Patents Represented by Attorney, Agent or Law Firm Bryan Cave
  • Patent number: 8257743
    Abstract: Disclosed herein are multifunctional nanoparticles, comprising: polymer nanoparticles formed by loading a drug into a polymer; a gold thin film deposited on a portion of the surface of the polymer nanoparticles; and an antibody to a substance expressed on the surface of a cell to which the drug is to be delivered, the antibody being conjugated to the gold thin film. Also disclosed is a method for preparing multifunctional nanoparticles, the method comprising the steps of: loading a drug into a polymer to prepare polymer nanoparticles; depositing a portion of the surface of the polymer nanoparticles with a gold thin film; conjugating to the gold thin film an antibody to a substance expressed on the surface of a cell to which the drug is to be delivered; and separating from the resulting nanoparticles those in which a portion of the surface of the polymer nanoparticles is deposited with the gold thin film and conjugated with the antibody.
    Type: Grant
    Filed: June 29, 2007
    Date of Patent: September 4, 2012
    Assignee: Industry-Academic Cooperation Foundation, Yonsei University
    Inventors: Kyung Hwa Yoo, Jeon Soo Shin, Seungjoo Haam, Hui Yul Park, Jaemoon Yang
  • Patent number: 8256818
    Abstract: An embodiment of a vehicle mounted table system comprises hardware adapted to attach to a cargo area of a vehicle by way of one or more coupling mechanisms. The embodiment has a slider assembly adapted to slide relative to the hardware whereby the slider assembly can be slid at least partially out of a tailgate of the vehicle while the hardware remains attached to the vehicle. Operatively coupled to the slider assembly is one or more platforms, the platforms folding out of the vehicle through a hinge-turntable assembly. The embodiment also includes a canopy assembly having a flexible covering and one or more associated canopy supports, the one or more canopy supports adapted for attachment to the table structure when the tailgating assembly is fully deployed.
    Type: Grant
    Filed: August 25, 2010
    Date of Patent: September 4, 2012
    Inventor: Ernest Peter Tovani
  • Patent number: 8261231
    Abstract: Systems and methods for developing, customizing, and deploying mobile device applications are provided through a mobile application development and deployment platform. Preferably, these systems and methods are implemented in an Internet based environment that allows non-technical users to build sophisticated, highly-customizable cross-platform mobile applications. The platform allows users to select, input, create, customize, and combine various content, design characteristics, and application components, such as modules, some of which utilize features and functionality associated with various mobile devices and mobile operating systems. In certain embodiments, the platform allows users to compile, and generate a configuration file for, the mobile application that can be distributed to end users for execution on various mobile devices and mobile operating systems.
    Type: Grant
    Filed: February 14, 2012
    Date of Patent: September 4, 2012
    Assignee: Media Direct, Inc.
    Inventors: Scott Hirsch, Arsen Pereymer, Sunny Rajpal
  • Patent number: 8253022
    Abstract: A suspension tray is provided that is adapted to hold a plurality of cables and/or wires that includes a device for electrically bonding and grounding the tray. The tray includes a series of spokes forming a wire mesh support on which the cables and/or wires are placed. The device (which serves to electrically bond and ground the tray) includes a plurality of conductive elements affixed to the wire mesh support. Each conductive element may include two side portions and a middle portion. The two side portions are preferably sealed with a paint composition and the middle portion includes a conductive surface that is capable of electrically bonding and grounding the tray.
    Type: Grant
    Filed: June 23, 2009
    Date of Patent: August 28, 2012
    Assignee: Cablofil, Inc.
    Inventors: Robert Crain, Dallas Kellerman
  • Patent number: 8251952
    Abstract: The present disclosure provides for an airless intravenous (IV) bag which contains a specialized device, referred to herein as the airless intravasculature infusion device (AIVID). The AIVID allows one to view the amount of fluid in the IV bag but substantially decreases or completely prohibits the risk of an inadvertent air infusion into a patient.
    Type: Grant
    Filed: January 9, 2009
    Date of Patent: August 28, 2012
    Inventor: Jeremy Scott Curry
  • Patent number: 8254970
    Abstract: Systems, methods, and media are provided for facilitating bidirectional communication between a wireless device, such as cellular device, and a paging operator's network operations center (NOC). Messages from the paging NOC are received over a paging network through paging circuitry included in the wireless device. Certain embodiments are directed to systems and methods for transmitting status messages or response messages pertaining to the received messages from the wireless device to the paging NOC through an alternate network, such as a cellular network or the Internet. Other embodiments are directed to systems and methods for displaying the received messages, and for determining and displaying user response actions, based on data included in the messages and/or stored on the wireless device. These systems and methods take advantage of the benefits provided by paging and wireless devices in order to maximize the reliability and minimize the delay associated with the messaging system.
    Type: Grant
    Filed: November 18, 2011
    Date of Patent: August 28, 2012
    Assignee: Critical Alert Systems, LLC
    Inventors: Stephen Oshinsky, Ed Meyercord, Ted McNaught
  • Patent number: 8254846
    Abstract: In some embodiments, a connectivity device is configured to provide electrical power to a first electrical device and facilitate communications between the first electrical device and at least one second electrical device. The connectivity device further is configured to couple to a cigarette lighter and an external electrical power source. The connectivity device can include: (a) a first removable cigarette lighter adapter having: (1) a first electrical output interface; and (2) a power interface configured to removably couple to the cigarette lighter; (b) a base module having: (1) at least one first interface; (2) a second interface configured to removably couple to the first electrical output interface of the first removable cigarette lighter adapter and configured to also couple to the external electrical power source; (3) a third interface configured to removably couple to the first electrical device; and (4) a first control configured to receive operational instructions for the first electrical device.
    Type: Grant
    Filed: August 20, 2009
    Date of Patent: August 28, 2012
    Assignee: Belkin International, Inc.
    Inventors: Oliver Duncan Seil, Kelly Ferdman, David Kleeman, Richard James Elgie, Vijendra Nalwad, Vannin Gale, Timothy Brewer
  • Patent number: 8242096
    Abstract: Ascorbic acid compositions in the form of a powder and/or granules contain as principle components L-ascorbic acid and/or a pharmaceutically acceptable salt thereof, and a high molecular (300 kDalton or higher) pectin. The compositions are compressible into tablets with improved mechanical strength and hardness.
    Type: Grant
    Filed: February 13, 2009
    Date of Patent: August 14, 2012
    Assignee: DSM IP Assets B.V.
    Inventors: Chyi-Cheng Chen, Bruno Leuenberger
  • Patent number: 8245132
    Abstract: Some embodiments disclose a computer-implemented system configured to create an advertisement.
    Type: Grant
    Filed: November 26, 2008
    Date of Patent: August 14, 2012
    Assignee: Saepio Technologies, Inc.
    Inventors: Ronald Harold Brown, Matthew Jason Angell
  • Patent number: 8242166
    Abstract: Taxanes having an ethyl ester or cyclopropyl ester substituent at C(10), a keto substituent at C(9), a hydroxy substituent at C(7), a thienyl substituent at C(3?) and a cyclobutyloxycarbamate or cyclopentyloxycarbamate substituent at C(3?), pharmaceutical compositions comprising such taxanes, methods of treatment and administration, and methods of preparation of medicaments comprising the taxanes.
    Type: Grant
    Filed: March 24, 2009
    Date of Patent: August 14, 2012
    Assignee: Florida State University Research Foundation, Inc.
    Inventors: Phong Vu, Robert A. Holton
  • Patent number: 8242101
    Abstract: A method of inducing high anti-leukemia activity responsive to the combination of hydroxamic acid analogue histone deacetylase inhibitors and PKC412 against human acute leukemia characterized as expressing phosphorylated (p)FLT3 kinase by a novel flow cytometry-based assay.
    Type: Grant
    Filed: April 22, 2010
    Date of Patent: August 14, 2012
    Assignee: University of South Florida
    Inventor: Kapil N. Bhalla
  • Patent number: 8242455
    Abstract: A radiation detector comprises a substrate of diamond material and at least one electrode formed at a surface of the substrate. The electrode comprises electrically conductive material deposited in a cavity in the surface of the substrate so that at least a portion of the material of the electrode is below the surface of the substrate. The cavity will typically be an elongate trench or channel in which electrically conductive material such as boron-doped diamond is deposited. In some embodiments, at least two electrodes are located adjacent to one another at the surface of the substrate. In other embodiments, the device has a plurality of electrodes, at least one of which is located at a first surface and at least one of which is located at an opposed second surface of the substrate.
    Type: Grant
    Filed: November 12, 2007
    Date of Patent: August 14, 2012
    Assignee: Diamond Detectors Limited
    Inventors: Andrew John Whitehead, Christopher John Wort, Kevin John Oliver
  • Patent number: 8239606
    Abstract: In some embodiments, a switching device is configured to couple a first computer to a first peripheral device and one or more second peripheral devices. The switching device includes: (a) a switch configured to couple to the one or more second peripheral devices; (b) a first hub including: (1) a first upstream port configured to couple to the first computer; (2) a first downstream port configured to couple to the first peripheral device; and (3) at least one second downstream port coupled to the switch. Other embodiments are also disclosed herein.
    Type: Grant
    Filed: August 13, 2010
    Date of Patent: August 7, 2012
    Assignee: Belkin International, Inc.
    Inventor: Daniel Wiler
  • Patent number: 8235208
    Abstract: A case (100) for an electrical device includes: (a) a first portion (110) with a bottom surface (111); (b) a second portion (121) adjacent to the first portion; (c) a third portion (122) adjacent to the second portion; (d) a fourth portion (123) adjacent to the third portion; and (e) a fifth portion (132) with an interior surface (235) and adjacent to the fourth portion. In this embodiment, at least one of the first portion or the third portion is configured to be removably coupled to the electrical device. Additionally, when the case placed in an open configuration, the first portion is capable of being located over the fifth portion with the bottom surface of the first portion adjacent to the interior surface of the fifth portion.
    Type: Grant
    Filed: May 18, 2010
    Date of Patent: August 7, 2012
    Assignee: Belkin International, Inc.
    Inventors: Saharut Sirichai, Xin Fu
  • Patent number: 8234980
    Abstract: An apparatus for transporting a rider between two points on a cable or rope, having a plurality of supports configured to suspend the cable or rope between two points of unequal elevation and a trolley for transporting the rider supported by a harness on the cable or rope, the trolley having a mounting plate configured with a connection point to receive the rider's harness, a pulley rotatably mounted to the mounting plate to support the plate on the cable or rope, and a friction shoe mounted on the plate forward of the pulley to contact the upper portion of the cable or rope, wherein the connection point is located beneath the cable or rope between the centers of the pulley and the friction shoe.
    Type: Grant
    Filed: March 25, 2009
    Date of Patent: August 7, 2012
    Assignee: Adventure Holdings LLC
    Inventors: Daniel Blair Boren, Brett J. Epstein, Joel C. Haas, Jason B. Hickman, Gary P. Prus, David J. W. Lovinger, James R. Wilson, Jr.
  • Patent number: 8236346
    Abstract: The present invention provides methods for reducing A? deposition, A? neurotoxicity and microgliosis in an animal or human afflicted with a cerebral amyloidogenic disease, such as Alzheimer's disease (AD), by administering therapeutically effective amounts of the (R)-enantiomer of the dihydropyridine compound nilvadipine, also known as (?)-nilvadipine, to the animal or human. Further provided are methods for reducing the risk of A? deposition, A? neurotoxicity and microgliosis in animals or humans suffering from traumatic brain injury by administering (?)-nilvadipine after the traumatic brain injury and continuing treatment for a prescribed period of time thereafter.
    Type: Grant
    Filed: October 3, 2008
    Date of Patent: August 7, 2012
    Assignee: Alzheimer's Institute of America, Inc
    Inventors: Michael J. Mullan, Daniel Paris, Robert A. Ivey, III
  • Patent number: 8234986
    Abstract: An apparatus for processing fly ash comprising a heated refractory-lined vessel having a series of spaced angled rows of swirl-inducing nozzles which cause cyclonic and/or turbulent air flow of the fly ash when introduced in the vessel, thus increasing the residence time of airborne particles. Also disclosed is a method of fly ash beneficiation using the apparatus.
    Type: Grant
    Filed: June 16, 2006
    Date of Patent: August 7, 2012
    Assignee: The Sefa Group, Inc.
    Inventors: Jimmy C. Knowles, Richard F. Storm
  • Patent number: 8236347
    Abstract: The present invention provides methods for reducing A? deposition, A? neurotoxicity and microgliosis in an animal or human afflicted with a cerebral amyloidogenic disease, such as Alzheimer's disease (AD), by administering therapeutically effective amounts of the (R)-enantiomer of the dihydropyridine compound nilvadipine, also known as (?)-nilvadipine, to the animal or human. Further provided are methods for reducing the risk of A? deposition, A? neurotoxicity and microgliosis in animals or humans suffering from traumatic brain injury by administering (?)-nilvadipine after the traumatic brain injury and continuing treatment for a prescribed period of time thereafter.
    Type: Grant
    Filed: February 1, 2010
    Date of Patent: August 7, 2012
    Assignee: Alzheimer's Institute of America, Inc.
    Inventors: Michael J. Mullan, Daniel Paris, Robert A. Ivey, III
  • Patent number: 8231912
    Abstract: The present invention is directed to anti-microbial cleanser compositions comprising linalool, hinokitiol and dipropylene glycol. The present invention further provides methods for using these compositions to maintain eyelid hygiene, to treat an ocular disorder or to clean a skin surface. The cleanser compositions of the present invention can be in the form of a foam, gel or liquid.
    Type: Grant
    Filed: April 30, 2010
    Date of Patent: July 31, 2012
    Assignee: Advanced Vision Research, Inc.
    Inventors: Jeffrey P. Gilbard, Elisabeth Gilbard, legal representative, Yanick Douyon, Robert B. Huson
  • Patent number: D666545
    Type: Grant
    Filed: January 5, 2012
    Date of Patent: September 4, 2012
    Inventor: Russell Aaron Kappius