Abstract: A gas chromatography analysis method includes separating a component in sample gas by introducing the sample gas into a separation column (4) using carrier gas, and detecting a component in sample gas that has passed through the separation column (4) by introducing the sample gas into a detector (6). The detecting includes individually taking out hydrogen gas and oxygen gas generated by electrolysis of water, and controlling flow rates of taken-out hydrogen gas and oxygen gas and supplying the taken-out hydrogen gas and oxygen gas to the detector as detector gas.

Abstract: A system and method for performing field-portable GC/MS measurements for the rapid sampling and measurement of high temperature boiling semi-volatile organic compounds in environmental samples, wherein other column bundles have cold spots that may prevent high temperature boiling semi-volatile components from eluting the GC column, this new design may eliminate those cold spots on the GC column.

Abstract: A flow cell can comprise a high-pressure, fluidic, flow-through housing that encloses and auto-aligns a heavy-walled, internally reflective low-cost glass capillary for concentrating and amplifying laser-excited spectra. The containment housing that encloses the capillaries can optionally sustain operational pressures of at least 10,000 psi. The pressure housing can be fitted with transparent optical windows that can accommodate laser-safe injection and spectra collection. The flow-cell design can adaptably accommodate different optical sampling configurations such as transmissive (forward scattering), reflective (backward scattering), or multipass, combined scattering. The flow cell size is scalable (lengthwise) to accommodate different applications or installations such as benchtop (lab), permanent (industrial), and portable (field).

Abstract: A device for separating one or more molecules of interest in a liquid specimen including a monolithic body defining a fractionation column. The column includes an inlet opening at a proximal end of the fractionation column; an outlet opening at a distal, opposite end of the fractionation column; a solid phase chamber positioned between the inlet opening and the outlet opening; a specimen introduction area adjacent a proximal end of the solid phase chamber; an analyte exit area adjacent a distal end of the solid phase chamber; an inlet chamber adjacent the inlet opening that tapers into the specimen introduction area; and an outlet chamber that extends from the analyte exit area to the outlet opening. A metered amount of solid phase packed within the solid phase chamber between a first porous frit and a second porous frit of the solid phase chamber.

Abstract: The present invention provides a stationary phase for solid-phase microextraction (SPME) devices based on nickel and titanium alloy nuclei and a metal-organic framework (MOF) exterior, which may be used for chromatographic analysis in environmental, food, etc. applications. The method of preparation of the stationary phases consists of a number of steps which provide a covalent adhesion of the MOF to the nickel/titanium alloy. In these stationary phases, the metal-organic framework is the only component that comes into contact with the sample to be analysed. The interior of the stationary phase is executed in nitinol and endows the system with thermal and mechanical stability, this being the first time that it is used to support a metal-organic framework, and presenting extractive advantages in comparison with commercial SPME stationary phases.

Abstract: Liquid chromatography techniques are disclosed. Specifically, the liquid chromatography technique includes providing a liquid chromatography system having a coated metallic fluid-contacting element, and transporting a fluid to contact the coated metallic fluid-contacting element. Conditions for the transporting of the fluid are selected from the group consisting of the temperature of the fluid being greater than 150° C., pressure urging the fluid being greater than 60 MPa, the fluid having a protein-containing analyte incompatible with one or both of titanium and polyether ether ketone, the fluid having a chelating agent incompatible with the one or both of the titanium or the polyether ether ketone, and combinations thereof.

Abstract: A wavy micro gas chromatography column includes a silicon substrate and a bonded glass cover. A micro channel having a rectangular cross section is etched on the silicon substrate and coated with a stationary phase film. A projection figure of the micro channel on the silicon substrate includes multiple regular wavy curves. Each wavy curve is formed through alternately connecting first upper arcs with first lower arcs. Because the groove has a curving structure, the carrier gas velocity is decreased as the increase of the arc angle, resulting in an improvement of the flow uniformity at the zones between two adjacent bends but also an enlarging nonsymmetric distribution at the bends. Thus, an optimal curving structure can make the overall flow more even, and in turn achieve a better separation performance compared to the straight channel columns. Meanwhile, a wavy channel realizes a longer column length on a given area.

Abstract: A porous layer open tubular (PLOT) column includes capillary tubing; one or two particle traps disposed inside one or two end sections of the capillary tubing; and a stationary phase comprising a porous or non-porous material coated inside a main section of the capillary tubing. A method for preparing a porous layer open tubular (PLOT) column includes preparing one or two particle traps inside one or two end sections of a capillary tubing; and preparing a stationary phase comprising a layer of a porous material coated inside a main section of the capillary.

Abstract: A chromatography column is prepared with a stationary phase comprising a deuterated poly(ethyleneglycol), or other deuterated polymer. Formation of the stationary phase can be performed using exactly the same methodology as used when forming a stationary phase with the equivalent non-deuterated polymer. The deuterated poly(ethyleneglycol), or other deuterated polymer, preferably has increased thermal stability as compared to non-deuterated poly(ethyleneglycol), or equivalent non-deuterated polymer. This reduces bleeding of the stationary phase during gas chromatography and allows the use of greater operating temperatures.

Abstract: A collimator fixed to the cold jet nozzle of a modulator of a two-dimensional gas chromatograph to aid in the alignment of the cold jet nozzle and loop modulator tube.

Abstract: Methods and related apparatuses and mixtures are described for chromatographic analysis. The described system includes a pressurized source of a mobile phase and a flow path in fluid communication with the pressurized source such that the mobile phase flows through the flow path. The system also includes an injector in fluid communication with the flow path and downstream of the pressurized source, the injector being configured to inject a sample into the flow path. A first column located downstream of the injector, contains a stationary phase, and forms part of the flow path. A first detector is positioned to detect properties of fluid in the flow path at a location downstream of the injector and upstream from the first column. A second detector is positioned to detect properties of fluid in the flow path at a location downstream of the first column.

Abstract: The invention relates to a vaporization injector for a gas chromatograph, said injector comprising a structure (11) mounted in a detachable manner on the gas chromatograph body and including the sample introduction means, the vaporization chamber and pneumatic connections for feeding the carrier gas to the vaporization chamber and to the septum purge means, as well as pneumatic connections for evacuating the splitted sample and carrier gases.

Abstract: A housing of a column unit is tubular-shaped, and includes a first opening and a second opening, and an inner space separated from outside air by an insulating material. An air cooling section including a cooling device is arranged on a side of the first opening of the housing. At the time of cooling the inside of the inner space of the housing, air is caused, by a fan, to flow through the air cooling section and from the side of the first opening to a side of the second opening. A column section including a separation column and a heater is arranged inside the housing. A gap through which air flows from the first opening to the second opening is formed between the column section and an inner wall of the inner space of the housing.

Abstract: A non-seizing taper used for purged capillary tubing connections in gas chromatography that stops capillary tubing at a predictable position within the taper during installation and maintains space for gas to flow past the capillary tubing. The disclosed taper is an improved component of commonly used purged devices such as inlet liners and purged unions. The arresting aspect of the taper simplifies the process of capillary tubing installation while ensuring that the tubing will reproducibly be positioned in the taper. One or more features of the taper prevent tubing from seizing within the taper so that the devices can be reused and ensure that there is open space for a portion of gas to flow around and past the tubing. The angle of the taper, the dimensions of the taper, and the nature of the features within the taper can be adjusted to meet specific performance, usability and/or manufacturability requirements.

Abstract: The problem to be solved by the present invention is to provide a monolith adsorbent which can adsorb a target sample easily in a short time or regardless of whether the amount of the sample is small or large and extract the sample with a small amount of solvent, and easily secure the sample necessary for analysis, and a method and an apparatus for adsorption and retention using the same. The present invention is a monolith adsorbent formed by allowing a monolith structure body to contain an adsorbing material such as activated carbon or graphite, exposing the adsorbing material on the surface of the structure body and further surface-treating the surface of the monolith structure body with a hydrophobic or hydrophilic compound or a resin.

Abstract: A non-seizing taper used for purged capillary tubing connections in gas chromatography that stops capillary tubing at a predictable position within the taper during installation and maintains space for gas to flow past the capillary tubing. The disclosed taper is an improved component of commonly used purged devices such as inlet liners and purged unions. The arresting aspect of the taper simplifies the process of capillary tubing installation while ensuring that the tubing will reproducibly be positioned in the taper. One or more features of the taper prevent tubing from seizing within the taper so that the devices can be reused and ensure that there is open space for a portion of gas to flow around and past the tubing. The angle of the taper, the dimensions of the taper, and the nature of the features within the taper can be adjusted to meet specific performance, usability and/or manufacturability requirements.

Abstract: Methods and related systems are described for improving component separations in chromatography through novel techniques. The improvements in separation is due primarily to the provision of differential acceleration of the components being separated. Various systems and methods for providing differential acceleration are described including: increasing the cross section of the column towards the column outlet, changing the thickness or other composition of stationary phase within the column, and providing a temperature and/or mobile phase velocity gradient along the column.

Abstract: A plate-type capillary column has extensibility that enables a capillary to be extended as a whole to improve resolution of a chromatograph by stacking respective plate-type capillary columns. The capillary column is provided with a plate having first and second face plate parts that face each other; a capillary that is formed inside the plate; a first bottom-equipped hole connected to one end part of the capillary and formed to open in the first face plate part; and a second bottom-equipped hole connected to the other end part and formed to open in the second face plate part, wherein as viewed from a direction vertical to the first face plate part or the second face plate part, on a capillary column first virtual circle, passing through the second bottom-equipped hole, one or more through-holes penetrating through the first face plate part and the second face plate part are formed.

Abstract: There is provided a capillary column comprising a flat cross section and a desired theoretical plate number and having both high resolution and high sample load capacity. The capillary column 1 comprising a stationary phase on an inactivated inner surface, which is used in gas chromatography, comprises a narrow part 3 formed in a central part of a cross section of internal space and a bulge part 4 formed on each of both sides of the narrow part 3.

Abstract: A method for the production of a separation microcolumn made in silicon wafer (11), for a chromatographic or gas-chromatographic system, is described. According to the method, a micro-trench (14) is first made in the silicon wafer. The micro-trench extends in depth in the silicon wafer (11) and along the entire path of the microcolumn. Then, a perfectly circular micro-channel (20), tangent to the upper surface of the silicon wafer (11), is obtained by an in-depth isotropic etching with reactive ions in the micro-trench (14). The microcolumn is functionalized by applying a stationary phase (SP) to the inner wall and finally, another wafer or a layer (17) of silicon or silicon oxide or polymeric material, that acts as a cap or cover, is applied onto the silicon wafer, thus closing the micro-channel. According to a variation, the functionalization is carried out after the micro-channel closure.

Abstract: Certain embodiments described herein are directed to chromatography systems that include a microfluidic device. The microfluidic device can be fluidically coupled to a switching valve to provide for selective control of fluid flow in the chromatography system. In some examples, the microfluidic device may include a charging chamber, a bypass restrictor or other features that can provide for added control of the fluid flow in the system. Methods of using the devices and methods of calculating lengths and diameters to provide a desired flow rate are also described.

Abstract: A gas chromatography system comprising a sample introduction device, an oven coupled to the sample introduction device and a detector coupled to the oven is disclosed. In certain examples, the oven may be configured to receive a chromatography column in a space in the oven. In some examples, the oven may be constructed and arranged to provide a substantially constant temperature to the space during an analysis stage of the gas chromatography system.

Abstract: The disclosure describes a substrate with a fluid-handling assembly coupled to the substrate, the fluid-handling assembly including a plurality of fluid-handling components removably coupled to the substrate and removably coupled to each other. The plurality of fluid handling components includes a gas chromatograph having a fluid inlet and a fluid outlet, and a detector array having a fluid inlet and a fluid outlet, wherein the fluid inlet of the detector array is fluidly coupled to the fluid outlet of the gas chromatograph. A control circuit is communicatively coupled to at least one of the plurality of fluid-handling components, and a readout circuit communicatively coupled to the detector array and to the control circuit. Other embodiments are disclosed and claimed.

Abstract: A capillary column (10) includes a tube structure having inner walls (14) and a sol-gel substrate (16) coated on a portion of inner walls (14) to form a stationary phase coating (18) on inner walls (14). The sol solution used to prepare the sol-gel substrate (16) has at least one baseline stabilizing reagent and at least one surface deactivation reagent resulting in the sol-gel substrate (16) having at least one baseline stabilizing reagent residual and at least one surface deactivating reagent residual. A method of making the sol-gel solution is by mixing suitable sol-gel precursors to form the solution, stabilizing the solution by adding at least one baseline stabilization reagent, deactivating the solution by adding at least one surface deactivation reagent to the solution, and reacting the solution in the presence of at least one catalyst.

Abstract: A porous layer open tubular (PLOT) column includes capillary tubing; one or two particle traps disposed inside one or two end sections of the capillary tubing; and a stationary phase comprising a porous or non-porous material coated inside a main section of the capillary tubing. A method for preparing a porous layer open tubular (PLOT) column includes preparing one or two particle traps inside one or two end sections of a capillary tubing; and preparing a stationary phase comprising a layer of a porous material coated inside a main section of the capillary.

Abstract: A vial feed device is equipped with a feed arm, which is positioned between a vial tray and an oven and below either of them and having a feeding housing unit and a cooling housing unit, and a vial up-and-down moving mechanism for placing and removing vials in and from vial tray and oven. Feed arm is rotationally driven by a drive motor to move a feeding housing unit, a cooling housing unit and up-and-down moving mechanism toward vial tray or oven. High-temperature vials in oven are housed in cooling housing unit until cooling time T elapses. After cooling time T elapses, cooling housing unit is moved to a lower part of vial tray by feed arm, to be returned to vial tray by up-and-down moving mechanism.

Abstract: The present disclosure relates to a spirally wrapped chromatographic structure, a system incorporating such structure and a method of providing such structure. The structure may include an absorber layer having a first surface and a second surface, wherein one or a plurality of channels are defined in the first surface. The structure may also include a support layer having a first surface and a second surface, the first surface of the support layer disposed on the second surface of the absorber layer, wherein the absorber layer and the support layer comprise a spiral configuration such that at least a portion of the first surface of the absorber layer contacts at least a portion of the second surface of the support layer.

Abstract: The present invention provides germania-silica-based sol-gel monoliths that form the solid-phase material for extraction, isolation, preconcentration, and separation of analytes. In one embodiment, the germania-silica-based sol-gel monolith can be used to coat surfaces of the inner walls of extraction and chromatographic columns. In a preferred embodiment, the sol-gel germania-silica monolith of the present invention is formed from hydrolysis and polycondensation of precursors comprising tetraethoxygermane, tetramethoxysilane, and polyethylene glycol. Also provided are methods of preparing the germania-silica-based sol-gel monolith of the present invention.

Abstract: In a fast gas chromatograph (GC) method and device for obtaining fast gas chromatography analysis, a capillary gas chromatography column is inserted into a resistively heated metal tube located mostly outside a standard gas chromatograph oven, which may serve as a heated transfer line to a flexible column that enters the resistively heated metal tube from its injector and exits into its detector. The fast GC device enables less than one minute full range temperature programming and cooling back analysis cycle time. The fast GC according to one embodiment is combined with mass spectrometry with supersonic molecular beams for the provision of fast analysis cycle time together with highly informative mass spectral information for improved sample analysis and identification.

Abstract: A method comprising liquefying a gas to thereby obtain a liquefied gas; injecting a sample into a mobile phase containing a solvent and a supercritical fluid formed from the liquefied gas; passing this mobile phase through a column so that the mobile phase containing desired substance is divided into the solvent and the gas; and separating the desired substance from the solvent, wherein when the pressure of the gas divided from the mobile phase is higher than the pressure of the gas fed for formation of the liquefied gas from gas supply device, the gas divided from the mobile phase is liquefied. Further, there is provided a vapor liquid separator for use in the method.

Abstract: A flow through cartridge for solid phase extraction of an analyte from a liquid has a cartridge body bounding a passage for retaining a sorbent. The passage extends from a first end face to a second end face, opposite the first end face of the cartridge body. The cartridge body is composed of a core of a first material extending around the passage and sealing rings of a second material, extending around an axis of the passage at the first and second end faces. Surface portions of the sealing rings constituting surface portions of the first and second end faces. The first material is stronger and stiffer than the second material.

Abstract: Methods and systems for cooling gas chromatography ovens that comprise a housing having a fluid entry and a sleeve positioned within the housing to provide a fluid gap between the inner surface of the housing and the outer surface of the sleeve, where the sleeve is coupled to the fluid entry, and where a cooling fluid from the fluid entry traverses the inner layer of the sleeve and thereafter the outer layer of the sleeve via the fluid gap. In one embodiment, the housing includes at least one adjustable fluid exit, and the fluid gap is in fluid communications with the fluid exit(s). The fluid entry and the sleeve can be concentric, and the sleeve can include a heating element. A fan can be positioned to drive the cooling fluid from the fluid entry.

Abstract: Methods and related systems are described for improving component separations in chromatography through novel techniques. The improvements in separation is due primarily to the provision of differential acceleration of the components being separated. Various systems and methods for providing differential acceleration are described including: increasing the cross section of the column towards the column outlet, changing the thickness or other composition of stationary phase within the column, and providing a temperature and/or mobile phase velocity gradient along the column.

Abstract: The invention is directed to an oven for use in gas chromatography. In one embodiment, the oven is comprised of a housing that defines an interior chamber within which a substantial portion of a heating element and a radial fan blade are located. The interior chamber also defines a space within which a separation column is located when the oven is in use. The substantial portion of the heating element is located so as to receive air, when the oven is in operation, that is being moved by the radial fan blade in a direction that is substantially perpendicular to the axis of rotation of the blade. The space within which a separation column is located is also defined so as to receive air, when the oven is in operation, that is being moved by the radial fan blade in a direction that is substantially perpendicular to the axis of rotation of the blade.

Abstract: A gas chromatographic device comprises an inlet system and a chromatography column. The inlet system includes a liner having pressure reducing means contained therein for reducing pressure between an inlet of the pressure reducing means and an outlet of the pressure reducing means. When the devise is in use, the chromatography column is positioned in the liner of the inlet system downstream from the pressure reducing means, and the chromatography column is under vacuum at its outlet.

Abstract: A device for capillary chromatography comprising at least one first receiving space arranged in a circuit board and of a form such that the first receiving space is suitable for at least partially receiving a coiled part of a capillary separation column. Also a method for manufacturing such a device. Using such a device and method the greatest possible advantage can be gained from both miniaturized and integrated gas chromatographs (minimal dead volumes; integration options; small thermal masses and rapid temperature regulation; low cost price; small dimensions, weight and energy consumption; portable and flexible in use) and from the use of a usual capillary separation column (very good separation; high precision and reproducibility). The capillary separation column can herein be heated uniformly, rapidly and accurately.

Abstract: A gas chromatograph comprising two separating devices disposed one behind the other, and through which a material sample is conducted by a carrier gas. A pressure regulator regulates the pressure of the carrier gas introduced into the first separating device. A controllable switching device is arranged between the two separating devices. The switching device contains a main gas path lying between the two separating devices and two auxiliary gas paths, which are connected to the main gas path through connecting gas paths and are both fed with the carrier gas and contain flow resistors and a controllable valve for setting different pressure conditions. The auxiliary gas paths are supplied with the carrier gas through the same pressure regulator to reduce the design and adjustment effort in setting the pressure conditions, where fixed resistors are used for the flow resistors.

Abstract: Embodiments of the present disclosure provide for collection devices, methods of making collection devices, methods of collecting gases and aerosol particles, and the like.

Abstract: A multicapillary bundle for use in a gas chromatograph. Each of the capillaries in the bundle is formed using a coating solution containing a stationary phase and a solvent. The capillaries are coated with stationary phase by reducing pressure at a vacuum end of the capillary and creating a moving interface between the coating solution and a film of stationary phase deposited on each of the capillaries. The reducing pressure at the vacuum end of the capillary and the temperature of the capillary are controlled to maintain motion of the moving interface away from the vacuum end of the capillary. Maintained movement of the interface prevents recoating of the stationary phase. A heating wire and capillaries are embedded in a thermally conductive polymer to create a highly responsive method of heating the multicapillary column. An electronic control device controls the feedback temperature of the multicapillary column using the heating wire.

Abstract: A degas assembly including a low pressure fluid channel for carrying a wash fluid at a first pressure, a pressurized channel for carrying eluent including a gas at a second pressure higher than the first pressure, and a degas separator defining a fluid barrier between the low pressure fluid channel and pressurized fluid channel, the separator configured to retain liquid in the pressurized fluid channel and allow gas to flow through the separator to the low pressure fluid channel. The pressurized fluid channel may extend along an outer periphery of the low pressure fluid channel. The eluent may be received from an eluent generator at a pressure of at least about 3300 psi, and in various embodiments up to about 5000 psi. A liquid chromatography system and method are also disclosed.

Abstract: In the invention, a collection device includes a flow through micro scale plate arranged to collect analyte. The plate includes holes, and sorbent coating on contact surfaces of the plate. The holes pass analyte fluid flow, for example analyte vapor so that fluid flow for collection may be generally perpendicular to the sorbent plate. Preferred embodiment plates include an integrated heater trace. In preferred embodiments, a high substantially perpendicular flow is used for collection and concentration, and during desorption and delivery a low substantially parallel flow is used. The low flow is selected to meet constraints of a detector system.

Abstract: The invention relates to a device and to a method for determining the proportion of fuel in a combustion engine lubricating oil. The device according to the invention comprises a column (12) with at least 22000 theoretical plates and a steady state phase capable of separating the fuel, the oil, the internal standard contained in the oil and the solvent, in which the oil and the internal standard are diluted, and a heating module (120) capable of causing an increase in the temperature of the column (12) at a rate of at least 350° C./min. In the method according to the invention, the column (12) is subjected to determined cycles during which the pressure of the carrier gas and the temperature are varied.

Abstract: A gas chromatograph (GC) apparatus capable of detecting abnormality, in which a reference retention index is obtained from a result obtained by analyzing a given substance and a retention-index reference substance under adequate analysis conditions using a normal column, and stored in a storage section. Further, under a condition that the apparatus can perform normal analysis, the given substance is subjected to GC analysis to obtain a reference retention time, and the obtained reference retention time is stored in the storage section. A diagnosis processing section is operable to compare each of an actual retention time and an actual retention index with a respective one of the reference retention time and the reference retention index. If a deviation therebetween or abnormality is detected, the diagnosis processing section is operable to estimate a causal factor of the abnormality.

Abstract: Methods for depositing a stationary phase in a tube for chromatography, in particular, as a variable gradient column are disclosed. The methods include providing a tube having a first end and a second end, the tube containing a fluid composition comprising a stationary phase precursor and a solvent, connecting the first end of the tube to a flow device, removing the solvent from a meniscus of the fluid composition, the solvent exiting the tube at the second end, and operating the flow device while removing the solvent such that the amount of the stationary phase precursor deposited within the tube changes as the meniscus retreats within the tube to deposit a stationary phase having a thickness gradient along the length of the interior of the tube.

Abstract: An apparatus and method for rapid fractionation of hydrocarbon phases in a sample fluid stream are disclosed. Examples of the disclosed apparatus and method include an assembly of elements in fluid communication with one another including one or more valves and at least one sorbent chamber for removing certain classifications of hydrocarbons and detecting the remaining fractions using a detector. The respective ratios of hydrocarbons are determined by comparison with a non separated fluid stream.

Abstract: A flow control system, method and device for performing thermal desorption is provided. In one embodiment, the system includes a first flow path in which gas flows from a first carrier gas inlet, through a first vessel in a first direction at a first flow rate to adsorb analytes on an adsorbent of said first vessel; a second flow path in which gas flows from a second carrier gas inlet, through said first vessel in the first direction at a second flow rate to further adsorb the analytes on the adsorbent of said first vessel; a third flow path in which a carrier gas flows through said first vessel in a second direction to carry desorbed analytes out of said first vessel; and wherein the second flow rate of carrier gas through said first vessel is greater than the first flow rate of carrier gas through said first vessel.

Abstract: Methods for depositing a stationary phase in a tube for chromatography. The resulting column may be a variable gradient column or a standard open tubular column with a uniform thickness stationary phase. The methods include providing a tube comprising an electrically conductive interior surface and having a composition within the tube, the composition comprising a stationary phase precursor and at least one of an electrolyte and a reactant precursor, and electrochemically reacting the reactant precursor or the stationary phase precursor to form a stationary phase in the tube.

Abstract: The present invention is an improvement to two-dimensional comprehensive gas chromatography. The improvement is a one valve switching modulator connecting the two separation columns. The valve includes either a two position eight-port valve or a two position twelve-port valve, and two transfer lines.

Abstract: A chromatography column and method for use in a liquid chromatography process includes a telescoping chromatography and piston tubes, with the piston tube having a porous layer partially obstructing flow therethrough. A chromatography clamp is selectively movable between open and closed positions, and configured to extend substantially 360 degrees about the periphery of the chromatography tube when closed. The chromatography clamp is configured to releasably maintain the chromatography tube and piston tube in fluid communication with one another. In particular embodiments, the chromatography clamp includes a ledge extending at an oblique angle relative to the transverse direction, which is configured to cam the clamp towards the closed position upon application of greater than atmospheric pressure within the chromatography column.

Abstract: A gas chromatography system comprising a sample introduction device, an oven coupled to the sample introduction device and a detector coupled to the oven is disclosed. In certain examples, the oven may be configured to receive a chromatography column in a space in the oven. In some examples, the oven may be constructed and arranged to provide a substantially constant temperature to the space during an analysis stage of the gas chromatography system.