Perthioimidate Esters (i.e., Compounds Having The Perthioimidate Group, Hn=ch-s-s-, Wherein Substitution May Be Made For Hydrogen Only, Bonded Directly To Carbon, Which Carbon May Be Single Bonded To Any Atom But May Be Multiple Bonded Only To Carbon) Patents (Class 560/319)
  • Inhibitors of histone deacetylase
    Patent number: 6541661
    Abstract: The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
    Type: Grant
    Filed: November 22, 2000
    Date of Patent: April 1, 2003
    Assignee: MethylGene, Inc.
    Inventors: Daniel Delorme, Rejean Ruel, Rico Lavoie, Carl Thibault, Elie Abou-Khalil
  • Inhibitors of histone deacetylase
    Patent number: RE39850
    Abstract: The invention relates to the inhibition of histone deactylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
    Type: Grant
    Filed: June 29, 2004
    Date of Patent: September 18, 2007
    Assignee: Methylgene, Inc.
    Inventors: Daniel Delorme, Rico Lavoie, Carl Thibault, Elie Abou-Khalil, Rejean Ruel
  • Inhibitors of histone deacetylase
    Patent number: RE43343
    Abstract: The invention relates to the inhibition of histone deactylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.
    Type: Grant
    Filed: September 10, 2009
    Date of Patent: May 1, 2012
    Assignee: Methylgene Inc.
    Inventors: Daniel Delorme, Rejean Ruel, Rico Lavoie, Carl Thibault, Elie Abou-Khalil