Abstract: Techniques for suppression of motion artifacts in medical imaging include obtaining projections at different times within a time interval from a medical imaging system operating on a subject. A stationary projection is determined for a first subset of the projections in which a signal source and detector array of the imaging system are in a first configuration relative to the subject. An image of the subject based on the stationary projection is displayed. For any subset, the stationary projection is a minimum value for each pixel among the subset of projections if a signal passing through a moving object of interest inside the subject is expected to cause an increase in a pixel value. Alternatively, the stationary projection is a maximum value for each pixel among the subset of projections if the signal passing through the object of interest is expected to cause a decrease in a pixel value.

Abstract: A maxillofacial or cranial-facial surgical stabilizer comprising a head frame fully or partially surrounding the head of a patient at an angle running from ears to temple, and that is fixated to the skull of the patient by multiple screws and/or ear holders and screws. One or more flexible/locking arms are removably attached to the head frame for holding and positioning a plurality of interchangeable instruments or accessories. One flexible/locking arm is a medial/center arm accessorized with a dental arch mold. A method of using a head frame to position the pieces of bones during maxillofacial or cranio-facial surgery is also provided.

Abstract: Techniques for suppression of motion artifacts in medical imaging include obtaining projections at different times within a time interval from a medical imaging system operating on a subject. A stationary projection is determined for a first subset of the projections in which a signal source and detector array of the imaging system are in a first configuration relative to the subject. An image of the subject based on the stationary projection is displayed. For any subset, the stationary projection is a minimum value for each pixel among the subset of projections if a signal passing through a moving object of interest inside the subject is expected to cause an increase in a pixel value. Alternatively, the stationary projection is a maximum value for each pixel among the subset of projections if the signal passing through the object of interest is expected to cause a decrease in a pixel value.

Abstract: An apparatus for volumetric ultrasound imaging of a breast using different modes, including transmission, reflection and the speed of sound, which apparatus comprises a negatively pressurized breast imaging cup with integrated ultrasound transducers and an ultrasound coupling mechanism; an ultrasound system comprising the apparatus; and a method of imaging a breast in three dimensions without moving the ultrasound transducers.

Abstract: Preparing a plan to synchronize radiation delivery to a target in a patient with patient breathing phase and amplitude as the independent variable comprising (a) obtaining simultaneous data on patient breathing and target shape and location, (b) correlating the data and optimizing the correlation, (c) establishing optimal parameters of radiation delivery for each breathing phase/amplitude or for each target shape/location; and (d) synchronizing radiation delivery to a target in a patient with patient breathing comprising (a) positioning the patient, (b) monitoring actual breathing or the shape/location of the target, and (c) while monitoring, delivering radiation to the target according to a plan; and a system for controlling radiation delivery by a device to a target in a patient comprising (i) a processor, which receives and processes data on breathing or the shape/location of the target, and (ii) a controller, which controls radiation delivery to the target according to a plan, which synchronizes radiation

Abstract: A method of irradiating a target in a patient comprising directing a beam of radiation from an external source of radiation 24 at the target in the patient from numerous directions in a broad solid angle by longitudinally rotating the external source of radiation 24 around a central axis and simultaneously or sequentially, in either order, latitudinally rotating the external source of radiation 24; a globe gantry 21 comprising (i) a front opening ring 22 with its origin on the central axis of the globe gantry 21, (ii) at least one arc-shaped, gantry support arm 23, which has a front end and a rear end and is part of a circle, (iii) an external source of radiation 24, which is mounted on at least one arc-shaped, gantry support arm 23 and is movable along the gantry support arm to vary the latitude of the beam angle, (iv) a rear rotational axle 25 with an axis along the central axis of the globe gantry 21, (v) a support base 27, and (vi) a rear housing 26 comprising a source of power, mechanisms for moving comp

Abstract: A maxillofacial or cranial-facial surgical stabilizer comprising a head frame fully or partially surrounding the head of a patient at an angle running from ears to temple, and that is fixated to the skull of the patient by multiple screws and/or ear holders and screws. One or more flexible/locking arms are removably attached to the head frame for holding and positioning a plurality of interchangeable instruments or accessories. One flexible/locking arm is a medial/center arm accessorized with a dental arch mold. A method of using a head frame to position the pieces of bones during maxillofacial or cranio-facial surgery is also provided.

Abstract: A method of irradiating a target in a patient comprising directing a beam of radiation from an external source of radiation 24 at the target in the patient from numerous directions in a broad solid angle by longitudinally rotating the external source of radiation 24 around a central axis and simultaneously or sequentially, in either order, latitudinally rotating the external source of radiation 24; a globe gantry 21 comprising (i) a front opening ring 22 with its origin on the central axis of the globe gantry 21, (ii) at least one arc-shaped, gantry support arm 23, which has a front end and a rear end and is part of a circle, (iii) an external source of radiation 24, which is mounted on at least one arc-shaped, gantry support arm 23, (iv) a rear rotational axle 25 with an axis along the central axis of the globe gantry 21, (v) a support base 27, and (vi) a rear housing 26 comprising a source of power, mechanisms for moving components of the globe gantry 21, and controllers for controlling the movement of the

Abstract: A method of irradiating a target in a patient comprising directing a beam of radiation from an external source of radiation 24 at the target in the patient from numerous directions in a broad solid angle by longitudinally rotating the external source of radiation 24 around a central axis and simultaneously or sequentially, in either order, latitudinally rotating the external source of radiation 24; a globe gantry 21 comprising (i) a front opening ring 22 with its origin on the central axis of the globe gantry 21, (ii) at least one arc-shaped, gantry support arm 23, which has a front end and a rear end and is part of a circle, (iii) an external source of radiation 24, which is mounted on at least one arc-shaped, gantry support arm 23, (iv) a rear rotational axle 25 with an axis along the central axis of the globe gantry 21, (v) a support base 27, and (vi) a rear housing 26 comprising a source of power, mechanisms for moving components of the globe gantry 21, and controllers for controlling the movement of the

Abstract: Preparing a plan to synchronize radiation delivery to a target in a patient with patient breathing phase and amplitude as the independent variable comprising (a) obtaining simultaneous data on patient breathing and target shape and location, (b) correlating the data and optimizing the correlation, (c) establishing optimal parameters of radiation delivery for each breathing phase/amplitude or for each target shape/location; and (d) synchronizing radiation delivery to a target in a patient with patient breathing comprising (a) positioning the patient, (b) monitoring actual breathing or the shape/location of the target, and (c) while monitoring, delivering radiation to the target according to a plan; and a system for controlling radiation delivery by a device to a target in a patient comprising (i) a processor, which receives and processes data on breathing or the shape/location of the target, and (ii) a controller, which controls radiation delivery to the target according to a plan, which synchronizes radiation

Abstract: A method and device for accurately positioning patients for imaging and radiotherapy is disclosed. The device includes a support platform (such as a bed, a table, a couch, a chair, etc.) connected to a fixed base by at least two and preferably four offset supporting arms. The support arms are journaled into the support platform at passive-rotatable pivot joints and are journaled into the base at active-rotatable pivot points. The base contains actuators (manual or powered by motors, pneumatics or hydraulics) for articulating the support arms. The relative lengths of the support arms may be varied to create a pre-defined trajectory of the support platform, between a starting spatial position and orientation to an ending spatial position and orientation, and through a continuous range there between. This makes it possible to position a patient within a range from a low, standing up position to a high, forwarding, prone or supine position, or vice versa.

Abstract: An apparatus for volumetric ultrasound imaging of a breast using different modes, including transmission, reflection and the speed of sound, which apparatus comprises a negatively pressurized breast imaging cup with integrated ultrasound transducers and an ultrasound coupling mechanism; an ultrasound system comprising the apparatus; and a method of imaging a breast in three dimensions without moving the ultrasound transducers.

Abstract: A method of treating a cancerous region in a breast of a patient comprising (i) imaging the breast in a three-dimensional coordinate system, (ii) stereotactically determining the location of the cancerous region in the breast, (iii) optionally determining the volume of the entire cancerous region to be treated, and (iv) while maintaining the breast in a three-dimensional coordinate system that is identical to or corresponds with the three-dimensional coordinate system used in (i), noninvasively exposing the cancerous region of the breast of the patient to a cancer-treatment effective dose of radiation; and equipment for use in such a method.

Abstract: Techniques for background subtraction in computed tomography include determining voxels in a slice of interest in a three dimensional computed tomography scan of the interior of a body based on a first set of measurements of radiation transmitted through the body. Based on the first set of measurements, a first background image for radiation transmitted through the body in a first direction is determined without the effects of the voxels in the slice of interest. A current image is determined based on a different current measurement of radiation transmitted through the body in the first direction. A first difference is determined between the current image and the first background image. The result is a high contrast image in the slice of interest even from a single current projection image.

Abstract: A method of irradiating a target tissue in a patient comprising positioning the patient on a patient support system so that the target tissue in the patient is within irradiating distance of at least one source of a beam of radiation and moving the patient support system relative to the at least one source of a beam of radiation and, coordinately with movement of the patient support system, rotating the at least one source of radiation relative to the target tissue, which comprises and/or is adjacent to a non-target tissue, so that the center of rotation of the beam of radiation is placed at one or more desired locations within the target tissue, while simultaneously and/or sequentially irradiating the target tissue; a collimator; a method of making such a collimator; a system for irradiating a target tissue in a patient; and a method of planning irradiation of a target tissue in a patient.

Abstract: A method and device for accurately positioning patients for imaging and radiotherapy is disclosed. The device includes a support platform (such as a bed, a table, a couch, a chair, etc.) connected to a fixed base by at least two and preferably four offset supporting arms. The support arms are journaled into the support platform at passive-rotatable pivot joints and are journaled into the base at active-rotatable pivot points. The base contains actuators (manual or powered by motors, pneumatics or hydraulics) for articulating the support arms. The relative lengths of the support arms may be varied to create a pre-defined trajectory of the support platform, between a starting spatial position and orientation to an ending spatial position and orientation, and through a continuous range there between. This makes it possible to position a patient within a range from a low, standing up position to a high, forwarding, prone or supine position, or vice versa.

Abstract: A method of imaging a breast comprising (i) having a patient lie prone on a computer-controlled couch, which comprises a channel or left and right openings, and position the left or right breast of the patient in the channel or the left or right opening, respectively, and (ii) repeatedly imaging the breast using a scanning x-ray source while moving the couch down and up, such that the breast moves down and up in the field between the source of radiation and the detector, which method can further comprise constructing a three-dimensional image of the breast in its natural shape and analyzing the three-dimensional image of the breast; and a system for use in such a method.

Abstract: A method of irradiating a target tissue in a patient comprising positioning the patient on a patient support system so that the target tissue in the patient is within irradiating distance of at least one source of a beam of radiation and moving the patient support system relative to the at least one source of a beam of radiation and, coordinately with movement of the patient support system, rotating the at least one source of radiation relative to the target tissue, which comprises and/or is adjacent to a non-target tissue, so that the center of rotation of the beam of radiation is placed at one or more desired locations within the target tissue, while simultaneously and/or sequentially irradiating the target tissue; a collimator; a method of making such a collimator; a system for irradiating a target tissue in a patient; and a method of planning irradiation of a target tissue in a patient.

Abstract: A system and method for delivering radiation treatment to a moving target within a patient according to a preprogrammed treatment plan including determining a difference between a surrogate signal representing a physical characteristic associated with said patient's actual breathing pattern during radiation treatment delivery and a tracking signal representing a physical characteristic associated with said patient's expected breathing pattern during radiation treatment delivery, and regulating a speed of delivery of said radiation treatment based on said determined difference.

Abstract: A method of treating a cancerous region in a breast of a patient comprising (i) imaging the breast in a three-dimensional coordinate system, (ii) stereotactically determining the location of the cancerous region in the breast, (iii) optionally determining the volume of the entire cancerous region to be treated, and (iv) while maintaining the breast in a three-dimensional coordinate system that is identical to or corresponds with the three-dimensional coordinate system used in (i), noninvasively exposing the cancerous region of the breast of the patient to a cancer-treatment effective dose of radiation; and equipment for use in such a method.