Patents Represented by Attorney, Agent or Law Firm Curtis D. Kinghorn
  • Patent number: 7069634
    Abstract: An intraparenchymal infusion catheter system for delivering drugs or other agents to selected sites in an organism, such as a human, includes a pump that may be implanted or disposed outside the organism. A catheter is coupled to the pump. The catheter comprises a flexible biocompatible tubular portion terminating in a free distal end. The distal end of the catheter bears a rounded tip, a portion of which is slidably disposed within the lumen of the tubular portion. The tip is porous for discharging an agent or drug to a selected site. The tip has a microporosity of less than or equal to 0.22 microns. The tubular portion is composed from a material that will expand from its nominal size when exposed to a stimulus such as heat or a solvent and return to its nominal size when the stimulus is withdrawn. By expanding the tubular portion, a physician can select the amount of the tip that is exposed to the organism, thereby customizing the catheter to the structural size of the selected site within the body.
    Type: Grant
    Filed: February 24, 2000
    Date of Patent: July 4, 2006
    Assignee: Medtronic, Inc.
    Inventor: Dennis D. Elsberry
  • Patent number: 6719739
    Abstract: An implantable pump having a bulkhead, a reservoir structure attached to the bulkhead and upper and lower cases attached to the bulkhead by a single outer seal as well as a method of making such a pump is disclosed. The reservoir structure forms a reservoir that contains fluid drug or other medicaments. The upper and lower cases are attached to the bulkhead by first connecting either the upper or lower case directly to the bulkhead. Then, the lower or upper case not attached to the bulkhead is attached to the upper or lower case that had been previously attached to the bulkhead.
    Type: Grant
    Filed: August 27, 2001
    Date of Patent: April 13, 2004
    Assignee: Medtronic, Inc.
    Inventors: Maurice T. Y. Verbeek, Frans Philippens
  • Patent number: 6675046
    Abstract: A system and method is described for preferentially stimulating dorsal column fibers while avoiding stimulation of dorsal root fibers. The invention applies hyperpolarizing pre-pulses and depolarizing pre-pulses to neural tissue, such as spinal cord tissue, through a lead placed over the spinal cord having the electrodes arranged on a line approximately transverse to the axis of the spine. To increase the threshold needed to stimulate dorsal root fibers, the anodal pulse given by each lateral contact of the electrodes has to be preceded by a depolarizing pre-pulse and simultaneously, the central electrode contact gives a hyperpolarizing pre-pulse, thereby reducing the stimulation threshold for the dorsal column fibers to subsequent depolarizing pulses.
    Type: Grant
    Filed: May 7, 2002
    Date of Patent: January 6, 2004
    Assignee: Medtronic, Inc.
    Inventor: Jan Holsheimer
  • Patent number: 6614604
    Abstract: An apparatus and method for magnifying visual media such as a map is disclosed. The apparatus has three main elements: a lens having a focal length, a visual media positioning assembly and a collapsible positioning assembly for positioning the lens with respect to the visual media positioning assembly. The lens is preferably a convex lens and provides magnification of a piece of visual media. The visual media assembly positions and protects a piece of visual media. The collapsible positioning assembly positions the lens a distance above the visual media so that the visual media is located closer to the lens than the lens' focal length. As a result, a magnified virtual image of the visual media is created.
    Type: Grant
    Filed: April 10, 2000
    Date of Patent: September 2, 2003
    Inventor: Jodi D. Budde
  • Patent number: 6592571
    Abstract: A pump for pumping drugs, medicaments or other liquids is disclosed in one embodiment having suture loops co-extensive with the outside surface of the pump. At least one depression is formed in the outside surface of the pump. A wire co-extensive with the outer dimensions of the pump passes over the depression forming a space between the wire and the outside surface of the pump in the depression. In this position, the wire forms a suture loop. The surgeon, when suturing the pump of the present invention in place within a pocket of tissue or other similar location, places a suture between the wire and the outside surface of the pump in the depression to secure the pump. In another embodiment, depressions are created in a pump and a soft material is placed in and attached to the depressions. A suture may then be placed through the material of the soft material and the tissue of the patient in a pocket in the tissue of the patient to affixed the pump in the pocket.
    Type: Grant
    Filed: May 24, 2000
    Date of Patent: July 15, 2003
    Assignee: Medtronic, Inc.
    Inventors: Maurice Theodore Yvonne Verbeek, Frans Philippens
  • Patent number: 6503242
    Abstract: A method and apparatus for treating Alzheimer's disease is disclosed. The method comprises delivering indomethacin or nonsteroidal anti-inflammatory agents having cyclooxygenase inhibitor action directly to the hippocampus or the lateral ventricle through an implanted catheter. The catheter has a flexible distal end that is implanted directly in the hippocampus or lateral ventricle as the preferred embodiment. The distal end has either a porous tip or a closed end. Where the distal end is closed, or a plurality of elution holes are present indomethacin is delivered to the hippocampus or lateral ventricle through either the porous tip or the elution holes.
    Type: Grant
    Filed: March 30, 2000
    Date of Patent: January 7, 2003
    Assignee: Medtronic, Inc.
    Inventor: Dennis D. Elsberry
  • Patent number: 6421566
    Abstract: A system and method is described for preferentially stimulating dorsal column fibers while avoiding stimulation of dorsal root fibers. The invention applies hyperpolarizing pre-pulses and depolarizing pre-pulses to neural tissue, such as spinal cord tissue, through a lead placed over the spinal cord having the electrodes arranged on a line approximately transverse to the axis of the spine. To increase the threshold needed to stimulate dorsal root fibers, the anodal pulse given by each lateral contact of the electrodes has to be preceded by a depolarizing pre-pulse and simultaneously, the central electrode contact gives a hyperpolarizing pre-pulse, thereby reducing the stimulation threshold for the dorsal column fibers to subsequent depolarizing pulses.
    Type: Grant
    Filed: June 12, 2000
    Date of Patent: July 16, 2002
    Assignee: Medtronic, Inc.
    Inventor: Jan Holsheimer
  • Patent number: 6415823
    Abstract: An insert is disclosed that is placed in the slit in a slit tipped catheter during storage of the catheter. This insert prevents opposite of the slit from contacting and forming bonds that tend to close the slit. When the catheter is to be used, the insert is removed and the catheter is used in its intended way.
    Type: Grant
    Filed: April 30, 1999
    Date of Patent: July 9, 2002
    Assignee: Medtronic, INC
    Inventors: Jeffrey A. Vasek, Lori Cone Speckman
  • Patent number: 6371464
    Abstract: A method of making a spring are described. The spring is made by etching or cutting at least one spiral arm in a flat substrate leaving residual material around the arm. The intermediate residual material is either pushed or lifted to form a conical spring.
    Type: Grant
    Filed: May 25, 2000
    Date of Patent: April 16, 2002
    Assignee: Medtronic, Inc.
    Inventors: Leonard Porche, William Jeff Bertrand, Mitchell Solis
  • Patent number: 6374140
    Abstract: The present invention discloses techniques for preventing a possible onset of a seizure using a sensor, a signal generator and at least one implantable electrode. The electrodes are positioned to stimulate the olfactory nervous system. The sensor senses a parameter of the body indicative of the possible onset of a seizure. The sensor generates a sensing signal which is processed and an algorithm is utilized to determine whether the sensing signal shows a pattern indicative of a possible seizure onset. If such a pattern is recognized, the signal generator provides electrical stimulation via electrodes to generate an olfactory sensory stimulus. The patient is thereby alerted, the electrical activity of the brain is desynchronized and the likelihood of a seizure occurring is reduced.
    Type: Grant
    Filed: April 30, 1998
    Date of Patent: April 16, 2002
    Assignee: Medtronic, Inc.
    Inventor: Mark T. Rise
  • Patent number: 6360784
    Abstract: A device and method for aseptically filling high pressure reservoirs in medicament pumps is disclosed. The device preferably includes a filter, a connector having a one-way valve and a filling tube with a terminal needle. The filter is connectable to a pharmacy prepared syringe containing a drug to be transferred to the reservoir of the IDIP. The filter is connected to the connector. The connector has a first and a second inlet port fluidly connected to an outlet port. A one-way valve is located in the connector “upstream” of the point where the two inlet ports connect to the outlet port. The filling tube is connectable to the outlet port. In use, a pharmacy syringe is connected to the first inlet port. A filling syringe is connected to the second inlet port. The filling tube is connected to the outlet port. The terminal needle of the filling tube is passed through the patient's skin and into the IDIP.
    Type: Grant
    Filed: December 22, 1999
    Date of Patent: March 26, 2002
    Assignee: Medtronic, Inc.
    Inventors: Frans Philippens, Craig F. Borchard, Jill Guimont, Tim Hauch, Dan Sheehan, Robert Spencer, Mary Robischon, Joanna Pierce, Patrick Johnson
  • Patent number: 6358248
    Abstract: An electrocautery device is disclosed. In accordance with one aspect of the invention, the electrocautery electrode/tip is provided with a hollow, conductive tube terminating at its distal end in a ball point type tip. Fluid, preferably conductive fluid, is applied to the proximal end of the hollow electrode/tip, and expelled from the distal end thereof during electrocautery. The ball point distal tip allows the distal tip to be directly applied to the tissue and “rolled” or slid along the tissue. This allows the distal tip to be moved across the tissue without dragging or snagging on the tissue. In addition, the conductive fluid expelled from the distal tip further lubricates the distal tip as it moves across the tissue. If conductive fluid is used, the conductive fluid emanating from the electrode/tip conducts the RF electrocautery energy away from the distal tip so that it is primarily the fluid, rather than the distal tip that actually accomplishes the cauterizing of tissue.
    Type: Grant
    Filed: May 26, 2000
    Date of Patent: March 19, 2002
    Assignee: Medtronic, Inc.
    Inventors: Peter M. J. Mulier, Michael F. Hoey
  • Patent number: 6302990
    Abstract: An infusion catheter for delivering drugs or other agents to selected sites in an organism, such as a human. In an alternate embodiment, a catheter system is disclosed having an infusion catheter and a pump that may be implanted or disposed outside the organism. In either embodiment, the free end of the catheter bears a rounded tip that has at least one elution hole for discharging an agent or drug to a selected site. The catheter has a tubular inner liner that is integral with the tip. The inner liner and tip are formed from a drug compatible polymeric material that is relatively nonporous and unreactive with the agent to be infused. A biocompatible flexible elastomeric tubular jacket surrounds the inner liner and a portion of the tip excluding that portion containing the elution hole or holes.
    Type: Grant
    Filed: March 2, 2000
    Date of Patent: October 16, 2001
    Assignee: Medtronic, Inc.
    Inventor: Timothy S. Nelson
  • Patent number: 6264921
    Abstract: A fluid delivery system and a propellant therefor. The propellant comprises a mixture of a plurality of substances, the precise by-weight or by-molar combination of which is used to set the propellant pressure within a desirable pressure range. At least one of the plurality of propellant substances is a relatively higher vapor pressure fluid; and at least one of the plurality of propellant substances is a relatively lower vapor pressure fluid.
    Type: Grant
    Filed: April 30, 1996
    Date of Patent: July 24, 2001
    Assignee: Medtronic, Inc.
    Inventors: Bruce C. Johnson, Dennis Norgon, Paul Kratoska
  • Patent number: 6263237
    Abstract: Techniques using one or more drugs and/or electrical stimulation for treating an anxiety disorder by means of an implantable signal generator and electrode and/or an implantable pump and catheter. A catheter is surgically implanted in the brain to infuse the drugs, and one or more electrodes may be surgically implanted in the brain to provide electrical stimulation.
    Type: Grant
    Filed: February 14, 2000
    Date of Patent: July 17, 2001
    Assignee: Medtronic, Inc.
    Inventor: Mark T. Rise
  • Patent number: 6249703
    Abstract: A patient programmer for facilitating patient control over an implanted medical device, such as an implanted spinal cord stimulator or the like, is disclosed. A programmer in accordance with the present invention is a portable, light-weight, easy to use patient programmer. The programmer enables a patient to control the operation of his or her implanted device outside of a clinical setting. The programmer incorporates features which ensure that users of varying ages, education levels, dexterity levels, physical and mental health will be able to safely control the operation of their implanted devices, within predefined limits established by a physician or clinician. Circuitry is provided for avoiding battery depletion and/or undesired programmer/implanted device communication in the event that the programmer's key is accidentally depressed (for example, due to being jammed into a purse or pocket) or is depressed repeatedly or continuously over an extended period of time.
    Type: Grant
    Filed: July 8, 1994
    Date of Patent: June 19, 2001
    Assignee: Medtronic, Inc.
    Inventors: David J. Stanton, Gregory A. Hrdlicka, Charles M. Meyerson, Todd A. Kallmyer
  • Patent number: 6176242
    Abstract: Techniques using one or more drugs, electrical stimulation or both to treat depression or manic depression by means of an implantable signal generator and electrode and/or an implantable pump and catheter. A catheter is surgically implanted in selected sites in the brain to infuse the drugs, and one or more electrodes are surgically implanted in the brain at selected sites to provide electrical stimulation.
    Type: Grant
    Filed: April 30, 1999
    Date of Patent: January 23, 2001
    Inventor: Mark T. Rise
  • Patent number: 6171082
    Abstract: A peristaltic pumping mechanism is provided with a non-permeable peristaltic circuit comprising two strips of thin metal laser bonded at their edges to form a tube. In one embodiment, the non-permeable tubing takes the form of a continuous loop having input and output ports. In another embodiment, the tubing is open and generally U-shaped. In still another embodiment, a dual-tube circuit is provided, wherein a central, metal tube is disposed within an outer elastomeric tube having an inner diameter larger than the outer dimension of the metal tube. The elastomeric tube supports the metal tube only at the ends of the circuit, enabling the metal tube to “float” within the elastomeric tube.
    Type: Grant
    Filed: January 22, 1997
    Date of Patent: January 9, 2001
    Assignee: Medtronic, Inc.
    Inventors: Doulas O. Hankner, Reginald D. Robinson, Dennis D. Elsberry
  • Patent number: 6132384
    Abstract: An implantable sensing device includes a sensing element and a mounting element. The mounting element has a first end and a second end with a longitudinal axis therethrough. The sensing element is positioned at the first end of the mounting element with the mounting element having a length that is adjustable along the longitudinal axis. The mounting element includes a sleeve having a first open end and a second open end with the longitudinal axis therethrough. The sensing element is positioned in the second open end and includes a lead body connected thereto extending through the second open end. The sleeve includes an outer sleeve member coupled for adjustment along the longitudinal axis with respect to an inner sleeve member. Further, the mounting element may include a flexible element about the first open end extending outwardly relative to the longitudinal axis and a flange element extending outwardly relative to the longitudinal axis from at least a portion of the second end.
    Type: Grant
    Filed: June 26, 1996
    Date of Patent: October 17, 2000
    Assignee: Medtronic, Inc.
    Inventors: Mark A. Christopherson, John L. Sommer, Johann J. Neisz
  • Patent number: 6128537
    Abstract: Techniques using one or more drugs and/or electrical stimulation for treating an anxiety disorder by means of an implantable signal generator and electrode and/or an implantable pump and catheter. A catheter is surgically implanted in the brain to infuse the drugs, and one or more electrodes may be surgically implanted in the brain to provide electrical stimulation.
    Type: Grant
    Filed: May 1, 1997
    Date of Patent: October 3, 2000
    Assignee: Medtronic, Inc
    Inventor: Mark T. Rise