With Piston Or Plunger For Expelling Material From Body Or Injector Reservoir Patents (Class 604/218)
  • Patent number: 11931123
    Abstract: A port placement guide may include a base, a member, and at least one tracking element. The base can be configured to couple to a surface of a patient at a preliminary port location for a robotic arm. The member can be coupled to the base and can comprise a first end and a second end opposite the first end. The at least one tracking element can be coupled to the member and can be configured to allow tracking of the member relative to the preliminary port location.
    Type: Grant
    Filed: June 17, 2021
    Date of Patent: March 19, 2024
    Assignee: Verb Surgical Inc.
    Inventors: Kent Anderson, Katherine Anderson
  • Patent number: 11896807
    Abstract: Disclosed are plunger assemblies including various convertible plungers and methods of making the same. Each plunger assembly is configured for disposition within a barrel of a medical container, e.g., a syringe, and displaced within the barrel from an engagement position to a release position. The engagement position is configured to provide a compression seal between a storage sealing section of the plunger and an inner wall of the syringe barrel. In the release position, the compression seal is reduced or eliminated. Also disclosed are methods for making convertible plungers and assembling them into syringes, e.g., pre-filled syringes.
    Type: Grant
    Filed: February 16, 2021
    Date of Patent: February 13, 2024
    Assignee: SIO2 MATERIAL PRODUCTS, INC
    Inventors: Brian Russell Lilly, Kenneth Wade Kelly, Joseph W. Rogers, Jean-Pierre Giraud, Bruce Rabinne, Herve Pichot, Benjamin Hunt, Zachary Dean Freeman, Dalton Roe, Robert S. Abrams
  • Patent number: 11890430
    Abstract: A medical dispensing device which includes a catheter, an applicator tip at a distal end of the catheter, the catheter and the applicator tip defining a lumen having a longitudinal axis and a distal opening, a plunger in the lumen and movable along the longitudinal axis, and a plurality of elements in the lumen proximal to the distal opening and distal to the plunger, the plurality of elements stacked along the longitudinal axis for dispersement of one element at a time through the distal opening via a force applied by the plunger.
    Type: Grant
    Filed: December 16, 2022
    Date of Patent: February 6, 2024
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Joseph W. King, Gonzalo Jose Saenz Villalobos, John T. Favreau, Lauren S. Lydecker
  • Patent number: 11878153
    Abstract: The present invention relates to a medicament delivery device comprising a housing, a compartment inside said housing for positioning a medicament container, an injection needle arranged to said housing, being connectable to said medicament container for delivering a dose of medicament, a manually operated activation mechanism for activating said device, an actuation mechanism operably connected to said activation mechanism and arranged to, upon activation of said activation mechanism, extend said injection needle from a first position inside said housing to a second position wherein a penetration of a patient is performed, a plunger rod arranged in said housing capable of acting on said medicament container for delivering a dose of medicament through said injection needle, a driver capable of acting on said plunger rod for delivering a dose of medicament.
    Type: Grant
    Filed: November 4, 2020
    Date of Patent: January 23, 2024
    Assignee: SHL MEDICAL AG
    Inventors: Eugen Koch, Cheng-Jung Yang, Laura Scholze
  • Patent number: 11878148
    Abstract: Syringe assemblies are provided including a partially pre-filled syringe barrel and a plunger rod that incorporates one or more retention elements on the plunger rod that prevents solution from entering a non-sterile area of the syringe when the plunger rod is pulled back. Methods to manufacture a sterilized partially-filled pre-fill syringe assembly are also disclosed.
    Type: Grant
    Filed: June 23, 2020
    Date of Patent: January 23, 2024
    Assignee: Becton, Dickinson and Company
    Inventors: Paul P. Marici, Xiaoyu Sun, Jonathan Marek Zalot, Youstina Matta
  • Patent number: 11872380
    Abstract: The present invention relates to a medicament delivery device for delivering a number of predetermined amounts of medicament, comprising a body having a proximal and an opposite distal end and extending along a longitudinal axis (L); a medicament container (20) arranged inside said body; a driving mechanism arranged inside said body and configured to act on said medicament container; a manually movable activation member (102) arranged on the distal end the body; a biased actuator member (64) arranged to be movable along the longitudinal axis and through the manually movable activation member (102), said biased actuator member being configured to protrude a predetermined distance from the distal end of the manually movable activation member and configured to interact with said driving mechanism when the biased actuator member is displaced said predetermined distance towards the proximal end of the body for delivering a predetermined amount of medicament; and an actuator guide member (90) arranged in the body a
    Type: Grant
    Filed: November 17, 2020
    Date of Patent: January 16, 2024
    Assignee: SHL MEDICAL AG
    Inventor: Natalia Chuvashova
  • Patent number: 11857995
    Abstract: A method of making a two-component piston, the two-component piston including a piston cover as the first component and a piston body as the second component. The piston cover is arranged adjacent to the piston body and is configured to be moved relative to the piston body.
    Type: Grant
    Filed: May 31, 2022
    Date of Patent: January 2, 2024
    Assignee: MEDMIX SWITZERLAND AG
    Inventors: Manfred Obrist, Philipp Seiler, Renato Brunner
  • Patent number: 11857208
    Abstract: An aspiration device can be used to aspirate an obstruction from a blood vessel. The aspiration device is configured to allow controlled one-handed aspiration yet maintain a syringe plunger feel of vacuum. The aspiration device also allows one-handed injection to empty the device when needed. Furthermore, mechanisms enable one-handed locking of a plunger position of the device to maintain vacuum when the user releases the device.
    Type: Grant
    Filed: March 5, 2021
    Date of Patent: January 2, 2024
    Assignee: Silk Road Medical, Inc.
    Inventors: Michi E. Garrison, Sieu T. Duong
  • Patent number: 11813436
    Abstract: Auto-injector for administering a dose of a liquid medicament includes a housing to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end with an orifice to apply against an injection site. A spring means, upon activation, can push the needle from inside the housing through the orifice and past the proximal end, operate the syringe to supply the dose of medicament, and retract the syringe with the needle after delivering the medicament. An activating means can lock the spring means in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring means for injection.
    Type: Grant
    Filed: May 8, 2023
    Date of Patent: November 14, 2023
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Matthew Ekman, Yannick Hourmand, Timothy Donald Barrow-Williams
  • Patent number: 11779740
    Abstract: Microarray applicator (10000), a method of using the same and a kit. The microarray applicator comprising a housing (2000), a microarray holder (8100) and a plunger (7000). The plunger comprising a first ridge (7310) and a second ridge (7320), both engagable to a notch (2320). Microarray applicator does not uses springs or pre-biased mechanisms to reduce costs.
    Type: Grant
    Filed: December 4, 2018
    Date of Patent: October 10, 2023
    Assignee: Kindeva Drug Delivery L.P.
    Inventors: David J. Wirtanen, Kevin L. Puckett, James L. Schug, David J. White
  • Patent number: 11751859
    Abstract: Medical devices for delivering compositions or medical articles to a patient are disclosed. The medical plug delivery devices can include a fluid delivery device (e.g., a syringe), a frame, and a rotatable magazine. The rotatable magazine can include a plurality of chambers that each hold a composition or a medical article (e.g., a medical plug). By rotating the rotatable magazine relative to the frame, material within the chambers of the rotatable magazine can be sequentially deployed to a patient.
    Type: Grant
    Filed: March 15, 2021
    Date of Patent: September 12, 2023
    Assignee: Merit Medical Systems, Inc.
    Inventors: Fred Lampropoulos, Jim Mottola, Richard P. Jenkins, Gregory R. McArthur, Kenneth Sykes, Christopher Cindrich, Mark Garcia
  • Patent number: 11744755
    Abstract: Modules for housing electronic and electromechanical medical equipment including a system to measure and record administration of one or more IV medications or fluids for IV administration.
    Type: Grant
    Filed: January 20, 2023
    Date of Patent: September 5, 2023
    Assignee: Augustine Biomedical + Design, LLC
    Inventors: Scott D. Augustine, Susan D. Augustine, Garrett J. Augustine, Brent M. Augustine, Ryan S. Augustine, Randall C. Arnold
  • Patent number: 11744928
    Abstract: A syringe receptacle device for collecting a liquid from an extraction device, a cylindrical barrel, and a plunger. The barrel has an inner circumferential surface that extends between opposite first and second ends. The first end of the barrel is adapted to be removably coupled to the extraction device. The plunger is slidably coupled to the barrel and includes a plunger head and an actuating rod. The plunger head is frictionally engaged with the inner circumferential surface of the barrel. The actuating rod is fixedly attached to the plunger head and extends out through the second end of the barrel.
    Type: Grant
    Filed: March 6, 2020
    Date of Patent: September 5, 2023
    Inventor: Maryam Berri
  • Patent number: 11730893
    Abstract: An injection device, comprising an interface for mounting on a syringe body, the interface comprising an internal passage delimited by an inner wall, a needle and a sheath for receiving said needle, said sheath comprising an outer wall provided with a contact portion of said sheath in contact with an attachment portion of the inner wall of the interface, wherein the contact portion comprises a first bead and in that the attachment portion comprises a second bead, the first and second beads each forming a ring protruding respectively on the contact portion and the attachment portion, the first bead being in contact with the second bead.
    Type: Grant
    Filed: May 17, 2017
    Date of Patent: August 22, 2023
    Assignee: Numedico Technologies (IP) Pty Ltd.
    Inventor: Emmanuel Mastorakis
  • Patent number: 11724037
    Abstract: An assembly for a container to be filled with a pharmaceutical drug is provided. The assembly includes a first component and a second component. The first component has at least one electronic device fully embedded therein, a first end provided with a first engagement feature and an opposing second end. The second component has a second engagement feature configured to engage the first engagement feature of the first component.
    Type: Grant
    Filed: June 6, 2018
    Date of Patent: August 15, 2023
    Assignee: West Pharmaceutical Services, Inc.
    Inventors: Kerry Drake, Patrick Dowling, Michael Sullivan, Jason Krizan
  • Patent number: 11717614
    Abstract: A syringe for a fluid delivery system includes a pressure jacket having a distal end, a proximal end, and a throughbore therebetween. The syringe further includes a rolling diaphragm having a proximal end with an end wall for engaging a plunger, a distal end received within the throughbore of the pressure jacket. The distal end of the rolling diaphragm has a nozzle and a sidewall extending between the proximal end and the distal end of the rolling diaphragm along a longitudinal axis. At least a portion of one of the sidewall and the end wall has non-uniform thickness. At least a portion of the sidewall is flexible and rolls upon itself when acted upon by the plunger such that an outer surface of the sidewall at a folding region is folded in a radially inward direction as the plunger is advanced from the proximal end to the distal end of the rolling diaphragm.
    Type: Grant
    Filed: March 9, 2020
    Date of Patent: August 8, 2023
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Dave Berry, Kevin P. Cowan, Martin J. Gibler, Michael A. Spohn
  • Patent number: 11701469
    Abstract: Devices and methods are disclosed that provide a syringe actuator device for use in the distention and irrigation of a body conduit before the use in a medical procedure such as a coronary bypass graft procedure. The device can be retrofit to a syringe by attaching it to the cap of the plunger and engaged to automatically apply pressure to fluid in the syringe. In some embodiments, elastic bands attached to the device are easily engaged or removed from a syringe during a procedure to limit the pressure on the syringe to various levels. The device may be overridden by an operator pushing on the plunger of the syringe as in normal syringe operation.
    Type: Grant
    Filed: April 27, 2020
    Date of Patent: July 18, 2023
    Inventor: Matthew John Petrides
  • Patent number: 11684725
    Abstract: A disposable syringe for use with a pneumatic driver. The syringe has an elongated barrel with a cap secured to the proximal end that has a through bore. A filter is secured to the cap interior of the barrel that covers an opening in the through bore interior of the barrel. The pneumatic driver includes a source of pressurized air; a support for receiving and locating the syringe; and a supply block configured to receive pressurized air from the source and having an outlet for delivery of pressurized air. The supply block is movable between a first position spaced apart from the cap of the syringe and a second position in contact with the cap with fluid communication being established between the outlet of the supply block and the through-bore in the cap.
    Type: Grant
    Filed: December 3, 2019
    Date of Patent: June 27, 2023
    Assignee: Fenwal, Inc.
    Inventor: Robert Brown
  • Patent number: 11679202
    Abstract: An injector comprises a cylindrical barrel, a movable body housed in the barrel, and a plunger coming into separable contact with the movable body. The movable body includes a main body having an outer diameter smaller than an inner diameter of the barrel, a disk-shaped seal body disposed on the main body and including an outer circumferential end brought into close contact with an inner circumferential surface of the barrel, and at least one projecting portion projecting from the main body toward the inner circumferential surface of the barrel. A distance from a central axis of the movable body to a leading end of the at least one projecting portion is smaller than a half of an outer diameter of the seal body.
    Type: Grant
    Filed: June 20, 2019
    Date of Patent: June 20, 2023
    Assignee: KABUSHIKI KAISHA SHOFU
    Inventors: Hideto Kasaba, Hiroyuki Kobayashi, Hiroyuki Shioi, Hiroshi Yaana, Toshiyuki Nakatsuka, Yukihiro Ogawa, Hisako Tokura
  • Patent number: 11679205
    Abstract: A digital syringe is used with conventional polymer disposable syringe construction to be practical in the medical environment. Errors associated with the larger volumes of the syringes (which exacerbate minor errors in plunger position) and the flexibility and dimensional variations of the polymer plungers are accommodated by direct measurement of the syringe plunger position rather than indirect measurement of motor position and inference of syringe plunger position. This direct measurement eliminates mechanical tolerances (“stack up”) in the motor, gear train, and lead screw on plunger movement, an effect exacerbated by flexibility of the plunger and changes in syringe resistance and medicament viscosity, for example, with different medicaments or when the syringe is refrigerated. The digital syringe may be combined with the motor unit to provide additional versatility.
    Type: Grant
    Filed: March 10, 2020
    Date of Patent: June 20, 2023
    Assignee: Zyno Medical LLC
    Inventors: Chao Young Lee, Zhenhua Mao, Mei Zhang, Frederick Lee
  • Patent number: 11672916
    Abstract: A supplementary device configured to be releasably attached to a distal end of a drug delivery device. The supplementary device comprising primary electronics, a non-contact acceleration sensor and a low power processor. The non-contact acceleration sensor is directed towards a proximal end of the drug delivery device and the low power processor is configured to: receive the signals output from the non-contact acceleration sensor; determine based on the signals that an outer needle cap of the drug delivery device has been removed; and in response to determining that an outer needle cap of the drug delivery device has been removed, send a wake-up signal to the primary electronics of the supplementary device.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: June 13, 2023
    Assignee: Sanofi
    Inventor: Michael Helmer
  • Patent number: 11660398
    Abstract: The present invention relates to a stopper for an injector for delivery of a pharmaceutical composition and to an injector with the stopper. The stopper has a stopper body with an actuating surface opposite an outlet surface, an axial length between the actuating surface and the outlet surface, and a transverse diameter, which stopper body defines an access diameter, the stopper at an axial location from the actuating surface comprising a deformable sealing element surrounding the stopper body and having an outer diameter, which is larger than the transverse diameter, which deformable sealing element is made from a thermoplastic elastomer and has an axial extension in the range of 5% and 95% of the axial length of the stopper body, and the stopper comprising a cavity at the axial location of the deformable sealing element, the cavity having a lateral extension larger than the access diameter of the stopper body.
    Type: Grant
    Filed: March 27, 2019
    Date of Patent: May 30, 2023
    Assignee: INJECTO GROUP A/S
    Inventor: Mikael Hetting
  • Patent number: 11654046
    Abstract: A liquid formulation of an ophthalmic drug in a pharmaceutical package, for example a syringe, cartridge, or vial, made in part or in whole of a thermoplastic polymer, coated on the interior with a tie coating or layer, a barrier coating or layer, a pH protective coating or layer, and optionally a lubricity coating or layer.
    Type: Grant
    Filed: November 18, 2016
    Date of Patent: May 23, 2023
    Assignee: SIO2 MEDICAL PRODUCTS, INC.
    Inventors: Christopher Weikart, Murray Stephen Bennett, Jean-Pierre Giraud
  • Patent number: 11654240
    Abstract: Medical devices capable of filling liquid into a syringe barrel while evacuating any air from the syringe are described. An exemplary medical device includes a syringe barrel having a tapered sidewall portion for permitting air to vent from the chamber and preventing liquid from exiting the chamber, a plunger rod, and stopper. Another exemplary medical device includes a syringe barrel having a plurality of air venting grooves associated with the sidewall of the barrel, a plunger rod and stopper. Also described is a medical device including a syringe barrel, plunger rod and stopper having a porous plug. Described is a medical device including a syringe barrel having a plurality of air venting grooves associated with the sidewall of the barrel and a porous membrane disposed over the air venting grooves, a plunger rod and stopper. Methods for filling a syringe barrel with a liquid are also provided.
    Type: Grant
    Filed: May 16, 2019
    Date of Patent: May 23, 2023
    Assignee: Becton, Dickinson and Company
    Inventor: Yiping Ma
  • Patent number: 11633543
    Abstract: In a locking device for locking a plunger rod a plunger rod locking portion is provided for locking a plunger rod of a syringe after use and preventing re-use of the syringe. A chamber is formed inside the plunger rod locking portion for receiving the disc-shaped proximal end of the plunger rod after use of the syringe. The plunger rod locking portion comprises at least one positive locking device configured to positively lock the axial position of the plunger rod by positive-fit engagement with the disc-shaped proximal end of the plunger rod and retain the disc-shaped proximal end of the plunger rod inside the chamber. The locking device provides the functionality of a tamper-evident plunger rod locking device once a dose of medication has been injected by pushing the plunger rod forward, for preventing inadvertent re-use of the syringe.
    Type: Grant
    Filed: September 18, 2020
    Date of Patent: April 25, 2023
    Assignee: KAISHA PACKAGING PRIVATE LIMITED
    Inventor: Rishad Kairus Dadachanji
  • Patent number: 11623813
    Abstract: There is provided a syringe filled with a resin composition which prevents a barrel cap from being detached due to temperature change during storage or during transportation, a production method thereof, and a storage method thereof. This syringe filled with the resin composition includes a syringe having a syringe barrel, a resin composition filling the syringe barrel, a plunger inserted in the syringe barrel, a barrel cap blocking an opening of the syringe barrel, and a spatial part between the plunger and the barrel cap in the syringe barrel. The pressure of the spatial part in a frozen state is 50 kPa to 92 kPa.
    Type: Grant
    Filed: February 6, 2020
    Date of Patent: April 11, 2023
    Assignee: NAMICS CORPORATION
    Inventors: Hiroki Myodo, Masaaki Hoshiyama
  • Patent number: 11607159
    Abstract: A bodily-fluid transfer device includes a housing, a pre-sample reservoir, and an actuator. The housing defines an inner volume between a substantially open proximal end portion and a distal end portion that includes a port couplable to a lumen-defining device. The pre-sample reservoir is fluidically couplable to the port to receive a first volume of bodily fluid. The actuator is at least partially disposed in the inner volume and has a proximal end portion that includes an engagement portion and a distal end portion that includes a sealing member. The engagement portion is configured to allow a user to selectively move the actuator between a first configuration such that bodily fluid can flow from the port to the pre-sample reservoir, and a second configuration such that bodily fluid can flow from the port to a sample reservoir defined at least in part by the sealing member and the housing.
    Type: Grant
    Filed: March 31, 2022
    Date of Patent: March 21, 2023
    Assignee: Magnolia Medical Technologies, Inc.
    Inventors: Gregory J. Bullington, Richard G. Patton, Shan E. Gaw
  • Patent number: 11590517
    Abstract: An applicator for a syringe is provided that includes a hub configured to be disposed at least partially within a nozzle of the syringe and defining a fluid passage therethrough, with one or barbs on the hub that frictionally and sealingly engage an interior of the nozzle in a manner minimizing void space associated with waste of deliverable material, and an applicator tip extending distally from the hub. The barb(s) may have varying diameters in order to enable the applicator to be engaged and utilized with syringes having different diameter nozzles. Further the fluid passage through the hub and applicator tip is dimensioned to minimize the volume of material that is retained within the applicator after use, thereby increasing the volume of material that can dispensed from the syringe for use in a procedure or procedures and minimize waste.
    Type: Grant
    Filed: September 1, 2022
    Date of Patent: February 28, 2023
    Assignee: INTER-MED, INC.
    Inventors: John Baeten, Alexander D. Johnson
  • Patent number: 11577027
    Abstract: A plunger (1) for a medical delivery device comprises: a rod element (2) having a distal end (22) and a proximal end, and a stopper (3) mounted to the rod element (2) at its distal end (22). The rod element (2) has a first form fit structure (24) and the stopper (3) has a second form fit structure (31). The stopper (3) is locked to the rod element (2) by the first form fit structure (24) of the rod element (2) and the second form fit structure (31) of the stopper (3) engaging each other.
    Type: Grant
    Filed: July 9, 2019
    Date of Patent: February 14, 2023
    Assignee: HOFFMANN-LA ROCHE INC.
    Inventors: Maxime Gaillot, Alan Dwyer, Pascal Launois, Julian McDonnell, Eoin Connaughton, Mark Digby Teucher, Jonathan Paul Ridley
  • Patent number: 11571520
    Abstract: A prefilled syringe includes a syringe body filled with a medical fluid, which has a nozzle at a front side, the nozzle being closed with a cap, and which is closed at a rear side with a displaceable plunger; and a plunger rod that can be inserted into the syringe body via the rear side. The plunger rod has a connecting portion at a front side, via whi9ch the plunger rod can be connected to the plunger. At least three annular elements, which extend at least in some sections about a longitudinal axis of the rod, are arranged on a rear side of the connecting portion on the plunger rod in such a manner that they are located in the syringe body when the plunger rod is fully connected to the plunger. The three annular elements support a coaxial connection of the rod to the plunger positioned in the syringe.
    Type: Grant
    Filed: January 27, 2020
    Date of Patent: February 7, 2023
    Assignee: Fresenius Kabi Austria GmbH
    Inventors: Wolfgang Baldauf, Jörg Heinrich, Christoph Zauner
  • Patent number: 11547392
    Abstract: A biological sample collection system can include (i) a sample collection vessel having an opening for receiving a biological sample, (ii) a selectively movable valve comprising a core and a collar disposed about the core, and (iii) a sealing cap coupled to the collar and comprising a reagent chamber for storing a measure of sample preservation reagent. The sealing cap is configured to associate—and form a fluid tight connection—with the sample collection vessel such that associating the sealing cap with the sample collection vessel causes a physical rearrangement of the core relative to the collar such that a fluid vent associated with the core is moved into fluid communication with the reagent chamber, thereby permitting sample preservation reagent to pass from the regent chamber to the sample collection vessel.
    Type: Grant
    Filed: February 18, 2021
    Date of Patent: January 10, 2023
    Assignee: Spectrum Solutions L.L.C.
    Inventor: Neil Jeremy Johnson
  • Patent number: 11547794
    Abstract: A plunger for use with a syringe has a plunger body with a proximal end, a distal end, and a circumferential sidewall extending between the proximal end and the distal end along a plunger longitudinal axis. The plunger further has at least one resiliently deflectable retaining member having a first segment attached to the plunger body and a second segment protruding toward the distal end of the plunger body and deflectable relative to the first segment. The plunger further has at least one actuation member associated with the at least one resiliently deflectable retaining member. The at least one actuation member interacts with a piston to deflect the at least one resiliently deflectable retaining member upon rotation of the plunger relative to the piston. The plunger is engageable with the piston regardless of a rotational orientation of the piston relative to the plunger.
    Type: Grant
    Filed: December 16, 2019
    Date of Patent: January 10, 2023
    Assignee: Bayer Healthcare LLC
    Inventors: Michael Swantner, Richard Seman, Barry Tucker, Arthur Uber, III, Kevin Cowan, James Dedig, Christopher Capone, Jaroslaw Wlodarczyk
  • Patent number: 11541177
    Abstract: A method of adapting an auto injector configured to actuate a prefilled syringe, the auto injector having a biasing member having a spring constant, the prefilled syringe being filled with a volume of therapeutic fluid, the prefilled syringe including a barrel, stopper, and a needle, the stopper having a path of travel, the biasing member arranged to move the stopper along the path of travel. An auto injector having an injection spring adapted to an aged prefilled syringe.
    Type: Grant
    Filed: September 19, 2019
    Date of Patent: January 3, 2023
    Assignee: Teva Pharmaceuticals International GmbH
    Inventors: Paul Andrew Christopher Gibson, Edward Andrew Cummings
  • Patent number: 11517679
    Abstract: A syringe system includes a syringe and a pressurization device for a syringe. The pressurization device for a syringe is configured so that the plunger advances by a forward rotation of the plunger, and the plunger retracts by a reverse rotation of the plunger. The plunger is advanceable by pressing the gasket at the time of the forward rotation and is retractable with respect to the barrel without pulling the gasket in the proximal end direction at the time of the reverse rotation.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: December 6, 2022
    Assignee: TERUMO KABUSHIKT KAISHA
    Inventors: Hiroaki Takahashi, Hitoshi Okihara, Yuki Kobarai
  • Patent number: 11517683
    Abstract: A device for positioning a needle tip to a desired location by signaling pressure change is provided. The device includes a barrel, a piston, a biasing element, and a plunger. The barrel defines a reservoir, and it includes a distal end connectable to a puncturing apparatus. The plunger is slidably engaged with the piston, and both are movable within the reservoir. The biasing element connects the plunger and the piston, and its change in length corresponds to the relative position of the plunger and piston. In operation, the piston is at a first position relative to the plunger when the biasing element is at a first length. The piston later moves to a second relative position in response to the biasing element's change of the length resulting from a pressure change inside the reservoir when the puncturing apparatus reaches a location of a mass. The position's change of the piston is visually detectable.
    Type: Grant
    Filed: March 9, 2018
    Date of Patent: December 6, 2022
    Inventor: Li-Yu Lin
  • Patent number: 11511044
    Abstract: Syringe assemblies are described herein. A syringe assembly includes an assembly housing, a first syringe, a second syringe, and a connecting gear. The first syringe is disposed within the assembly housing. Each plunger is movable within the respective syringe cavity and defines a respective chamber in the respective syringe cavity, wherein the respective chamber is in fluid communication with the respective syringe port, the respective plunger comprising a respective gear rack extending longitudinally along the respective plunger. The connecting gear is rotatably coupled to the assembly housing. The connecting gear is configured to be in meshed engagement with at least one of the first gear rack and the second gear rack of the syringes.
    Type: Grant
    Filed: September 16, 2019
    Date of Patent: November 29, 2022
    Assignee: CareFusion 303, Inc.
    Inventors: Todd Oda, George Mansour, Eugene Mason, Tomas Frausto, Dylan Beyhl
  • Patent number: 11511046
    Abstract: A method of assembling a drug delivery device, comprising the steps of: inserting a piston rod in a nut portion of a cartridge assembly and rotating the piston rod until the piston rod distal end engages the cartridge piston, mounting a drive member on the piston rod in a rota-tional position being closest to a pre-determined rotational position, and rotating the drive member to the pre-determined rotational position.
    Type: Grant
    Filed: October 9, 2018
    Date of Patent: November 29, 2022
    Assignee: Novo Nordisk A/S
    Inventors: Daniel Knudsen, Jeppe Marckmann
  • Patent number: 11504480
    Abstract: A data collection apparatus comprises a camera configured to obtain first and second recordings of at least a portion of a medicament delivery device, said portion including a first component and a second component, the first component being configured to move relative to the second component as medicament is expelled from the medicament delivery device. The data collection apparatus also comprises a processing arrangement configured to determine, from said first and second recordings, positions in the first and second recordings of the first component relative to the second component, and determine an amount of medicament that has been expelled by the medicament delivery device by comparing the position, in the first recording, of the first component relative to the second component with a position, in the second recording, of the first component relative to the second component.
    Type: Grant
    Filed: December 12, 2017
    Date of Patent: November 22, 2022
    Inventors: Michael Schabbach, Beate Franke
  • Patent number: 11498094
    Abstract: A method of making a two-component piston, the two-component piston including a piston cover as the first component and a piston body as the second component. The piston cover is arranged adjacent to the piston body and is configured to be moved relative to the piston body.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: November 15, 2022
    Assignee: MEDMIX SWITZERLAND AG
    Inventors: Manfred Obrist, Philipp Seiler, Renato Brunner
  • Patent number: 11478585
    Abstract: Provided is a syringe gasket including a first member, and a second member connected to the first member and coupled to a plunger rod of a syringe. The first member includes a top face contacting with the liquid, and a first side circumferential face that faces an inner circumferential face of a barrel of the syringe. The first side circumferential face has, at an end portion thereof close to the second member, a ring-like trimmed face. An inert film is laminated on the top face and the portion of the first side circumferential face other than the ring-like trimmed face. The second member includes a second side circumferential face that faces the inner circumferential face of the barrel, and a ring-like protruding portion that projects outward in the radial direction from the second side circumferential face. The ring-like protruding portion at least partially covers the ring-like trimmed face.
    Type: Grant
    Filed: May 29, 2018
    Date of Patent: October 25, 2022
    Assignee: SUMITOMO RUBBER INDUSTRIES, LTD.
    Inventors: Pederiva Marco, Protti Roberto
  • Patent number: 11473932
    Abstract: A position encoder arrangement is configured to detect the position of a movable source based on a source field, which is a magnetic field or an electric field, emitted by the source. The position encoder arrangement includes a number of sensor elements that are evenly distributed and each is configured to provide a sensor value based on the source field at the sensor element's location. The arrangement further includes an evaluation unit that is configured to determine a fine position value for the position of the movable source, and to determine from the sensor values a trustworthiness of the fine position value and/or an error flag indicating whether a failure status of the position encoder arrangement is present.
    Type: Grant
    Filed: May 16, 2019
    Date of Patent: October 18, 2022
    Assignee: AMS AG
    Inventors: Stephan Michelitsch, Gerhard Oberhoffner
  • Patent number: 11446672
    Abstract: Described are exemplary embodiments of a grasping mechanism for a powered, handheld positive displacement pipette, the grasping mechanism configured to grasp and releasably retain the piston head of a syringe that is usable with the pipette.
    Type: Grant
    Filed: October 25, 2019
    Date of Patent: September 20, 2022
    Assignee: Mettler-Toledo Rainin, LLC
    Inventors: Michael McNaul, Richard Hill, Stephen Grimwade, Michael Fairs, Vasanthan Mani, Cyril Fernandez
  • Patent number: 11439757
    Abstract: The present disclosure relates to a medical delivery device that includes a barrel having an inner surface, a plunger rod having a distal end inserted within the barrel, and a stopper attached to the distal end of the plunger rod and contacting at least a portion of the inner surface of the barrel. In at least one embodiment, the inner surface is hydrophilic. The stopper may include an elastomeric body, one or more fluoropolymer layers, and two or more ribs laminated with the one or more fluoropolymer layers. In some embodiments, the contact width between at least one rib having a sealing surface and the portion of the inner surface of the barrel measured at a compressibility of greater than about 7.9% of the stopper is less than about 1.0 mm.
    Type: Grant
    Filed: October 3, 2019
    Date of Patent: September 13, 2022
    Assignee: W. L. Gore & Associates, Inc.
    Inventors: Greg Rusch, Robert C. Basham
  • Patent number: 11419983
    Abstract: A transport assembly for shipping components of a medicament delivery device to final assembly is presented, where the transport assembly has a plunger rod, a first resilient member configured to bias the plunger rod, an elongated plunger rod holder configured to receive the plunger rod, a transport securing sleeve configured to receive a portion of the plunger rod holder, and configured to move axially from a first position relative to the plunger rod holder in which the transport securing sleeve prevents the plunger rod holder to disengage from the plunger rod to a second position located distally relative to the first position, enabling disengagement of the plunger rod holder from the plunger rod, a rear end cap, and a second resilient member configured to bear against the rear end cap and configured to bias the transport securing sleeve in the proximal direction away from the second position.
    Type: Grant
    Filed: July 2, 2018
    Date of Patent: August 23, 2022
    Assignee: SHL MEDICAL AG
    Inventors: Erika André, Pär Leander, Linda Odelberg, Anders Holmqvist
  • Patent number: 11413406
    Abstract: A tamper evident assembly for retaining a plunger and/or piston within a barrel of a syringe comprises an elongated tether disposed in an operative attachment and position on the syringe. When operatively attached, a connector assembly adjustably and fixedly interconnects the tether to an exterior of the barrel of the syringe concurrently to one end of the tether, and with a retaining member associated with the opposite end of the tether disposed in a removal restrictive relation to the plunger and/or piston, on the interior of the barrel. Movable adjustment of the tether relative to the connector assembly defines a retaining segment which can be disposed into a fixed length and taut orientation, between the ends of the tether, to further define the operative attachment or position.
    Type: Grant
    Filed: October 11, 2019
    Date of Patent: August 16, 2022
    Inventors: Jonathan J. Vitello, Timothy Brandon Hunt, Robert Banik
  • Patent number: 11400217
    Abstract: According to the invention, an auto-injector for administering a dose of a liquid medicament (M) comprises of a substantially cylindrical housing arranged to contain a pre-filled syringe filled with the medicament (M), a needle shroud slidably arranged with respect to the housing and adapted to rest on the skin of a patient receiving an injection, a releasable drive means arranged within the housing that is capable of, upon release, translating the needle shroud in a proximal direction (P) towards a safe position (PS) and a rotating collar rotatably arranged within the housing. The needle shroud in the safe position (PS) surrounds the injection needle after the injection has been carried out. The rotating collar engages the needle shroud in a manner that forces the rotating collar to rotate within the housing when the needle shroud is translated in the proximal direction (P).
    Type: Grant
    Filed: March 28, 2022
    Date of Patent: August 2, 2022
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Yannick Hourmand, Timothy Donald Barrow-Williams, Matthew Ekman
  • Patent number: 11389590
    Abstract: The present disclosure relates to a administration assembly for a medicament delivery device, comprising: an elongated tubular delivery member cover (7), a cartridge holder (11) configured to be received by the delivery member cover (7) and configured to accommodate a medicament cartridge (31), the cartridge holder (11) having a radially flexible and radially inwards extending cartridge blocking protrusion (11b) configured to prevent the medicament cartridge (31) from moving proximally until being subjected to a proximally directed force larger than a threshold value, a needle assembly (13) comprising a double-edged needle having a proximally extending needle portion (13a) and a distally extending needle portion (13b), wherein the needle assembly (13) is configured to be assembled with the cartridge holder (11) so that the distally extending needle portion (13b) extends into the cartridge holder (11), and an administration mechanism including a plunger rod (27) configured to be proximally biased, wherein the
    Type: Grant
    Filed: March 26, 2018
    Date of Patent: July 19, 2022
    Assignee: SHL MEDICAL AG
    Inventor: Oscar Alexandersson
  • Patent number: 11376369
    Abstract: A syringe including a barrel, a plunger moveably arranged within said barrel, and a plunger rod for driving said plunger. A first engagement member is arranged at the plunger rod, such that a longitudinal movement of the plunger rod yields a rotational movement of said first engagement member. The first engagement member includes a grooved surface. A second engagement member is arranged at the barrel to engage with said grooved surface of the first engagement member, wherein the first engagement member is arranged to move relative to the second engagement member, such that feedback is given to a user as the plunger rod is moved relative to the barrel for driving said plunger. The first engagement member is arranged at said plunger rod with a predetermined play there between.
    Type: Grant
    Filed: December 21, 2016
    Date of Patent: July 5, 2022
    Assignee: Galderma Holdings SA
    Inventors: Anders Holmqvist, Max Blomqvist, Jonas Törnsten
  • Patent number: 11364343
    Abstract: An autoinjector including a plunger for engaging with the bung, a collar located around the plunger, an insertion spring biasing the collar relative to the rear of the device, and a delivery spring biasing the plunger relative to the collar. The device further includes a stop feature defining the limit of axial movement of the syringe body through the housing, and a collar release mechanism for releasing the collar from the rear of the device to commence insertion and a plunger release mechanism for releasing the plunger from the collar while substantially preventing rearward axial movement of the collar, following insertion, to commence delivery of the medicament. Following release of the plunger from the collar, the plunger is configured to move axially and rotationally relative to the collar, the direction of rotation being changed one or more times with axial movement of the plunger.
    Type: Grant
    Filed: March 15, 2018
    Date of Patent: June 21, 2022
    Assignee: Owen Mumford Limited
    Inventor: Andrew Hung
  • Patent number: 11364337
    Abstract: An automatic injector for delivering a pharmaceutical substance from a reservoir of a cartridge, the cartridge interconnected to a needle at its distal end and mechanically coupled to a plunger driver at its proximal end, the injector comprising a connecting feature on the cartridge a contact surface for contacting an injection site a frame connected to the contact surface, the frame having an interference element with a distal stop, the interference element sized to slidably link to the connecting feature and allow the cartridge to slide up to the distal stop, a snap element allowing the interference element to receive the connection feature, but inhibiting disconnection of the cartridge; the frame further comprising a driver mount, for fixedly containing a plunger driver, the driver for driving a plunger to empty the reservoir of the cartridge through the needle to inject fluid from the reservoir into the injection subject.
    Type: Grant
    Filed: September 16, 2019
    Date of Patent: June 21, 2022
    Assignee: West Pharma. Services IL, Ltd.
    Inventors: Oz Cabiri, Ran Hezkiahu