, Tian-Qiang SUN, Yiling LUO, Guoqiang DONG
  • MULTIVALENT PARTICLES COMPOSITIONS AND METHODS OF USE
    Publication number: 20220135626
    Abstract: Provided herein are multivalent particles and compositions of multivalent particles for blocking viral infection.
    Type: Application
    Filed: October 29, 2021
    Publication date: May 5, 2022
    Inventors: Chang-Zheng Chen, Guoqiang Dong, Yiling Luo, Hua Zhou, Tian-Qiang Sun, Michael Chen
  • METHODS FOR USING AND BIOMARKERS FOR AMPK-ACTIVATING COMPOUNDS
    Publication number: 20150087673
    Abstract: Disclosed are methods of using AMPK-activating compounds, for example, in the treatment of cancer and disorders of vascular flow. Also disclosed are biomarkers for AMPK and uses thereof, for example, in the diagnosis and treatment of AMPK-linked disorders. In certain embodiments, the AMPK-activating compounds have the structural formula wherein E, J, T, D1, D2, D3, the ring system denoted by “B”, T, R3, R4, w and x are as described herein.
    Type: Application
    Filed: September 26, 2014
    Publication date: March 26, 2015
    Applicant: RIGEL PHARMACEUTICALS, INC.
    Inventors: Yasumichi Hitoshi, Yonchu Jenkins, Vadim Markovtsov, Todd Kinsella, Tian-Qiang Sun
  • Isolated dishevelled associated kinases, polynucleotides encoding the kinases, and methods of use thereof
    Patent number: 6958238
    Abstract: The invention provides Dishevelled Associated Kinase polypeptides, which phosphorylate Dsh proteins involved in the Wnt/Wg signalling pathway. Isolated polynucleotides encoding DAK polypeptides are further provided, as are recombinant vectors, and host cells comprising the polynucleotides. Methods of using the polynucleotides and polypeptides of the invention are further aspects of the invention, including assays to detect agents which modulate DAK kinase activity. Further provided are methods of modulating pathways involved in control of cell proliferation.
    Type: Grant
    Filed: June 18, 2003
    Date of Patent: October 25, 2005
    Assignee: The Regents of the University of California
    Inventors: Tian-Qiang Sun, Lewis T. Williams
  • Isolated dishevelled associated kinases, polynucleotides encoding the kinases, and methods of use thereof
    Publication number: 20040005688
    Abstract: The invention provides Dishevelled Associated Kinase polypeptides, which phosphorylate Dsh proteins involved in the Wnt/Wg signalling pathway. Isolated polynucleotides encoding DAK polypeptides are further provided, as are recombinant vectors, and host cells comprising the polynucleotides. Methods of using the polynucleotides and polypeptides of the invention are further aspects of the invention, including assays to detect agents which modulate DAK kinase activity. Further provided are methods of modulating pathways involved in control of cell proliferation.
    Type: Application
    Filed: June 18, 2003
    Publication date: January 8, 2004
    Inventors: Tian-Qiang Sun, Lewis T. Williams
  • Isolation of drosophila and human polynucleotides encoding PAR-1 kinase, polypeptides encoded by the polynucleotides and methods utilizing the polynucleotides and polypeptides
    Publication number: 20020115167
    Abstract: Isolated nucleic acid molecules comprising polynucleotide having sequences that encode human and Drosophila PAR-1 kinases. Also provided are proteins and polypeptides encoded by the nucleic acid molecules, methods of modulating PAR-1 expression and function, and methods of modulating the Wnt signaling pathway.
    Type: Application
    Filed: July 30, 2001
    Publication date: August 22, 2002
    Inventors: Tian-Qiang Sun, Jia-Jia Feng, Christoph Reinhard, Wendy J. Fantl, Lewis T. Williams