Abstract: The present invention relates to the compound 2-ethyl-5,5-dimethyl-cyclohexanol, which can impart, modify and/or enhance one or more odours selected from the group consisting of minty, fresh tobacco leaf, cresol, horse and animalistic, mixtures comprising 2-ethyl-5,5-dimethyl-cyclohexanol, and a new method for producing the same, a fragrance composition comprising 2-ethyl-5,5-dimethyl-cyclohexanol, the use of 2-ethyl-5,5-dimethyl-cyclohexanol as a fragrance, particularly for imparting, modifying and/or enhancing one or more odours selected from the group consisting of minty, fresh tobacco leaf, cresol, horse and animalistic, a perfumed product comprising 2-ethyl-5,5-dimethyl-cyclohexanol, a method for perfuming such a product and a method for modifying an olfactory impression.

Abstract: The present disclosure is generally directed to orally consumable products, such as foodstuffs and beverages, containing rebaudioside E present in, e.g., about 5 ppm to about 100 ppm, and to methods for preparing such orally consumable products.

Abstract: Cigarettes are provided which contain a filtering system and flavorants encapsulated with polyvinyl acetate, wherein deactivation of a sorbent by the flavorant is reduced through the encapsulation of the flavorant within the polyvinyl acetate. A preferred flavorant is menthol. The encapsulated flavorants are prepared by mixing at least one flavorant with polyvinyl acetate and a solvent, such as ethanol, and forming the encapsulated flavorants. Methods of making cigarettes and smoking the articles are also provided.

Abstract: The present invention relates to new classes of odorous oximes and their ketone intermediates (odorants) which are useful as fragrance or flavor materials in particular in providing cassis, catty, tropical, green, coniferous, thuya, floral and/or fruity olfactory notes to perfume, aroma or deodorizing/masking compositions.

Abstract: In one aspect an aerosol-generating device comprising a smoking article and a heat source is described. The smoking article includes a smokable material and a cooling agent, the smokable material including a tobacco component. The heat source is disposed to heat, but not burn the smokable material in use. The cooling agent comprises a compound or a combination of compounds according to either of the following formulae, racemates, enantiomers and salts thereof (I, II).

Abstract: A smokeable material for inclusion in a smoking article, comprising tobacco coated with acacia gum, wherein the amount of acacia gum is at least 10% by weight of the tobacco.

Abstract: A (Z)-solanone has the steric formula of: or with the name of (S,Z)-5-isopropyl-8-methyl-6,8-diene-2-one or (R,Z)-5-isopropyl-8-methyl-6,8-diene-2-one. A process for the preparation of the (Z)-type solanone and the use thereof in flavoring of cigarette shred are further disclosed. The process includes the following steps: (1) reacting isopentanal and methyl vinyl ketone, under the action of a catalyst and a co-catalyst, to give (S)-2-isopropyl-5-carbonylhexanal or (R)-2-isopropyl-5-carbonylhexanal; (2) reacting the (S)-2-isopropyl-5-carbonylhexanal or the (R)-2-isopropyl-5-carbonylhexanal obtained in step (1) with (iodomethyl)triphenylphosphonium iodide, to give (S,Z)-7-iodo-5-isopropyl-6-ene-2-one or (R,Z)-7-iodo-5-isopropyl-6-ene-2-one; and (3) reacting the (S,Z)-7-iodo-5-isopropyl-6-ene-2-one or the (R,Z)-7-iodo-5-isopropyl-6-ene-2-one obtained in step (2) with pinacol isopropenylborate in the presence of a catalyst to give the (Z)-solanone.

Abstract: A method of preparing a whitened tobacco material is provided, the method including the steps of (i) extracting a tobacco material with an aqueous solution to give a tobacco pulp and a tobacco extract; (ii) treating the tobacco pulp with at least one of a caustic reagent and an oxidizing agent for a time and at a temperature sufficient to lighten the color of the tobacco pulp to give a whitened tobacco pulp; (iii) clarifying the tobacco extract to remove higher molecular weight components; and (iv) combining the whitened tobacco pulp with a clarified tobacco extract to form a whitened tobacco material. The whitened tobacco material can be isolated and incorporated into a smokeless tobacco product. The invention also provides a smokeless tobacco product incorporating a whitened tobacco material. The smokeless tobacco product may be a snus-type formulation contained within a sealed pouch.

Abstract: The present disclosure describes bee feed products formulated to increase consumption and methods of feeding such products to bees. Feeding methods involve feeding a bee feed composition on an ad libitum basis to bees where the composition contains an amount of a flavor agent that results in increased consumption. The flavor agent may be hydrated with a liquid to form a solution in some examples. The flavor agent may also be mixed directly with the bee feed composition high in protein.

Abstract: A liquid aerosol formulation for an electronic smoking article includes an aerosol former, water, nicotine, and an acid including tartaric acid. The acid is included in an amount sufficient to provide the liquid aerosol formulation with a pH ranging from about 4 to about 8.

Abstract: The present invention relates to the novel use of a carboxylate compound as a fragrance material.

Abstract: The present invention provides a compound represented by general formula (1). (In the formula, R1 represents an alkyl group having 2 to 9 carbon atoms, an alkenyl group having 2 to 9 carbon atoms, a cyclic alkyl group having 3 to 10 carbon atoms which may have a substituent, or a phenyl group which may have a substituent; R2 represents an alkyl group having 1 to 3 carbon atoms; R3 to R5 independently represent a hydrogen atom, or an alkyl group having 1 to 3 carbon atoms; R6 represents an alkyl group having 1 to 5 carbon atoms, an alkenyl group having 2 to 5 carbon atoms, a cyclic alkyl group having 3 to 10 carbon atoms which may have a substituent, or an alkoxy group having 1 to 5 carbon atoms; n represents 0 or 1; and the wavy line represents a cis form, a trans form or a mixture of a cis form and a trans form.

Abstract: The present invention relates to a mutant, non-naturally occurring or transgenic plant cell comprising: (i) at least one polynucleotide comprising, consisting or consisting essentially of a sequence encoding an isopropylmalate synthase and having at least 60% sequence identity to SEQ ID NO:1 or SEQ ID NO:10 or SEQ ID NO: 12 or SEQ ID NO:14; or (ii) a polypeptide encoded by said polynucleotide(s); or (iii) a polypeptide having at least 60% sequence identity to SEQ ID NO:2 or SEQ ID NO:11 or SEQ ID NO:13 or SEQ ID NO:15; or (iv) a construct, vector or expression vector comprising said polynucleotide sequence(s), optionally wherein said construct, vector or expression vector additionally comprises a promoter comprising, consisting or consisting essentially of the sequence set forth in SEQ ID NO:8 or a variant thereof with at least about 60% identity thereto or a trichome promoter.

Abstract: Disclosed are methods and compositions for preparing tobacco such that components of tobacco tar are reduced, while maintaining the total tar delivery of a composition or device containing tobacco treated with one or more natural tar diluents. Artificial tar diluents can also be used in combination with one more natural tar diluents. The tobacco compositions have decreased levels of tobacco specific nitrosamines and/or other components found in tar when the composition is smoked, while maintaining the total tar delivery of the smoking article, such as a cigarette, when using a tar diluent at a level sufficient to achieve desired taste qualities.

Abstract: The present discovery pertains generally to the field of therapeutic compounds. More specifically the present discovery pertains to certain di-isopropyl-phosphinoyl-alkanes as described herein, DIPA-1-5, DIPA-1-6, DIPA-1-7, DIPA-1-8, and DIPA-1-9, collectively referred to herein as “DIPA compounds”, that are useful, for example, in the treatment of disorders (e.g., diseases) including: sensory discomfort (e.g., caused by irritation, itch, or pain); a skin dysesthesia; dermatitis; ocular pain and discomfort; heat discomfort; heat stress; flushing and/or night sweats (vasomotor symptoms); post-operative hypothermia; post-anaesthetic shivering; fatigue; tiredness; depression; cognitive dysfunction; and to enhance cognitive function. The applicant has found that localized delivery of DIPA compounds to the upper eyelid and/or facial skin has an alerting and enhancement effect on behavior and can be used to give a cosmetic refreshing look, to mental alertness, to reduce fatigue, and to improve work output.

Abstract: Disclosed are compounds that block off-notes in consumables and methods of blocking off-notes in consumables including off-notes provided by sweeteners such as stevioside, swingle extract, glyccerhizin, perillartine, naringin dihydrochalcone, neohesperidine dihydrochalcone, mogroside V, rubusoside, rubus extract, and rebaudioside A, and artificial sweeteners such as aspartame, saccharin, acesulfame K (Acesulfame potassium), sucralose and cyclamate.

Abstract: A cigarette paper is disclosed that contains at least one burn additive the concentration c(x) of which varies along a direction x of the cigarette paper. For the position-dependent concentration c(x) over an interval of length L, for x over the interval [0,L], ƒ(x)??c?c(x)?ƒ(x)+?c. In this regard, 3 cm?L?11 cm, ƒ(x) is monotonic over the interval [0,L], but not a constant function over the entire interval, and ?c?1% by weight, preferably ?0.7% by weight and particularly preferably ?0.5% by weight, and especially preferably ?0.3% by weight and particularly preferably ?0.15% by weight and ?c>0% by weight, each with respect to the mass of the cigarette paper.

Abstract: The present invention relates to a novel method for synthesizing, without a solvent, N-alkyl-glycosyl(di)amine derivatives represented by the following general formula (I): The invention also concerns the use of N-alkyl-glycosyl(di)amine derivatives represented by the general formula (I), and N-alkyl-glycosyl(di)ammonium quaternary salts represented by the general formula (II) and N-alkyl-glycamine derivatives represented by the general formula (III) obtained from N-alkyl-glycosyl(di)amine derivatives represented by the general formula (I), as antibacterial and/or antifungal agents against phytopathogens.

Abstract: Provision of a TRPA1 activity inhibitor capable of reducing sensory irritation to skin or mucous membrane and an agent for reduction of sensory irritation for skin or mucous membrane. A TRPA1 inhibitor and an agent for reduction of sensory irritation for skin or mucous membrane comprising as an active ingredient a compound represented by the following formula (1) wherein R1 and R3 each independently represent a hydrogen atom or an alkyl group having 1 to 3 carbon atoms, R2 represents an alkyl group having 1 to 6 carbon atoms, R4 represents a hydrogen atom, a methyl group or an ethyl group, and a double line composed of a dotted line and a solid line represents a single bond or a double bond.

Abstract: The invention provides an smokeless tobacco composition adapted for oral use, the composition including a tobacco material and an effervescent material. The effervescent material includes an acid component and a base component, wherein the acid component includes a triprotic acid such as citric acid and at least one additional acid. The invention also provides a method for making a smokeless tobacco composition that involves first forming a granulation mixture, granulating the granulation mixture, and then blending the resulting granules with further blending components. Thereafter, the material can be formed into a predetermined shape, such as by compression or extrusion. The acid component of the effervescent material is divided into two portions, the first portion added to the granulation mixture and the remaining portion added during the blending step.

Abstract: The present discovery pertains generally to the field of therapeutic compounds. More specifically the present discovery pertains to certain di-alkyl-phosphinoyl-alkanes as described herein, DIPA-1-8 and DIPA-1-9, and 2-6 and 2-7 that are collectively referred to herein as “DAPA compounds”, that are useful in the treatment of disorders (e.g., diseases) including: sensory discomfort (e.g., caused by inflammation, irritation, itch, or pain) in the nasal cavity. The applicant has found that localized delivery of DAPA compounds with a swab to the Kiesselbach's area of the human nose will relieve the discomforts of rhinitis and other nasal cavity discomforts.

Abstract: According to an aspect of the present application, a composition for controlling a target pest comprises 0.1% to 4% isopropyl myristate, 0.1% to 15% thyme oil white, 0.1% to 2% geraniol, and at least one additional active ingredient selected from thymyl acetate, linalyl acetate, amyl butyrate, anise star oil, black seed oil, p-cymene, linalool, d-limonene, isopropyl myristate, lilac flower oil, methyl salicylate, alpha-pinene, piperonal, piperonyl alcohol, tetrahydrolinalool, thyme oil white, thyme oil red, thymol, vanillin, and wintergreen oil. The composition causes synergistic control of the target pest.

Abstract: The present invention is directed to novel fragrance compounds and their unexpected advantageous use in improving, enhancing or modifying a fragrance formulation through the addition of an olfactory acceptable amount of the compounds, wherein the compounds are represented by the following formula: an isomer or a mixture of isomers thereof, wherein one of R and R? represents hydrogen with the other representing a C1-C6 linear, branched, or cyclic alkyl, alkenyl, alkynyl or aromatic group; and one of the dashed lines represents a carbon-carbon single bond with the other representing a carbon-carbon double bond.

Abstract: The disclosure provides compounds useful as insect repellents and compositions comprising such repellents. The disclosure further provides insect traps and method for identifying ligands and cognates for biological molecules.

Abstract: The present invention concerns compounds of formula (I) in the form of any one of its stereoisomers or a mixture thereof, and wherein one dotted line represents a carbon-carbon single or double bond and the others a carbon-carbon single bond; each R, independently from each other, represents a hydrogen atom or a methyl or ethyl group provided that at least one of said R groups represents a methyl or ethyl group; and R1 represents a methyl or ethyl group; and their use in perfumery to impart odor notes of the woody type having cedar, ambery, patchouli and/or rooty aspect.

Abstract: The present invention provides a novel carboxylic acid ester compound useful as a fragrance component or a material for a compound fragrance and a method for producing the same, and provides a fragrance composition including the carboxylic acid ester compound. The present invention also provides an acyl fluorides of a 2,4-dimethyl-bicyclo[2.2.2]octane compound and the esters thereof, useful as the raw materials (inclusive of the intermediates of organic synthesis), for example, for the medicines, agricultural chemicals, fragrances, functional resins, optical functional materials and electronic functional materials. The carboxylic acid ester compound of the present invention is a compound represented by the general formula (1). (In the formula, one of R1 and R2 is a methyl group and the other of R1 and R2 is —COOR, and R is an alkyl group having 1 to 4 carbon atoms.

Abstract: A smoking composition for inclusion in a combustible smoking article includes a combustible organic material, such as tobacco and/or tobacco substitutes and at least one alkanoylated glycoside for enhancing the flavor of mainstream smoke. Optionally, dry hops extract can also be included in the smoking composition.

Abstract: The present invention relates to a mutant, non-naturally occurring or transgenic plant cell comprising: (i) at least one polynucleotide comprising, consisting or consisting essentially of a sequence encoding an isopropylmalate synthase and having at least 60% sequence identity to SEQ ID NO:1 or SEQ ID NO:10 or SEQ ID NO: 12 or SEQ ID NO:14; or (ii) a polypeptide encoded by said polynucleotide(s); or (iii) a polypeptide having at least 60% sequence identity to SEQ ID NO:2 or SEQ ID NO:11 or SEQ ID NO:13 or SEQ ID NO:15; or (iv) a construct, vector or expression vector comprising said polynucleotide sequence(s), optionally wherein said construct, vector or expression vector additionally comprises a promoter comprising, consisting or consisting essentially of the sequence set forth in SEQ ID NO:8 or a variant thereof with at least about 60% identity thereto or a trichome promoter.

Abstract: A smoking article (10, 20) comprises a flavour release segment (12). The flavour release segment (12) comprises a plug of fibrous material circumscribed by a substantially air impermeable wrapper and a plurality of solid menthol particles distributed within the plug of fibrous material. The fibrous material comprises randomly oriented fibres. Preferably the smoking article (10, 20) comprises a mouthpiece (4), wherein the mouthpiece (4) comprises the flavour release segment (12).

Abstract: Electrically heated cigarettes used in an electrical smoking system include a flavoring-release additive and sorbent effective to remove one or more gas-phase constituents of mainstream tobacco smoke. The flavoring-release additive includes gamma cyclodextrin and at least one flavoring. Flavoring is released in a cigarette upon the flavoring-release additive reaching at least a minimum temperature during smoking. The flavoring-release additive can have various forms including, for example, powder and films.

Abstract: An oral product includes a body that is wholly receivable in an oral cavity. The body includes a polymer matrix and one or more flavorants and/or active ingredients embedded in the polymer matrix. The polymer matrix can include a copolymer of ethylene and one or more vinyl monomers or zein. For example, the polymer can be ethylene-vinyl acetate copolymer and/or ethylene-vinyl alcohol copolymer. In some cases, the oral product can include tobacco and/or nicotine.

Abstract: A method of modulating the flavor of an orally-receivable product, such as a foodstuff, beverage, dentifrice or medicine, comprising the addition thereto of a flavor-modulating proportion of at least one compound of the formula I in which X is selected from CHOH, C?O, CH2—CO and CH?C(OH), Y is selected from C1-C7 linear and branched alkyl and CH2CH2OH, Z is selected from CH3 and a moiety of the formula II in which the wavy bond represents bond linking Z to X and R1 and R2 are selected from the possibilities (i) both hydrogen; (ii) independently OH and OCH3; and (iii) R1 and R2 together with their bonds to the phenyl ring form a ring of the formula —O—CH2—O—; such that, when Z is CH3, X is C?O and Y is CH2CH2OH.

Abstract: A smokeless tobacco product configured for insertion into the mouth of a user of the product is provided, the tobacco product including a water-permeable pouch containing a tobacco formulation, the tobacco formulation including a tobacco material and a plurality of microcapsules dispersed within the tobacco material, the plurality of microcapsules including an outer shell encapsulating an internal payload. The internal payload may include an additive such as water, flavorants, binders, colorants, pH adjusters, buffering agents, fillers, disintegration aids, humectants, antioxidants, oral care ingredients, preservatives, additives derived from herbal or botanical sources, and mixtures thereof. Microencapsulated flavorants include tobacco-containing flavorants, such as tobacco extracts or a particulate tobacco material, sweeteners (e.g., sweeteners containing neotame), and vanillin (optionally in a complexed form).

Abstract: Compositions are provided which contain immobilized flavorants for flavor delivery. In particular, smoking compositions are provided which contain flavorant ester salts of polycarboxylic acids.

Abstract: Compositions are provided which contain immobilized flavorants for flavor delivery. In particular, smoking compositions are provided which contain flavorant ester salts of polycarboxylic acids.

Abstract: A filter (4) for a smoking article (10, 20, 30) comprises a flavour release segment (14) including a plurality of flavour granules. The flavour granules comprise a porous support material, a liquid flavourant, particles of plant material, and at least one binder. The plant material preferably comprises herbaceous material, more preferably herb leaf and most preferably peppermint leaf. The liquid flavourant preferably comprises at least one of: an essential oil, such as peppermint oil or spearmint oil; and natural or synthetic menthol.

Abstract: A process for producing a coated filter plug for a smoking article including: (a) incorporating an additive to a porous filter plug, thereby obtaining an impregnated filter plug; (b) coating a surface of the impregnated filter plug with a cross-linkable polymer material; and (c) cross-linking the cross-linkable polymer material, to form a cross-linked, breakable coating substantially enclosing the impregnated filter plug. The process may further include at least partially coating the impregnated filter plug with a cross-linking agent prior to, or subsequent to, coating with the cross-linkable polymer material.

Abstract: A cigar comprises a mouth end; a tobacco section comprising tobacco material; at least one sweetener dispersed throughout the tobacco section; and/or a flavor potentiator and/or a taste modifier on an outer surface of the mouth end for enhancing the sweet taste of the cigar.

Abstract: The present invention relates to the field of improving the flavour of foodstuffs, beverages, tobacco products, pharmaceutics and oral care products. More particularly, the present invention provides flavour modulating substances selected from the group represented by formula (I): and edible salts thereof and edible esters thereof, which can advantageously be used for modulating the flavour of foodstuffs, beverages, tobacco products, pharmaceutics and oral care products. These flavour modulating substances can be used to impart desirable taste attributes in a wide variety of applications and products. In addition, the present flavour modulating substances are capable of modulating the taste and/or aroma impact of other, flavour imparting, substances contained within these same products, thereby improving the overall flavour quality of these products.

Abstract: A smokable composition includes (a) a smokable material; and (b) a supramolecular assembly. The supramolecular assembly comprises a flavorant and at least one selected from the group consisting of O,O?-dibenzoyl-(2R,3R)-tartaric acid, a hydrate thereof or a salt thereof, and ditoluoyl-(2R,3R)-tartaric acid, a hydrate thereof or a salt thereof. In addition, a smoking article comprises a rod of tobacco or tobacco substitute, optionally a filter attached to the rod, and the supramolecular assembly, as menthol-release agent.

Abstract: A cigarette includes a tobacco rod in which a tobacco filler containing cut tobacco is wrapped with a cigarette paper, the tobacco rod being constituted by a distal end portion, a proximal end portion and a center portion, and a filter, the proximal end portion being connected to the filter. The distal end portion includes a volatile flavor-containing material incorporated in a gel of a polysaccharide, the center portion includes or does not include the volatile flavor-containing material, the proximal end portion includes or does not include the volatile flavor-containing material, and there is no case where both the center portion and the proximal end portion include the volatile flavor-containing material.

Abstract: There is provided a tobacco smoke filter (1) or filter element comprising: a rod (2) of a tobacco smoke filtering material; a continuous extruded element (7) extending longitudinally of the rod (2); and a flavouring agent.

Abstract: Cigarettes are provided which contain a filtering system and flavorants encapsulated with polyvinyl acetate, wherein deactivation of a sorbent by the flavorant is reduced through the encapsulation of the flavorant within the polyvinyl acetate. A preferred flavorant is menthol. The encapsulated flavorants are prepared by mixing at least one flavorant with polyvinyl acetate and a solvent, such as ethanol, and forming the encapsulated flavorants. Methods of making cigarettes and smoking the articles are also provided.

Abstract: A tobacco smoke filter or filter element comprising: a tobacco smoke filtering material including paper; and a flavour enhancing additive.

Abstract: Compositions are provided which contain immobilized flavorants, in the form of supramolecular complexes of flavorant compounds, for flavor delivery. One embodiment relates to the flavorant supramolecular complexes themselves; Other embodiments relate compositions which contain the flavorant supramolecular complexes and a substrate. In particular embodiments, the substrate is smokable, but in other embodiments may be non-smokable or comestible.

Abstract: Disclosed is a smoking article containing a rod containing a smokable composition, an optional wrapper for the rod, and at least one polymer or oligomer comprising monomer units of a polycarboxylic acid ester disposed on or in the rod, the wrapper, or both. The polycarboxylic acid ester contains an acid moiety having at least two carboxylic groups, and at least two alcohol moieties independently selected from those corresponding to a cycloalkyl alcohol or an aryl alcohol. The cycloalkyl alcohol or aryl alcohol is a flavorant, or chemesthetic agent, or both. In addition, a method for the controlled release of these flavorant or chemesthetic agents is described, which comprises pyrolyzing at least one polymer or oligomer.

Abstract: A smokeless tobacco product configured for insertion into the mouth of a user of the product is provided, the tobacco product including a water-permeable pouch containing a tobacco formulation, the tobacco formulation including a tobacco material and a plurality of microcapsules dispersed within the tobacco material, the plurality of microcapsules including an outer shell encapsulating an internal payload. The internal payload may include an additive such as water, flavorants, binders, colorants, pH adjusters, buffering agents, fillers, disintegration aids, humectants, antioxidants, oral care ingredients, preservatives, additives derived from herbal or botanical sources, and mixtures thereof. Microencapsulated flavorants include tobacco-containing flavorants, such as tobacco extracts or a particulate tobacco material, sweeteners (e.g., sweeteners containing neotame), and vanillin (optionally in a complexed form).

Abstract: The invention provides a method of imparting flavor to smokeless tobacco, and the flavored smokeless tobacco produced therefrom.

Abstract: The present invention relates to a smoking article comprising two layers of wrapper material, the outer wrapper having an air permeability of at least 200 C.U. and having a greater permeability than the inner wrapper. Encapsulated flavour is held between the inner and outer wrappers. The encapsulation technique is dependent upon the flavour to be encapsulated and the sidestream to mainstream flavour delivery ratio required. Sidestream smoke may be altered without altering the mainstream smoke, thereby altering room odors.

Abstract: A nontoxic, tobacco-less and flavored material for smoking, and a method of making the same. In one aspect, the invention is a tobacco-less material for smoking comprising: a shredded cellulosic paper having a weight; and a mixture of a humectant and a flavoring agent, the mixture having a weight and absorbed into the shredded cellulosic paper.