By Catheter Patents (Class 604/508)
  • Patent number: 11823480
    Abstract: A method for training an image classification model according to an embodiment includes training a feature extractor and a rotation angle classifier to predict a rotation angle of each of unlabeled first training images, training the image classification model to predict a label and rotation angle of each of labeled second training images, but predict a uniform label even though an actual rotation angle of each of the second training images is changed, generating a pseudo label based on a training image that satisfy a preset condition among unlabeled candidate images, and training the image classification model to predict a rotation angle of each of the third training images, and predict a label of each of the third training images based on the pseudo label, but predict a uniform label even though an actual rotation angle of each of the third training images is changed.
    Type: Grant
    Filed: June 2, 2021
    Date of Patent: November 21, 2023
    Assignee: SAMSUNG SDS CO., LTD.
    Inventors: Byoung Jip Kim, Jin Ho Choo, Yeong Dae Kwon, Jin Yeop Chang, Young June Gwon, Seung Jai Min
  • Patent number: 11793532
    Abstract: Systems, devices and methods for removing a blood clot (10) from a blood vessel (12). Various uses of suction pressure and positive pressure, proximal and/or distal to the blood clot (10) assist with clot dislodgement and removal. The pressure(s) may be constant and/or cycled/pulsed to assist with clot dislodgement and/or removal. Various further devices assist with separating the clot (10) from the vessel (12).
    Type: Grant
    Filed: July 19, 2021
    Date of Patent: October 24, 2023
    Assignee: Ischemicure Ltd.
    Inventor: Paul A. Spence
  • Patent number: 11696829
    Abstract: A method of repairing a defective heart valve is disclosed including directing an implant delivery catheter to form a first curve of the implant delivery catheter around chordae of the heart valve on a ventricular side of the heart valve, inserting the implant delivery catheter through the heart valve to an atrial side thereof, forming a second curve of the delivery catheter along an annulus of the heart valve on the atrial side, and ejecting an annuloplasty implant from the delivery catheter while retracting the delivery catheter such that the annuloplasty implant is arranged along the first and second curve on the ventricular and atrial side.
    Type: Grant
    Filed: March 5, 2020
    Date of Patent: July 11, 2023
    Assignee: Medtentia International Ltd Oy
    Inventors: Hans-Reinhard Zerkowski, Olli Keränen, Jani Virtanen
  • Patent number: 11541220
    Abstract: A needleless connector and methods for preventing microbial ingress in medical device connections are disclosed. Various examples provide a needleless connector including a male luer having a recessed distal tip surface containing a water-soluble antimicrobial composition. Further examples include a trap for retaining antimicrobial composition. As the needleless connector is inserted into a female connector, a tapered surface distal edge acts to push microorganisms, while the distal tip surface is configured to leave microorganisms undisturbed. After insertion of the needleless connector, microorganisms present on the female luer surface are biased to reside in the recess region. The recess, trap, and antimicrobial composition are configured to facilitate a long-lasting supply of antimicrobial solution within the fluid-filled recess, at the same time confining the antimicrobial solution inside the recess.
    Type: Grant
    Filed: June 20, 2019
    Date of Patent: January 3, 2023
    Assignee: ICU Medical, Inc.
    Inventors: Robert J. Ziebol, Matthew David Beilke
  • Patent number: 11541221
    Abstract: The disclosure provides a method for preventing infection and microbial ingress in medical device connections between tubing sets and medical devices. The tubing set includes a male connector with a distal tip and a recess at the distal tip configured to trap bacterial, and deliver and confine antimicrobial into solution within a cavity formed by the recess. The surface of the recess includes an antimicrobial composition. In certain implementations a male luer comprises a tapered sealing member further comprising a recess containing chlorhexidine acetate.
    Type: Grant
    Filed: June 21, 2019
    Date of Patent: January 3, 2023
    Assignee: ICU Medical, Inc.
    Inventors: Robert J. Ziebol, Matthew David Beilke
  • Patent number: 11534595
    Abstract: The present disclosure is directed to a device for delivering an antimicrobial composition into an infusion device. The disclosure provides a method for preventing infection and microbial ingress in medical device connections. The device includes a male connector with a distal tip and a recess at the distal tip. The surface of the recess includes an antimicrobial composition. In certain implementations a male luer comprises a tapered sealing member further comprising a recess containing chlorhexidine acetate.
    Type: Grant
    Filed: June 18, 2019
    Date of Patent: December 27, 2022
    Assignee: ICU Medical, Inc.
    Inventors: Robert J. Ziebol, Matthew David Beilke
  • Patent number: 11517732
    Abstract: Examples herein provide a syringe comprising a fluid reservoir and a male connector comprising a fluid flow channel in fluid communication with the fluid reservoir. The male connector including a male luer having a tapered sealing surface configured to mate with a female tapered surface of a female connector to form a substantially fluid-tight seal. The male luer has a distal tip with a recess defined by a recess surface that is distal to the tapered sealing surface. A water-soluble antimicrobial composition is disposed on the recess surface. The male luer is configured such that, when the male connector is mated with a female connector to form a substantially fluid-tight seal, a cavity is formed between the female tapered surface and the recess surface.
    Type: Grant
    Filed: September 3, 2019
    Date of Patent: December 6, 2022
    Assignee: ICU Medical, Inc.
    Inventors: Robert J. Ziebol, Matthew David Beilke
  • Patent number: 11400195
    Abstract: The disclosure provides a method for preventing infection and microbial ingress in medical device connections between peritoneal dialysis transfer sets and peritoneal dialysis catheters. A peritoneal dialysis transfer set includes a male connector with a distal tip and a recess at the distal tip configured to deliver and confine an antimicrobial composition into solution within a cavity formed by the recess. The surface of the recess includes an antimicrobial composition. In certain implementations the antimicrobial composition contains chlorhexidine acetate.
    Type: Grant
    Filed: August 28, 2019
    Date of Patent: August 2, 2022
    Assignee: ICU Medical, Inc.
    Inventors: Robert J. Ziebol, Matthew David Beilke
  • Patent number: 11259823
    Abstract: The present disclosure relates to electrically controllable surgical tools. In general, surgical devices are provided having an electrically controllable, fingered operating end for use in angiography, endovascular and/or neurological surgery. The finger(s) at the operating end can be made from ionic polymer metal composite (IPMC) material to facilitate control of the finger(s).
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: March 1, 2022
    Assignees: Maine Medical Center, Board of Trustees of the University of Maine System
    Inventors: Robert D. Ecker, Mohsen Shahinpoor
  • Patent number: 11179510
    Abstract: A method of assisting a heart of a patient using a dual lumen cannula includes inserting the dual lumen cannula into the patient, positioning a first infusion tube of the dual lumen cannula in an artery near the heart to pump blood thereto, positioning a second drainage tube of the dual lumen cannula in a chamber of the heart to drain blood therefrom. The dual lumen cannula has a plurality of infusion apertures extending through a sidewall of the first infusion tube at a distal end of the first infusion tube; and a plurality of drainage apertures extending through a sidewall of the second drainage tube at a distal end of the second drainage tube. The distal end of the first infusion tube has a tapered portion extending distally beyond a distal-most infusion aperture of the plurality of infusion apertures and to a terminal surface at a tip of the first infusion tube.
    Type: Grant
    Filed: May 6, 2019
    Date of Patent: November 23, 2021
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Patrick A. Kelly, Patrick E. Lutz, Robert G. Svitek, Jerry Stokes
  • Patent number: 11090070
    Abstract: A method of restoring perfusion to a blood vessel with an obstruction. The method includes delivering an expandable member into the blood vessel, said expandable member having a tubular mesh defined between a proximal end and a distal end; causing the expandable member to expand and compress the obstruction; and dislodging the obstruction to restore blood flow through the blood vessel.
    Type: Grant
    Filed: January 30, 2019
    Date of Patent: August 17, 2021
    Assignee: THE CLEVELAND CLINIC FOUNDATION
    Inventors: David Fiorella, Henry Woo
  • Patent number: 10973570
    Abstract: A catheter and catheter system can use energy tailored for remodeling and/or removal of target material proximate to a body lumen, often of stenotic material or tissue in the luminal wall of a blood vessel of a patient. An elongate flexible catheter body with a radially expendable structure may have a plurality of electrodes or other electrosurgical energy delivery surfaces to radically engage the luminal wall when the structure expands. Feedback using one or parameters of voltage, current, power, temperature, impedance magnitude, impedance phase angle, and frequency may be used to selectively control the delivery of energy.
    Type: Grant
    Filed: May 3, 2017
    Date of Patent: April 13, 2021
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Prabodh Mathur, Meital Mazor, Dolores Perez
  • Patent number: 10850020
    Abstract: In some aspects, a dialysis machine support assembly includes a platform configured to support a dialysis machine and a drive assembly configured to move the platform vertically.
    Type: Grant
    Filed: August 29, 2018
    Date of Patent: December 1, 2020
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: Gurpreet Singh, Sean Farrell, Michael David Young
  • Patent number: 10835869
    Abstract: The present disclosure provides instruments, modules and methods for improved detection of edited cells following nucleic acid-guided nuclease genome editing. The disclosure provides improved automated instruments that perform methods—including high throughput methods—for screening cells that have been subjected to editing and identifying cells that have been properly edited.
    Type: Grant
    Filed: July 14, 2020
    Date of Patent: November 17, 2020
    Assignee: Inscripta, Inc.
    Inventors: Phillip Belgrader, Don Masquelier, Matthew Estes, Bruce Chabansky, Andrew Garst, Richard Fox, Jorge Bernate
  • Patent number: 10806921
    Abstract: Devices, systems, and methods for specializing, monitoring, and/or evaluating therapeutic nasal neuromodulation are disclosed herein. A targeted neuromodulation system configured in accordance with embodiments of the present technology can include, for example, an evaluation/modulation assembly at a distal portion of a shaft and including a plurality of electrodes. The electrodes are configured to emit stimulating energy at frequencies for identifying and locating target neural structures and detect the resultant bioelectric properties of the tissue. The system can also include a console that maps locations of the target neural structures. The evaluation/modulation assembly can then apply therapeutic neuromodulation energy in a highly tailored neuromodulation pattern based on the mapped locations of the target neural structures. Accordingly, the system provides therapeutic neuromodulation to highly specific target structures while avoiding non-target structures to reduce collateral effects.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: October 20, 2020
    Assignee: National University of Ireland, Galway
    Inventors: David Townley, Brian Shields, Ivan Keogh, Peter Dockery, Ian Stephen O'Brien, Martin O'Halloran, Emily Elizabeth Porter, Marggie Jones
  • Patent number: 10799674
    Abstract: An innovative medical device that permits rapid, minimally invasive restoration of blood flow across a vascular blockage. A method employing said device, allowing for lysis or removal of said blockage. Said device creates a temporary bypass using longitudinal structure configured for insertion into the blood vessel and adapted to deliver a side hole to a target area. The side hole defines a distal first segment and a proximal second segment with a lumen to allow blood flow therethrough to the distal end hole. In an alternate embodiment, a slidable outer sheath can cover the side hole to permit reversal of blood flow from the distal end hole to a proximal end hole located outside a patient's body by means of an aspiration controller. Alternate embodiments include an optional anchoring balloon, a macerating stent or wires, perforations for fluid delivery, and a backflow valve.
    Type: Grant
    Filed: May 18, 2018
    Date of Patent: October 13, 2020
    Inventor: Daniel Ezra Walzman
  • Patent number: 10772599
    Abstract: Intravascular devices, systems, and methods are disclosed. In some instances, a method for treating a vessel of a patient includes collecting intravascular ultrasound imaging data of the placement of the stent using the intravascular ultrasound imaging device, estimating, using a processing device, a restenosis probability value based on the intravascular ultrasound imaging data of the placement of the stent and communicating the estimated restenosis probability value to a clinician. Associated devices and systems are also provided.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: September 15, 2020
    Assignee: PHILIPS IMAGE GUIDED THERAPY CORPORATION
    Inventor: Fergus Merritt
  • Patent number: 10729840
    Abstract: An assembly for an extracorporeal life support system with a suction line that features a venous cannula and a pressure line that features an arterial cannula furthermore includes a pump that is arranged between the suction line and the pressure line. This assembly has a discharge line with a discharge cannula, wherein the discharge cannula is longer than the arterial cannula, and wherein the discharge line is connected to the suction line or the pressure line.
    Type: Grant
    Filed: July 26, 2017
    Date of Patent: August 4, 2020
    Assignee: XENIOS AG
    Inventors: Ivo Simundic, Georg Matheis, Petr Ostadal
  • Patent number: 10709869
    Abstract: A hemodialysis split-tip catheter comprises an elongated portion, a proximal end and a distal end defining a longitudinal axis. The proximal end attaches to a hub with suture wings assembly, which in turn connected to extension tubings. The distal end has two distal tip segments splitted from each other. The first distal tip segment has a concave shape with respect to the longitudinal axis and the second distal tip segment has an approximately J-shape with respect to first distal tip segment. Diameter of concave shape of first distal tip segment is larger than diameter of J-shape of second distal tip segment to facilitate backward bend of second distal tip segment with respect to first distal tip segment after a catheter insertion inside a blood vessel to face a blood flow direction.
    Type: Grant
    Filed: June 18, 2018
    Date of Patent: July 14, 2020
    Inventor: Mohamed A Basiony
  • Patent number: 10688297
    Abstract: A system and method for deterring potential illicit use of extended-installations of catheters associated with patient care. A pair of legs are moveably associated together to collectively define a needle-defeating pathway between a pair of scissoring, offset, pinching surfaces disposed on mating surfaces of the legs when the legs are closed and clamped to an indwelling catheter. A single-use tamper evident locking system both maintains the legs closed and provides tamper evidence when opened, such as by disabling the locking system from further locking operation.
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: June 23, 2020
    Inventor: Hal Rucker
  • Patent number: 10603468
    Abstract: A method of coupling a catheter tunneler adapter to a catheter is provided. The method includes providing a catheter having a lumen divider at a proximal end thereof; forming a receiving notch in the lumen divider by removing a center portion thereof such that two divider side portions remain; providing a catheter tunneler adapter having a distal end including a radially inward step which defines a contact surface configured to be received in the proximal end of the catheter; positioning the distal end of the catheter tunneler adapter within the catheter until the radially inward step engages the receiving notch; and securing the catheter tunneler adapter to the catheter.
    Type: Grant
    Filed: May 8, 2018
    Date of Patent: March 31, 2020
    Assignee: MEDICAL COMPONENTS INC.
    Inventors: Charles Scandone, Jr., Mark S. Fisher
  • Patent number: 10595998
    Abstract: A method of repairing a defective heart valve is disclosed comprising directing an implant delivery catheter to form a first curve of the implant delivery catheter around chordae of the heart valve on a ventricular side of the heart valve, inserting the implant delivery catheter through the heart valve to an atrial side thereof, forming a second curve of the delivery catheter along an annulus of the heart valve on the atrial side, and ejecting an annuloplasty implant from the delivery catheter while retracting the delivery catheter such that the annuloplasty implant is arranged along the first and second curve on the ventricular and atrial side.
    Type: Grant
    Filed: June 19, 2017
    Date of Patent: March 24, 2020
    Assignee: Medtentia International Ltd Oy
    Inventors: Hans-Reinhard Zerkowski, Olli Keränen, Jani Virtanen
  • Patent number: 10569050
    Abstract: A wire assembly having a pre-shaped, flexible distal configuration deliverable through a vascular catheter, that assumes the pre-shaped distal configuration upon exiting the vascular catheter thereby permitting an operator to stabilize the position of a separate vascular guide catheter during a coronary interventional procedure.
    Type: Grant
    Filed: November 10, 2015
    Date of Patent: February 25, 2020
    Inventor: Christian M. Heesch
  • Patent number: 10543006
    Abstract: An infusion catheter system may deliver a therapeutic agent to a desired location in the body. The system may include an elongate catheter shaft having a proximal end region, a distal end region, a distal opening, and a lumen extending between the proximal end region and distal opening. The distal end region may include a coiled portion having a preformed coiled configuration including a plurality of helically wound rings. A plurality of apertures may be formed through a sidewall of the coiled portion. A guidewire may be configured to be slidably disposed within the lumen of the catheter shaft. The guidewire may include a proximal end region having a first cross-sectional dimension, an enlarged distal end region having a second cross sectional dimension greater than the first cross-sectional dimension, and an intermediate region disposed between the proximal end region and the distal end region.
    Type: Grant
    Filed: June 8, 2017
    Date of Patent: January 28, 2020
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Michael J. Bonnette, Jason T. Anderson, David B. Morris
  • Patent number: 10525250
    Abstract: The present disclosure is directed to an infusion device and method for preventing infection and microbial ingress in medical device connections. The infusion device comprising a male connector, the male connector comprising a male luer having an antimicrobial agent. In certain implementations the male luer comprises a tapered sealing member further comprising a recess containing chlorhexidine acetate.
    Type: Grant
    Filed: May 6, 2019
    Date of Patent: January 7, 2020
    Assignee: Pursuit Vascular, Inc.
    Inventors: Robert J. Ziebol, Matthew David Beilke
  • Patent number: 10434252
    Abstract: A flow rate sensor is provided in a wireless, leadless package. The flow rate sensor includes a MEMs sensor coupled to an ASIC and an antenna. The flow rate sensor is powered by radiation received from a control module adjacent the flow rate sensor. The flow rate sensor is placed within a fluid and monitors the flow rate of the fluid. The control module is not in the fluid and receives flow rate data from the flow rate sensor.
    Type: Grant
    Filed: December 29, 2015
    Date of Patent: October 8, 2019
    Assignee: STMicroelectronics, Inc.
    Inventors: Nicholas Trombly, Patrick Furlan
  • Patent number: 10426498
    Abstract: Devices, methods, and assemblies for perfusion therapy including cerebral perfusion therapy such as those for use in the treatment of acute ischemic stroke. The treatment includes delivery of blood to or about the vicinity of a thrombus site. 1. The device, assembly, and methods embodying features of the present invention NPS device employ suction/aspiration to assist in the removal of obstructions and/or to provide embolic protection from debris liberated during treatment.
    Type: Grant
    Filed: November 20, 2016
    Date of Patent: October 1, 2019
    Assignee: NEURONAL PROTECTION SYSTEM, LLC
    Inventors: Blaise Baxter, Thomas Devlin, Christian Devlin, Paul J. Fitzpatrick, Dirk V. Hoyns, Charles Rex Teeslink
  • Patent number: 10398892
    Abstract: A catheter assembly includes a cap and a spring-biased tethering member coupled thereto. The cap includes first and second portions, and a transition zone extending therebetween. A girth of the first portion is sized to fit within a distal-most opening of the catheter assembly; and a girth of the second portion tapers from a first size at the transition zone, which is too large to fit within the distal-most opening, to a smaller size at a distal end of the cap. The spring-biased tethering member holds the cap in open and closed positions, when the cap first portion extends within the distal-most opening, and when the cap is separated from the distal-most opening, respectively. At the closed position, the first portion is approximately concentric with the distal-most opening, and at the open position, an entirety of the cap is laterally offset from the distal-most opening.
    Type: Grant
    Filed: July 21, 2016
    Date of Patent: September 3, 2019
    Assignee: Medtronic, Inc.
    Inventors: Thomas A. Anderson, Andrea J. Asleson, Michael D. Eggen, McKenna Rose Redmond, Zhongping Yang
  • Patent number: 10238392
    Abstract: A device and system are described that are capable of isolating at least one targeted tissue and forming an anastomosis between two internal body structures though a completely endoscopic procedure. Further, the device and system described generally comprise two tubular members that are capable of moving in a telescopic fashion relative to one another. Additionally, a method is described for using the device and/or system to bypass the duodenum from digestion.
    Type: Grant
    Filed: February 9, 2015
    Date of Patent: March 26, 2019
    Assignee: CVDevices, LLC
    Inventors: Ghassan S. Kassab, Jose A. Navia, Sr.
  • Patent number: 10232140
    Abstract: A support device for preventing an occlusion of a catheter's root region including an extended, flexible member extending from an end of a catheter adapter. The flexible extension is tapered such that additional support is provided to the portions of the root region most susceptible to an occlusion. Additionally, the flexible extension provides shielding to the root region thereby preventing contamination of the same. Finally, the flexible extension provides a marking function whereby the technician may insert the catheter tube until such a point that the flexible extension contacts the patient thereby preventing over insertion of the catheter tube.
    Type: Grant
    Filed: December 18, 2007
    Date of Patent: March 19, 2019
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventor: Austin Jason McKinnon
  • Patent number: 10195030
    Abstract: Apparatus, comprising: (i) a catheter (64); (ii) an implant (100), comprising a flexible longitudinal member (102), and a linking member (104) that extends from a first linking site (106a) of the longitudinal member to a second linking site (106b) of the longitudinal member, the implant having: (a) a delivery state in which the longitudinal member is coaxial with the catheter, and at least a portion of the linking member is disposed alongside the longitudinal member, and (b) an implanted state in which a first distance between the first linking site and the second linking site, measured along the longitudinal member, is greater than a second distance between the first linking site and the second linking site, measured along the linking member; and (iii) a plurality of tissue anchors (46), slidable through the catheter and with respect to the longitudinal member. Other embodiments are also described.
    Type: Grant
    Filed: October 14, 2015
    Date of Patent: February 5, 2019
    Assignee: Valtech Cardio, Ltd.
    Inventors: Amir Gross, Tal Reich, Yaron Herman, Ehud Iflah, Haim Brauon, Meir Kutzik, Meni Iamberger
  • Patent number: 10123814
    Abstract: An infusion catheter has an elongate flexible shaft including a wall and a lumen extending between a proximal end and a distal end. The catheter also has a sealing member within the shaft lumen including a wall and a lumen. The catheter also has a slidable, retractable elongate central axis member extending through the shaft and sealing member lumens connected to an end cap. The catheter also has a plurality of eluting arms extending radially around the central axis member, including lumens fluidly connected to the shaft lumen and the distal end cap. A method for treating a thrombus is also disclosed.
    Type: Grant
    Filed: October 31, 2017
    Date of Patent: November 13, 2018
    Assignees: Temple University—Of The Commonwealth System of Higher Education, Pebble Hill Partners, LLC
    Inventors: Riyaz Bashir, Nick A. Green
  • Patent number: 10046174
    Abstract: In one example, a system electrically stimulates target cells of a living animal using an elongated structure, a modulation circuit and a light pathway such as provided by an optical fiber arrangement. The elongated structure is for insertion into a narrow passageway in the animal such that an end of the elongated structure is sufficiently near the target cells to deliver stimulation thereto. The modulation circuit is for modulating the target cells while the elongated structure is in the narrow passageway, where the modulation circuit is adapted to deliver viral vectors through the elongated structure for expressing light responsive proteins in the target cells. The light pathway is used for stimulating the target cells by delivering light to the light-responsive proteins in the target cells.
    Type: Grant
    Filed: March 20, 2013
    Date of Patent: August 14, 2018
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Karl Deisseroth, Alexander Aravanis, Feng Zhang, M. Bret Schneider, Jaimie M. Henderson
  • Patent number: 10039555
    Abstract: Systems and methods for treating disc herniation include surgical and endoscopic access and removal of disc tissue. The tissue removal devices that may be used include flexible elongate members, such as a cable, that may be inserted into a vertebral disc and rotated to pulverize the disc material and facilitate its removal.
    Type: Grant
    Filed: February 24, 2014
    Date of Patent: August 7, 2018
    Assignee: Spine View, Inc.
    Inventors: John T. To, Gary Daniel Zaretzka, Hiep Nguyen, Singfatt Chin, Robert May
  • Patent number: 9956377
    Abstract: A renal flow system injects a volume of fluid agent into a location within an abdominal aorta in a manner that flows bilaterally into each of two renal arteries via their respectively spaced ostia along the abdominal aorta wall. A local injection assembly includes two injection members, each having an injection port that couples to a source of fluid agent externally of the patient. The injection ports may be positioned with an outer region of blood flow along the abdominal aorta wall perfusing the two renal arteries. A flow isolation assembly may isolate flow of the injected agent within the outer region and into the renals. The injection members are delivered to the location in a first radially collapsed condition, and bifurcate across the aorta to inject into the spaced renal ostia. A delivery catheter for upstream interventions is used as a chassis to deliver a bilateral local renal injection assembly to the location within the abdominal aorta.
    Type: Grant
    Filed: September 23, 2013
    Date of Patent: May 1, 2018
    Inventors: Jeffrey M. Elkins, Aurelio Valencia, Samir R. Patel, Ricardo Aboytes, Harry B. Goodson, Craig A. Ball
  • Patent number: 9907946
    Abstract: Apparatus and methods of dispensing fluid intravenously to a subject, and of flushing a line of an intravenous fluid administration apparatus, are provided. The apparatus may include a chamber including a plurality of connector ports and be configured to operate in fluid communication with an upstream source via a first connector port and, during operation, pass therethrough to downstream tubing, under a first pressure condition, first fluid from the upstream source via a second connector port. A third connector port may be configured to connect to an end of tubing or a valve connector such that, during operation, the chamber is configured to, under a second, higher pressure condition, pass therethrough to the downstream tubing a second fluid from a second fluid source via the third and second connector ports, prevent first fluid flow into the downstream tubing, and prevent second fluid flow through the first connector port.
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: March 6, 2018
    Inventor: Joel S. Faden
  • Patent number: 9901728
    Abstract: The present invention relates to a catheter connector assembly having an insert for use during packaging, shipping, and handling of a catheter connector. The assembly includes a catheter connector having a body with a first half axially aligned with a second half. The first half is rotatable relative to the second half between an open position and a closed position. The first half defines a distal end of the body and the second half defines a proximal end of the body. A proximal end port is configured with the proximal end of the second half for mating communication with a fluid delivery device. The insert is configured with the body when the body is in the open position such that the insert maintains the catheter connector in the open position during packaging, shipping, and handling of the catheter connector.
    Type: Grant
    Filed: May 16, 2014
    Date of Patent: February 27, 2018
    Assignee: Avent, Inc.
    Inventor: Steve Saeed Khalaj
  • Patent number: 9801987
    Abstract: A bifurcated cannula for directing blood into the arterial system. The bifurcated cannula including an ingress channel and first and second egress channels. The first egress channel directs a first portion of the blood entering the bifurcated cannula into the arterial system in a first direction. The second egress channel directs a second portion of the blood entering the bifurcated cannula into the arterial system in a direction that opposes the first direction.
    Type: Grant
    Filed: January 14, 2015
    Date of Patent: October 31, 2017
    Assignee: CircuLite, Inc.
    Inventors: Robert C. Farnan, John P. Budris
  • Patent number: 9629981
    Abstract: A multipurpose catheter includes an un-tapered portion and a tapered portion, the latter being disposed distally of the former. The catheter has an arrangement of echo reflective features over at least a portion of the tapered portion. The echo reflective features may be echo reflective solely due to their shape, or may be made of radio opaque materials, and thus may provide a degree of echogenicity not only due to their material but also due to the reflectivity of their shape.
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: April 25, 2017
    Assignee: DOLCERA INFORMATION TECHNOLOGY SERVICES PRIVATE LIMITED
    Inventors: Praveen Thungana, Abhinandan Bhattacharya, Lakshmikant Goenka, Sumair Riyaz Hakaim, Anil Sharma
  • Patent number: 9605260
    Abstract: Provided herein are compositions and methods for the alteration of neuronal methylation by synthetic piRNAs or by alteration of piRNA function. Such alterations find use in the regulation and control of neural gene expression and concomitant neural functions. Further provided herein are systems and methods for the identification of target sites for regulation by piRNAs.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: March 28, 2017
    Assignee: IBIS BIOSCIENCES, INC.
    Inventors: David J. Ecker, Todd P. Michael, Lendell L. Cummins, Mark W. Eshoo, Stanley T. Motley, Danny M. Chou
  • Patent number: 9586031
    Abstract: Angioplasty and other dilatation devices are provided with scoring elements which incorporate a drug to be delivered to a body lumen, typically a blood vessel. The scoring elements have drugs and other active substances coated over a portion thereof or incorporated within internal structure of the element so that the drug is released into the luminal wall closely associated diseased regions of the body lumen as the scoring structure is radially expanded into the wall.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: March 7, 2017
    Assignee: AngioScore, Inc.
    Inventors: Eitan Konstantino, Michal Konstantino
  • Patent number: 9480524
    Abstract: An apparatus and method for treatment of a tubular anatomical structure is disclosed. The method includes using an electrical energy to destroy elongated cells on the tubular anatomical structure. The apparatus may include one or more electrodes for creating an electric field, and a cooling system for carrying heat away from the electrode. The elongated cells can include nerve cells on the tubular anatomical structure.
    Type: Grant
    Filed: January 6, 2015
    Date of Patent: November 1, 2016
    Assignee: Angiodynamics, Inc.
    Inventors: Victor Chorenky, Ali Jaafar
  • Patent number: 9433427
    Abstract: In one embodiment an aspiration system includes an elongate tubular member having a lumen; an aspiration catheter configured to be inserted through the lumen of the elongate tubular member, and including a tubular aspiration member having a proximal end, a distal end, and a lumen, and configured to at least partially extend out of the lumen of the elongate tubular member at the distal end of the elongate tubular member; an elongate support member coupled to the tubular aspiration member and extending between a proximal end of the aspiration catheter and the proximal end of the tubular aspiration member; and an annular sealing member coupled to the tubular aspiration member and configured to create a seal against an inner surface of the elongate tubular member, when a vacuum sufficient to cause aspiration is actively applied to the lumen of the elongate tubular member.
    Type: Grant
    Filed: April 6, 2015
    Date of Patent: September 6, 2016
    Assignee: INCUVATE, LLC
    Inventors: David M. Look, Bradley S. Culbert
  • Patent number: 9248221
    Abstract: In one embodiment, system for real time monitoring of catheter aspiration includes a housing having a first port adapted for connection to a vacuum source and a second port adapted for connection with an aspiration catheter, a pressure sensor in fluid communication with an interior of the housing, a measurement device coupled to the pressure sensor and configured for measuring deviations in fluid pressure, and a communication device coupled to the measurement device and configured to generate an alert signal when a deviation in fluid pressure measured by the measurement device exceeds a pre-set threshold. In another embodiment, the system for real time monitoring of catheter aspiration further includes a vacuum source for connection to the first port and an aspiration catheter having an aspiration lumen for connection to the second port.
    Type: Grant
    Filed: April 3, 2015
    Date of Patent: February 2, 2016
    Assignee: INCUVATE, LLC
    Inventors: David M. Look, Bradley S. Culbert
  • Patent number: 9242068
    Abstract: An infusion catheter includes a catheter body having a proximal end, a distal end, and two or more lumens extending therethrough. The infusion catheter also includes an infusion tube having a proximal end, a distal end, and one or more ports disposed therethrough. The first lumen of the catheter body is in fluid communication with the lumen of the infusion tube. A central member has a distal end connected to the distal end of the infusion tube, a proximal end, and a proximal portion slidably received in the second lumen of the catheter body. The infusion tube is disposed relative to the central member such that axial advancement of the central member relative to the catheter body radially collapses the infusion tube over the central member and axial retraction of the central member relative to the catheter body radially expands the infusion tube about the central member.
    Type: Grant
    Filed: July 17, 2009
    Date of Patent: January 26, 2016
    Assignee: Covidien LP
    Inventors: Michael Thai, Thomas Chien, Kelvin Ning, Robert Mcrae
  • Patent number: 9233200
    Abstract: A split-tip catheter for placement within the vasculature of a patient and for use in hemodialysis or other suitable procedures. In one embodiment, the split-tip catheter includes a catheter body defining a first lumen and a second lumen, and a split distal region extending from a distal end of the catheter body. The split distal region includes an arterial segment defined by an outer wall enclosing an arterial segment lumen, the arterial segment lumen in fluid communication with the catheter body first lumen, and a venous segment defined by an outer wall enclosing a venous segment lumen, the venous segment lumen in fluid communication with the catheter body second lumen, the venous segment outer wall extending from the catheter body distal end to a distal nose portion. The distal nose portion may taper distally from a first outer perimeter to a second outer perimeter smaller than the first outer perimeter.
    Type: Grant
    Filed: April 14, 2014
    Date of Patent: January 12, 2016
    Assignee: C.R. Bard, Inc.
    Inventors: Colin S. Gregersen, Ryan T. Moehle, Ryan C. Patterson
  • Patent number: 9227024
    Abstract: One or more intravenous catheter assemblies are monitored to ensure compliance with required hygienic procedures and/or to ensure only persons who have properly sanitized their hands are allowed to attend to such catheter assemblies. Detecting electrodes incorporated as part of such catheter assemblies facilitate determination as to whether potential contamination may have occurred. The hygienic status of a health care worker attending to the catheter assembly, as possibly evidenced by detected use of a sanitizer, may be used to determine whether the catheter assembly is being subjected to contamination.
    Type: Grant
    Filed: June 12, 2012
    Date of Patent: January 5, 2016
    Inventor: Richard Deutsch
  • Patent number: 9168163
    Abstract: A needle system for providing fluidic and/or instrument access to an internal body structure. Exemplary embodiments may include non-linear needles having anatomically appropriate lengths and curvatures. Some exemplary embodiments may include a pivotable base, which may assist in stabilizing the needle system with respect to a body structure and/or may be reconfigurable into a safety guard position. Exemplary needle systems may include expandable conduits providing fluidic and/or instrument pathways into internal body structures.
    Type: Grant
    Filed: February 18, 2010
    Date of Patent: October 27, 2015
    Assignee: P Tech, LLC
    Inventor: Peter M. Bonutti
  • Patent number: 9161830
    Abstract: Implant devices for filtering blood flowing through the ostium of an atrial appendage have component structures one or more of which are expandable. Devices with component structures in their unexpanded state have a compact size suitable for intra-cutaneous delivery to an atrial appendage situs. The expandable component structures are expanded in situ to deploy the devices. A device may have sufficiently short axial length so that most or almost all of the device length may fit within the ostium region.
    Type: Grant
    Filed: January 3, 2014
    Date of Patent: October 20, 2015
    Assignee: ATRITECH, INC.
    Inventors: Thomas E. Borillo, Dean A. Peterson, Gregg Sutton, Jeffrey Welch
  • Patent number: 9132000
    Abstract: Apparatus for permanent placement across an ostium of a left atrial appendage in a patient, which includes a filtering membrane configured to extend across the ostium of the left atrial appendage. The filtering membrane has a permeable structure which allows blood to flow through but substantially inhibits thrombus from passing therethrough. The apparatus also includes a support structure attached to the filtering membrane which retains the filtering membrane in position across the ostium of the left atrial appendage by permanently engaging a portion of the interior wall of the left atrial appendage. The support structure may be radially expandable from a first configuration to a second configuration which engages the ostium or the interior wall of the left atrial appendage. The filtering membrane may define an opening therethrough that is configured to expand from a first size which inhibits the passage of thrombus therethrough to a second size which allows an interventional device, e.g.
    Type: Grant
    Filed: June 19, 2013
    Date of Patent: September 15, 2015
    Assignee: ATRITECH INC.
    Inventors: Robert A. VanTassel, Robert G. Hauser, Robert Schwartz, David Holmes, Gregg S. Sutton, Thomas E. Borillo, Jeffrey Welch