Food Or Edible As Carrier For Pharmaceutical Patents (Class 424/439)
  • Patent number: 11896016
    Abstract: Methods and products related to a cereal product having a water activity of about 0.4 or more and an SAG content of greater than about 15 g per 100 g of cereal product.
    Type: Grant
    Filed: October 3, 2014
    Date of Patent: February 13, 2024
    Assignee: GENERALE BISCUIT
    Inventors: Monika Okoniewska, Isabel Moreira De Almeida, Lélia Notardonato, Jérôme Clément, Edward C. Coleman, Pierre Berny, Pierre-Marie Faye, Didier Harichane
  • Patent number: 11878007
    Abstract: In various embodiments of the present disclosure, compositions exhibiting metabolism boosting effect are described. In various examples, compositions comprise a synergistic combination of at least one plant, root, seed, or fruit material, or extract thereof, or bioactive therefrom; at least one vitamin, essential trace mineral, or enzyme or vitamin cofactor; at least one amino acid; and at least one antioxidant. In various aspects, metabolism enhancing compositions are formulated as loose powders filled into capsules as orally administered dietary supplements. In various embodiments, compositions of the present disclosure are used to treat metabolic syndrome in subjects expressing symptoms thereof.
    Type: Grant
    Filed: August 10, 2022
    Date of Patent: January 23, 2024
    Assignee: RED MOUNTAIN MED SPA, LLC
    Inventor: Suzanne Bentz
  • Patent number: 11825856
    Abstract: Provided is a composition for preventing or ameliorating a functional gastrointestinal disorder whose active ingredient is Bifidobacterium breve MCC1274 (FERM BP-11175). A composition for preventing or ameliorating a functional gastrointestinal disorder in the present technology can prevent or improve constipation or frequent bowel movements, regulate the number of bowel movements, improve stool quality, prevent or improve constipation, prevent or ameliorate bloating, or prevent or improve abdominal discomfort. Disclosed is a composition for preventing or ameliorating a functional gastrointestinal disorder accompanied by anxiety disorder. A composition for preventing or ameliorating a functional gastrointestinal disorder in the present technology can be used in a pharmaceutical composition or in a food or beverage composition.
    Type: Grant
    Filed: March 12, 2019
    Date of Patent: November 28, 2023
    Assignee: Morinaga Milk Industry Co., Ltd.
    Inventors: Mai Murata, Junichi Minami, Hazuki Maehata
  • Patent number: 11806315
    Abstract: A pet food composition specifically formulated for a small dog can include a combination of specific amino acids and probiotics to maintain or increase absorption of amino acids. Methods of increasing absorption of amino acids are also provided.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: November 7, 2023
    Assignee: SOCIÉTÉ DES PRODUITS NESTLÉ S.A.
    Inventors: Rondo P Middleton, Gail Czarnecki-Maulden, Christina Petzinger Germain, Alison Beloshapka, James Kaput, Steven S Hannah
  • Patent number: 11758928
    Abstract: A specific type of organ health marker in a companion animal can be improved by adjusting the diet of the animal to increase the amount of a compound which positively or negatively modulates the specific type of organ health marker or adjusting the diet of the animal to decrease the amount of a compound which positively or negatively modulates the specific type of organ health marker. The specific type of organ health marker can be one or more of phosphorus, alkaline phosphatase, aspartate aminotransferase, or gamma-glutamyltransferase.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: September 19, 2023
    Assignee: SOCIÉTÉ DES PRODUITS NESTLÉ S.A.
    Inventors: Rondo P Middleton, Brian M Zanghi, Serge Andre Dominique Rezzi, Steven S Hannah
  • Patent number: 11707077
    Abstract: Provided are engineered meat products formed as a plurality of at least partially fused layers, wherein each layer comprises at least partially fused multicellular bodies comprising non-human myocytes and wherein the engineered meat is comestible. Also provided are multicellular bodies comprising a plurality of non-human myocytes that are adhered and/or cohered to one another; wherein the multicellular bodies are arranged adjacently on a nutrient-permeable support substrate and maintained in culture to allow the multicellular bodies to at least partially fuse to form a substantially planar layer for use in formation of engineered meat. Further described herein are methods of forming engineered meat utilizing said layers.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: July 25, 2023
    Assignee: The Curators of the University of Missouri
    Inventors: Gabor Forgacs, Francoise Marga, Karoly Robert Jakab
  • Patent number: 11666076
    Abstract: The invention provides a method for providing a non-uniform pigment distribution in a first plant part (110) of a pigment generating plant (100), which accumulates pigment upon exposure by light, during indoor cultivation of said plant (100), wherein the first plant part (110) comprises a second plant part (120) and a third plant part (130), the method comprising subjecting in a first lighting stage at least the first plant part (110) to first light conditions that inhibit or prevent pigment accumulation in said first plant part (110), and subsequently subjecting in a second lighting stage the second plant part (120) of said first plant part (110) to second light conditions that promote pigment accumulation in said second plant part (120) while subjecting the third plant part (130) of said first plant part (110) to third light conditions that inhibit or prevent pigment accumulation in said third plant part (130).
    Type: Grant
    Filed: May 9, 2017
    Date of Patent: June 6, 2023
    Assignee: SIGNIFY HOLDING B.V.
    Inventors: Céline Catherine Sarah Nicole, Marcellinus Petrus Carolus Michael Krijn, Gus Van Der Feltz
  • Patent number: 11612587
    Abstract: The present invention relates to a pharmaceutical composition for preventing or treating hair loss, a health functional food composition or a cosmetic composition, including a specific compound or a pharmaceutically acceptable salt thereof as an active ingredient, wherein the compound exhibits an excellent hair growth recovery effect in hair follicle tissues in which hair growth is inhibited without cytotoxicity, and thus hair loss can be more effectively prevented, improved, or treated.
    Type: Grant
    Filed: February 19, 2019
    Date of Patent: March 28, 2023
    Assignee: KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Young Kwan Sung, Soon Sun Bak
  • Patent number: 11602510
    Abstract: The invention relates to an agent for use in the prophylaxis or treatment of dyslipidemia, in particular for the treatment of excessive/elevated LDL levels, containing propionic acid or a physiologically acceptable propionic acid derivative.
    Type: Grant
    Filed: March 9, 2018
    Date of Patent: March 14, 2023
    Assignee: Flexopharm Brain GMBH & Co. KG
    Inventor: Aiden Haghikia
  • Patent number: 11590207
    Abstract: The present invention relates to a pharmaceutical composition comprising at least one controlled-release PTH compound or a pharmaceutically acceptable salt, hydrate or solvate thereof, for use in the treatment, control, delay or prevention of a condition that can be treated, controlled, delayed or prevented with PTH, pharmaceutical composition comprising at least one controlled-release PTH compound or a pharmaceutically acceptable salt, hydrate or solvate thereof, for use in the treatment, control, delay or prevention of a condition that can be treated, controlled, delayed or prevented with PTH, wherein said pharmaceutical composition is administered no more frequently than once every 24 hours with a dosage of the controlled-release PTH compound that corresponds to no more than 70% of the molar equivalent dose of PTH 1-84 administered every 24 hours required to maintain serum calcium within normal levels over said 24 hour period in humans.
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: February 28, 2023
    Assignee: ASCENDIS PHARMA BONE DISEASES A/S
    Inventors: Lars Holten-Andersen, Kennett Sprogøe, David Brian Karpf
  • Patent number: 11576403
    Abstract: The invention provides compositions and methods for metabolic health in an animal comprising administering a non-ketogenic composition to the animal, wherein the non-ketogenic composition comprises about 5% to about 25% carbohydrates, about 30% to about 60% protein, and about 10% to about 40% fat. Additionally, the composition can have a protein to carbohydrate ratio of at least 2:1.
    Type: Grant
    Filed: December 6, 2019
    Date of Patent: February 14, 2023
    Assignee: Societe des Produits Nestle S.A.
    Inventors: Yuanlong Pan, Hui Xu
  • Patent number: 11547713
    Abstract: The present invention provides a composition comprising HMB and Vitamin D. Methods of administering HMB and Vitamin D to an animal are also described. Vitamin D and HMB are administered to increase muscle mass, strength, and functionality. The combination of Vitamin D and HMB together has a synergistic effect, which results in a surprising and unexpected level of improvement in muscle mass, strength and functionality.
    Type: Grant
    Filed: June 10, 2020
    Date of Patent: January 10, 2023
    Assignee: Metabolic Technologies, LLC
    Inventors: John Rathmacher, John Fuller, Jr., Shawn Baier, Steve Nissen, Naji Abumrad
  • Patent number: 11540550
    Abstract: A method for treating autoimmune and/or inflammatory diseases includes a step of identifying a subject having a gastrointestinal autoimmune/inflammatory disease. A fasting mimicking diet (FMD) is administered to the subject for a first time period.
    Type: Grant
    Filed: May 11, 2017
    Date of Patent: January 3, 2023
    Assignee: University of Southern California
    Inventors: Valter D. Longo, In Young Choi
  • Patent number: 11533944
    Abstract: A smokeless tobacco product is provided that includes a tobacco material in the form of a tobacco extract, a particulate tobacco material, or a combination thereof. In some embodiments, the smokeless tobacco product is substantially translucent. Methods for making and using the smokeless tobacco product are also provided. The smokeless tobacco product can include isomalt, maltitol syrup, particulate tobacco, and a translucent tobacco extract prepared by ultrafiltration.
    Type: Grant
    Filed: March 19, 2020
    Date of Patent: December 27, 2022
    Assignee: R.J. Reynolds Tobacco Company
    Inventor: Darrell Eugene Holton, Jr.
  • Patent number: 11497779
    Abstract: The present invention concerns novel Lactobacillus plantarum strains capable of promoting the growth of a subject, and more particularly the juvenile or prenatal growth of farm animals, and their uses as probiotics.
    Type: Grant
    Filed: August 17, 2018
    Date of Patent: November 15, 2022
    Assignees: ECOLE NORMALE SUPERIEURE DE LYON, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE CLAUDE BERNARD LYON 1
    Inventors: François Leulier, Maria Elena Martino
  • Patent number: 11484550
    Abstract: A pharmaceutical composition of the present invention is used for improving health, cure abnormalities and degenerative disease; achieve anti-aging effect of therapy and therapeutic effect on mammals. The pharmaceutical composition includes a pharmaceutical carrier and an isotope selective ingredient including at least one of a chemical element and a chemical compound containing the chemical element whereby isotope distribution in the at least one of the chemical element and the chemical compound containing the chemical element is different from natural distribution of at least one of isotopes wherein the part of selected isotope of the chemical element ranges from 0 to 100%. A method of the present invention uses the inventive pharmaceutical composition to improve health, cure abnormalities and degenerative disease and achieve therapeutic effect on mammals.
    Type: Grant
    Filed: December 7, 2020
    Date of Patent: November 1, 2022
    Assignee: VECTOR VITALE IP LLC
    Inventors: Peter Novak, Maxim Temnikov, Oleksandr Balakin
  • Patent number: 11471479
    Abstract: Concentrated, low-viscosity, low-volume liquid pharmaceutical formulations of polysaccharides and nucleic acids have been developed. Such formulations can be rapidly and conveniently administered by subcutaneous or intramuscular injection, rather than by lengthy intravenous infusion. These formulations include low-molecular-weight and/or high-molecular-weight polysaccharides and nucleic acids, and viscosity-lowering agents.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: October 18, 2022
    Assignee: Eagle Biologics, Inc.
    Inventors: Alyssa M. Larson, Kevin Love, Alisha K. Weight, Alan Crane, Robert S. Langer, Alexander M. Klibanov
  • Patent number: 11446246
    Abstract: Suspensions of metronidazole or baclofen and/or salts or ester derivative thereof, such as metronidazole benzoate, are disclosed. The suspension my include metronidazole or baclofen, and/or a salt or ester derivative thereof a hydrocolloid stabilizer, simethicone emulsion, a buffer, such as sodium citrate, (dihydrate), a preservative, a thickening agent, a sweetener, and water.
    Type: Grant
    Filed: April 21, 2022
    Date of Patent: September 20, 2022
    Assignee: Azurity Pharmaceuticals, Inc.
    Inventors: Ken Fallin, Zeus Pendon, Priya Capila, Neal Muni
  • Patent number: 11437134
    Abstract: To help consumers around the world reduce the confusion and complexity of choosing among thousands of wellness products that are effective for their particular medical conditions and/or wellness goals, the present inventor, devised one or more exemplary systems, methods, software, and data structures for recommending products, such as health, fitness, and nutritional products, to consumers. One exemplary system receives user profile information, such as gender, age, medical condition(s), wellness goal(s), biometric data, allergies and sensitivities, and/or nutrition information, and recommends products based on the consumer profiles and product ingredient efficacy and/or contraindications for the medical conditions and/or wellness goals. The system recommends the most scientifically effective products for a particular consumer, while accounting for contraindications thereby reducing risk potentially harmful products.
    Type: Grant
    Filed: September 27, 2012
    Date of Patent: September 6, 2022
    Assignee: MyFormulary LLC
    Inventor: Adam Gyles Southam
  • Patent number: 11433030
    Abstract: A dosage form with a first portion and a second portion. The first portion can be an immediate release portion and can comprise a pain reliever, which can be naproxen or naproxen sodium. The second portion can be an extended release portion and can comprise pseudoephedrine or a pharmaceutically acceptable salt thereof and/or dextromethorphan or a pharmaceutically acceptable salt thereof. The dosage form can optionally comprise a stabilizing agent. The dosage form can be adapted to maintain a therapeutically effective amount of pain reliever, pseudoephedrine, or a pharmaceutically acceptable salt thereof, and/or dextromethorphan, or a pharmaceutically acceptable salt thereof, for at least eight hours.
    Type: Grant
    Filed: December 16, 2019
    Date of Patent: September 6, 2022
    Assignee: The Procter & Gamble Company
    Inventors: Mark Edward Stella, John Richard Entwisle, Baltej Ludher, Jonathan E. Clark, Daren K. Anness, Guhan Balan, Andrew Nicholas Carr
  • Patent number: 11419848
    Abstract: The present invention relates to a composition for the protection, treatment and repair of cartilage in humans and animal joints. The composition contains a combination of unsaponifiable lipids together with one or more of polyphenols and/or catechins. The composition or kit may contain avocado:soybean unsaponifiables (ASU) and green tea.
    Type: Grant
    Filed: August 19, 2020
    Date of Patent: August 23, 2022
    Assignee: NUTRAMAX LABORATORIES, INC.
    Inventors: Todd R. Henderson, Louis Lippiello, Charles Filburn, David Griffin
  • Patent number: 11413238
    Abstract: Storage stable sterile ready-to-administer formulations comprising N-acetylcysteine are presented with desirable stability characteristics. In preferred aspects, formulations comprise low quantities of one or more chelating agents, contain N-acetylcysteine at a concentration of 25 mg/mL or 50 mg/mL, and are packaged in a suitable format, such as a polymeric bag with a metalized overwrap and a non-contact oxygen scavenger.
    Type: Grant
    Filed: February 17, 2021
    Date of Patent: August 16, 2022
    Assignee: ENDO VENTURES LIMITED
    Inventors: Ronald Domalaon, Jinjiang Li, Tushar Hingorani, Kumaresh Soppimath
  • Patent number: 11400058
    Abstract: Disclosed herein are formulations suitable for parenteral administration of certain hydrophobic active agents such as Coenzyme Q10. Methods of preparing the same and methods of treatment of oncological disorders using the same are also provided herein. The formulations comprise an aqueous solution; a hydrophobic active agent dispersed to form a colloidal nano-dispersion of particles; and at least one of a dispersion stabilizing agent and an opsonization reducer wherein the colloidal nano-dispersion of the active agent is dispersed into nano-dispersion particles having a mean size of less than 200-nm. Methods of preparing the parenteral formulations comprise dispersing the hydrophobic active agent by high pressure homogenization by (1) adding hydrophobic active agent to a 65° C. bath of water and mixing to form a hydrophobic active agent/water mixture; (2) adding a dispersion stabilizing agent to the hydrophobic active agent/water mixture and mix at 65° C.
    Type: Grant
    Filed: March 11, 2011
    Date of Patent: August 2, 2022
    Assignee: Berg LLC
    Inventors: Niven Rajin Narain, John Patrick McCook
  • Patent number: 11382850
    Abstract: The invention provides compositions and methods for topically inhibiting, reducing or preventing growth or biofilm formation of caries-, gingivitis- and/or halitosis-causing bacteria. The composition includes at least about 0.005% (w/v) of tea polyphenols, a pH modulating agent for maintaining a pH of the composition above about 6.5, and at least about 1% (w/v) of a 3-carbon to a 24-carbon sugar alcohol. Also provided are food products or supplements incorporating such compositions.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: July 12, 2022
    Assignee: DoseBiome Inc.
    Inventors: Ted Jin, Mizue Naito
  • Patent number: 11364217
    Abstract: A composition useful for promoting a desired oral microbiota to treat an allergy related respiratory condition in a subject in need of such treatment, the composition including an amino acid containing ingredient including individual molecules of L-arginine; the composition in a configuration to be maintained within the oral cavity for a period of at least about 30 seconds to about an hour, the desired oral microbiota including Veillonella and Streptococcus.
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: June 21, 2022
    Assignee: Knoze Jr. Corporation
    Inventor: Shunsheng Han
  • Patent number: 11364255
    Abstract: Compositions including herbal extracts, such as a Vitex negundo extract, a Cardiospermum halicacabum extract, and a Bambusa arundinacea extract, and methods using such compositions are disclosed. For example, compositions and methods may be used to improve joint health.
    Type: Grant
    Filed: July 1, 2020
    Date of Patent: June 21, 2022
    Assignee: KARALLIEF, INC.
    Inventor: Krishna Rajendran
  • Patent number: 11367526
    Abstract: Medical devices and related augmented reality systems and methods are provided. A method of providing guidance to a patient using an electronic device having an imaging device associated therewith involves analyzing one or more images captured by the imaging device to identify image content indicative of a potential activity for the patient, determining, by a control system associated with the electronic device, one or more attributes for the potential activity, determining, by the control system, a predicted physiological response by the patient to the potential activity based at least in part on the one or more attributes, and providing, on a display associated with the electronic device, an augmented reality graphical user interface including a graphical indication influenced by the predicted physiological response.
    Type: Grant
    Filed: May 3, 2019
    Date of Patent: June 21, 2022
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Chia-Hung Chiu, Rebecca K. Gottlieb, Carol A. Jerome, Kenny J. Long
  • Patent number: 11364478
    Abstract: A method of encapsulating content with calcium alginate membrane to form a capsule. The method includes embedding sodium alginate into a traditional gelatin ribbon used in gelatin encapsulation, adding calcium to a fill material, encapsulating the fill material, and then denaturing the gelatin in the shell. An exemplary use of this method is to form throwable paintballs; however, other products could be formed using this process. A paintball formed by this process is also disclosed.
    Type: Grant
    Filed: May 15, 2020
    Date of Patent: June 21, 2022
    Assignee: Mezzimatic, LLC
    Inventor: Briana Gardell
  • Patent number: 11357247
    Abstract: An eggless mayo is provided that is heat stable or that is heat stable as well as freeze-thaw stable and that is all natural. In addition a mayonnaise composition is provided that has increased heat stability as well as freeze-thaw stability. A low-salt version of the eggless mayo is provided as well as compositions for various butters and creams that have enhanced heat stability as well as freeze-thaw stability.
    Type: Grant
    Filed: March 3, 2016
    Date of Patent: June 14, 2022
    Assignee: Texas Tech University System
    Inventor: Richard S. Meyer
  • Patent number: 11337450
    Abstract: UHT treated liquid nutritional compositions are provided having a high caloric content of around 2.0 kcal/ml and higher, a savoury taste and comprising protein, carbohydrate and fat components. The nutritional compositions are for use in the treatment of patients having high energy needs.
    Type: Grant
    Filed: September 22, 2017
    Date of Patent: May 24, 2022
    Assignee: FRESENIUS KABI DEUTSCHLAND GMBH
    Inventors: Susanne Wiegand, Katy Becker, Martin Ammann, Jose Maria Mainou-Sierra
  • Patent number: 11331329
    Abstract: The invention provides compositions and methods for utilizing oligosaccharides, such as isolated human milk oligosaccharides, to attenuate a respiratory pathogen infection and/or to promote recovery from a respiratory pathogen infection in the respiratory system and/or the GI tract of a subject.
    Type: Grant
    Filed: May 13, 2021
    Date of Patent: May 17, 2022
    Assignee: Glycosyn LLC
    Inventors: Ardythe L. Morrow, David S. Newburg, John M. McCoy
  • Patent number: 11318171
    Abstract: Methods and egg yolk powder containing compositions for improving skeletal muscle protein fractional synthetic rate (FSR) in mammals and inhibiting or reversing sarcopenia are provided.
    Type: Grant
    Filed: May 18, 2020
    Date of Patent: May 3, 2022
    Assignee: MYOS CORP.
    Inventors: Joseph Mannello, Neerav D. Padliya, Maghsoud Dariani
  • Patent number: 11298332
    Abstract: This disclosure provides a dry powder formulation of free amino acids with an acceptable and even good taste profile.
    Type: Grant
    Filed: June 19, 2019
    Date of Patent: April 12, 2022
    Assignee: AXCELLA HEALTH INC.
    Inventors: Thomas Hanlon, Andrew M. Wood
  • Patent number: 11291683
    Abstract: Compositions for oral administration and processes of preparing the same are described. In particular, compositions in the form of bilayer tablets including B vitamins for modified delivery are described. The bilayer multi-B vitamin tablets offer immediate release of a first set of B vitamins, such as riboflavin (B2) and cyanocobalamin (B12) followed by controlled release of a second set of B vitamins, such as folic acid, biotin, niacinamide (B3), pyridoxine (B6), pantothenic acid (B5) and thiamine (B1).
    Type: Grant
    Filed: March 28, 2017
    Date of Patent: April 5, 2022
    Assignee: ACCESS BUSINESS GROUP INTERNATIONAL LLC
    Inventors: David S. Chang, Dawna Venzon, Shilpa Raut, Allí Klosner, Janjira Intra, Edward S. Kahler
  • Patent number: 11291628
    Abstract: A chewable pharmaceutical product comprises a matrix comprising: a binder, a bulking agent, a lubricant, a humectant, an emulsifier, and optionally a flavoring, wherein the binder comprises one or more maltitol syrups, which are present in the pharmaceutical product in an amount in the range of 60-70% by weight; and colesevelam hydrochloride.
    Type: Grant
    Filed: July 21, 2016
    Date of Patent: April 5, 2022
    Assignee: Cosette Pharmaceuticals, Inc.
    Inventor: Tommy L. Chau
  • Patent number: 11285101
    Abstract: A soft chewable pharmaceutical product for delivery of a pharmaceutically acceptable active ingredient to an animal comprising pamoic acid or a pharmaceutically acceptable salt and a process for the manufacture of such soft chewable pharmaceutical product.
    Type: Grant
    Filed: March 8, 2019
    Date of Patent: March 29, 2022
    Assignee: Intervet Inc.
    Inventors: Susi Alteheld, Stefan Fuchs, Carina Hang, Jürgen Lutz
  • Patent number: 11278566
    Abstract: The present invention relates to an agent comprising anion-exchange groups that are suitable for adsorbing bacterial lipopolysaccharides (LPS) and/or lipoteichoic acids (LTA), for use in the prevention and/or treatment of inflammatory conditions and/or diseases of the oral cavity or in the vaginal region. The present invention also relates to a pharmaceutical composition that comprises an agent of this kind and can adhere to mucosa.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: March 22, 2022
    Inventor: Dietrich Seidel
  • Patent number: 11266701
    Abstract: The present invention provides a therapeutic composition comprising a synergistic combination of caffeine, Ginkgo biloba, and ?-phenylethylamine (PEA) or its salt. The invention is also directed to oral dosage forms containing said composition, and to a method of treatment of a psychological, psychiatric, behavioral and/or neurodevelopmental disorder comprising the administration of said compositions and dosage forms to a patient in need thereof.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: March 8, 2022
    Assignee: TRINUTRA LTD.
    Inventors: Itschak Lamensdorf, Yoram Sela, Mor Zeilkha
  • Patent number: 11246829
    Abstract: Residence structures, systems, and related methods are generally provided. Certain embodiments comprise administering (e.g., orally) a residence structure to a subject (e.g., a patient) such that the residence structure is retained at a location internal to the subject for a particular amount of time (e.g., at least about 24 hours) before being released. The residence structure may be, in some cases, a gastric residence structure. In some embodiments, the structures and systems described herein comprise one or more materials configured for high levels of active substances (e.g., a therapeutic agent) loading, high active substance and/or structure stability in acidic environments, mechanical flexibility and strength in an internal orifice (e.g., gastric cavity), easy passage through the GI tract until delivery to at a desired internal orifice (e.g., gastric cavity), and/or rapid dissolution/degradation in a physiological environment (e.g., intestinal environment) and/or in response to a chemical stimulant (e.
    Type: Grant
    Filed: June 11, 2020
    Date of Patent: February 15, 2022
    Assignees: Massachusetts Institute of Technology, The Brigham and Women's Hospital, Inc.
    Inventors: Andrew Bellinger, Shiyi Zhang, Carlo Giovanni Traverso, Robert S. Langer, Stacy Mo, Tyler Grant, Mousa Jafari, Dean Liang Glettig, Angela DiCiccio, Lowell L. Wood, Jr., Philip A. Eckhoff
  • Patent number: 11246853
    Abstract: Disclosed is a method for evaluating the ability of a chemical substance or a chemical composition to prevent muscle fatigue and damage induced by physical exertion in humans; edible composition including at least one salt of a multivalent metal cation, at least one compound selected between vitamin E or vitamin E acetate, at least one edible polyphenol compound selected from compounds of the flavonol family, compounds of the anthocyanin family, compounds of the phenolic acid family and compounds of the flavonol family and/or the glucosylated derivatives thereof, in which the molar ratio/is of at least 0.50 and not more than 2.00; its use as a food supplement or for preparing a food supplement composition or as a drug for preventing muscle fatigue and/or muscle damage induced by physical exertion, in a method for the treatment of the human body by therapy.
    Type: Grant
    Filed: March 8, 2017
    Date of Patent: February 15, 2022
    Assignee: SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC
    Inventors: Laetitia Cattuzzato, Catherine Kern, Ambre De Pooter
  • Patent number: 11234897
    Abstract: Multi-dose packaged over-the-counter antitussive syrups comprise a bottle containing about 75 ml or less of a liquid formulation of dextromethorphan hydrobromide. The liquid formulation provides at least two doses of dextromethorphan hydrobromide. Multi-dose packaged over-the-counter liquid formulations comprise a bottle having a capacity of about 100 ml or less, at least two doses of the liquid formulation carried within the bottle, a cap, a dosage cup releasably carried on the cap and a shrink wrap substantially enveloping the bottle and the dosage cup. Antitussive syrups comprise water, dextromethorphan hydrobromide in amounts from about 6 to about 25 mg/ml, and sweetener in amounts from about 200 to about 800 mg/ml.
    Type: Grant
    Filed: March 26, 2018
    Date of Patent: February 1, 2022
    Assignee: DXM Pharmaceutical, Inc.
    Inventors: Mark Lawrence Thuesen, Steve Shane Sanders, Steve J. Bannister
  • Patent number: 11234930
    Abstract: Coconut oil, coconut oil blends that are high in MCTs such as LouAna® liquid coconut oil, pure MCT oils, Omega-3 oils, cannabidiol (CBD), hemp extract, tree nut oil, macadamia oil, almond oil, cashew oil, avocado oil, docosahexaenoic acid (DHA), fish oil, and/or conjugated linoleic acid (CLA) may be emulsified to create an emulsified oil or blend that may take the form of a creamy shot or a cream substitute. These oils and/or blends may be emulsified using an emulsifier that may be selected from the following: sunflower lecithin, sodium stearoyl lactylate (SSL), acacia gum, beta-cyclodextrin, and combinations of same. By emulsifying these oils/oil blends, a good tasting creamy shot or a cream substitute can be formed.
    Type: Grant
    Filed: April 13, 2020
    Date of Patent: February 1, 2022
    Inventor: Jesse Windrix
  • Patent number: 11229605
    Abstract: An example device includes at least one three-dimensional (3D) printed tablet and a 3D-printed production support structure. Each 3D-printed tablet includes an excipient material and an active ingredient. The 3D-printed support structure includes a 3D-printed planar structure comprising the excipient material and at least one 3D-printed connecting member comprising the excipient material. The planar structure includes at least one aperture, each aperture corresponding to one of the at least one 3D-printed tablet. The connecting member detachably connects the at least one 3D-printed tablet with the 3D-printed planar structure and positions the at least one 3D-printed tablets within the apertures.
    Type: Grant
    Filed: February 15, 2017
    Date of Patent: January 25, 2022
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Wei Huang, Nathan Moroney, Steven J. Simske, Gary J. Dispoto
  • Patent number: 11229703
    Abstract: A method for inducing abscopal, complete or partial response to radiotherapy comprising administering isoflavone compounds and irradiating with a cytotoxic dose of ionising radiation so that fewer than all of the plurality of tumours are irradiated.
    Type: Grant
    Filed: April 6, 2017
    Date of Patent: January 25, 2022
    Assignee: NOXOPHARM LIMITED
    Inventor: Graham Kelly
  • Patent number: 11216768
    Abstract: A product quality analysis and control system is provided. The product quality analysis and control system includes a processing system that is configured to receive data of objective qualities of a product from multiple data gathering modules. Each of the multiple data gathering modules is respectively positioned at corresponding nodes of a supply chain and is configured to receive from sensors data of objective qualities of a product when the product is at each of the corresponding nodes. The processing system includes a model repository and a data evaluation module. The data evaluation module is configured to select, from the model repository, a model associated with a type of the product and to use the model to analyze the data to identify changes in the objective qualities along the supply chain.
    Type: Grant
    Filed: May 29, 2020
    Date of Patent: January 4, 2022
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Paulo Rodrigo Cavalin, Carmen Nilda Mena Paz, Jaione Tirapu Azpiroz, Ana Paula Appel, Alexandre Alves
  • Patent number: 11197492
    Abstract: An apparatus includes a food product, at least one ingestible device associated with the food product to communicate information and at least one coating material surrounding the at least one ingestible device is disclosed. The ingestible device is associated with an ingestible medication to be ingested in conjunction with the food product. The coating is configured to release the at least one ingestible device upon the occurrence of an event.
    Type: Grant
    Filed: July 17, 2019
    Date of Patent: December 14, 2021
    Assignee: OTSUKA PHARMACEUTICAL CO., LTD.
    Inventors: Lawrence Arne, Mark Zdeblick, Aditya Dua, George Savage, Robert Leichner, Jafar Shenasa, Patricia Johnson, Raymond Schmidt, Zahedeh Hatamkhany, Veeraperumanallu Muralidharan
  • Patent number: 11191750
    Abstract: Disclosed are methods and compositions for the treatment or prevention of intestinal polyps or prevention of cancer in a patient who has been identified as being at risk for developing intestinal polyps or intestinal cancer. The disclosed methods and compositions include rapamycin, a rapamycin analog, or another such inhibitor of the target of rapamycin (TOR).
    Type: Grant
    Filed: June 29, 2020
    Date of Patent: December 7, 2021
    Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Zelton Dave Sharp, Randy Strong, Paul Hasty, Carolina Livi, Arlan Richardson
  • Patent number: 11173167
    Abstract: The present invention provides a composition comprising HMB and Vitamin D. Methods of administering HMB and Vitamin D to an animal are also described. Vitamin D and HMB are administered to increase muscle mass, strength, and functionality. The combination of Vitamin D and HMB together has a synergistic effect, which results in a surprising and unexpected level of improvement in muscle mass, strength and functionality.
    Type: Grant
    Filed: June 17, 2020
    Date of Patent: November 16, 2021
    Assignee: Metabolic Technologies, Inc.
    Inventors: John Rathmacher, John Fuller, Jr., Shawn Baier, Steve Nissen, Naji Abumrad
  • Patent number: 11173170
    Abstract: The present invention relates to a prebiotic composition comprising a galacto oligosaccharide (GOS) produced from Lactobacillus plantarum, wherein the GOS acts as a selective growth medium for a chosen Lactobacillus plantarum probiotic bacterial strain, and wherein the GOS is substantially the same as the form produced by reverse ?-galactosidase reaction in the chosen probiotic bacterial strain. The present invention also relates to methods of producing GOS and related composition incorporating the GOS.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: November 16, 2021
    Assignee: Optibiotix Limited
    Inventors: Stephen Patrick O'Hara, Sofia Kolida
  • Patent number: 11166968
    Abstract: The present invention relates to compositions, particularly compositions useful in maintaining and supporting healthy microflora in the female urogenital tract which could lead to inhibition of vaginal infections, as well as methods of treating and preventing vaginal infections. Compositions useful in supporting healthy microflora, disclosed herein, generally comprise a therapeutic amount of a first saccharide and a therapeutic amount of a second saccharide or an organic acid. The saccharides may be, for example, a pentose, a disaccharide, a cyclodextrin, a pectic substance or a non-digestible polysaccharide. The organic acid may be, for example, malic acid.
    Type: Grant
    Filed: September 29, 2015
    Date of Patent: November 9, 2021
    Assignee: Kimberly-Clark Worldwide, Inc.
    Inventors: Jingru Li, Lindsay Adrienne Peed, Cheryce Francina Joyner, Rebecca Ann Vongsa, David William Koenig, Ryan Daniel Bartell, Paige Nicole Hollmaier