Patents Represented by Attorney Donald C. Lewis

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  • Encoded combinatorial chemical libraries
    Patent number: 5573905
    Abstract: The present invention describes an encoded combinatorial chemical library comprised of a plurality of bifunctional molecules having both a chemical polymer and an identifier oligonucleotide sequence that defines the structure of the chemical polymer. Also described are the bifunctional molecules of the library, and methods of using the library to identify chemical structures within the library that bind to biologically active molecules in preselected binding interactions.
    Type: Grant
    Filed: March 30, 1992
    Date of Patent: November 12, 1996
    Assignee: The Scripps Research Institute
    Inventors: Richard Lerner, Kim Janda, Sydney Brenner