Abstract: In one aspect, the dual bevel needle can include a hollow tube having a proximal end, a distal end, a first lateral side, and a second lateral side opposite the first lateral side; a first needle point at the distal end of the hollow tube; a second point at the distal end of the hollow tube; a first bevel on each of the first lateral side and the second lateral side, the first bevel comprising a first bevel angle relative to a longitudinal axis of the tube; and a second bevel on each of the first lateral side and the second lateral side, the second bevel having a second bevel angle relative to the longitudinal axis of the tube, wherein the first and second bevels each form a portion of an ellipse, the ellipse having an inner cutting edge and terminating in the first and second needle points at the distal end of the tube, the second bevel angle being shallower than the first bevel angle, the second bevel being located adjacent the proximal end of the first bevel, and the inner cutting edge converging to a narr

Abstract: Provided are phototherapeutic needle patches usable for phototherapy by using needle patches capable of injecting drugs or cosmetic substances to patients, and methods of manufacturing the same. A phototherapeutic needle patch may include a patch body attachable to skin of a patient, at least one microneedle protruding from the patch body, one end of the microneedle configured to deliver a drug through stratum corneum of the skin to inner tissues of the skin, and light grooves formed in a concave shape along a length direction of the microneedle in such a manner that therapeutic light radiated from a light source for phototherapy easily penetrates into the skin along the microneedle.

Abstract: The present invention provides a solution to increase the drug loading capacity and drug delivery precision of dissolving microneedles. These solutions include: (a) increasing the base of the microneedle cavities without substantially changing the microneedle's height and geometry, (b) use of drug suspension and sedimentation of drug by centrifugation, and (c) a specific centrifugation order for filling drug and matrix material. In the first preferred embodiment, a microneedle master mould comprising a plurality of pyramidal microneedles (5100), wherein each of the pyramidal microneedles further comprising a chamfered base (5200) which extends to and adjoins with its neighbouring chamfered bases is provided.

Abstract: A microprojection array comprising a substrate with a plurality of microprojections protruding from the substrate wherein the microprojections have a tapering hexagonal shape and comprise a tip and a base wherein the base has two substantially parallel sides with a slight draught angle of approximately 1 to 20 degrees up to a transition point at which point the angle increases to from about 20 degrees to about 70 degrees.

Abstract: A nozzle having at least one hole on an end portion having a plane with a size capable of holding a sheet-like water-soluble preparation. The nozzle also has concave-convex portions on a portion of the plane excluding the hole. An applicator for a sheet-like water-soluble preparation, which is composed of a liquid container and the nozzle.

Abstract: Systems, instruments, and methods for minimally invasive procedures including one or more of fractional resection, fractional lipectomy, fractional skin grafting, and/or fractional scar revision are described. Embodiments include instrumentation comprising a scalpet assembly coupled to a carrier, and the scalpet assembly includes a scalpet array. The scalpet array includes one or more scalpets configured for fractional resection, fractional lipectomy, fractional skin grafting, and/or fractional scar revision. The system includes a vacuum component coupled to the scalpet assembly and configured to evacuate tissue from the a site. The carrier is configured to control application of a rotational force and/or a vacuum force to the scalpet assembly.

Abstract: An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.

Abstract: A skin cleanser includes a surface, such as a silicone surface, with at least one textured portion for transmitting vibrational tapping to the skin. The skin cleanser includes at least one oscillating motor for generating the tapping motion to the skin. The textured portion in touch-points or a wave that transmit the tapping motion to skin in contact with the to portions. The touch-points may include thicker and thinner formations of the touch-points to provide firmer or softer vibrations to the skin. The touch-points are within about 0.5 to 2.5 mm in diameter. One configuration includes multiple oscillating motors configured to provide different vibration frequencies at around 50-300 Hertz and operable simultaneously.

Abstract: An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.

Abstract: A personal care appliance includes a housing having a first end and a second end located opposite and distal the first end, a treatment head member coupled to the first end of the housing, a sonic motor provided in the housing and being structured to oscillate the head member, and a drainage system comprising a pump provided in the housing, a first conduit fluidly coupled to the pump and the head member, and a second conduit fluidly coupled to the pump and the second end of the housing.

Abstract: A follicle container includes a receptacle to hold a hair follicle extracted from skin by a follicle extractor; a conduit, coupleable with the follicle extractor, to convey the extracted hair follicle toward the receptacle; and an injector to aerosolize and inject an irrigant into the conduit while the extracted hair follicle travels toward the receptacle. By injecting an irrigant into the conduit, the extracted follicle is less likely to be damaged on its journey to the receptacle. The irrigant lubricates the interior wall of the conduit and thus reduces friction between the extracted follicle and the wall as the follicle travels in the conduit. The irrigant also washes the interior of the conduit and keeps the extracted follicle moist and flexible. Flexibility allows the follicle to more easily suffer without damage bumps with the wall of the conduit and/or other extracted follicles as the follicle travels in the conduit.

Abstract: Exemplary embodiments of method and apparatus are provided for resurfacing of skin that includes formation of a plurality of small holes, e.g., having widths less than about 1 mm or 0.5 mm, using a mechanical apparatus, thus avoiding generation of thermal damage as occurs with conventional laser resurfacing procedures and devices. The holes formed can be well-tolerated by the skin, and can exhibit shorter healing times and less swelling than conventional resurfacing procedures. The apparatus includes one or more needles adapted to remove a small portion of tissue when inserted into and withdrawn from the skin. The fractional surface coverage of the holes can be between about 0.1 and 0.7, or between about 0.2 and 0.5. The exemplary method and apparatus can produce cosmetic effects such as increases in collagen content, epidermal thickness, and dermal/epidermal junction undulations in the skin.

Abstract: Exemplary embodiments of method and apparatus are provided for damaging and/or removing portions of subcutaneous fatty tissue while leaving the overlying dermal layer of the skin substantially undamaged. One or more hollow needles can be provided that include an arrangement within the lumen configured to retain or damage portions of fatty tissue that enter the lumen. Properties of the needle can be selected such that the needle can be inserted into skin and pass through the dermal layer, allowing fatty tissue to enter the distal portion of the lumen as it is advanced further, and then leaving the dermis undamaged when withdrawn. Such exemplary apparatus can include a plurality of such needles, a reciprocating arrangement to mechanically advance and withdraw the one or more needles, and/or a vibrating arrangement.

Abstract: A microprojection array comprising a substrate with a plurality of microprojections protruding from the substrate wherein the microprojections have a tapering hexagonal shape and comprise a tip and a base wherein the base has two substantially parallel sides with a slight draught angle of approximately 1 to 20 degrees up to a transition point at which point the angle increases to from about 20 degrees to about 70 degrees.

Abstract: Systems, instruments or devices, and methods or procedures are described in which a scalpet array is applied to a target site with the use of a pattern. The scalpet array comprises scalpets positioned on a device. Skin pixels are incised at the target site via application of a load through the scalpet array. A recipient site is prepared by positioning the pattern at the recipient site and applying the scalpet array to generate skin defects. The incised skin pixels are applied at the skin defects of the recipient site.

Abstract: A device for treating the skin comprises a handpiece assembly having a distal end and a proximal end, a cartridge comprising an interior cavity and a tip on the distal end of the handpiece assembly. The handpiece assembly includes a fluid delivery conduit and a waste conduit. In addition, the cartridge is coupled to the handpiece assembly with the interior cavity of the cartridge being in fluid communication with the fluid delivery conduit. Further, the tip is configured to contact the skin. The tip comprises a peripheral lip, a first opening in fluid communication with the fluid delivery conduit, a second opening in fluid communication with the waste conduit and an abrasive element. The first opening, the second opening and the abrasive element of the tip are generally positioned within the peripheral lip.

Abstract: An optical layer made from a light-permeable material includes a surface and an optical microstructure having a plurality of elevations. The elevations of the microstructure protrude from a reference plane, which is parallel to the surface. The elevations of the microstructure each have a flank section which adjoins the reference plane and forms a uniform angle with the reference plane. The uniform angle is in a range from about 10° to about 26° or in a range from about 13° to about 23° or in a range from about 15° to about 20°. The optical layer according to the invention makes it possible for a light fixture to achieve a high light output rate (LOR) at the same time to produce a preferred light distribution curve (LDC).

Abstract: An abrasive tip is used to exfoliate skin and tissue through abrasive materials integrated in the tip. The tip also delivers fluid to the skin and vacuums the fluid and abraded tissue during treatment. Treated skin will look younger and healthier in appearance. In an implementation, the tip is replaceable and disposable.

Abstract: A sensor is provided for sensing layer removal from a surface. A head has an abrasive portion for contacting the surface and a conducting portion inside the head. This device has a sensor design which provides self-generation of a sensor signal with no power supply to the device head. This simplifies the design of the sensor head, and means it can have a design which is easy to clean with no parts which are easily damaged. In one set of examples, the device is a skin treatment device.

Abstract: A method and apparatus for the treatment of, and reduction of inflammation caused by, carpal tunnel syndrome. The apparatus employing a massage head made of a thermally conductive material attached to a handle. The apparatus is used to apply pressure, via the massage head, at or in proximity to the wrist through reciprocal movement.

Abstract: Skin treatment systems, handpieces, suction wands, and methods of treatment are disclosed herein. A skin treatment system includes a treatment handpiece with removable tips, a console unit, and a suction assembly. The console unit can have a pressurization device configured to be fluidically coupled to the suction assembly. The suction assembly is configured to hold a subject's skin while the treatment handpiece moves along the epidermis. The tips can replaced any number of times to perform during a treatment session.

Abstract: In one aspect, the present disclosure relates to a device for obtaining biological tissue. In some embodiments, the device can include a first row of a plurality of hollow tubes; a second row of a plurality of hollow tubes, adjacent the first row of hollow tubes; a third row of a plurality of hollow tubes, adjacent the second row of hollow tubes, the first, second and third rows forming an array of hollow tubes; wherein each hollow tube can include at least one point at the distal end of the hollow tube, the plurality of rows forming a two dimensional array of hollow tubes; wherein an inner diameter of the at least one tube is less than about 1 mm, the distal end of each of the hollow tubes is configured to be inserted into a biological tissue donor site to remove a portion of tissue therefrom when each of the hollow tubes is withdrawn from the donor site.

Abstract: Systems, instruments, methods, and compositions are described involving removing a portion of the epidermis within a donor site on a subject, and harvesting dermal plugs within the donor site. An injectable filler is formed by mincing the dermal plugs. The injectable filler is configured for injecting into a recipient site on the subject.

Abstract: Systems, instruments, and methods for minimally invasive procedures including one or more of fractional resection, fractional lipectomy, fractional skin grafting, fractional scar revision, and/or fractional tattoo removal are described. Embodiments include instrumentation comprising a scalpet assembly coupled to a carrier, and the scalpet assembly includes a scalpet array. The scalpet array includes one or more scalpets configured for fractional resection, fractional lipectomy, fractional skin grafting, fractional scar revision, and/or fractional tattoo removal. The system includes a vacuum component coupled to the scalpet assembly and configured to evacuate tissue from the a site. The carrier is configured to control application of a rotational force and/or a vacuum force to the scalpet assembly.

Abstract: Exemplary embodiments of method and apparatus are provided for resurfacing of skin that includes formation of a plurality of small holes, e.g., having widths less than about 1 mm or 0.5 mm. For example, such small holes can be produced using a mechanical apparatus that includes one or more abrading elements provided at the end of one or more rotating shafts, thus avoiding generation of thermal damage as occurs with conventional laser resurfacing procedures and devices. The holes thus formed can be well-tolerated by the skin, and may exhibit shorter healing times and less swelling than conventional resurfacing procedures. The fractional surface coverage of the holes can be between about 0.1 and 0.7, or between about 0.2 and 0.5. The method and apparatus can produce cosmetic improvements in the skin appearance by eliciting a healing response.

Abstract: A hand-held power tool housing is disclosed. The housing includes a first housing part on the edge of which a first rebate is formed and a second housing part on the edge of which a second rebate is formed. The first rebate and the second rebate are formed in a complementary manner to one another such that the first housing part and the second housing part can be assembled in an assembly direction. A groove is formed on the edge of the first housing part and a spring is formed on the edge of the second housing part, forming an interlocking groove-spring connection in a transverse direction to the assembly direction.

Abstract: A surgical device comprising: (1) a handpiece having a distal end portion; (2) a tubular member extending from the distal end portion, the tubular member having a lumen therethrough, the lumen comprising: (a) a proximal lumen portion, (b) a distal lumen portion, (c) a first central lumen portion, and (d) a second central lumen portion, the second central portion being located between the proximal lumen portion and the first central lumen portion, wherein the distal lumen portion diverges as the distal lumen portion extends away from the first central lumen portion in a distal direction, and the second central lumen portion diverges as the second central lumen portion extends away from the first central lumen portion in a proximal direction and; wherein the tubular member has wall with a substantially uniform thickness about the first central lumen portion.

Abstract: The invention provides a non-invasive skin treatment device (200) comprising: a light source (10) constructed for emitting treatment light (15), an optical system (20) constructed for focusing the treatment light along an optical axis (OA) to a focus position (320) inside the skin tissue (300), and an indenter (30) comprising a skin contact surface (34) having an aperture (A1) at a distance from the optical system for allowing the treatment light to be focused through the aperture into the skin tissue.

Abstract: Devices and methods for dermatology and more particularly to fluid enhanced skin treatment system for skin rejuvenation that can use an abrasive probe for removing epidermal layers while contemporaneously providing for the infusion of therapeutic fluids into the skin.

Abstract: A hand-held epilation device for removal of unwanted hair by a user which includes a body portion, arm, slider mechanism, and a rotatable flexible member. The slider mechanism is held under tension. The rotatable flexible member is held under tension and rotates which coils and uncoils two portions of the rotatable flexible member to grasp and remove unwanted hairs. The slider mechanism moves along the arm to maintain a consistent angle between two portions of the rotatable flexible member allowing one portion of the rotatable flexible member to act as an aid to help the user target removal of unwanted hair and permitting more precise hair removal.

Abstract: The present invention relates to devices for dermatology and more particularly to fluid enhanced skin treatment system for skin rejuvenation that can optionally use an abrasive probe for removing epidermal layers while contemporaneously providing for the infusion of therapeutic fluids into the skin.

Abstract: An ophthalmic instrument includes a shaft comprising a lumen. The instrument also includes a first arm extending from the lumen, the first arm having a first distal portion having a first flat tip. The instrument also includes a second arm extending from the lumen, the second arm having a second distal portion having a second flat tip that is positioned such that the second flat tip contacts the first flat tip when the first arm is forced towards the second arm. The first arm and the second arm comprise at least in part, a first material that is substantially transparent to electromagnetic radiation having a wavelength within a range of about 700-1200 nanometers (nm) and is substantially opaque to electromagnetic radiation having a wavelength within a range of about 400-700 nm.

Abstract: Reduced-pressure treatment systems and methods are disclosed that employ debridement mechanisms to remove unwanted tissue. In one instance, a reduced-pressure treatment system for treating a tissue site on a patient includes a manifold member for distributing reduced pressure to the tissue site, a support member for disposing proximate the tissue site and the manifold, and a debridement mechanism coupled to the support member. The debridement mechanism is for debriding the tissue site. The system further includes a sealing drape for placing over the tissue site and manifold member. The sealing drape is operable to form a fluid seal over the tissue site and manifold member. The system also includes a reduced-pressure subsystem for delivering a reduced pressure to the sealing drape. The system may further include a chemical-debridement subsystem. Other systems, manifolds, and methods are disclosed.

Abstract: An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.

Abstract: An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.

Abstract: Automated systems and methods for removing hair from a body surface is provided. The methods and systems are semi- or fully automated. Some of the steps of the methods comprise determining a hair growth phase and selecting hair follicles for depilation based at least in part of the identified hair growth phase. The energy delivery device may be attached to the robotic arm and directed to align with the hair follicle to be depilated.

Abstract: A method is described for brightening tattoos or pigmented images formed below the epidermis of an individual. A skin treating device having a treatment tip with a crystalline abrasive material permanently bonded thereto is moved across the skin surface covering the tattoo. The procedure results in the bonded crystalline abrasive material removing a portion of the surface of the epidermis of the skin area over said tattoos or pigmented images, resulting in a brightening of colored or black line tattoos and a sharpening of the lines in the image. Simultaneously applying a vacuum to the skin surface during the procedure and the application of skin serum during or after the procedure enhances the results.

Abstract: A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece. The device and method cut the fibrous structures under the skin that cause cellulite at an angle substantially parallel to the surface of the skin and replace these structures with a non-cellulite forming structure by deploying a highly fibrous mesh through a single needle hole to create a highly fibrous layer directly or through wound healing processes. A tool is provided to aspirate excess fluid and tissue from the treatment area.

Abstract: A detachable vertical cutter for insertion into a cylinder or tube is formed as a single unitary structure. The single blade has a pair of tool attachment end portions and a cutting blade extending in a loop between the attachment ends. The cutting blade is inclined vertically relative to a longitudinal axis of a cylinder or tube into which the attachment ends can slide into. The cutting blade has a cutting edge, a portion of which when extended free of the cylinder or tube will extend a distance greater than the tube outside diameter. The cutting edge when pushed inwardly and pulled outwardly between adjacent vertebrae scrapes and cuts disc material. When retracted the cutting blade deflects into the cylinder or tube for insertion or extraction into or from the disc space.

Abstract: A system for abrading skin to remove outer portions thereof includes an apparatus having a skin abrading head with a head portion and a skin abrading brush. The outer head portion has a rim for placement in contact with the skin along with the bristles of the brush. Air flow is generated in the head to bring the skin into engagement with the rim and bristles and transport removed skin portions.

Abstract: A dermatome having a head, a neck, and a handle. The head of the dermatome may include a main housing at least partially defining a cavity and a removable member that may be configured to removably engage the main housing. The main housing may include one or more features configured to guide the removable member into alignment with the main housing and/or one or more features configured to engage the removable member. The removable member of the dermatome may be made from a different material than the main housing. The neck may include a first portion and a second portion, where the first portion is made from a different material than the second portion. The dermatome may be configured to connect to one or more of a fluid power source, a battery power source, and a wall power source.

Abstract: The present disclosure generally relates to methods and compositions for treating skin. In some embodiments, the method uses an exfoliation tool. In some embodiments, the method uses an exfoliation tool together with selected skin care agents or compositions.

Abstract: A system for cosmetologists, dermatologists, trichologists, salon professionals and the general public to produce a customized hair or skin care product using a diagnostic device for analyzing hair, scalp, and skin conditions. The diagnostic device communicates the diagnostic data to a self-contained processing apparatus, which has software that can formulate a recipe for the hair or skin care product and generate operating instructions for producing the product based on the recipe. The processing apparatus comprises a housing unit having a control center, a plurality of removable canisters capable of holding ingredients for producing the hair or skin care product, a dispensing system for dispensing the ingredients to a mixing bowl, a mixing device for mixing the ingredients, and preferably a heating element for heating the ingredients in the bowl, wherein the apparatus produces the hair or skin care product according to the operating instructions to provide individualized treatment.

Abstract: An abrasive skin treatment device including a handle portion, a head portion including an exfoliating element, and a unitary pivoting mechanism providing relative movement between the handle portion and the head portion along at least two planes.

Abstract: Skin graft harvesting systems and methods are disclosed that utilize sensors to automate the harvesting of skin grafts or assist a user in deciding when the skin graft is ready to be harvested. Such systems and methods can reduce the burden of visual observation and ensure greater reliability and consistency of the grafts. The invention is particularly useful with harvesters that rely upon suction and/or heating to raise a plurality of small or “micro” blisters simultaneously.

Abstract: The invention relates to an epilator (10) comprising an epilation head (18) having at least one rotatable disc-shaped member (20), a massaging member (34) arranged next to the epilation head, and a drive structure for driving the massaging member (34). According to the invention, the drive structure comprises a cylinder (26) for contacting a circumference of said at least one disc-shaped member (20) for the purpose of being rotated by said at least one disc-shaped member (20) about a rotational axis (30), wherein the cylinder (26) has a contact surface which is symmetrical about the rotational axis (30). The drive structure may further comprise an eccentric tappet (32) arranged for being rotated by the cylinder (26).

Abstract: A method of an extraction of follicular cells which is based on a principle of a hair extraction from a skin of mammals by the help of an extraction device, when during the extraction remains preserved also the root part of the hair surrounded by follicular cells, where the essence of the invention is that at least one hair from a sampling point of the skin is sucked in by the help of vacuum which is led form a body of the extraction device into an interspace of a two-cone collet fixed partly to the body and partly to an arbor where is subsequently by the interspace closing between its inner cone and an outer cone by the help of a counter pressure of the arbor this hair grasped and after it extracted from the skin.

Abstract: A method of cleaning a dermatome includes sealing an inlet fluid path and an outlet fluid path of a valve of the dermatome, the inlet fluid path configured to deliver a pressurized fluid to an interior of the dermatome to power the dermatome when open, and the outlet fluid path configured to expel an exhaust fluid from the interior of the dermatome when open. The method further includes washing the dermatome with the inlet and outlet fluid paths sealed.

Abstract: A microdermabrasion system upgrade kit includes a plurality of couplers from which a user may choose one or more couplers in order to connect the upgrade kit to a vacuum source of an existing microdermabrasion system. In an implementation, the upgrade kit includes a power socket that the user can plug the vacuum source into.

Abstract: An apparatus for treating skin has a console with a user input device and a handpiece assembly. The handpiece assembly is configured to treat skin. A fluid line provides fluid communication between the console and the handpiece assembly. A manifold system is coupled to the console and controlled by the user input device. The manifold system is configured to hold releasably a plurality of fluid sources and deliver fluid from at least one of the plurality of fluid sources to the handpiece assembly.