Abstract: Disclosed is a polymerizable complex containing a covalently attached nucleic acid molecule which, under appropriate conditions, is capable of copolymerization with a second polymerizable ethylene-containing monomer unit to form a polymerized layer. The polymerized layer containing attached nucleic acid is useful in a variety of contexts including, for example, hybridization assays. The polymerized layer containing the covalently attached nucleic acid molecule can be formed into a variety of shapes, or attached to a formed material through appropriate chemistry.
Type:
Grant
Filed:
October 30, 1998
Date of Patent:
January 30, 2001
Assignee:
Mosaic Technologies, Inc.
Inventors:
T. Christian Boles, Stephen J. Kron, Christopher P. Adams