Abstract: A device for use in regulating the flow of a working fluid, such as a refrigerant, includes a body defining an axial opening, and a piston received within the axial opening. The piston is moveable in the body and has first and second ends. An actuator, which in one embodiment, is a stepper motor, is coupled to the first end of the piston for providing a force to the piston. An inlet and an outlet are coupled to the body such that the input, the output and the body define a passageway for the working fluid. An articulating seat assembly is coupled to the second end of the piston.

Abstract: A tumor associated protein has been discovered to exhibit immunoreactivity to human monoclonal antibody L92. A ten amino acid peptide segment of the protein and a fourteen amino acid peptide which contains the ten amino acid peptide has also been isolated and exhibits immunoreactivity to the same antibody. Using truncated fusion proteins, the minimum recognition site for antibody binding was determined to be four amino acids. Also disclosed are polypeptide compositions against human tumors that includes the polypeptides or protein of the present disclosure, as well as antibodies reactive with these polypeptides that may be employed directly for treatment or diagnosis. A certain embodiment of the present invention is also the DNA sequence encoding the ten amino acid peptide and the DNA encoding the fourteen amino acid peptide which also exhibits immunoreactivity to human monoclonal antibody L92 and cytotoxic T cells.

Abstract: This invention relates to flagella-less strains of Borrelia and to novel methods for use of the microorganisms as vaccines and in diagnostic assays. Although a preferred embodiment of the invention is directed to Borrelia burgdorferi, the present invention encompasses flagella-less strains of other microorganisms belonging to the genus Borrelia. Accordingly, with the aid of the disclosure, flagella-less mutants of other Borrelia species, e.g., B. coriacei, which causes epidemic bovine abortion, B. anserina, which causes avian spirochetosis, and B. recurrentis and other Borrelia species causative of relapsing fever, such as Borrelia hermsii, Borrelia turicatae, Borrelia duttoni, Borrelia persica, and Borrelia hispanica, can be prepared and used in accordance with the present invention and are within the scope of the invention.

Abstract: Scroll saws produce an accumulation of sawdust or other debris removed from a workpiece during operation of the saw. This debris can block the operator's view of the cutting path of the saw. An improved device and method for removing accumulated debris from the cutting path of a saw blade is disclosed. A bellows is described, comprising a bellows section having an accordion-like structure and a flexible stem having a passage through which air may pass. The bellows may be manufactured as a single piece using a blow molding process to achieve greater structural integrity. A scroll saw having a bellows for removing debris and a protective cover for use with the bellows is also described.

Abstract: Recombinant human immunodeficiency virus antigens capable of immunologically identifying the presence of early anti-HIV antibodies are stably expressed in a number of cell lines. These antigens have several clinically important applications as non-hazardous tools in the detection of human immunodeficiency virus exposure/infection, and in screening methods for HIV infection in idiopathic chronic lymphopenia (ICL). These techniques are improved over existing immunologically based and PCR based detection methods, as they provide for the detection of infection/exposure in samples determined to be negative by conventional forms of these types of assays that do not detect anti-HIV gp160 antibodies that react to conformational epitopes of HIV. The invention finds particular application in the detection of human immunodeficiency virus exposure/infection in infants.

Abstract: A method of heating a chemical solution used in a well bore having a tubing string is disclosed. The well bore will intersect a hydrocarbon reservoir. The method will include providing a diesel engine that produces heat as a result of its operation. The engine will in turn produce a gas exhaust, a water exhaust, and a hydraulic oil exhaust. The method would further include channeling the exhaust to a series of heat exchangers. The method may further include flowing a treating compound into the heat exchangers and heating the treating compound in the series of heat exchangers by heat transfer from the exhaust to the treating compound. The operator may then inject the treating compound into the well bore for treatment in accordance with the teachings of the present invention. One such method would be to inject utilizing a coiled tubing unit. The novel thermal fluid heating system is also disclosed.

Abstract: The retinoblastoma protein (Rb) is the product of the retinoblastoma gene and has been found to contain mutations in retinoblastoma tumor cells. Two nuclear proteins that bind to Rb, p48 and p46 have been isolated and the genes have been cloned. These proteins bind to Rb competitively with the SV40 T antigen. p48 is shown to suppress heat shock sensitive Ras mutations in yeast and is implicated as a modulator of the retinoblastoma suppressor function of Rb.

Abstract: A currency identification system has at least two laterally displaced scanheads, one or more laterally moveable scanheads, or at least two laterally displaced sensors of a linear scanhead, the scanheads or sensors being positioned so as to permit scanning along at least two segments on a first side of a bill. The scanheads or sensors are capable of detecting characteristic information from the bill along the segments and generating corresponding output signals representing variations in the detected characteristic information from which scanned patterns of characteristic information may be generated. At least one scanned pattern is generated from the output signals, the at least one scanned pattern representing analog variations in the characteristic information along a segment of the bill.

Abstract: A polymeric composition for producing foam in which the polymeric composition comprises high density polyethylene, alkenyl aromatic polymer and, optionally, a resiliency modifier resin. The high density polyethylene is in an amount of from about 45 to about 90 weight percent of the polymeric composition. The high density polyethylene has a z-average molecular weight, M.sub.z, greater than about 1,000,000. The alkenyl aromatic polymer is in the amount of from about 3 to about 45 weight percent of the polymeric composition. The resiliency modifier resin is in the amount of from 0 to about 40 weight percent of the polymeric composition. The foam is produced in the absence of a significant amount of a stability control agent.

Abstract: The present invention relates to the use of tumor suppressor genes in combination with a DNA damaging agent or factor for use in killing cells, and in particular cancerous cells. A tumor suppressor gene, p53, was delivered via a recombinant adenovirus-mediated gene transfer both in vitro and in vivo, in combination with a chemotherapeutic agent. Treated cells underwent apoptosis with specific DNA fragmentation. Direct injection of the p53-adenovirus construct into tumors subcutaneously, followed by intraperitoneal administration of a DNA damaging agent, cisplatin, induced massive apoptotic destruction of the tumors. The invention also provides for the clinical application of a regimen combining gene replacement using replication-deficient wild-type p53 adenovirus and DNA-damaging drugs for treatment of human cancer.

Abstract: Methods and structures for pad reconfiguration to allow intermediate testing during the manufacture of an integrated circuit are disclosed. The methods and structures disclosed are particularly useful in testing an embedded subcircuit, such as a memory array within an embedded chip product. A bond pad reconfiguration etch and other means for reconfiguring a bond pad are also disclosed.

Abstract: An acrylic fiber exhibiting improved brightness and proccessability is disclosed. The fiber includes a synergistic combination of a delustrant and an optical brightener and is specifically useful in the manufacture of "terry" knitted athletic socks.

Abstract: Disclosed are Coleopteran-toxic B. thuringiensis .delta.-endotoxins, nucleic acid sequences, and transgenic plants expressing these genes. Methods of making and using these genes and proteins are disclosed as well as methods for the recombinant expression, and transformation of suitable host cells.

Abstract: Disclosed are compositions and methods of use that comprise engineered IgA antibodies that, when administered to a host are secreted across the epithelium into the mucosal barriers of the body providing external passive immunotherapy against agents such as viral, bacterial and eukaryotic pathogens. Also disclosed are mini antibodies comprising the minimal transcytosis domains.

Abstract: A process of the conversion of a heavy hydrocarbon into a lighter hydrocarbon utilizing a soluble transition metal salt and synthesis gas which includes soot particles and other impurities is disclosed. The inclusion of solid particles, such as soot, carbon black, silica fines has been found to decrease the formation of sediment during the reaction process.

Abstract: The invention, in its various embodiments is a method and apparatus for uniformly orienting shafts which contain an operational feature on one end and which are blunt on the other end. In one aspect of the present invention, a machine feeds the shafts onto a surface containing one or more slots, where the slots are shaped to completely receive a shaft only when the shaft is in a preferred orientation. Shafts which are in the preferred orientation are oriented 180.degree. differently from shafts which are not in the preferred orientation. Shafts which are not in the preferred orientation will be dislodged from the slots and sent down a first exit chute. Shafts which are in the preferred orientation are sent down a second exit chute. The method comprises dispensing the shafts into slots on a surface where the slots are shaped to completely receive a shaft only when the shaft is in a preferred orientation, and selectively removing shafts which are not in the preferred orientation from the slots.

Abstract: Disclosed are nucleic acid segments comprising synthetically-modified genes encoding Coleopteran-toxic B. thuringiensis .delta.-endotoxins. Also disclosed are methods of using these genes for the recombinant expression of polypeptides, the preparation of vectors containing the genes, and methods for transforming suitable host cells.

Abstract: A video file server includes an integrated cached disk array storage subsystem and a plurality of stream server computers linking the cached disk storage system to the data network for the transfer of video data streams. The video file server further includes a controller server for applying an admission control policy to client requests and assigning stream servers to service the client requests. The stream servers include a real-time scheduler for scheduling isochronous tasks, and supports at least one industry standard network file access protocol and one file access protocol for continuous media file access. The cached disk storage subsystem is responsive to video prefetch commands, and the data specified for a prefetch command for a process are retained in an allocated portion of the cache memory from the time that the cached disk storage subsystem has responded to the prefetch command to the time that the cached disk storage subsystem responds to a fetch command specifying the data for the process.

Abstract: A second stage healing abutment for forming and preserving in the mucosa above a dental implant a transmucosal opening large enough to receive an artificial tooth that faithfully replicates a natural tooth being restored, and a companion transfer coping having identical transmucosal portions for forming in a laboratory model a faithful replica of the transmucosal opening made of a resilient gingiva replicating material in which to fabricate the artificial tooth, and methods of using the same.