Abstract: A method for precision thermal measurement and control, especially for bioreactors, as well as the correction of temperature sensitive probes such as pH and dissolved oxygen. Typical control requirements are ±0.1° C. The thermal measurement circuit converts a sensor output to a high level voltage or current with great accuracy and provides noise immunity and sensor isolation. While digital outputs from sensor converters can have the greatest noise immunity, the noise associated with digital circuitry may contaminate low level sensor signals so in many cases an analog sensor converter is preferred because of low noise generation, especially if the converter is near the sensor. The circuit is low cost, reliable, generates minimal heat is immune to, and does not generate noise, and requires minimal calibration effort.

Abstract: The invention provides a method for measuring the heat release rate of a flame retardardant compound in a microscale combustion calorimeter.

Abstract: A modulated differential scanning calorimeter that accounts for heat flow due to evaporative solvent loss. The calorimeter modulates the temperature applied to a sample and a reference to determine the amount of heat flow that is due to evaporation. By calculating the amount of heat flow due to evaporation, the user can determine how much of the heat flow of any given well is due to the process of interest as opposed to evaporation.

Abstract: A sensor for a heat flux differential scanning calorimeter in which the differential temperatures are measured between locations external to the regions of heat exchange between the sensor and sample containers. The measured differential temperatures respond to the magnitude of the heat flow rate between the sensor and the sample and reference containers and are rendered insensitive to variations in the magnitude and distribution of thermal contact resistance between the sensor and the containers.