Abstract: A pharmaceutical preparation comprising flutamide, useful in the treatment of prostatic carcinoma, is disclosed.

Abstract: Disclosed is a kit for preparing a lyophilized alpha interferon gel formulation suitable for topical administration.

Abstract: Antihistamines of the formula ##STR1## wherein ##STR2## is a 5 or 6 membered ring which is phenyl or heterocyclic; ##STR3## is a six membered ring which is 2,3, or 4 pyridyl or is phenyl or substituted phenyl, with the proviso that is ##STR4## is a nitrogen containing ring, ##STR5## must be phenyl; Z is an alkylene chain having 0 to 2 carbon atoms in the chain, said 2 carbon chain optionally having one double bond, said chain optionally having either a carbonyl oxygen, or a hydroxy group as a substituent; W is ##STR6## wherein p is 1 or 2 and n is 1 or 2, R.sup.1 is C.sub.1 to C.sub.6 alkyl, R.sup.2 is hydrogen or C.sub.1 to C.sub.6 alkyl, and the dotted line represents an optional double bond, R.sup.2 being absent if the double bond is present, and Y is substituted carboxylate or substituted sulfonyl. Said antihistamines have little or no sedative effects.

Abstract: There are disclosed certain alkali metal, alkaline earth metal, amine and amino acid salts of 3-(n-butyl)-4-hydroxy-1-phenyl-1,8-naphthyridine-2(1H)-one which, unlike the parent compound, are useful for orally treating chronic obstructive lung diseases such as asthma, bronchitis and the like.

Abstract: This invention relates to imidazo[1,2-a]pyridine derivatives which are useful in the treatment of peptic ulcer diseases.

Abstract: Sodium, Potassium, Phthalidyl and Pivalyloxymethyl (5R,6S,8R)-6-(1-hydroxyethyl)-2-(2-hydroxyethylthio)-penem-3-carboxylates exhibit potent, broad spectrum antibacterial activity, are orally effective and chemically stable.

Abstract: Disclosed is an improved process for the synthesis of 6-bromo-17,21-dihydroxy-3,11,20-trioxo-1,4,-pregnadienes 17,21-diesters. In particular, this invention relates to the conversion of 17,21-dihydroxy-3,11,20-trioxo-1,4-pregnadienes 17,21-diesters to 6-borom-17,21-dihyroxy-3,11,20-trioxo-1,4-pregnadienes-17-21-diesters via bromination under ionic conditions, e.g. bromine in acetic acid.

Abstract: Compounds of the formula ##STR1## and their pharmaceutically acceptable acid addition salts are disclosed. The compounds are useful as anthelmintics.

Abstract: There is disclosed the antibacterial 5R,6S,8R-6-(1-hydroxyethyl)-2-(2-glycylaminoethylthio)penem-3-carboxylic acid, its pharmaceutically acceptable salts and esters as well as compositions containing them and methods for their use.

Abstract: There is disclosed the antibacterial 5R,6S,8R-2-(1-methyl-2-imidazolylmethylthio)-6-(1-hydroxyethyl)penem-3-car boxylic acid, its pharmaceutically acceptable salts and esters as well as compositions containing them and methods for their use.

Abstract: Disclosed is a tamper-resistant reclosable package containing highly visible tamper indicators.

Abstract: A wiper for a cosmetic applicator in which the size of the wiper orifice is adjustable.

Abstract: Cosmetic compositions for imparting artificial tan to human skin and shielding the skin from ultra-violet rays comprising dihydroxy acetone, octyl dimethyl PABA, water, oil, and surfactant. The composition has pH after compounding between 2.9 and 5.

Abstract: There is disclosed certain cyclopropyl substituted polyenes useful for treating dermatoses such as acne, psoriasis and epithelial cancers.

Abstract: This invention relates to 2,3-dihydro-2-(imidazolylmethyl)benzo(b)thiophenes, to intermediates useful in their preparation, and to processes for preparing said intermediates. Also included in the invention are pharmaceutical compositions and the method of use of the compounds as antifungal agents.

Abstract: There are disclosed antibacterially effective compounds represented by the formula ##STR1## wherein R.sub.2 represents a substituted or unsubstituted single ring or double fused ring aryl or heterocyclyl radical bonded to the sulfur atom by a ring carbon, selected from the group consisting of phenyl, naphthyl, benzothiazolyl, oxazinyl, pyridyl, purinyl, imidazolyl, pyrryl, thiazolyl, thiadiazolyl, benzimidazolyl, triazinyl, furyl, thienyl, thiazinyl, triazolyl, tetrazolyl and pyrimidyl, wherein when substituted, said aryl or heterocyclic rings have one or more substituent which can be the same or different(a) are on a ring carbon or heteroatom, and are independently selected from the group consisting of lower alkyl, ##STR2## and loweralkylene ##STR3## wherein R.sub.4 and R.sub.5 are the same or different and are independently selected from the group consisting of hydrogen, halogen and lower alkyl or(b) are on a ring carbon atom only and are selected from the group consisting of .dbd.