Patents Represented by Attorney, Agent or Law Firm Diane E. Furman
  • Patent number: 5674371
    Abstract: A process for providing a variety of light to medium colors of anodized aluminum or aluminum alloy which comprises the steps of anodizing an aluminum or aluminum alloy workpiece in an aqueous strong acid electrolyte solution such as a sulfuric acid solution by application of direct current at a current density of 5 to about 25 amperes per square foot and a temperature of from 55.degree. F. to 90.degree. F. to form on the workpiece a porous anodic oxide film having a thickness of at least about 3 microns; subjecting the resulting anodized workpiece to alternating current at a voltage of about 5 to about 25 volts for about 1 to 25 minutes in an aqueous strong acid electrolyte solution such as a sulfuric acid solution comprising about 1 to 15 volume percent of an organic carboxylic acid containing at least one reactive group in the alpha-position, wherein said reactive group is a hydroxy, amino, keto or carboxyl group; and electrolytically coloring the workpiece.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: October 7, 1997
    Assignee: Clariant Finance (BVI) Limited
    Inventor: Pinakin Patel
  • Patent number: 5599536
    Abstract: A method for ameliorating or suppressing the acute phase response in a patient receiving IL-6 treatment comprises co-administering with the IL-6 an effective amount of granulocyte colony stimulating factor.
    Type: Grant
    Filed: December 13, 1993
    Date of Patent: February 4, 1997
    Assignee: Sandoz Ltd.
    Inventor: Laurie A. Myers
  • Patent number: 5578301
    Abstract: A method for reducing or suppressing the acute phase response in a patient receiving IL-6 treatment which comprises co-administering with the IL-6 an effective amount of granulocyte macrophage colony stimulating factor (GM-CSF).
    Type: Grant
    Filed: December 14, 1993
    Date of Patent: November 26, 1996
    Assignee: Sandoz Ltd.
    Inventor: Laurie A. Myers
  • Patent number: 5573653
    Abstract: An improved electrochemical process for thiocyanating aminobenzene compounds (e.g., 3,4-dichloroaniline), and in particular a process for preparing 2-aminobenzothiazole compounds, is disclosed which provides attractive yields under relatively favorable temperature conditions, and with reduced or minimal cyanide formation. In a further aspect, use of quaternary ammonium salts in the thiocyanation medium has been found to inhibit cathodic corrosion.
    Type: Grant
    Filed: April 18, 1995
    Date of Patent: November 12, 1996
    Assignee: Sandoz Ltd.
    Inventor: Baldev K. Bandlish
  • Patent number: 5538752
    Abstract: Compositions comprising melanin or melanin precursors are useful for preventing or controlling decay of substrates such as cellulosic and other porous organic substrates. The compositions provide useful wood preservatives, wound dressings, and the like. In one embodiment, the compositions comprise melanin complexed with metal ions, particularly copper. The compositions may be applied as penetrating or surface treatments. Certain melanins are also particularly useful for removing metal ions from liquids.
    Type: Grant
    Filed: February 13, 1995
    Date of Patent: July 23, 1996
    Assignees: Regents of the Univ. of Minnesota, Sandoz Ltd.
    Inventors: Robert A. Blanchette, Theresa S. Brush, Roberta L. Farrell
  • Patent number: 5405532
    Abstract: The invention relates to a process for treating industrial waste water which comprises either: (a) pre-treating the waste water with at least two different pre-treatments selected from adsorption, membrane filtration and oxidation and then, biologically purifying the waste water or, (b) neutralizing and biologically purifying the waste water and then after-treating the waste water either by membrane filtration in combination with adsorption or oxidation or, by oxidation optionally in combination with adsorption or filtration on a nanofiltration membrane or, by filtration on a nanofiltration membrane.
    Type: Grant
    Filed: April 29, 1994
    Date of Patent: April 11, 1995
    Assignee: Sandoz Ltd.
    Inventors: Richard Loew, Wolfgang Samhaber, Anton Wyss
  • Patent number: 5403593
    Abstract: Therapeutically active sustained release dosage forms are described which are prepared from compositions which comprise (A) a hydrophilic cellulose ether polymer or mixtures thereof as a binder matrix material, (B) a granulating medium selected from the group consisting of a lipid component, polyethylene glycol polymers, and mixtures thereof, said granulating medium having a melting range higher than about 30.degree. C., and (C) a therapeutically active medicament, said components being in melt association. The compositions are prepared by a melt granulation process.
    Type: Grant
    Filed: March 31, 1992
    Date of Patent: April 4, 1995
    Assignee: Sandoz Ltd.
    Inventor: Alan E. Royce
  • Patent number: 5374455
    Abstract: Aluminum oxide sealant compositions, concentrates, and processes employing the same are described which comprise an alkaline earth metal salt and certain sulfonated compounds. Unexpected improvements in seal quality are obtained using the compositions of the invention, and in the substantial absence of smut formation. Advantageously, the aqueous sealant compositions of the invention may be cobalt and nickel-free, can be prepared from tap water, and can be employed at temperatures below the boiling point.
    Type: Grant
    Filed: December 8, 1993
    Date of Patent: December 20, 1994
    Assignee: Sandoz Ltd.
    Inventors: Pinakin Patel, Richard L. Ranieri
  • Patent number: 5362317
    Abstract: Aluminum oxide sealant compositions, concentrates, and processes employing the same are described which comprise an alkaline earth metal salt and certain sulfonated compounds. Unexpected improvements in seal quality are obtained using the compositions of the invention, and in the substantial absence of smut formation. Advantageously, the aqueous sealant compositions of the invention may be cobalt and nickel-free, can be prepared from tap water, and can be employed at temperatures below the boiling point.
    Type: Grant
    Filed: July 15, 1993
    Date of Patent: November 8, 1994
    Assignee: Sandoz Ltd.
    Inventors: Pinakin Patel, Richard L. Ranieri
  • Patent number: 5356896
    Abstract: A pharmaceutical dosage form comprising an HMG-CoA reductase inhibitor compound, e.g., fluvastatin sodium, is disclosed which is stabilized against pH-related degradation by an alkaline stabilizing medium capable of imparting a pH of at least 8 to an aqueous solution or dispersion of the composition.
    Type: Grant
    Filed: December 22, 1992
    Date of Patent: October 18, 1994
    Assignee: Sandoz Ltd.
    Inventors: Mohan B. Kabadi, Richard V. Vivilecchia
  • Patent number: 5308492
    Abstract: The invention relates to a process for treating industrial waste water which comprises either: (a) pretreating the waste water with at least two different pretreatments selected from adsorption, membrane filtration and oxidation and then, biologically purifying the waste water or, (b) neutralizing and biologically purifying the waste water and then after-treating the waste water either by membrane filtation in combination with adsorption or oxidation or, by oxidation optionally in combination with adsorption or filtration on a nanofiltration membrane or, by filtration on a nanofiltration membrane.
    Type: Grant
    Filed: June 3, 1991
    Date of Patent: May 3, 1994
    Assignee: Sandoz Ltd.
    Inventors: Richard Loew, Wolfgang Samhaber, Anton Wyss
  • Patent number: 5273758
    Abstract: Polyethylene oxide polymer is employed as a directly compressible binder matrix for therapeutically active dosage forms. Advantageously, the polyethylene oxide has an adjustable rate control effect on the release of medicament from the dosage form, enabling in particular the preparation of sustained release dosage forms.
    Type: Grant
    Filed: April 13, 1992
    Date of Patent: December 28, 1993
    Assignee: Sandoz Ltd.
    Inventor: Alan E. Royce
  • Patent number: 5266173
    Abstract: An improved process for reducing aromatic nitro compounds to form the corresponding aromatic amine compounds, and intermediates therefore, and a reducing agent therefor, are disclosed. According to the process, a titanium(IV)oxy salt such as titanium(IV) oxysulfate is electrochemically reduced to form a titanium(III)oxy reducing agent, which can be employed to chemically reduce the aromatic nitro compounds, and the resulting re-oxidized titanium salts may be recycled to the electrochemical reduction step of the process. The titanium(III)oxy salt product is highly soluble in strong acid solutions and exhibits improved oxidation stability.
    Type: Grant
    Filed: May 28, 1991
    Date of Patent: November 30, 1993
    Assignee: Sandoz, Ltd.
    Inventors: Baldev K. Bandlish, Robert V. Casciani
  • Patent number: 5189111
    Abstract: Water-dilutable side-chain-containing vinylic copolymers comprising groups (.gamma.) of the formula--X--Alk--Y-- (I),whereinAlk signifies alkylene with 2-6 carbon atoms or hydroxysubstituted alkylene with 3-6 carbon atoms or alkylene with 4-6 carbon atoms, interrupted by --O--,X signifies a basic amino group or an ammonium group andY signifies a basic --NH-group or an acid adduct thereof,one of X and Y being further bound to an optionally substituted aliphatic or heteroaromatic hydrocarbon radical and the other to hydrogen or an optionally substituted aliphatic hydrocarbon radical, as a constituent of a least some of the side-chains and at least one mole % of the comonomer units constituting the copolymer bearing such (.gamma.)-containing side-chains - which are obtainable by copolymerization of corresponding comonomers or by amino-alkylation of corresponding starting polymers - are particularly suitable as precipitating and/or flocculating agents, e.g.
    Type: Grant
    Filed: January 4, 1989
    Date of Patent: February 23, 1993
    Assignee: Sandoz Ltd.
    Inventor: Bernard Danner
  • Patent number: 5189164
    Abstract: A process for synthesizing syn-(E)-3,5-dihydroxy-7-substituted hept-6-enoic and heptanoic acids and derivatives and intermediates thereof from the corresponding keto-hydroxy compounds, which process comprises: providing a reaction medium comprising sodium borohydride and an alkoxydialkylborane compound; treating the keto-hydroxy compound with said reaction medium under conditions wherein a cyclic boronate ester is formed; and cleaving the cyclic boronate ester to obtain the dihydroxy product.The product compounds, or derivatives thereof, are useful as anti-atherosclerotic agents.
    Type: Grant
    Filed: February 20, 1990
    Date of Patent: February 23, 1993
    Assignee: Sandoz Ltd.
    Inventors: Prasad K. Kapa, Kau-Ming Chen
  • Patent number: 5039416
    Abstract: The invention relates to a process for treating industrial waste water which comprises either: (a) pre-treating the waste water with at least two different pre-treatments selected from adsorption, membrane filtration and oxidation and then, biologically purifying the waste water or, (b) neutralizing and biologically purifying the waste water and then after-treating the waste water either by membrane filtration in combination with adsorption or oxidation or, by oxidation optionally in combination with adsorption or filtration on a nanofiltration membrane or, by filtration on a nanofiltration membrane.
    Type: Grant
    Filed: May 3, 1989
    Date of Patent: August 13, 1991
    Assignee: Sandoz Ltd.
    Inventors: Richard Loew, Wolfgang Samhaber, Anton Wyss
  • Patent number: 5021132
    Abstract: A process is disclosed for electrochemically treating p-nitrotoluene-2-sulfonic acid salts under oxidizing conditions to form 4,4'-dinitrostilbene-2,2'-disulfonic acid or the salts thereof. The process provides satisfactory yields of the stilbene compound while enabling substantial recycling of reaction materials. Substantial benefits are obtained when lithium hydroxide is employed in the reaction medium, including recovery of product of high purity, and improved recovery and recycling of lithium to the process.
    Type: Grant
    Filed: August 7, 1990
    Date of Patent: June 4, 1991
    Assignee: Sandoz Ltd.
    Inventor: Baldev K. Bandlish
  • Patent number: 4941983
    Abstract: A fluid loss additive for oil-based well-working fluids, the fluid loss additive comprisingthe product of mixing in an oil or oil based liquid,(i) lignite or humic acid(ii) (a) an oil soluble or oil dispersible amine or amine salt;(b) an aliphatic amide or hydroxyamide, or a cyclic derivative thereof, containing no primary or secondary amine or amine salt groups; and/or(c) an oil soluble or oil dispersible amine salt containing at least one C.sub.1-22 alkyl, C.sub.2-22 alkenyl or C.sub.1-22 acyl group partially or fully salted with phosphoric acid; and(iii) a dimer and/or trimer fatty acid.
    Type: Grant
    Filed: August 29, 1988
    Date of Patent: July 17, 1990
    Assignee: Sandoz Ltd.
    Inventors: Jacqueline A. Coates, John M. Farrar, Margaret H., all of Graham
  • Patent number: 4835169
    Abstract: The invention provides a method of combatting fungal diseases with the aid of(a) the compound of formula I ##STR1## and (b) carbendazim,and fungicidal compositions comprising said compounds.
    Type: Grant
    Filed: December 7, 1987
    Date of Patent: May 30, 1989
    Assignee: Sandoz Ltd.
    Inventor: Hans Wiedmer
  • Patent number: 4593080
    Abstract: According to the present invention, an improved method for providing acrylic copolymer resins is provided in which the polymerization solvent comprises a blend of methyl isobutyl ketone and certain alkyl-substituted benzene solvents. The monomers comprise hydroxy-substituted alkyl (meth)acrylate monomers and non-hydroxy substituted alkyl (meth)acrylate monomers, and the process provides an improved method for forming low molecular weight acrylic resins useful as components in acrylic coatings. The polymerization solvent can remain in the resin to become a solvent employed in the higher solids coating containing the thus-formed acrylic resins and provides improved electrical resistivity, improved solvency and decreased surface tensions over prior art polymerization solvents.
    Type: Grant
    Filed: October 24, 1984
    Date of Patent: June 3, 1986
    Assignee: Exxon Research & Engineering Co.
    Inventors: Constantine J. Bouboulis, Irving Kuntz