Abstract: A method for delivering ultrasound therapy using open-loop controls comprises inserting a distal tip of a therapeutic ultrasound applicator into a patient's urethra, the distal tip including an ultrasound transducer; acquiring ultrasound images of the patient's urethra and prostate with an ultrasound imaging probe; aligning the distal tip of the therapeutic ultrasound applicator with the patient's prostate using the ultrasound images; delivering therapeutic ultrasound energy to the patient's prostate, with the ultrasound transducer, according to a treatment plan, the treatment plan including a predetermined limited angular range for the therapeutic ultrasound energy that avoids the patient's rectum and neurovascular bundles, wherein the therapeutic ultrasound is delivered without temperature feedback data.

Abstract: According to the present invention, a transducer part is mechanically scanned in a chamber for a medium. A pair of diaphragms are provided to the two sides of the transducer part (one side and the other side in the mechanical scanning direction). Each of the diaphragms has a hollow membrane and a base. The hollow membrane has a pair of longitudinal lateral surfaces extending in a longitudinal direction parallel to the center axis of rotation. An attachment hole is formed in a partition wall, and a projecting part provided on the base is inserted into the attachment hole.

Abstract: A catheterization system including a catheter, drainage bag and one or more indicators configured to measure an attribute relating to the usage of the catheter system and communicate information about the attribute to a network, such as an EMR database. The indicators may include a location indicator, a duration indicator, an elevation indicator, a tamper indicator, a dependent loop indicator, a floor contact indicator, and a patient securement indicator. The system may autonomously detect and record one or more attributes relating to the usage of the catheter system.

Abstract: An air interface plane (AIP) of a radio frequency (RF) aperture includes: a circuit board having a first side and a second side opposite the first side; and a matrix of tapered elements arranged on the first side of the circuit board and secured to the circuit board, the matrix of tapered elements cooperating to at least one of receive or transmit an over-the-air RF signal. Suitably, each tapered element of the matrix has: a central hub extending along a longitudinal axis from a hub base which is proximate to the first side of the circuit board to an apex of the tapered element which is distal from the first side of the first circuit board; and a plurality of arms extending from the central hub at the apex of the tapered element, each of the plurality of arms including a first portion that projects the arm radially away from the longitudinal axis and a second portion that projects the arm longitudinally toward the first side of the circuit board.

Abstract: An ultrasound automatic scanning system according to an embodiment includes an ultrasound probe, a mechanical mechanism, and processing circuitry. The ultrasound probe transmits and receives ultrasonic wave. The mechanical mechanism holds and moves the ultrasound probe while an ultrasonic-wave transmission-reception surface of the ultrasound probe is pointed to a subject. The processing circuitry acquires a distance between a body surface of the subject and the ultrasonic-wave transmission-reception surface of the ultrasound probe based on reflected wave data collected while the ultrasound probe is moved by the mechanical mechanism. The processing circuitry generates, based on information of the distance, locus information of movement of the ultrasound probe when ultrasound scanning is executed on the subject. The mechanical mechanism executes ultrasound scanning on the subject by moving the ultrasound probe based on the locus information generated by the processing circuitry.

Abstract: Systems and methods for applying ultrasound sonication to temporarily disrupt a patient's blood-brain barrier (BBB) include storing threshold values of an acoustic response level, an acoustic response dose and a tissue response dose associated with a target BBB region and its surrounding regions based on anatomical characteristics thereof; causing the ultrasound transducer to transmit one or more pulses/waves; measuring the acoustic response level, the acoustic response dose, and/or the tissue response dose associated with the target BBB region and/or its surrounding regions; comparing the measurement with a corresponding stored threshold value; and operating the transducer based at least in part on the comparison.

Abstract: Apparatus, systems, articles of manufacture, and methods to generate acceptability criteria for autonomous systems plans are disclosed. An example apparatus includes a data compiler to compile data generated by the autonomous system into an autonomous system task dataset, a data encoder to encode the dataset for input into a rule distillation neural network architecture, a model trainer to train the rule distillation neural network architecture, an adaptor to adapt the trained rule distillation neural network architecture to a new input data domain using the autonomous system task dataset, a verifier to generate formally verified acceptability criteria, and an inferer to evaluate a control command, the evaluation resulting in an acceptance or rejection of the command.

Abstract: Piezoelectric osteotomy devices and corresponding systems and methods for removing an acetabular cup or shell from a patient's acetabulum are disclosed. In one embodiment, the piezoelectric osteotomy device includes a piezoelectric element to actuate a cutting tip on an armature. In some such embodiments, the cutting tip may be extended and/or retracted to facilitate cutting of bone around an acetabular cup. The armature may include a fluid output port located proximate the cutting tip to mitigate heat generated by the cutting tip. In one embodiment, the piezoelectric osteotomy device is arranged and configured to provide constant current adjustment.

Abstract: Integrated cartridges for sample homogenization, nucleic acid fragmentation, and nucleic acid detection are disclosed herein. The integrated cartridges include a main housing having a sample well and a detection chamber and a sonication feature coupled to and extending outwardly from the main housing. The sonication feature includes a sonication chamber for receiving a sample fluid. A fluidic path directs the sample fluid from the sample well, to the sonication chamber, and to the detection chamber. Systems for use with the integrated cartridges can include sonotrodes with openings for positioning the sonication feature and/or temperature sensors for monitoring the temperature of the sonication feature. Methods include moving the sample fluid from the sample well to the sonication feature, transmitting ultrasonic energy into the sample fluid, moving the sample fluid from the sonication feature to the detection chamber, and performing a nucleic acid detection assay within the detection chamber.

Abstract: An air interface plane (AIP) of a radio frequency (RF) aperture includes: a circuit board having a first side and a second side opposite the first side; and a matrix of tapered elements arranged on the first side of the circuit board and secured to the circuit board, the matrix of tapered elements cooperating to at least one of receive or transmit an over-the-air RF signal. Suitably, each tapered element of the matrix has: a central hub extending along a longitudinal axis from a hub base which is proximate to the first side of the circuit board to an apex of the tapered element which is distal from the first side of the first circuit board; and a plurality of arms extending from the central hub at the apex of the tapered element, each of the plurality of arms including a first portion that projects the arm radially away from the longitudinal axis and a second portion that projects the arm longitudinally toward the first side of the circuit board.

Abstract: An assembly including: a printed circuit board (PCB) having a first surface and a second surface; at least one energy transmitter mounted on the first surface; at least one cooling element associated with the PCB second surface, wherein the cooling element is configured to cool the at least one energy transmitter via the PCB.

Abstract: Disclosed is a system to assist in a procedure. During the procedure an object may be moved relative to a subject, such as being positioned and/or placed within a subject. The system and related method may be used to assist in displaying and/or determining a pose of the object relative to a subject, such as rigid portions of a subject.

Abstract: The present disclosure relates to methods, apparatuses, and computer programs for processing computed tomography images. Precise segmentation of the left atrium (LA) in computed tomography (CT) images constitutes a crucial preparatory step for catheter ablation in atrial fibrillation (AF). We aim to apply deep convolutional neural networks (DCNNs) to automate the LA detection/segmentation procedure and create a three-dimensional (3D) geometries. The deep learning provides an efficient and accurate way for automatic contouring and LA volume calculation based on the construction of the 3D LA geometry. Non-pulmonary vein (NPV) trigger has been reported as an important predictor of recurrence post atrial fibrillation (AF) ablation. Elimination of NPV triggers can reduce the post-ablation AF recurrence. The deep learning was applied in pre-ablation pulmonary vein computed tomography (PVCT) geometric slices to create a prediction model for NPV triggers in patients with paroxysmal atrial fibrillation (PAF).

Abstract: The invention relates to a probe (110, 210, 310, 410, 510) which has a sealed cooling chamber (140, 240, 340, 440, 540) arranged within a casing (112, 212, 312, 412, 512) of the probe. An interface unit (124, 224, 324, 424, 524) of the probe is at least partially arranged within the cooling chamber or in contact with the cooling chamber. The cooling chamber is at least partially filled with a heat transfer liquid (142, 242, 342, 442, 542).

Abstract: A negative pressure massage device which includes a massage stick, an external negative pressure device and a communication pipe. The massage stick includes a stick body, an air channel in the stick body, a negative pressure connection hole and an air suction opening formed at both ends of the stick body and communicated with the air channel. The external negative pressure device is installed separately from the massage stick and includes a housing and a negative pressure drive/control module. The negative pressure drive/control module includes a controller, a negative pressure generating component, a pressure relief assembly and an air pipe assembly with a negative pressure communication hole formed on the housing. The ends of the communication pipe are communicated with the negative pressure connection hole and the negative pressure communication hole. This disclosure provides various negative pressure massage effects and improves the ease of operation.

Abstract: A method, device and system for ultrasonic delivery and attachment of ligand-receptor based drugs and/or drug carriers and/or image enhancing contrast agents utilizing catch and slip bond mechanisms in a targeted part(s) of the human or animal (patient) body or organs or tissue is described and disclosed. The system includes an acoustic power source coupled to an acoustic transducer with the acoustic transducer placed upon a patient's delivery zone. The acoustic transducer transmits an acoustic field to the target drug delivery and/or imaging zone. A detection probe and/or a probe of an imaging system are placed over or within said delivery zone and the probe is coupled to a sensing/imaging system. A control computer that controls power and wave shape of the acoustic signal generated into the acoustic filed by the acoustic power source and receives data from the sensing/imaging system.

Abstract: An electrosurgical forceps includes a first shaft member including a first inner frame. A first jaw member extends distally from the first inner frame. A first outer housing is supported by the first inner frame. The first inner frame includes a first member stamped from sheet metal. A second shaft member includes a second inner frame. A second jaw member extends distally from the second inner frame. A second outer housing is supported by the second inner frame. The second inner frame includes a second member stamped from sheet metal and a rigid filler member disposed on the second member.

Abstract: A method is provided including disposing midplane treatment electrodes over a superior sagittal sinus, outside and in electrical contact with a skull of a head of a subject identified as at risk of or suffering from Alzheimer's disease. Lateral treatment electrodes are disposed between 1 and 12 cm of a sagittal midplane of the skull. The subject is treated by clearing amyloid beta, by activating control circuitry to apply one or more treatment currents between (a) one or more of the midplane treatment electrodes and (b) one or more of the lateral treatment electrodes; and configure the midplane treatment electrodes as cathodes, and the lateral treatment electrodes as anodes. Other embodiments are also described.

Abstract: A method for covertly creating adverse health effects in a human subject includes generating at least one electromagnetic wave at a frequency within the range of about 300 MHz (megahertz) and about 300 GHz (gigahertz). The at least one electromagnetic energy wave is pulsed at a pulse frequency within a target range of human neural oscillations. At least one ultrasonic audio wave is generated at a frequency greater than about 20 kHz (kilohertz). The at least one audio wave is pulsed at the pulse frequency. Each of the at least one pulsed electromagnetic wave and the at least one ultrasonic audio wave are remotely transmitted to the subject's brain.

Abstract: An energy module is disclosed. The energy module includes a hand-switch circuit, a surgical instrument interface coupled to the hand-switch circuit, and a control circuit coupled to the surgical instrument interface and the hand-switch circuit. The control circuit is configured to control the hand-switch circuit to communicate with a surgical instrument coupled to the hand-switch circuit using a plurality of communication protocols over a single wire. The control circuit is configured to control the hand-switch circuit to supply power to the instrument over the single wire.

Abstract: A therapy apparatus for treating tissue by emission of focused ultrasound waves, including: a creation surface of a pressure field of focused ultrasound waves divided into at least N sectors having segments of asymmetrical concave curve with centres of curvature; centres of curvature asymmetrical to the extent where the centres of curvature are situated at different distances from the plane of symmetry or from at least one of the axis of symmetry and at different depths taken according to the axis of symmetry; the individual axes intersecting between the focal zones and the creation surface or beyond the focal zones such that the beams originating from the sectors intersect to create a focal coverage zone which is off-axis relative to the plane of symmetry or to the axis of symmetry; the sectors of this creation surface creating energy deposit zones with profiles corresponding to the focal coverage zones.

Abstract: Apparatuses and methods for generating therapeutic shock waves. Some embodiments comprise: an acoustic-wave generator configured to emit acoustic waves having at least one frequency between 1 MHz and 1000 MHz; a shock wave housing coupled to the acoustic-wave generator; and a shock wave medium disposed in the shock wave housing; where the apparatus is configured such that if the acoustic-wave generator emits acoustic waves then at least some portion of the acoustic waves will travel through the shock wave medium and form one or more shock waves.

Abstract: The subject matter of the present disclosure generally relates to techniques for neuromodulation of a tissue that include applying energy (e.g., ultrasound energy) into the tissue at multiple regions of interest, concurrently or consecutively. The neuromodulation may result in tissue displacement, which may be observed through changes in one or more molecules of interest.

Abstract: A method of treatment of the human or animal body with noninvasive low energy extracorporeal shockwaves and in particular, to such a method that is utilized for controlling a cascade of biomolecular activity involving a plurality of biomolecular factors, provided to improve function of the treatment portion of the human or animal body.

Abstract: Ultrasonic energy is used for treating degenerative dementia. A focal point of an ultrasonic transducer beam is directed at a target area of the brain to promote removal of substances that accumulate in the interstitial pathways that are at least partially responsible for the degenerative dementia. In one example, the target area of the brain may comprise the hippocampus and the degenerative dementia may be Alzheimer's disease. The ultrasonic beam may stimulate brain tissue at a frequency that corresponds to a naturally occurring deep sleep burst frequency of neurons and subsequent astrocyte activation patterns that drive a convective process responsible for brain solute disposal. For example, the transducer may generate a burst frequency of between 1-4 hertz to stimulate deep sleep brain functions that help remove amyloid plaque.

Abstract: An example skincare device includes a main body having a first side, a second side, an intermediate portion, a groove, a light source, a motor, a temperature control unit, and a user control configured to control one or more of the light source, motor, and temperature control unit. The skincare device can provide heat, cool, light, and/or vibrational therapy to a user's skin.

Abstract: A flue for use with an ultrasonic surgical tip, comprising protrusions or bumps on its inner surface with improved protrusion pattern, density and location. The flue has enhanced cooling effect for the ultrasonic surgical tip.

Abstract: An ultrasound imaging device or probe includes a tip having a heat conducting exterior housing within which an imaging element is positioned. The imaging element is engaged with a heat sink formed of an electrically insulating material that also has high thermal conductivity. The heat sink contacts and extends through and electrically insulating enclosure within which the imaging element is disposed. As a result, the heat generated by the imaging element can be readily conducted to the ambient environment via the heat sink and heat conductive exterior housing while also enabling the imaging element and other electrical components to be electrically insulated from the housing.

Abstract: A catheter-based ultrasound imaging system configured to provide a full circumferential 360-degree view around an intra-vascular/intra-cardiac imaging-catheter-head by generating a three-dimensional view of the tissue surrounding the imaging-head over time. The ultrasound imaging system can also provide tissue-state mapping capability. The evaluation of the vasculature and tissue characteristics include path and depth of lesions during cardiac-interventions such as ablation. The ultrasound imaging system comprises a catheter with a static or rotating sensor array tip supporting continuous circumferential rotation around its axis, connected to an ultrasound module and respective processing machinery allowing ultrafast imaging and a rotary motor that translates radial movements around a longitudinal catheter axis through a rotary torque transmitting part to rotate the sensor array-tip.

Abstract: Methods and systems for treating skin, such as stretch marks through deep tissue tightening with ultrasound are provided. An exemplary method and system comprise a therapeutic ultrasound system configured for providing ultrasound treatment to a shallow tissue region, such as a region comprising an epidermis, a dermis or a deep dermis. In accordance with various exemplary embodiments, a therapeutic ultrasound system can be configured to achieve depth with a conformal selective deposition of ultrasound energy without damaging an intervening tissue. In addition, a therapeutic ultrasound can also be configured in combination with ultrasound imaging or imaging/monitoring capabilities, either separately configured with imaging, therapy and monitoring systems or any level of integration thereof.

Abstract: The present invention is directed to a method for treating a bowel disease in a subject in need thereof, the method comprising inhibiting the activity of neurons of the insular cortex of the subject. Further provided is a system comprising a transcranial stimulation transducing coil for transcranial stimulation configured to provide a series of pulses to neurons of the insular cortex.

Abstract: Provided is a conscious animal ultrasonic neural regulation device, including a pulse signal generation module, a transducer module and a fixing module. The pulse signal generation module is configured to generate a pulse signal with high energy. The ultrasonic transducer module is configured to convert the pulse signal into an ultrasound. The fixing module includes an upper fixing module and a lower fixing module. The upper fixing module is configured to fix the ultrasonic transducer module, and the lower fixing module is configured to be fixed on an animal neural regulation target point. The upper fixing module and the lower fixing module are connected by a connecting component. The conscious animal neural regulation device of the present disclosure can perform accurate ultrasonic stimulation on a cerebral cortex and subcortex of the animal, thereby exploring and verifying the stimulation effect of the ultrasound on the animal, which is easy in operation and convenient in use.

Abstract: A method for sealing a vessel includes supplying electrical energy to an ultrasonic surgical instrument having an end effector and a transducer coupled to the end effector, when the end effector is grasping a vessel, sensing parameters of the vessel when the end effector achieves a predetermined velocity, estimating a size of the vessel based on the sensed parameters, controlling the electrical energy based on maintaining a predetermined initial heating rate of heating the vessel until a predetermined amount of energy corresponding to the estimated size of the vessel has been delivered, and controlling the electrical energy based on a predetermined heating rate curve of heating the vessel after the predetermined amount of energy corresponding to the estimated size of the vessel has been delivered.

Abstract: An ultrasound endoscope includes: an insertion portion; an ultrasound functional unit including an ultrasound transducer; an endoscope functional unit that at least includes an imaging optical system; and a balloon locking portion configured to connect the ultrasound functional unit and the endoscope functional unit, the balloon locking portion having a groove shape that can lock a balloon. A first plane passes, in a direction of a longitudinal axis of the insertion portion, through a first end portion of the ultrasound transducer near the endoscope functional unit, the first plane being perpendicular to the longitudinal axis of the insertion portion, and the first plane is positioned closer to a proximal end than a second plane passing through a second end portion of the balloon locking portion near the ultrasound functional unit, the second plane being perpendicular to the longitudinal axis of the insertion portion.

Abstract: An ultrasound catheter with fluid delivery lumens, fluid evacuation lumens and a light source is used for the treatment of intracerebral hemorrhages. After the catheter is inserted into a blood clot in the brain, a lytic drug can be delivered to the blood clot via the fluid delivery lumens while applying ultrasonic energy to the treatment site. As the blood clot is dissolved, the liquefied blood clot can be removed by evacuation through the fluid evacuation lumens.

Abstract: Among the various aspects of the present disclosure is the provision of a noninvasive and localized brain liquid biopsy using focused ultrasound. Briefly, therefore, the present disclosure is directed to methods and systems to identify brain lesion or tumor characteristics without the need for a solid brain biopsy.

Abstract: A histotripsy therapy system configured for the treatment of tissue is provided, which may include any number of features. Provided herein are systems and methods that provide efficacious non-invasive and minimally invasive therapeutic, diagnostic and research procedures. In particular, provided herein are optimized systems and methods that provide targeted, efficacious histotripsy in a variety of different regions and under a variety of different conditions without causing undesired tissue damage to intervening/non-target tissues or structures.

Abstract: The present disclosure provides a device having a circuit. The circuit includes at least one boost converter receiving power from an energy source, a square wave driver in series with the boost converter, an inductor in series with the square wave driver for converting a square wave to a sinusoidal wave, and a piezoelectric transducer in series with the inductor, the piezoelectric transducer connectable to a load. The device further includes a phase-locked loop coupled to the circuit to determine a resonance frequency of the piezoelectric transducer when the piezoelectric transducer is connected to the load.

Abstract: Vertebral probes for fusionless spinal surgeries and related surgical methods. In some embodiments, the probe may comprise a shaft having one or more tapering portions. Some embodiments may further comprise one or more non-tapering portions. The probe may further comprise a distal tip extending from a shelf or ledge that may allow for penetration of the tip therethrough with a first force and be configured to inhibit further advancement of the probe by requiring a second force substantially greater than the first force to achieve further advancement.

Abstract: Systems, methods, and devices for automatic generation of a stimulation therapy that mimics electrographic activity in the brain at natural seizure termination define a stimulation therapy to be generated by an implanted component of a medical device system and delivered to a subject through identifying data characterizing a patient's seizures, especially at termination. A machine learning model identifies the seizures or seizure types from which to establish a canonical seizure or seizure type, and an algorithm translates the canonical seizure or seizure type into data that can be used to characterize a stimulation therapy. The systems, methods, and devices, include those configured to deliver the stimulation therapy that emulates the canonical seizure or seizure type when the seizure is detected, with the aim of terminating the seizure sooner than it would terminate without intervention.

Abstract: Apparatus and methods for deactivating bronchial nerves extending along the secondary bronchial branches of a mammalian subject to treat asthma and related conditions. An ultrasonic transducer (11) is inserted into the bronchus as, for example, by advancing the distal end of a catheter (10) bearing the transducer into the secondary bronchial section to be treated. The ultrasonic transducer emits circumferential ultrasound so as to heat tissues throughout circular impact volume (13) as, for example, at least about 1 cm3 encompassing the bronchus to a temperature sufficient to inactivate nerve conduction but insufficient to cause rapid ablation or necrosis of the tissues. The treatment can be performed without locating or focusing on individual bronchial nerves. The apparatus and methods utilized for lung tumor ablation.

Abstract: The disclosed technology is directed to a treatment instrument having a vibration generating device and a handle for operation. The vibration generating device comprises a housing and a generator including a transducer disposed within the housing. The transducer generates vibration by using electric energy and a first electric contact disposed on the housing. A connector is rotatable about a predetermined rotational axis with respect to the housing of the generator. A coupler is disposed in the connector and having a second electric contact rotatable about the predetermined rotational axis with respect to the first electric contact in a state in which an electric connection of the second electric contact to the first electric contact is maintained. The connector further includes a conductive member forming a part of an electric path of a current that flows based on an operating input at an operating member provided on the handle.

Abstract: The disclosure relates to a nozzle for a device for the dermo-cosmetic treatment of dark skin spots by cyto-selective cryotherapy comprising a spray jet supplied by a tank of pressurised liquified cryogenic gas. The nozzle comprises an upper ring for connecting to a shell, extended by a central body of which the side wall which narrows downwards has longitudinal openings and delimits a gas expansion chamber communicating with a frustoconical dispersal conduit arranged inside an end piece to be applied to the skin and opening to the outside through a discharge port.

Abstract: Disclosed herein are systems and methods for locating and identifying nerves innervating the wall of arteries such as the renal artery. The present invention identifies areas on vessel walls that are innervated with nerves; provides indication on whether energy is delivered accurately to a targeted nerve; and provides immediate post-procedural assessment of the effect of energy delivered to the nerve. The methods includes evaluating a change in physiological parameters after energy is delivered to an arterial wall; and determining the type of nerve that the energy was directed to (sympathetic or parasympathetic or none) based on the evaluated results. The system includes at least a device for delivering energy to the wall of blood vessel; sensors for detecting physiological signals from a subject; and indicators to display results obtained using said method. Also provided are catheters for performing the mapping and ablating functions.

Abstract: Piezoelectric osteotomy devices and corresponding systems and methods for removing an acetabular cup or shell from a patient's acetabulum are disclosed. In one embodiment, the piezoelectric osteotomy device includes a piezoelectric element to actuate a cutting tip on an armature. In some such embodiments, the cutting tip may be extended and/or retracted to facilitate cutting of bone around an acetabular cup. The armature may include a fluid output port located proximate the cutting tip to mitigate heat generated by the cutting tip. In one embodiment, the piezoelectric osteotomy device is arranged and configured to provide constant current adjustment.

Abstract: In an energy treatment system, a processor temporally detects an electrical property value of an ultrasonic transducer, holds a temporary peak value of the electrical property value, detects an impedance value between the probe electrode and the jaw electrode, and compares the electrical property value and the temporary peak value to determine whether a predetermined condition is satisfied, and whether the impedance value exceeds a predetermined threshold. In response to determining that the electric property value satisfies the predetermined condition and the impedance value is larger than the predetermined threshold, the processor performs at least one of: (i) stopping and (ii) decreasing output from the first power supply, and notifying the determination result.

Abstract: A system includes an endoscope configured for insertion into an internal body cavity and a fluid management system. The fluid management system includes a pump configured to pump fluid through the endoscope into the internal body cavity and a controller configured to determine a pressure within the internal body cavity based upon a current feedback signal received from the pump. A method includes supplying a drive signal to a pump to pump fluid into an internal body cavity, receiving a current feedback signal from the pump, and determining a pressure within the internal body cavity based on the current feedback signal.

Abstract: A method and system perform an ophthalmic procedure on an eye having an optical path from the lens to the retina. An image of at least part of the eye is received in a data processing unit. The image includes the optical path. The data processing unit determines keep out zone(s) and identifies undesirable feature(s) based on the image. The keep out zone(s) include the retina. The data processing unit also selects one of the undesirable feature(s) for removal. At least part of the undesirable feature is outside of the keep out zone(s). Confirmation for removal of the undesirable feature is received in the data processing unit. In response to receiving the confirmation, a control unit controls a laser to perform laser removal the at least the portion of the undesirable feature without targeting any portion of the keep out zone(s).

Abstract: An ultrasonic surgical instrument includes a body, an ultrasonic supported by the body, a shaft extending distally from the body and defining a shaft axis, a waveguide extending distally through the shaft, and an end effector arranged at a distal end of the shaft. The end effector includes an ultrasonic blade coupled to a distal end of the waveguide and having a primary blade treatment surface configured to treat tissue, and a clamp arm coupled to the distal end of the shaft. The shaft and the waveguide are selectively rotatable relative to one another about the shaft axis through a predefined range of angular motion between an assembly state and an operational state. In the assembly state, the clamp arm and the primary blade treatment surface are rotationally offset from one another. In the operational state, the clamp arm and the primary blade treatment surface are rotationally aligned.

Abstract: An electrosurgical apparatus having a feed structure comprising a radiofrequency (RF) channel for conveying RF electromagnetic (EM) radiation from an RF signal generator to a probe and a microwave channel for conveying microwave EM radiation from a microwave signal generator to the probe, wherein the RF channel and microwave channel comprise physically separate signal pathways, wherein the feed structure includes a combining circuit having an input connected to the signal pathway on the RF channel, another input connected to the signal pathway on the microwave channel, and an output connected to a common signal pathway for conveying the RE EM radiation and EM radiation separately or simultaneously to the probe, and wherein the microwave channel includes a waveguide isolator connected to isolate the signal pathway on the microwave channel from the RF EM radiation.