Patents Represented by Attorney, Agent or Law Firm Alan H. Thompson
  • Patent number: 6785432
    Abstract: Disclosed herein is a photonic silicon filter capable of binding and detecting biological and chemical target molecules in liquid or gas samples. A photonic waveguiding silicon filter with chemical and/or biological anchors covalently attached to the pore walls selectively bind target molecules. The system uses transmission curve engineering principles to allow measurements to be made in situ and in real time to detect the presence of various target molecules and determine the concentration of bound target.
    Type: Grant
    Filed: May 31, 2002
    Date of Patent: August 31, 2004
    Assignee: The Regents of the University of California
    Inventors: Sonia Letant, Anthony Van Buuren, Louis Terminello
  • Patent number: 6783943
    Abstract: Rolling circle amplification (RCA) has been useful for detecting point mutations in isolated nucleic acids, but its application in cytological preparations has been problematic. By pretreating cells with a combination of restriction enzymes and exonucleases, we demonstrate RCA in solution and in situ to detect gene copy number and single base mutations. It can also detect and quantify transcribed RNA in individual cells, making it a versatile tool for cell-based assays.
    Type: Grant
    Filed: December 18, 2001
    Date of Patent: August 31, 2004
    Assignee: The Regents of the University of California
    Inventors: Allen T. Christian, Melissa S. Pattee, Cristina M. Attix, James D. Tucker
  • Patent number: 6780320
    Abstract: A magnetohydrodynamic fluidic system includes a reagent source containing a reagent fluid and a sample source containing a sample fluid that includes a constituent. A reactor is operatively connected to the supply reagent source and the sample source. MHD pumps utilize a magnetohydrodynamic drive to move the reagent fluid and the sample fluid in a flow such that the reagent fluid and the sample fluid form an interface causing the constituent to be separated from the sample fluid.
    Type: Grant
    Filed: June 20, 2002
    Date of Patent: August 24, 2004
    Assignee: The Regents of the University of California
    Inventors: Abraham P. Lee, Mark G. Bachman
  • Patent number: 6779803
    Abstract: A hand-held ergonomic material-handling device capable of moving heavy objects, such as large waste containers and other large objects requiring mechanical assistance. The ergonomic material-handling device can be used with neutral postures of the back, shoulders, wrists and knees, thereby reducing potential injury to the user. The device involves two key features: 1) gives the user the ability to adjust the height of the handles of the device to ergonomically fit the needs of the user's back, wrists and shoulders; and 2) has a rounded handlebar shape, as well as the size and configuration of the handles which keep the user's wrists in a neutral posture during manipulation of the device.
    Type: Grant
    Filed: September 19, 2000
    Date of Patent: August 24, 2004
    Assignee: The Regents of the University of California
    Inventors: Lance E. Barsnick, David M. Zalk, Catherine M. Perry, Terry Biggs, Robert E. Tageson
  • Patent number: 6775053
    Abstract: A high-gain preamplifier based on optical parametric amplification. A first nonlinear crystal is operatively connected to a second nonlinear crystal. A first beam relay telescope is operatively connected to a second beam relay telescope, to the first nonlinear crystal, and to the second nonlinear crystal. A first harmonic beamsplitter is operatively connected to a second harmonic beamsplitter, to the first nonlinear crystal, to the second nonlinear crystal, to the first beam relay telescope, and to the second beam relay telescope.
    Type: Grant
    Filed: February 13, 2002
    Date of Patent: August 10, 2004
    Assignee: The Regents of the University of California
    Inventors: Igor Jovanovic, Randal A. Bonner
  • Patent number: 6774560
    Abstract: A method of processing a composite material to tailor white light emission of the resulting composite during excitation. The composite material is irradiated with a predetermined power and for a predetermined time period to reduce the size of a plurality of nanocrystals and the number of a plurality of traps in the composite material. By this irradiation process, blue light contribution from the nanocrystals to the white light emission is intensified and red and green light contributions from the traps are decreased.
    Type: Grant
    Filed: September 19, 2000
    Date of Patent: August 10, 2004
    Assignee: The Regents of the University of California
    Inventors: Christine A. Smith, Howard W. H. Lee
  • Patent number: 6764583
    Abstract: Impedance measurements between the electrodes in an electric field is utilized to detect the presence of pathogens trapped in the electric field. Since particles trapped in a field using the dielectiphoretic force changes the impedance between the electrodes by changing the dielectric material between the electrodes, the degree of particle trapping can be determined by measuring the impedance. This measurement is used to determine if sufficient pathogen have been collected to analyze further or potentially to identify the pathogen.
    Type: Grant
    Filed: December 13, 2000
    Date of Patent: July 20, 2004
    Assignee: The Regents of the University of California
    Inventor: Robin R. Miles
  • Patent number: 6764187
    Abstract: A universally oriented liquid mirror. A liquid and a penetrable unit are operatively connected to provide a mirror that can be universally oriented.
    Type: Grant
    Filed: December 19, 2001
    Date of Patent: July 20, 2004
    Assignee: The Regents of the University of California
    Inventors: Dmitri D. Ryutov, Arthur Toor
  • Patent number: 6763050
    Abstract: A thin, planar laser material is bonded to a light guide of an index-matched material forming a composite disk. Diode array or other pump light is introduced into the composite disk through the edges of the disk. Pump light trapped within the composite disk depletes as it multi-passes the laser medium before reaching an opposing edge of the disk. The resulting compound optical structure efficiently delivers concentrated pump light and to a laser medium of minimum thickness. The external face of the laser medium is used for cooling. A high performance cooler attached to the external face of the laser medium rejects heat. Laser beam extraction is parallel to the heat flux to minimize optical distortions.
    Type: Grant
    Filed: January 26, 2001
    Date of Patent: July 13, 2004
    Assignee: The Regents of the University of California
    Inventors: Luis E. Zapata, Raymond J. Beach, Eric C. Honea, Stephen A. Payne
  • Patent number: 6761811
    Abstract: A system utilizing multi-stage traps based on dielectrophoresis. Traps with electrodes arranged transverse to the flow and traps with electrodes arranged parallel to the flow with combinations of direct current and alternating voltage are used to trap, concentrate, separate, and/or purify target particles.
    Type: Grant
    Filed: March 27, 2001
    Date of Patent: July 13, 2004
    Assignee: The Regents of the University of California
    Inventor: Raymond P. Mariella, Jr.
  • Patent number: 6763339
    Abstract: The method and system described herein use a biologically-based signal processing system for noise removal for signal extraction. A wavelet transform may be used in conjunction with a neural network to imitate a biological system. The neural network may be trained using ideal data derived from physical principles or noiseless signals to determine to remove noise from the signal.
    Type: Grant
    Filed: June 25, 2001
    Date of Patent: July 13, 2004
    Assignee: The Regents of the University of California
    Inventors: Chi Yung Fu, Loren I. Petrich
  • Patent number: 6761809
    Abstract: An electrically regeneratable battery of electrochemical cells for capacitive deionization (including electrochemical purification) and regeneration of electrodes is operated at alternate polarities during consecutive cycles. In other words, after each regeneration step operated at a given polarity in a deionization-regeneration cycle, the polarity of the deionization step in the next cycle is maintained. In one embodiment, two end electrodes are arranged one at each end of the battery, adjacent to end plates. An insulator layer is interposed between each end plate and the adjacent end electrode. Each end electrode includes a single sheet of conductive material having a high specific surface area and sorption capacity, preferably a sheet formed of carbon aerogel composite. The battery further includes a plurality of generally identical double-sided intermediate electrodes that are equidistally separated from each other, between the two end electrodes.
    Type: Grant
    Filed: January 3, 2002
    Date of Patent: July 13, 2004
    Assignee: The Regents of the University of California
    Inventors: Tri D. Tran, David J. Lenz
  • Patent number: 6759141
    Abstract: The invention uses iridium and iridium compounds as a protective capping layer on multilayers having reflectivity in the deep ultra-violet to soft x-ray regime. The iridium compounds can be formed in one of two ways: by direct deposition of the iridium compound from a prepared target or by depositing a thin layer (e.g., 5-50 angstroms) of iridium directly onto an element. The deposition energy of the incoming iridium is sufficient to activate the formation of the desired iridium compound. The compounds of most interest are iridium silicide (IrSix) and iridium molybdenide (IrMox).
    Type: Grant
    Filed: April 30, 2002
    Date of Patent: July 6, 2004
    Assignee: The Regents of the University of California
    Inventor: Shon T. Prisbrey
  • Patent number: 6758146
    Abstract: A magnet configuration comprising a pair of Halbach arrays magnetically and structurally connected together are positioned with respect to each other so that a first component of their fields substantially cancels at a first plane between them, and a second component of their fields substantially adds at this first plane. A track is located between the pair of Halbach arrays and a propulsion mechanism is provided for moving the pair of Halbach arrays along the track. When the pair of Halbach arrays move along the track and the track is not located at the first plane, a current is induced in the windings and a restoring force is exerted on the pair of Halbach arrays.
    Type: Grant
    Filed: November 27, 2002
    Date of Patent: July 6, 2004
    Assignee: The Regents of the University of California
    Inventor: Richard F. Post
  • Patent number: 6760356
    Abstract: A diode pumped, high power (at least 20W), short pulse (up to 2 ps), chirped pulse amplified laser using Yb:YAG as the gain material is employed for material processing. Yb:YAG is used as the gain medium for both a regenerative amplifier and a high power 4-pass amplifier. A single common reflective grating optical device is used to both stretch pulses for amplification purposes and to recompress amplified pulses before being directed to a workpiece.
    Type: Grant
    Filed: April 8, 2002
    Date of Patent: July 6, 2004
    Assignee: The Regents of the University of California
    Inventors: Gaylen V. Erbert, Subrat Biswal, Joseph M. Bartolick, Brent C. Stuart, John K. Crane, Steve Telford, Michael D. Perry
  • Patent number: 6755083
    Abstract: A method for distinguishing multiple targets using time-reversal acoustics. Time-reversal acoustics uses an iterative process to determine the optimum signal for locating a strongly reflecting target in a cluttered environment. An acoustic array sends a signal into a medium, and then receives the returned/reflected signal. This returned/reflected signal is then time-reversed and sent back into the medium again, and again, until the signal being sent and received is no longer changing. At that point, the array has isolated the largest eigenvalue/eigenvector combination and has effectively determined the location of a single target in the medium (the one that is most strongly reflecting). After the largest eigenvalue/eigenvector combination has been determined, to determine the location of other targets, instead of sending back the same signals, the method sends back these time reversed signals, but half of them will also be reversed in sign.
    Type: Grant
    Filed: April 22, 2002
    Date of Patent: June 29, 2004
    Assignee: The Regents of the University of California
    Inventor: James G. Berryman
  • Patent number: 6756091
    Abstract: A lightweight flywheel containment composed of a combination of layers of various material which absorb the energy of a flywheel structural failure. The various layers of material act as a vacuum barrier, momentum spreader, energy absorber, and reaction plate. The flywheel containment structure has been experimentally demonstrated to contain carbon fiber fragments with a velocity of 1,000 m/s and has an aerial density of less than 6.5 g/square centimeters. The flywheel containment, may for example, be composed of an inner high toughness structural layer, and energy absorbing layer, and an outer support layer. Optionally, a layer of impedance matching material may be utilized intermediate the flywheel rotor and the inner high toughness layer.
    Type: Grant
    Filed: May 10, 2000
    Date of Patent: June 29, 2004
    Assignee: The Regents of the University of California
    Inventor: James R. Smith
  • Patent number: 6753036
    Abstract: Described herein is a method to fabricate porous thin-film electrodes for fuel cells and fuel cell stacks. Furthermore, the method can be used for all fuel cell electrolyte materials which utilize a continuous electrolyte layer. An electrode layer is deposited on a porous host structure by flowing gas (for example, Argon) from the bottomside of the host structure while simultaneously depositing a conductive material onto the topside of the host structure. By controlling the gas flow rate through the pores, along with the process conditions and deposition rate of the thin-film electrode material, a film of a pre-determined thickness can be formed. Once the porous electrode is formed, a continuous electrolyte thin-film is deposited, followed by a second porous electrode to complete the fuel cell structure.
    Type: Grant
    Filed: July 16, 2001
    Date of Patent: June 22, 2004
    Assignee: The Regents of the University of California
    Inventors: Alan F. Jankowski, Jeffrey D. Morse, Randy Barksdale
  • Patent number: 6750960
    Abstract: A system and method of efficiently obtaining distance measurements of a target by scanning the target. An optical beam is provided by a light source and modulated by a frequency source. The modulated optical beam is transmitted to an acousto-optical deflector capable of changing the angle of the optical beam in a predetermined manner to produce an output for scanning the target. In operation, reflected or diffused light from the target may be received by a detector and transmitted to a controller configured to calculate the distance to the target as well as the measurement uncertainty in calculating the distance to the target.
    Type: Grant
    Filed: March 17, 2003
    Date of Patent: June 15, 2004
    Assignee: The Regents of the University of California
    Inventor: Mark W. Bowers
  • Patent number: 6749826
    Abstract: Airborne or aqueous organic compound collection using carbon nanotubes. Exposure of carbon nanotube-coated disks to controlled atmospheres of chemical warefare (CW)-related compounds provide superior extraction and retention efficiencies compared to commercially available airborne organic compound collectors. For example, the carbon nanotube-coated collectors were four (4) times more efficient toward concentrating dimethylmethyl-phosphonate (DMMP), a CW surrogate, than Carboxen, the optimized carbonized polymer for CW-related vapor collections. In addition to DMMP, the carbon nanotube-coated material possesses high collection efficiencies for the CW-related compounds diisopropylaminoethanol (DIEA), and diisopropylmethylphosphonate (DIMP).
    Type: Grant
    Filed: June 5, 2002
    Date of Patent: June 15, 2004
    Assignee: The Regents of the University of California
    Inventors: Thomas M. Tillotson, Brian D. Andresen, Armando Alcaraz