Patents by Inventor Vladimir Bajic

Vladimir Bajic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170209412
    Abstract: The present invention includes embodiments for treatment and/or prevention of sickle cell disease that employ Hydroxyfasudil or Isocoronarin D alone or either in conjunction with each other or an inducer of HbF production. The compounds may act synergistically, and the compounds employed circumvent the side effects seen with Hydroxyurea.
    Type: Application
    Filed: April 10, 2017
    Publication date: July 27, 2017
    Inventors: Megbubah Essack, Vladimir Bajic, Aleksandar Radovanovic
  • Patent number: 9655905
    Abstract: The present invention includes embodiments for treatment and/or prevention of sickle cell disease that employ Hydroxyfasudil or Isocoronarin D alone or either in conjunction with each other or an inducer of HbF production. The compounds may act synergistically, and the compounds employed circumvent the side effects seen with Hydroxyurea.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: May 23, 2017
    Assignee: KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Magbubah Essack, Vladimir Bajic, Aleksandar Radovanovic
  • Publication number: 20150292025
    Abstract: Different combinations of methylation status based biomarkers can be used to test for prostate cancer with high sensitivity and high specificity.
    Type: Application
    Filed: June 11, 2013
    Publication date: October 15, 2015
    Applicant: KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Vladimir Bajic, Hicham Mansour, Roberto Incitti
  • Publication number: 20150284809
    Abstract: Embodiments of the present invention concern methods and compositions related to detection of ovarian cancer, including detection of the stage of ovarian cancer, in some cases. In particular, the invention encompasses use of expression of TFAP2A and in some embodiments CA125 and/or E2F5 to identify ovarian cancer, including detecting mRNA and/or protein levels of the respective gene products. Kits for detection of ovarian cancer are also described.
    Type: Application
    Filed: June 9, 2015
    Publication date: October 8, 2015
    Applicant: KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Vladimir Bajic, Mandeep Kaur
  • Publication number: 20150164858
    Abstract: The present invention generally concerns particular methods and compositions for treatment of a neurodegenerative disease, such as Alzheimer's Disease. In particular embodiments, there is a composition comprising Parthenolide and a second agent, including an inhibitor of TLR4/MD-2/CD14, nAChR agonist, Resatorvid, Curcumin, Tilorone or a Tilorone analog, or a combination thereof.
    Type: Application
    Filed: May 22, 2013
    Publication date: June 18, 2015
    Inventors: Vladimir Bajic, Magbubah Essack
  • Patent number: 9057107
    Abstract: Embodiments of the present invention concern methods and compositions related to detection of ovarian cancer, including detection of the stage of ovarian cancer, in some cases. In particular, the invention encompasses use of expression of TFAP2A and in some embodiments CA125 and/or E2F5 to identify ovarian cancer, including detecting mRNA and/or protein levels of the respective gene products. Kits for detection of ovarian cancer are also described.
    Type: Grant
    Filed: March 8, 2012
    Date of Patent: June 16, 2015
    Assignee: King Abdullah University of Science and Technology
    Inventors: Vladimir Bajic, Mandeep Kaur
  • Publication number: 20150141262
    Abstract: Different combinations of methylation status based biomarkers can be used to test for breast cancer with high sensitivity and high specificity.
    Type: Application
    Filed: June 11, 2013
    Publication date: May 21, 2015
    Applicant: KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Vladimir Bajic, Hicham Mansour, Roberto Incitti
  • Publication number: 20140356458
    Abstract: The present invention includes embodiments for treatment and/or prevention of sickle cell disease that employ Hydroxyfasudil or Isocoronarin D alone or either in conjunction with each other or an inducer of HbF production. The compounds may act synergistically, and the compounds employed circumvent the side effects seen with Hydroxyurea.
    Type: Application
    Filed: September 13, 2012
    Publication date: December 4, 2014
    Applicant: KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Magbubah Essack, Vladimir Bajic, Aleksandar Radovanovic
  • Publication number: 20140255418
    Abstract: The present invention concerns particular biomarkers for diagnosing and/or prognosticating colorectal cancer, in particular in a non-invasive manner. The methods and compositions concern analysis of methylation patterns of one or more genes from a set of 29 genes identified as described herein. In certain embodiments, the gene set includes at least P15.INK4b, SST, GAS7, CNRIP1, and PIK3CG.
    Type: Application
    Filed: October 16, 2012
    Publication date: September 11, 2014
    Inventors: Hicham Mansour, Roberto Incitti, Vladimir Bajic
  • Publication number: 20140199696
    Abstract: Different combinations of methylation status based biomarkers can be used to test for ovarian cancer with high sensitivity and high specificity.
    Type: Application
    Filed: January 13, 2014
    Publication date: July 17, 2014
    Applicant: King Abdullah University of Science and Technology
    Inventors: Hicham Mansour, Roberto Incitti, Vladimir Bajic
  • Publication number: 20120231090
    Abstract: Embodiments of the present invention concern methods and compositions related to detection of ovarian cancer, including detection of the stage of ovarian cancer, in some cases. In particular, the invention encompasses use of expression of TFAP2A and in some embodiments CA125 and/or E2F5 to identify ovarian cancer, including detecting mRNA and/or protein levels of the respective gene products. Kits for detection of ovarian cancer are also described.
    Type: Application
    Filed: March 8, 2012
    Publication date: September 13, 2012
    Inventors: Vladimir Bajic, Mandeep Kaur