Nitrolic Acids Or Salts Thereof (i.e., Compounds Having The Group -c(=noh)-n(=o) (=o), Wherein The Hydrogen May Be Replaced By A Group Ia Or Iia Light Metal, Or By Substituted Or Unsubstituted Ammonium) Patents (Class 562/620)
Abstract: New types of hydroxamic acid-based bifunctional chelators are provided. These chelators are designed to chelate metal ions that can be detected either by their paramagnetic or radioactive properties. Conjugation with peptides or protein can be achieved by the presence of a linker moiety in the molecular structure of these chelators.
Abstract: Aromatic and heteroaromatic amides of the formula where R1, R2 and R3 can be alkyl, X is alkylene, and R4 is an unsubstituted or substituted aromatic or heteroaromatic group such as naphthyl or fluorenyl, are CNS agents useful for treating pain, depression, anxiety, seizures, and schizophrenia.
May 10, 2000
Date of Patent:
January 25, 2005
Warner Lambert Company
Justin Stephen Bryans, John Colm O'Toole, David Christopher Horwell