Glucose Measurement Patents (Class 600/365)
  • Patent number: 11923880
    Abstract: An electromagnetic (EM)-based diagnostics and monitoring system and method for the non-Invasive diagnosis and monitoring of in-vivo and ex-vivo Skin Anomalies Using Lesion-Optimized Sensor System Design and Topology is disclosed herein.
    Type: Grant
    Filed: May 25, 2022
    Date of Patent: March 5, 2024
    Assignee: American University of Beirut
    Inventors: Nader Shafi, Joseph Costantine, Rouwaida Kanj, Youssef Tawk, Assaad Eid, Mazen Kurban, Jihane Abou Rahal, Ali H. Ramadan
  • Patent number: 11899552
    Abstract: An estimating device includes processing circuitry configured to estimate a median of intervals between adjacent data pieces in input time-series data as a uniform interval for the time-series data, and extract data pieces at the estimated uniform intervals from the input time-series data.
    Type: Grant
    Filed: May 9, 2019
    Date of Patent: February 13, 2024
    Assignee: NIPPON TELEGRAPH AND TELEPHONE CORPORATION
    Inventors: Tetsuya Shioda, Miki Sakai, Kazuki Oikawa, Masakuni Ishii
  • Patent number: 11887715
    Abstract: Adaptive on board estimation of exogenous pharmacon responsive to transient (i.e., impermanent) physiological effects is provided. Dynamically estimating an equivalent amount of an exogenous pharmacon on board (XOB), such as insulin and/or carbohydrates, left in the subject, is based on predictions of glucose time-series data. These estimated values, such as insulin on board (IOB), are useful for diabetes management software, including decision support and/or artificial pancreas (AP) algorithms, for example.
    Type: Grant
    Filed: June 19, 2020
    Date of Patent: January 30, 2024
    Assignee: DEXCOM, INC.
    Inventors: Stephen D. Patek, Enrique Campos-Náñez
  • Patent number: 11877847
    Abstract: A biosensor apparatus comprises a biosensor device and a cover that is configured to attach to the biosensor device. The biosensor device includes a surface section that is disposed above the user's skin and an implantable section that is injected into the user's skin. The implantable section includes a bending detector and sensing circuitry. The sensing circuitry includes one or multiples of a biomarker sensor array, a control biomarker sensor array, a temperature sensor, and/or a biofouling detector.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: January 23, 2024
    Assignee: TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD.
    Inventors: Yu-Jie Huang, Jui-Cheng Huang, Allen Timothy Chang
  • Patent number: 11874267
    Abstract: A system for testing properties of a sample, the system including a test cell. The test cell includes a cell casing having a first end piece, a second end piece, and at least one wall extending between the first end piece and the second end piece. The cell casing defines a pressure boundary enclosing an interior region of the cell. The test cell further includes a sample chamber, a first reservoir, and a second reservoir disposed within the pressure boundary. The sample chamber defines an interior region. The first reservoir fluidly connects to the interior region of the sample chamber. The second reservoir fluidly connects to the interior region of the sample chamber. The test cell also has a piston assembly having a piston fluid chamber and a piston with a stem extending into the piston fluid chamber. The piston partially defines the sample chamber.
    Type: Grant
    Filed: December 6, 2021
    Date of Patent: January 16, 2024
    Assignee: Saudi Arabian Oil Company
    Inventor: Mustafa Hakimuddin
  • Patent number: 11864887
    Abstract: In diabetes management applications, recent glucose measurement values may be clinically useful for acute diagnosis and for the calculation of a corrective therapy. However, the physiological significance of these measurements can lessen with time, which can lead to their becoming less relevant for calculating an effective therapy. A technique is presented for emphasizing analyte values in a diabetes management application during a therapeutic window. In this way, a user is notified that the glucose measurement value is the most current measurement and remains usable for therapy applications, such as an insulin bolus calculation.
    Type: Grant
    Filed: October 20, 2017
    Date of Patent: January 9, 2024
    Assignee: Roche Diabetes Care, Inc.
    Inventors: Eric S. Carlsgaard, Nils Babion
  • Patent number: 11864889
    Abstract: A system, apparatus, and device estimate the state of the glucose metabolism of the subject based on a correlation between a blood glucose level of the subject acquired in advance and an index which is based on the pulse wave of the subject associated with the blood glucose level.
    Type: Grant
    Filed: October 27, 2020
    Date of Patent: January 9, 2024
    Assignee: KYOCERA Corporation
    Inventor: Hiromi Ajima
  • Patent number: 11857262
    Abstract: An intraocular pressure (IOP) sensing system may comprise an intraocular pressure sensing implant to be implanted into the eye of a patient for capturing absolute intraocular pressure measurements and an external device for capturing atmospheric pressure measurements. The intraocular pressure sensing implant may be configured to capture an absolute intraocular pressure measurement at an appointed time, and the external device may be configured to capture a plurality of atmospheric pressure measurements around the appointed time.
    Type: Grant
    Filed: September 28, 2018
    Date of Patent: January 2, 2024
    Assignee: GLAUKOS CORPORATION
    Inventors: Nicholas Gunn, Cesario Pereira Dos Santos, David S. Haffner
  • Patent number: 11854681
    Abstract: A data management unit for supporting health control, the unit including: a processor, a data input adapted to input data and/or requests and connected to the processor, a data storage connected to the processor, wherein the processor is adapted to assign a tag referring to an event chosen from a group of tags comprising the fasting tag and at least one other event tag to a new data received from the data input or a measurement unit, wherein the tag is assigned either automatically by the processor and/or via the data input, wherein the fasting tag can only be assigned to the new data if a time stamp of the new data is within a predefined fasting window, wherein the predefined fasting window is stored in the data storage.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: December 26, 2023
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Axel Teucher, Florian Schauderna, Jochen Sieber, Alexandra Beer, Frank Roethke, Frank Flacke, Andrew Tubb, Ashley Engelhardt, Joseph Pomata, Margaret Wiley, Thora Thorgilsdottir, Alyssa Rosenzweig
  • Patent number: 11846600
    Abstract: Circuitry for measuring a characteristic of an electrochemical cell, the circuitry comprising: a comparator having a first comparator input, a second comparator input and a comparator output; a feedback path between the comparator output and the second comparator input configured to provide a feedback signal to the second comparator input; and a loop filter configured to apply filtering to the feedback path to generate the feedback signal, wherein the loop filter comprises the electrochemical cell.
    Type: Grant
    Filed: September 1, 2021
    Date of Patent: December 19, 2023
    Assignee: Cirrus Logic Inc.
    Inventors: John P. Lesso, Toru Ido
  • Patent number: 11833327
    Abstract: A method of automatically initializing an analyte sensor for a user is disclosed here. A first analyte sensor is operated in a first measurement mode to generate first sensor signals indicative of an analyte level of the user. A second analyte sensor is deployed to measure the analyte level of the user, and is operated in an initialization mode, concurrently with operation of the first analyte sensor in the first measurement mode, to receive sensor configuration data generated by the first analyte sensor. During operation of the second analyte sensor in the initialization mode, the second analyte sensor is calibrated with at least some of the received sensor configuration data. After the calibrating, operation of the second analyte sensor is transitioned from the initialization mode to a second measurement mode during which the second analyte sensor generates second sensor signals indicative of the analyte level of the user.
    Type: Grant
    Filed: March 6, 2020
    Date of Patent: December 5, 2023
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Erik Montero, David C. Antonio, Eric Allan Larson, Meng Dai Yu, Samuel Finney, Hans K. Wenstad, David M. Aguirre, Andrew P. Lynch, Andrea Varsavsky, Ali Dianaty
  • Patent number: 11835717
    Abstract: Disclosed herein are systems and methods for device authentication or pairing. In an aspect, a wearable display system comprises a display, an image capture device configured to capture images of a companion device, a computer-readable storage medium configured to store the images of the companion device, and a processor in communication with the image capture device and the storage medium. The processor can be programmed with executable instructions to receive a first image of a first optical pattern displayed by the companion device captured by the image capture device, wherein the first optical pattern is generated by the companion device based on first shared data, extract first data from the first optical pattern in the received first image, authenticate the companion device based on the first data extracted from the first optical pattern, and notify a user of the wearable display system that the companion device is authenticated.
    Type: Grant
    Filed: February 18, 2021
    Date of Patent: December 5, 2023
    Assignee: Magic Leap, Inc.
    Inventors: Nitin Singh, Adrian Kaehler
  • Patent number: 11823783
    Abstract: Adaptive on board estimation of exogenous pharmacon responsive to transient (i.e., impermanent) physiological effects is provided. Dynamically estimating an equivalent amount of an exogenous pharmacon on board (XOB), such as insulin and/or carbohydrates, left in the subject, is based on predictions of glucose time-series data. These estimated values, such as insulin on board (IOB), are useful for diabetes management software, including decision support and/or artificial pancreas (AP) algorithms, for example.
    Type: Grant
    Filed: June 19, 2020
    Date of Patent: November 21, 2023
    Assignee: Dexcom, Inc.
    Inventors: Stephen D. Patek, Enrique Campos-Náñez
  • Patent number: 11823784
    Abstract: A portable therapeutic platform for use in a therapeutic procedure including: (a) at least one compartment for holding at least one therapeutically effective item required to conduct the therapeutic procedure; and (b) at least one electronic communications device for receiving and transmitting information about an environment surrounding and including the platform. The use of the platform is conveniently managed by a system which transfers information about the environment surrounding and including the platform between the electronic communications device and a computer system including a processor which processes the information; and initiates a control response to the processed information. The platform and system are suitable for use to address a range of public health issues and as a countermeasure to biosecurity threats.
    Type: Grant
    Filed: January 30, 2019
    Date of Patent: November 21, 2023
    Inventor: David Wearne
  • Patent number: 11810652
    Abstract: Systems, methods and computer-readable media are provided for predicting candidacy for Kidney Surgery and related computer-performed decision support. In particular, embodiments of the disclosure are directed to identifying populations of patients who are candidates for vascular access placement in Chronic Kidney Disease (CKD). Some embodiments of the present disclosure provide a system and method for continually tracking the clinical and physiologic status of a patient in a hospital. At least some of the embodiments assist nephrologists in preventing and reducing the frequency of crises in urgent/emergent presentation with requirement for dialysis (“crashing onto dialysis”) by using the systems' capability to recognize patterns in a patient's eGFR and serum uric acid values before the patient deteriorates or reaches a crisis.
    Type: Grant
    Filed: September 1, 2020
    Date of Patent: November 7, 2023
    Assignee: Cerner Innovation, Inc.
    Inventor: Douglas S. McNair
  • Patent number: 11806514
    Abstract: One or more embodiments of the present disclosure may include an insulin delivery system that includes an insulin delivery device, a user interface that includes multiple user-selectable icons or buttons each representing different meal characteristics, memory to store one or more user-specific dosage parameter, and a processor in communication with the memory and adapted to receive blood glucose data. The processor may also be adapted to determine initial meal characteristics associated with each of the user-selectable icons or buttons based on at least one of the user-specific dosage parameters. The processor may also be adapted to update the meal characteristics associated with each of the user-selectable icons or buttons based upon the blood glucose data.
    Type: Grant
    Filed: September 10, 2019
    Date of Patent: November 7, 2023
    Assignee: Bigfoot Biomedical, Inc.
    Inventors: Per John Sjolund, Lane Desborough, Bryan Mazlish, Andrew Bochenko, Ross Naylor
  • Patent number: 11804289
    Abstract: Systems and methods are provided for identifying therapeutic zones where there is glycemic dysfunction of a specific type that can be addressed by making strategic changes to behavior and/or therapy parameters. Systems and methods described herein evaluate large historical data sets to: identify a therapeutic zone or zones with glycemic dysfunction that are most readily addressable; quantify the glycemic impact of a plurality of different therapeutic adjustments in terms of either adjustments to historical doses or the parameters of a prospective dosing strategy to determine the highest possible improvement; and/or identify patient dosing strategies to provide therapy recommendations adapted for the patient's preferred behavioral dosing strategy.
    Type: Grant
    Filed: December 16, 2020
    Date of Patent: October 31, 2023
    Assignee: DEXCOM, INC.
    Inventor: Stephen D. Patek
  • Patent number: 11783946
    Abstract: A method of administering insulin includes receiving blood glucose measurements of a patient at a data processing device from a glucometer. Each blood glucose measurement is separated by a time interval and includes a blood glucose time associated with a time of measuring the blood glucose measurement. The method also includes receiving patient information at the data processing device and selecting a subcutaneous insulin treatment for tube-fed patients from a collection of subcutaneous insulin treatments. The selection is based on the blood glucose measurements and the patient information. The subcutaneous insulin treatment program for tube-fed patients determines recommended insulin doses based on the blood glucose times. The method also includes executing, using the data processing device, the selected subcutaneous insulin treatment.
    Type: Grant
    Filed: July 19, 2022
    Date of Patent: October 10, 2023
    Assignee: Aseko, Inc.
    Inventors: Robert C. Booth, Harry Hebblewhite
  • Patent number: 11727547
    Abstract: Systems and methods for testing visible chemical reactions of a reagent are provided. In one implementation, the method may include receiving from an image sensor associated with a mobile communications device an image of a reagent with a plurality of colored test reagent pads in proximity to a colorized surface having a plurality of colored reference elements of differing shades. The method further includes using the differing shades of the plurality of colored reference elements to determine local illumination conditions. Thereafter, the method includes using the determined local illumination conditions and an analysis of a depiction of the plurality of colored test reagent pads in the image to determine an extent of a chemical reaction on the reagent. Then the method includes causing the mobile communications device to provide to the user an indication that the testing of the reagent is complete.
    Type: Grant
    Filed: July 7, 2021
    Date of Patent: August 15, 2023
    Assignee: HEALTHY.IO LTD.
    Inventors: Yonatan Adiri, Ido Omer, Ron Zohar
  • Patent number: 11701023
    Abstract: A method, system, apparatus, and/or device for measuring a physiological condition of a user. The method, system, apparatus, and/or device may include: a band configured to attach to a body part of a user; a housing coupled to the band; a processing device integrated into the band or disposed within the housing; an interface integrated into the band or disposed within the housing; and a miniaturized impedance sensor.
    Type: Grant
    Filed: October 30, 2019
    Date of Patent: July 18, 2023
    Assignee: Brigham Young University
    Inventors: Robert Davis, Nick Morrill, David Miller
  • Patent number: 11703494
    Abstract: A measuring apparatus for determining at least one measurand of a measuring medium includes a first measuring device including a first measuring sensor structured to contact the measuring medium and configured to detect measured values of the at least one measurand, the first measuring device embodied to determine a first measured value that is dependent on the at least one measurand of the measuring medium, a sampling device structured to remove a sample from the measuring medium, a second measuring device including a second measuring sensor and embodied to determine a second measured value that is dependent on the least one measurand of the sample, and an electronic control apparatus configured to receive and process the first and second measured value and to perform a verification, calibration and/or adjustment of the first measuring device using the second measured value.
    Type: Grant
    Filed: February 12, 2020
    Date of Patent: July 18, 2023
    Assignee: Endress+Hauser Conducta GmbH+Co. KG
    Inventors: Thomas Alber, Joachim Albert, Ralf Steuerwald, Michael Hanko, Angela Eubisch
  • Patent number: 11696728
    Abstract: An amount of glycemic dysfunction associated with mis-timing (e.g., delay) of meal boluses based on replay analysis is determined. The amount of dysfunction of historical or estimated bolusing as compared to an optimally timed bolus based on the replay analysis is quantified and visualized. Inferences may be made about diabetes meal management regarding inputs from a patient.
    Type: Grant
    Filed: December 19, 2019
    Date of Patent: July 11, 2023
    Assignee: Dexcom, Inc.
    Inventors: Stephen D. Patek, Stephen J. Vanslyke
  • Patent number: 11694785
    Abstract: A method of administering insulin includes receiving scheduled glucose time intervals and obtaining glucose data of a patient that includes glucose measurements, glucose times, and insulin dosages previously administered by the patient. The method also includes applying a set of filters to identify which of the glucose measurements associated with at least one of the scheduled time intervals are usable and which of the glucose measurements associated with the at least one scheduled time interval are unusable. The method also includes aggregating the glucose measurements associated with the at least one scheduled time interval identified as usable to determine a representative aggregate glucose measurement and determining a next recommended insulin dosage for the patient based on the representative aggregate glucose measurement and the insulin dosages previously administered by the patient.
    Type: Grant
    Filed: July 12, 2021
    Date of Patent: July 4, 2023
    Assignee: Aseko, Inc.
    Inventors: Robert C. Booth, Harry Hebblewhite
  • Patent number: 11672446
    Abstract: Disclosed herein are techniques related to insulin delivery recommendations based on nutritional information. In some embodiments, the techniques may involve obtaining user input indicative of quantitative information for a food item. The techniques may further involve determining, based on the user input, nutritional information for the food item. Additionally, the techniques may involve generating, based on the nutritional information, an insulin delivery recommendation.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: June 13, 2023
    Assignee: MEDTRONIC MINIMED, INC.
    Inventors: Yaron Hadad, Jonathan Lipnik
  • Patent number: 11663315
    Abstract: A computer system for just-in-time authentication displays a user interface comprising a first portion and a second portion. The first portion of the user interface is associated with a first permission attribute, and the second portion of the user interface is associated with a second permission attribute. The first permission attribute is associated with a first user and the second permission attribute is associated with a second user. The computer system receives, from one or more proximity sensors, a proximity of the second user relative to the user interface. The computer system also receives, from an identity-verification sensor, a verification of an identification of the second user. Further, the computer system activates the second portion of the user interface for interaction from the second user.
    Type: Grant
    Filed: January 29, 2021
    Date of Patent: May 30, 2023
    Assignee: MasterControl Solutions, Inc.
    Inventors: Chad Milito, Terrance Lanham Holbrook, Brian Curran, Alan Rencher
  • Patent number: 11642054
    Abstract: In some aspects, an apparatus for a biosensor includes a sensor wire and a rigid member. The rigid member may be coupled to the sensor wire and include a contact surface. The contact surface may be sized to enable a suction head of a robotic placement device to create a vacuum seal on the contact surface for lifting the sensor wire and rigid member.
    Type: Grant
    Filed: June 2, 2020
    Date of Patent: May 9, 2023
    Assignee: DexCom, Inc.
    Inventors: Ohseung Kwon, Xianyan Wang, Timothy Stowe
  • Patent number: 11627897
    Abstract: This disclosure concerns a medical device and a method for its production, wherein the device comprises a cannula having an elongated hollow shaft and a sharp tip provided at a distal end of the shaft, wherein the shaft is formed as a bent part from a sheet material and confines an interior passage which has a lateral slit opening, and wherein the shaft has at least one longitudinal pre-bending channel provided in the sheet material, wherein the thickness of the sheet material is reduced along the pre-bending channel and a sidewall of the shaft is folded over the pre-bending channel.
    Type: Grant
    Filed: July 20, 2018
    Date of Patent: April 18, 2023
    Assignee: Roche Diabetes Care, Inc.
    Inventor: Herbert Harttig
  • Patent number: 11619624
    Abstract: The health support system according to a preferred embodiment includes a sensor that outputs an output signal corresponding to a specific component in urine, a transmitter connected to the sensor, and a user terminal carried by the user. The user terminal includes a storage unit that stores an identifier corresponding to the user, a wireless receiving unit that receives a wireless signal from the transmitter, an output unit that outputs the data to an analysis system that analyzes the health state of the user based on a specific component indicated by the data when the identifier indicated by the wireless signal matches the identifier stored in the storage unit, and an acquisition unit that acquires information corresponding to the results of the analysis of the analysis system.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: April 4, 2023
    Inventors: Yohei Kanazawa, Yoshito Tsunoda
  • Patent number: 11593204
    Abstract: An approach to identifying a corrective action for a data storage device (DSD), such as one implemented in a fleet of DSDs in a data center, involves receiving error data about excursions from normal operational behavior of the DSD, inputting data representing a particular excursion into a probabilistic decision network which characterizes a set of DSD operational metrics and certain DSD controller rules that represent internal controls of the DSD and corresponding conditional relationships among the operational metrics, determining from the decision network the likelihood that one or more possible causes was a contributing factor to the particular excursion, and determining a corrective action for the particular excursion based on the determined likelihood of a particular cause of the one or more possible causes. The corrective action may then be shared with the DSD for in-situ execution of corresponding self-repair operations.
    Type: Grant
    Filed: May 27, 2021
    Date of Patent: February 28, 2023
    Assignee: Western Digital Technologies, Inc.
    Inventors: Bernd Lamberts, Jeffrey Hobbet, Maulik Thaker, Evan Richardson, Remmelt Pit
  • Patent number: 11587672
    Abstract: Introduced here are diabetes management platforms able to guide people with diabetes toward a glycemic target. Rather than state the absolute amount of glucose within the blood, the diabetes management platform can instead produce personalized glycemic goals based on the physiological data associated with an individual. For example, if the diabetes management platform determines that the time spent within a first glycemic range exceeds a specified threshold, then the diabetes management platform may recommend that the individual attempt to keep their blood glucose level within a second glycemic range. Generally, the second glycemic range is closer than the first glycemic range to a target glycemic range corresponding to a healthy glycemic state.
    Type: Grant
    Filed: August 9, 2019
    Date of Patent: February 21, 2023
    Assignee: Verily Life Sciences LLC
    Inventors: Nikhil Roy, Howard Zisser
  • Patent number: 11579157
    Abstract: A dashboard interface may be displayed on a lab instrument to provide aggregate status information from a plurality of other interfaces organized into a single interface. The aggregate status information may be viewed by a nearby user of the lab instrument, and selecting portions of the information via a touchscreen display will navigate directly to a subsequent interface that may be used to view additional information or make configuration changes relating to the selected information. The dashboard may be used as a screensaver on a lab instrument when the instrument is not in use, or may be navigated to by an active user of a lab instrument, or both.
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: February 14, 2023
    Assignee: Beckman Coulter, Inc.
    Inventors: Adam Matthew Torres, Hernando Salas
  • Patent number: 11576592
    Abstract: A method of characterising tremor stability in a subject is described for a subject having an involuntary tremor symptomatic of a neurological disorder. The method comprising: identifying a series of tremor cycles from measured tremor data of the subject, said tremor cycles measuring periodic variation in movement of the subject due to the tremor; determining an instantaneous frequency for each tremor cycle and collating the instantaneous frequencies; determining an instantaneous variation between the instantaneous frequencies of each pair of adjacent tremor cycles within the series; comparing the instantaneous variation to the collation of determined instantaneous frequencies to determine a distribution of instantaneous variations; and determining an index value of the distribution of the instantaneous variations, said index value defining the stability of the tremor.
    Type: Grant
    Filed: January 17, 2018
    Date of Patent: February 14, 2023
    Assignee: OXFORD UNIVERSITY INNOVATION LIMITED
    Inventors: Lazzaro Di Biase, John-Stuart Brittain, Brown Peter, Vincenzo Di Lazzaro, Syed Ahmar Shah
  • Patent number: 11564636
    Abstract: Systems and methods for health and body simulations in order to predict numerous physiological parameters in a subject or a population of subjects based on the input of limited physiological data.
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: January 31, 2023
    Assignee: PricewaterhouseCoopers LLP
    Inventors: Paul M. D'Alessandro, Mark Paich, Samuel Pierce Burns, Joydeep Sarkar, Gaurav Dwivedi, Colleen Chelini
  • Patent number: 11564637
    Abstract: Systems and methods for health and body simulations in order to predict numerous physiological parameters in a subject or a population of subjects based on the input of limited physiological data.
    Type: Grant
    Filed: August 1, 2019
    Date of Patent: January 31, 2023
    Assignee: PricewaterhouseCoopers LLP
    Inventors: Paul M. D'Alessandro, Mark Paich, Samuel Pierce Burns, Joydeep Sarkar, Gaurav Dwivedi, Colleen Chelini
  • Patent number: 11559229
    Abstract: Devices and methods are provided for continuous measurement of an analyte concentration. The device can include a sensor having a plurality of sensor elements, each having at least one characteristic that is different from other sensor(s) of the device. In some embodiments, the plurality of sensor elements are each tuned to measure a different range of analyte concentration, thereby providing the device with the capability of achieving a substantially consistent level of measurement accuracy across a physiologically relevant range. In other embodiments, the device includes a plurality of sensor elements each tuned to measure during different time periods after insertion or implantation, thereby providing the sensor with the capability to continuously and accurately measure analyte concentrations across a wide range of time periods.
    Type: Grant
    Filed: August 9, 2019
    Date of Patent: January 24, 2023
    Assignee: Dexcom, Inc.
    Inventors: Peter C. Simpson, Robert J. Boock, Apurv Ullas Kamath, Matthew D. Wightlin, Michael J. Estes
  • Patent number: 11561541
    Abstract: An infrastructure is provided for improving the safety of autonomous systems. An autonomous vehicle management system (AVMS) controls one or more autonomous functions or operations performed by a vehicle or machine such that the autonomous operations are performed in a safe manner. The AVMS is capable of dynamically controlling the behavior of sensors associated with a vehicle. For example, for a sensor, the AVMS can dynamically change and control what sensor data is captured by the sensor and/or communicated from the sensor to the AVMS (e.g., granularity/resolution, field of view, control zoom), when the data is captured by the sensor and/or communicated by the sensor to the AVMS (e.g., on-demand, according to a schedule), and how the data is captured by the sensor and/or communicated from the sensor to the AVMS (e.g., communication format, communication protocol, rate of data communication).
    Type: Grant
    Filed: April 8, 2019
    Date of Patent: January 24, 2023
    Assignee: SafeAI, Inc.
    Inventor: Bibhrajit Halder
  • Patent number: 11562824
    Abstract: Disclosed is a portable device for collecting and processing continuous monitoring data. The device has a data interface configured to receive a stream of continuous monitoring data from a body-worn sensor, the continuous monitoring data being indicative of an analyte in a bodily fluid. A control is connectable to the data interface. The control controls a first mode of operation during which configuration parameters are established in response to receiving a start signal indicating a sensor session start of the body-worn sensor. The control also controls a second mode of operation during which the continuous monitoring data is collected and processed and also controls the switching from the first mode to the second mode. The control blocks further starting of the first mode for a remaining sensor session time after the switching to the second mode of operation. Also disclosed are a related medical system, method and computer program product.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: January 24, 2023
    Assignee: Roche Diabetes Care, Inc.
    Inventor: Bernd Steiger
  • Patent number: 11540752
    Abstract: Systems, methods, and devices of a health device network may include: a non-invasive glucometer that non-invasively measures analyte levels; an invasive glucometer communicatively coupled directly to the non-invasive glucometer; a cloud-based server communicatively coupled to the non-invasive glucometer or the invasive glucometer; a user device communicatively coupled to the cloud-based server; and/or a user interface that displays the invasive glucose measurement, the non-invasive glucose measurement, a data batch, and/or processed data to the user. The non-invasive glucometer and/or the invasive glucometer may aggregate an invasive glucose measurement and a non-invasive glucose measurement into the data batch.
    Type: Grant
    Filed: March 25, 2020
    Date of Patent: January 3, 2023
    Assignee: Tula Health, Inc.
    Inventors: David Miller, Devin Miller, Michael Jones, David Derrick
  • Patent number: 11540750
    Abstract: A physiological characteristic monitoring system includes a physiological characteristic sensor that observes a physiological characteristic and generates sensor signals based on the observation. The physiological characteristic sensor includes a sensor connector. The physiological characteristic monitoring system includes a wearable device to be worn by a user in a first configuration and having a connector to couple to the sensor connector in a second configuration. The wearable device includes a controller that receives the sensor signals from the physiological characteristic sensor in the second configuration and determines a current value of the physiological characteristic based on the sensor signals.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: January 3, 2023
    Assignee: MEDTRONIC MINIMED, INC
    Inventors: Santhisagar Vaddiraju, Bejan M. Darbandi, Nicholas S. Mairs, Brian Ross
  • Patent number: 11545015
    Abstract: A method, system, apparatus, and/or device that may include: determining, by a processor, that an alert event has occurred; determining, by the processor, a level of the alert event, wherein the level of the alert event is a caution alert level, an urgent alert level, or a critical alert level; determining, by the processor, an initial alert activity associated with the caution alert level, the urgent alert level, or the critical alert level; performing, by the processor, the initial alert activity receiving, from an input device, an updated alert activity associated with the caution alert level, the urgent alert level, or the critical alert level; and in response to that the initial alert activity conflicting with the updated alert activity, maintaining, by the processor, using the initial alert activity associated with the caution alert level, the urgent alert level, or the critical alert level.
    Type: Grant
    Filed: December 7, 2020
    Date of Patent: January 3, 2023
    Assignee: Tula Health, Inc.
    Inventors: Jeffrey Lee, Michael Jones, Federico Calero, Trevor Calero, Devin Miller, David Miller
  • Patent number: 11510570
    Abstract: A system is provided for monitoring analyte in a host, including a continuous analyte sensor that produces a data stream indicative of a host's analyte concentration and a device that receives and records data from the data stream from the continuous analyte sensor. In one embodiment, the device includes a single point analyte monitor, from which it obtains an analyte value, and is configured to display only single point analyte measurement values, and not any analyte measurement values associated with data received from the continuous analyte sensor. Instead, data received from the continuous analyte sensor is used to provide alarms to the user when the analyte concentration and/or the rate of change of analyte concentration, as measured by the continuous analyte sensor, is above or below a predetermined range. Data received from the continuous analyte sensor may also be used to prompt the diabetic or caregiver to take certain actions, such as to perform another single point blood glucose measurement.
    Type: Grant
    Filed: July 7, 2020
    Date of Patent: November 29, 2022
    Assignee: Dexcom, Inc.
    Inventors: Jorge Valdes, David Price, Leif N. Bowman, Kristin Koenekamp Cote
  • Patent number: 11514609
    Abstract: A detection system method of color balancing an image includes receiving an image of a test area of a pad which includes a color of a reaction between a test substance and at least one reagent on the test area of the pad, an alignment code having detection system identification information, at least one color calibration block indicia for aligning with a camera as the image is being captured, and test identification information for analyzing the test substance during a colorimetric analysis. The method further includes collecting an array of pixels of RGB values for each pixel in the image, evaluating a captured color of the at least one color calibration block in the image, and performing the colorimetric analysis on the reaction between the test substance and the at least one reagent.
    Type: Grant
    Filed: May 30, 2019
    Date of Patent: November 29, 2022
    Assignee: DETECTACHEM, INC.
    Inventors: Travis Kisner, Aaron Sanders
  • Patent number: 11497855
    Abstract: A smart drug injection device is disclosed, comprising a main body, a circuit board, a display, a syringe and a transmission mechanism; the main body comprises an accommodating space and a power button; the circuit board comprises a control unit and a storage unit; the transmission mechanism comprises a motor, a screw rod, a propelling block and a movable clamp, with the control unit electrically connected to the storage unit, the power button, the motor and the display, the motor connected to the screw rod, the propelling block movably arranged on the screw rod, the movable clamp disposed at one end of the propelling block and movable between two positions; the syringe is on one side of the main body and comprises a cylinder and a needle holder, one end of the cylinder has a needle and the other end is assembled with the needle holder.
    Type: Grant
    Filed: October 13, 2020
    Date of Patent: November 15, 2022
    Assignee: AINOS, INC.
    Inventors: Stephen T. Chen, Hsien-Yao Chiu
  • Patent number: 11484232
    Abstract: This document discusses, among other things, systems and methods to compensate for the effects of temperature on sensors, such as analyte sensor. An example method may include determining a temperature-compensated glucose concentration level by receiving a temperature signal indicative of a temperature parameter of an external component, receiving a glucose signal indicative of an in vivo glucose concentration level, and determining a compensated glucose concentration level based on the glucose signal, the temperature signal, and a delay parameter.
    Type: Grant
    Filed: January 22, 2019
    Date of Patent: November 1, 2022
    Assignee: Dexcom, Inc.
    Inventors: Anna Claire Harley-Trochimczyk, Sebastian Böhm, Rui Ma, Disha B. Sheth, Minglian Shi, Kamuran Turksoy
  • Patent number: 11475988
    Abstract: Introduced here are diabetes management platforms able to impute blood glucose level values for a subject whose glycemic health state is being monitored. These imputed values can be used to estimate the glycemic health state of the subject at a given point in time, identify appropriate recommendations for improving the glycemic health state, etc. More specifically, a diabetes management platform can initially acquire one or more explicit data values generated by a glucose monitoring device. The diabetes management platform can then design a statistical model for imputing data values based on the one or more explicit data values. The diabetes management platform may employ several different computational techniques for performing imputation.
    Type: Grant
    Filed: January 16, 2019
    Date of Patent: October 18, 2022
    Assignee: Verily Ufe Sciences LLC
    Inventors: Joshua Burkart, Nathan Dickerson Beach
  • Patent number: 11464461
    Abstract: Introduced here are diabetes management platforms able to make annotations to physiological data of a subject whose glycemic health state is being monitored. These annotations can be used to classify excursions detected in the physiological data to facilitate the identification of a therapeutic behavior change intended to improve the glycemic health state of the subject. For example, a health coach may review the annotation(s) associated with the subject before generating a recommendation for improving the glycemic health state. As another example, the diabetes management platform can automatically identify an appropriate recommendation based on the annotation(s).
    Type: Grant
    Filed: March 11, 2020
    Date of Patent: October 11, 2022
    Assignee: Verily Life Sciences LLC
    Inventors: William Jacob Benhardt Biesinger, Joshua Burkart
  • Patent number: 11452474
    Abstract: A system includes an applicator and a dermal patch coupled to the applicator. The applicator includes a needle configured to puncture a subject's skin to draw a physiological sample, a first actuating lever configured to move form an undeployed position to a deployed position, and a second actuating lever configured to move form an undeployed position to a deployed position. The dermal patch includes a fluid reservoir configured to store a processing fluid, a sample collection chamber configured to receive the processing fluid and the physiological sample, wherein the applicator is configured to cause the needle to puncture the subject's skin to draw the physiological sample when the first actuating lever is moved from the undeployed lever position to the deployed lever position and cause the processing fluid to release from the fluid reservoir when the second actuating lever is moved from the undeployed position to the deployed position.
    Type: Grant
    Filed: August 25, 2021
    Date of Patent: September 27, 2022
    Assignee: Satio, Inc.
    Inventors: Namai Nawana, Ziad Tarik Al-Shamsie
  • Patent number: 11443649
    Abstract: A training simulator for intraoperative neuromonitoring (IONM) systems includes channels where at least one of the channels is identified as an active stimulation channel and a subset of the rest of the channels is identified as reference or pick up sites. Channels of the subset having signal data that exceed a predefined threshold are retained for further processing, while channels with signal data that do not exceed the threshold are eliminated from further reporting. Response data for the remaining channels are generated in advance of a future time when the response would occur. The generated data is time stamped and stored for display at a time window when requested by the system.
    Type: Grant
    Filed: June 28, 2019
    Date of Patent: September 13, 2022
    Inventors: John A. Cadwell, Melissa Miles, Mark Romero
  • Patent number: 11439750
    Abstract: A medication delivery patch that is applied to the skin and activated to deliver a medication or other fluid into or through the skin. The patch may be completely mechanically driven, with no electronic components, for low cost, safety, and reliability. Pressing an activation button may set in motion a sequence of mechanical events that result in a needle exiting the patch into the skin of the user, and flow of fluid from an internal pouch in the patch into the user. When delivery is complete, another sequence of mechanical events may occur to retract the needle from the skin and stop the flow of fluid, and to show a visible indicator that delivery is complete. The patch may contain a fluid channel, such as a microfluidic channel, that controls the rate and time of delivery; this channel can be configured or selected for different medications or use cases.
    Type: Grant
    Filed: December 8, 2021
    Date of Patent: September 13, 2022
    Inventor: Gina G. Stetsko
  • Patent number: 11416064
    Abstract: Disclosed herein is a method of enabling supervision of a laboratory environment utilizing diagnostic equipment. The method includes utilization of a device for capturing an optical image of at least a portion of the laboratory environment. The method further requires selectively capturing the optical image using the image capture device and selectively transmitting the captured image over a communications medium. The method further requires receiving the transmitted optical image by an image receiver in communication with the image transmission device via the communications medium. The method then requires selectively generating, by an image processor in communication with the image receiver, a display of at least a portion of the captured optical image on an image display device and receiving status information from the diagnostic equipment at a laboratory manager that is in communication with multitude of diagnostic equipment.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: August 16, 2022
    Assignee: Siemens Healthcare Diagnostics Inc.
    Inventor: Sandeep M. Naik