Patents Represented by Law Firm Ciotti & Murashige, Irell & Manella
  • Patent number: 4813051
    Abstract: A semiconductor laser array device comprising an active waveguide extending from one light-emitting facet to the other light-emitting facet, wherein said active waveguide is composed of a single main portion extending in the oscillation direction from said one light-emitting facet and constituting a loss waveguide, and a plurality of parallel branching portions extending from the end of said main portion to said other light-emitting facet and constituting a real index waveguide.
    Type: Grant
    Filed: January 20, 1987
    Date of Patent: March 14, 1989
    Assignee: 501 Sharp Kabushiki Kaisha
    Inventors: Mototaka Taneya, Mitsuhiro Matsumoto, Hidenori Kawanishi, Sadayoshi Matsui
  • Patent number: 4811351
    Abstract: A semiconductor laser array device comprising a substrate; an index-waveguiding area positioned on said substrate; a Fourier-converting area, which is adjacent to said waveguiding area and in which laser lights emitted with synchronized phases from said waveguiding area undergo the Fourier-conversion, positioned on said substrate; and a reflecting mirror, which is adjacent to said Fourier-converting area and by which said converted laser lights with a 0.degree.-phase shift mode are selectively reflected so as to be incident upon said waveguiding areas.
    Type: Grant
    Filed: April 7, 1987
    Date of Patent: March 7, 1989
    Assignee: Sharp Kabushiki Kaisha
    Inventors: Sadayoshi Matsui, Mototaka Taneya, Mitsuhiro Matsumoto, Hidenori Kawanishi
  • Patent number: 4810691
    Abstract: Two proteins that are found is bone and that have in vivo chondrogenic/osteogenic activity in combination with a co-factor are described. Both proteins also were active in combination with EGF in the in vitro TGF-.beta. assay. Each has a molecular weight of approximately 26,000 daltons by SDS-PAGE. Each is reduced to a single polypeptide indicating that the proteins are probably homodimers. One has an N-terminal sequence identical to that of human placenta-derived TGF-.beta. whereas the other has an N-terminal sequence that is different from that of TGF-.beta. derived from human placenta. The two proteins may be purified to homogeneity using RP-HPLC or acetic acid-urea gel electrophoresis.
    Type: Grant
    Filed: December 10, 1987
    Date of Patent: March 7, 1989
    Assignee: Collagen Corporation
    Inventors: Saeid Seyedin, Thomas Thomas, Hanne Bentz, Larry Ellingsworth, Rosa Armstrong
  • Patent number: 4811350
    Abstract: A semiconductor laser apparatus and housing are designed so that laser light leaving the housing through a window glass in the housing satisfies the following equation (3): ##EQU1## wherein d is the distance between the window glass and the laser light-emitting facet of the semiconductor laser device, .lambda.o is the oscillation wavelength of laser light, and .DELTA..lambda. is the space between the adjacent longitudinal modes.
    Type: Grant
    Filed: August 4, 1987
    Date of Patent: March 7, 1989
    Assignee: Sharp Kabushiki Kaisha
    Inventors: Osamu Yamamoto, Shigeki Maei, Hiroshi Hayashi, Hidenori Kawanishi, Nobuyuki Miyauchi
  • Patent number: 4807886
    Abstract: A Gattling-gun-like amusement game provides for manual control of the rate of firing and dispensing of dislodged targets as prizes to the player. The gun fires balls at round targets supported on rotating carousels. Dislodged targets roll to the front of an enclosure for dispensing to the player. The balls are separated and fed by an Archimedes' spiral to a feed tube connected to the gun. A sensor is used with controls to limit the number of balls provided to a player. The balls are fed through two successive nip regions formed by pinch rollers. The first is manually controlled by a crank to vary the rate of firing. Balls delivered from the first nip region are fired at high speed by a fast rotating, fixed speed second pinch roller.
    Type: Grant
    Filed: September 11, 1987
    Date of Patent: February 28, 1989
    Assignee: Atari Games
    Inventors: Daniel N. Van Elderen, Gerald J. Lichac
  • Patent number: 4808168
    Abstract: A single-use Veress-type pneumoneedle that has a flanged handle and a fixed valve subassembly that permit the pneumoneedle to be gripped like a syringe when it is being inserted. The stylet body is either a solid rod or a hollow tube. Insufflating gas is carried into the abdominal cavity through the lumen of the needle when the stylet is a solid rod or through the stylet lumen when the stylet is a hollow tube.
    Type: Grant
    Filed: May 19, 1986
    Date of Patent: February 28, 1989
    Assignee: Endotherapeutics
    Inventor: Jessica A. Warring
  • Patent number: 4806454
    Abstract: A method for the formation of a diffraction grating on a substrate using a holographic technique and an etching technique, wherein the periodicity of the pattern of the diffraction grating can be changed at will by a change of the light-path length of one of the two light fluxes from a holographic exposing system.
    Type: Grant
    Filed: June 24, 1987
    Date of Patent: February 21, 1989
    Assignee: Sharp Kabushiki Kaisha
    Inventors: Toshihiko Yoshida, Haruhisa Takiguchi, Shinji Kaneiwa, Sadayoshi Matsui
  • Patent number: 4806503
    Abstract: A method for the replacement of semiconductor devices in a multi-chip module that is constructed by mounting semiconductor devices on a tape carrier used as an electrical wiring substrate, wherein when at least one of said semiconductor devices develops a flaw, it is cut away at the finger sections that connect said defective semiconductor device to the tape, and then a different and non-defective semiconductor device having finger sections longer than those of said defective semiconductor device that has been removed is connected to said tape in such a manner that the finger sections of said different and non-defective semiconductor device are joined and connected to the corresponding finger sections retained on said tape.
    Type: Grant
    Filed: October 23, 1986
    Date of Patent: February 21, 1989
    Assignee: Sharp Kabushiki Kaisha
    Inventors: Hirokazu Yoshida, Hiroshi Nakatani, Keiji Yamamura
  • Patent number: 4806523
    Abstract: Inflammation, acute and/or chronic, is treated with a CIF (TGF-.beta.). The CIF may be administered locally or symstemically, depending upon the indication, and does not require coadministraion of activator or cofactor for efficacy.
    Type: Grant
    Filed: March 6, 1986
    Date of Patent: February 21, 1989
    Assignee: Collagen Corporation
    Inventors: Hanne Bentz, Larry Ellingsworth, Rosa Armstrong
  • Patent number: 4807235
    Abstract: A semiconductor laser device comprising a multi-layered semiconductor crystal containing an active region for laser oscillation, wherein the extended portions of said active region which are adjacent to both sides of one facet having the width of a selected value of said device constitute light-absorbing regions by which light in a high-order transverse mode is absorbed to a greater extent than that in a fundamental transverse mode, thereby achieving laser oscillation in a stable fundamental transverse mode up to a high output power.
    Type: Grant
    Filed: September 9, 1986
    Date of Patent: February 21, 1989
    Assignee: 501 Sharp Kabushiki Kaisha
    Inventors: Takahiro Suyama, Kohsei Takahashi, Saburo Yamamoto, Toshiro Hayakawa, Masafumi Kondo
  • Patent number: 4804650
    Abstract: Compounds and compositions comprising synthetic analogs of Atrial Natriuretic Peptides are provided, together with methods for their production and use as natriuretics, diuretics and/or vasodilators, or as intermediates for or modulators of such useful compounds or of native Atrial Natriuretic Peptides.
    Type: Grant
    Filed: March 16, 1988
    Date of Patent: February 14, 1989
    Assignee: Biotechnology Research Associates, J.V.
    Inventors: John A. Lewicki, Robert M. Scarborough, Jr., Lorin K. Johnson
  • Patent number: 4805183
    Abstract: A distributed feedback semiconductor laser device with a resonator comprising a multi-layered optical waveguide that contains an optical guiding area with a periodic corrugation, the optical guiding area being composed of at least two regions, a first region I and a second region II, wherein both the periodicity of the corrugation and the depth of each concave portion of the corrugation of the first region I of the optical guiding area are the same as those of the second region II of the optical guiding area, and moreover the thickness of the first region I of the optical guiding area is the same as that of the second region II of the optical guiding area, so that the effective refractive index of the first region I in the resonator direction becomes the same as that of the second region II in the resonator direction and the Bragg wavelength is maintained at a fixed level in the the resonator direction; and there is a difference in their refractive index at the interface between the first and second regions o
    Type: Grant
    Filed: January 4, 1988
    Date of Patent: February 14, 1989
    Assignee: Sharp Kabushiki Kaisha
    Inventors: Hiroaki Kudo, Haruhisa Takiguchi, Shinji Kaneiwa, Toshihiko Yoshida
  • Patent number: 4803867
    Abstract: A fluid meter, such as a density meter or a Coriolis-type mass flow meter is disclosed in which the fluid tube is mounted to allow for expansion and contraction relative to a base to which opposite ends of the tube are mounted. In the preferred embodiments, a single, rectilinear flow tube measuring section is bounded at each end by a thermally insulating wall having a linear bearing which allows longitudinal axial movement while restraining transverse movement. Disposed distally of the linear bearing relative to the flow tube measuring section is means for accommodating the expansion and contraction of the measuring section. In one embodiment this is in the form of a laterally coiled tube portion. In a serial double-tube flow sensor, three serial rectilinear and parallel sections of the flow tube pass through linear bearings similar to that of the single tube, with arcuate sections joining adjacent rectilinear sections.
    Type: Grant
    Filed: April 28, 1987
    Date of Patent: February 14, 1989
    Inventor: Erik B. Dahlin
  • Patent number: 4803690
    Abstract: A semiconductor laser comprising a triple-layered structure composed of an active layer for laser oscillation and a pair of optical guiding layers sandwiching said active layer therebetween, wherein the refractive index of each of said optical guiding layers is smaller than that of said active layer, and the bandgap of each of said optical guiding layers is greater than that of said active layer, and moreover diffraction gratings with different pitches are positioned on the outer side of each of said optical guiding layers.
    Type: Grant
    Filed: March 13, 1986
    Date of Patent: February 7, 1989
    Assignee: Sharp Kabushiki Kaisha
    Inventors: Haruhisa Takiguchi, Shinji Kaneiwa, Toshihiko Yoshida, Sadayoshi Matsui
  • Patent number: 4803695
    Abstract: A semiconductor laser apparatus comprising a semiconductor laser device and a semiconductor device, both of which are fixed on a single mounting base with a spacing of several mm or less therebetween in such a manner that one of the side faces of said semiconductor device faces a laser-emitting facet of said semiconductor laser device in a parallel manner, the side face of said semiconductor device being a facet, at least a part of which is coated with a reflecting dielectric film functioning so as to have laser light from said semiconductor laser device return to said semiconductor laser device therefrom.
    Type: Grant
    Filed: June 13, 1986
    Date of Patent: February 7, 1989
    Assignee: Sharp Kabushiki Kaisha
    Inventors: Osamu Yamamoto, Hiroshi Hayashi, Saburo Yamamoto
  • Patent number: 4803075
    Abstract: Injectable aqueous suspensions of biomaterials, such as cross-linked collagen, that contain a biocompatible fluid lubricant, such as glycogen or maltose, are disclosed. The inclusion of the lubricant significantly improves the intrusion of the suspension into soft tissue.
    Type: Grant
    Filed: June 25, 1986
    Date of Patent: February 7, 1989
    Assignee: Collagen Corporation
    Inventors: Donald G. Wallace, Hertsel Reihanian, Bruce B. Pharriss, William G. Braun
  • Patent number: 4803169
    Abstract: Methods are disclosed for detecting, staging and monitoring breast cancer. The methods involve determining the amount of certain antigens, designated W1 and W9, in serum via quantitative immunoassays using anti-W1 or anti-W9 monoclonal antibodies. The amount detected is compared with amounts of the antigen found in normal sera, sera from breast cancer patients of predetermined stage, or other samples of the patient's own serum, depending upon the purpose of the assay.
    Type: Grant
    Filed: February 5, 1986
    Date of Patent: February 7, 1989
    Assignee: Cetus Corporation
    Inventors: Peter S. Linsley, Vincent W. Ochs, Diane Horn, Joseph P. Brown, David B. Ring, Arthur E. Frankel
  • Patent number: 4801531
    Abstract: The invention offers an early detection method for atherosclerosis using genetic analysis to detect a polymorphisms shown to be correlated with this disease which are proximal to the apolipoprotein AI (apoAI) and aplipoprotein CIII (apoCIII) gene complex. All individuals with a 300 bp deletion 4 kb upstream of the apoAI gene are destined to experience severe atherosclerotic symptomologies. Individuals with a polymorphism 5.4 kb 5' of the apoAI gene or a PvuII polymorphism in the first intron of the apoCIII gene also seem to be at greater risk. A haplotype with MspI and XmnI/7.2 polymorphisms in this general region seem to be protected. Additional polymorphic sites in the DNA sequence associated with the apoAI/CIII gene complex provide a means for genetically fingerprinting individuals, and for identifying persons at risk with respect to disorders relating to lipid metabolism and transport.
    Type: Grant
    Filed: September 30, 1985
    Date of Patent: January 31, 1989
    Assignee: Biotechnology Research Partners, Ltd.
    Inventor: Philippe M. Frossard
  • Patent number: 4801439
    Abstract: A process for preparing tractable preceramic precursors of Group IIIA metal/Group VA nonmetal compounds, such as BN, in which a first reactant containing a Group VA nonmetal to hydrogen bond, such as ammonia or an amine is reacted with a second reactant containing a Group IIIA metal to hydrogen bond, such as a metal hydride, in the presence of a metal catalyst that catalyzes dehydrocoupling of the bonds to form the precursor. Further reaction of the precursor in the presence of the catalyst forms oligomeric/polymeric forms of the precursor.
    Type: Grant
    Filed: September 15, 1986
    Date of Patent: January 31, 1989
    Assignee: SRI International
    Inventors: Yigal D. Blum, Richard M. Laine
  • Patent number: D299820
    Type: Grant
    Filed: January 16, 1986
    Date of Patent: February 14, 1989
    Inventor: Alex Viera