Patents Represented by Law Firm Amster & Rothstein
  • Patent number: 8119340
    Abstract: Provided are isolated and purified preparations of a combination of a light chain antibody gene and a heavy chain antibody gene, where the light chain and heavy chain antibody genes are the same among more than one patient with B cell chronic lymphocytic leukemia (B-CLL). Vectors comprising those genes and cells comprising those vectors are also provided, as are isolated and purified antibodies encoded by the antibody genes. Anti-idiotype antibodies, peptides, and aptamers that bind to the antigen-binding region of an antibody encoded by the antibody genes are additionally provided, as are multimeric molecules comprising multiple binding sites that bind to the antigen-binding region of an antibody encoded by the antibody genes.
    Type: Grant
    Filed: October 8, 2004
    Date of Patent: February 21, 2012
    Assignee: The Feinstein Institute for Medical Research
    Inventors: Bradley T. Messmer, Nicholas Chiorazzi, Emilia Albesiano
  • Patent number: 8121302
    Abstract: A device and method for improving the performance of an electro-acoustic transducer. An acoustic test signal is generated through the electro-acoustic transducer. The acoustic test signal is measured at multiple points on an ambient surface around the electro-acoustic transducer to create measured acoustic data. Based on the measured acoustic data, an acoustic power frequency response of the electro-acoustic transducer is calculated. A correction impulse response for the electro-acoustic transducer is determined based on the acoustic power frequency response. A correction filter applies the correction impulse response to a sound signal input to generate a sound signal output for playback through the electro-acoustic transducer.
    Type: Grant
    Filed: December 14, 2005
    Date of Patent: February 21, 2012
    Assignee: Real Sound Lab, SIA
    Inventor: Raimonds Skuruls
  • Patent number: 8114982
    Abstract: Provided are DNAs comprising a polynucleotide that encodes at least a first modified miR-30 precursor and a second modified miR-30 precursor. Also provided are vectors comprising the the DNAs, where the vector can replicate in a host cell. Additionally, specific lentiviral vectors comprising the above-described DNA are provided, as are methods of inhibiting expression of a target gene in a eukaryotic cell.
    Type: Grant
    Filed: November 28, 2007
    Date of Patent: February 14, 2012
    Assignee: Albert Einstein College of Medicine of Yeshiva University
    Inventors: Liang Zhu, Daqian Sun
  • Patent number: 8115745
    Abstract: An electronic device including an interactive display having an interactive mode and a non-interactive mode. The interactive display includes an image display device that displays a user-interactive imaged keypad in at least a portion of the image display device when the interactive display is in the interactive mode and that displays other image data in the at least a portion of the image display device when the interactive display is in the non-interactive mode, and a substantially transparent physical keypad that provides tactile feedback to a user indicating location of one or more imaged keys within the imaged keypad in response to one or more actuators disposed below the image display device.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: February 14, 2012
    Assignee: Tactile Displays, LLC
    Inventor: R. O'Neal Gray
  • Patent number: 8108283
    Abstract: A method for formulating a synthetic currency including the steps of borrowing an amount of funds in at least one first currency at a first interest rate, converting a portion of the borrowed funds to at least one second currency, investing the portion of the borrowed funds in an investment that pays interest which covers at least a portion of cost of borrowing the borrowed funds in the first currency, and providing a third currency based on the remaining portion of the borrowed funds.
    Type: Grant
    Filed: March 7, 2007
    Date of Patent: January 31, 2012
    Assignee: Barclays Bank PLC
    Inventors: Edoardo Dimitri, Filippos Kasimatis, Andrew Kaufmann
  • Patent number: 8101063
    Abstract: A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.
    Type: Grant
    Filed: January 28, 2011
    Date of Patent: January 24, 2012
    Assignee: Panasonic Corporation
    Inventors: Shoji Miyazaki, Hiroyuki Tokunaga, Yoshinobu Tokuno
  • Patent number: 8102031
    Abstract: An integrated circuit including a substrate; a circuit pattern formed over the substrate; and one or more fences formed around edges of the circuit pattern, each of the one or more fences having a determined electrical resistance which is used to detect the addition of malicious circuitry. Each fence has a determined electrical resistance which is used to monitor the validity of the fence.
    Type: Grant
    Filed: April 18, 2008
    Date of Patent: January 24, 2012
    Assignee: Photronics, Inc.
    Inventors: Brian Dillon, Christopher J. Progler
  • Patent number: 8101191
    Abstract: Provided are mycobacteria comprising (a) a mutation that is not in a SecA2 gene that attenuates the virulence of the mycobacteria in a mammalian host, and (b) a mutation in a SecA2 gene that eliminates SecA2 activity. Also provided are mycobacteria that comprise a mutation in a SecA2 gene that eliminates SecA2 activity, where the mycobacteria are not Mycobacterium tuberculosis or Mycobacterium smegmatis. Additionally provided are methods of inducing an immune response in a mammal and methods of inducing an immune response to a pathogenic mycobacterium in a human using the above mycobacterial mutants.
    Type: Grant
    Filed: January 11, 2007
    Date of Patent: January 24, 2012
    Assignees: Albert Einstein College of Medicine of Yeshiva University, The University of North Carolina at Chapel Hill
    Inventors: William R. Jacobs, Jr., Steven A. Porcelli, Miriam Braunstein
  • Patent number: 8097147
    Abstract: A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.
    Type: Grant
    Filed: January 31, 2011
    Date of Patent: January 17, 2012
    Assignee: Panasonic Corporation
    Inventors: Shoji Miyazaki, Hiroyuki Tokunaga, Yoshinobu Tokuno
  • Patent number: 8093163
    Abstract: A hydroengorged spunmelt nonwoven formed of thermoplastic continuous fibers and a pattern of fusion bonds. The nonwoven has either a percentage bond area of less than 10 percent, or a percentage bond area of at least 10% wherein the pattern of fusion bonds is anisotropic.
    Type: Grant
    Filed: August 2, 2007
    Date of Patent: January 10, 2012
    Assignee: First Quality Nonwovens, Inc.
    Inventors: Mordechai Turi, Michael Kauschke
  • Patent number: 8083165
    Abstract: The invention relates to a method for manufacturing dispersed mineral products by grinding the mineral raw material, sizing the same in a flow classifier, sorting the same in dispersion in air, and eliminating the dispersion air. Also disclosed are devices and installations for carrying out said method.
    Type: Grant
    Filed: May 18, 2006
    Date of Patent: December 27, 2011
    Assignee: OMYA GmbH
    Inventors: Thomas Mangelberger, Bahman Tavakkoli
  • Patent number: 8084041
    Abstract: Methods of treating a mammal that is deficient in CD4+ and/or CD8+ lymphocytes are provided. The methods comprise inoculating the mammal with an attenuated mycobacterium in the M. tuberculosis complex. In these methods, the mycobacterium comprises two deletions, wherein a virulent mycobacterium in the M. tuberculosis complex having either deletion exhibits attenuated virulence. Use of these mycobacteria for the manufacture of a medicament for the treatment of mammals deficient in CD4+ and/or CD8+ lymphocytes is also provided.
    Type: Grant
    Filed: January 23, 2004
    Date of Patent: December 27, 2011
    Assignee: Albert Einstein College of Medicine of Yeshiva University
    Inventors: William R. Jacobs, Jr., Tsungda Hsu, Vasan Sambandamurthy, Sheldon Morris, Stoyan Bardarov, Svetoslav Bardarov, legal representative
  • Patent number: 8080632
    Abstract: Provided are peptides having melanocyte stimulating hormone activity. Also provided are vectors encoding these peptides and transgenic cells comprising the above vectors. Additionally, methods of reducing or preventing release of an inflammatory cytokine from mammalian cells are provided, as are methods for treating a mammal suffering from, or at risk for, a condition mediated by an inflammatory cytokine cascade. Further provided are methods of reducing levels of an inflammatory cytokine in a mammal, methods of treating an overweight mammal, methods of decreasing food intake in a mammal and methods of inhibiting innate immunity in the digestive system of a mammal.
    Type: Grant
    Filed: September 1, 2006
    Date of Patent: December 20, 2011
    Assignee: The Feinstein Institute for Medical Research
    Inventor: Jesse Roth
  • Patent number: 8080595
    Abstract: The invention consists of a process for preparation of self-binding pigmentary particles, dry or in aqueous suspension or dispersion, using in a particular stage of the process a reverse emulsion formed from a dispersion in an oily phase of water particles and of at least one polymer of acrylamide with an acrylic monomer.
    Type: Grant
    Filed: May 6, 2008
    Date of Patent: December 20, 2011
    Assignee: Omya Development AG
    Inventors: Patrick Gane, Philipp Hunziker, Joachim Schoelkopf
  • Patent number: 8076318
    Abstract: Provided are caged compounds comprising a ligand that specifically reacts with a receptor not naturally present in mammals. The cage is released from the ligand upon illumination of the compound with light. Also provided are cells transfected with a gene of interest and a gene encoding a receptor, the gene of interest operably linked to a genetic element capable of being induced by the receptor when bound to a ligand, and the receptor not naturally present in the species of the cell. The cells also comprise a caged ligand of the receptor. Additionally provided are methods of inducing a gene of interest in the above cells. Also provided are methods of repressing a gene of interest in a cell using caged ligands of receptors. Methods are additionally provided for inducing elimination of a target sequence in a cell of a species, using a caged ligand and a recombinase.
    Type: Grant
    Filed: October 22, 2003
    Date of Patent: December 13, 2011
    Assignee: Albert Einstein College of Medicine of Yeshiva University
    Inventors: David S. Lawrence, Richard G. Pestell, Christopher Albanese
  • Patent number: 8074909
    Abstract: The present invention is directed to a method for dry milling a material containing a carbonate ore. The method comprises the following steps: (a) dry milling the material in at least one milling unit: (i) in the presence of at least one polyalkylene glycol polymer having monomer units forming a backbone, where at least 90% of the monomer units forming the backbone of the polymer are constituted by ethylene oxide, propylene oxide or their mixtures, and where the polymer has a molecular weight of at least equal to 400 g/mole, (ii) such that the milling unit contains a quantity of water that is less than 10% in dry weight of the material in the milling unit; (b) optionally classifying the material from step a) with at least one classification unit; and (c) optionally repeating steps a) and/or b) with all or part of the material from step a) and/or step b).
    Type: Grant
    Filed: May 22, 2007
    Date of Patent: December 13, 2011
    Assignees: Omya Development AG, Coatex S.A.S.
    Inventors: Patrick A. C. Gane, Matthias Buri, René Vinzenz Blum, Jacques Mongoin
  • Patent number: D651936
    Type: Grant
    Filed: July 22, 2011
    Date of Patent: January 10, 2012
    Inventor: John Edward Faget Humphries
  • Patent number: D652341
    Type: Grant
    Filed: July 22, 2011
    Date of Patent: January 17, 2012
    Inventor: John Edward Faget Humphries
  • Patent number: D653041
    Type: Grant
    Filed: July 27, 2010
    Date of Patent: January 31, 2012
    Assignee: Town & Country Linen Corp.
    Inventors: Lou Henry, Petros Stambolis
  • Patent number: D654255
    Type: Grant
    Filed: April 26, 2011
    Date of Patent: February 21, 2012
    Inventor: Dan Amzallag