Abstract: In accordance with the present invention an ink formulation capable of monitoring steam, dry heat and ethylene oxide gas sterilization processes is disclosed. The formulation comprises selected substituted pyridenes, quinolines or isoquinolines as the active compound in combination with a nitrocellulose solution and a solvent.

Abstract: A penile clamp has a flexible member for encircling the shaft of the penis. It can be tightened around the penis. The arrangement and construction of the flexible member is such that such tightening causes a localized pressure to be applied to a central portion of the underside of the penile shaft.

Abstract: A synthetic plastic bag for containing liquids, e.g., urine, has a plastic outlet tube. It is manufactured by a first step of seam welding the tube between two superposed bag walls. In a subsequent step, an encircling sleeve is slid over the tube to a position where it contains within it the portions of the bag walls on either side of the tube. Thirdly, this sleeve is compressed onto the tube by a crimping operation conducted with the crimping force applied in a direction substantially parallel to the plane in which the bag walls lie. The tube may be part of a tap or other outlet fitting such as a push-pull tap.

Abstract: A releasable catheter retaining device is mounted on a pad of medical grade skin adhesive material. The device has a flange with a central hole, and a post extends from a surface of the flange opposite to the pad. An elongated tab extends from the post, there being a slot in the post for receiving the free end of the tab. With this arrangement, the tab can be passed through the slot after encircling a catheter which extends through the hole, in order to grip the catheter and to retain it in position.

Abstract: Boronic acid adducts of radioactive isotopes of rhenium dioxime complexes are useful for labeling biologically active compounds as agents for radiotherapy. These boronic acid adducts of radioactive isotopes of rhenium dioxime complexes have the formulaI. ReX(Y).sub.3 Z,whereinX is an anion;Y is a vicinal dioxime having the formulaII. ##STR1## or a pharmaceutically acceptable salt thereof, and R.sub.1 and R.sub.2 are each independently hydrogen, halogen, alkyl, aryl, amino or a 5 or 6-membered nitrogen or oxygen containing heterocycle, or together R.sub.1 and R.sub.2 are --CR.sub.8 R.sub.9).sub.n --wherein n is 3, 4, 5 or 6 and R.sub.8 and R.sub.9 are each independently hydrogen or alkyl;Z is a boron derivative having the formulaIII. B--R.sub.3wherein R.sub.3 is hydroxy, alkyl, alkenyl, cycloalkyl, cycloaLkenyl, alkoxy, carboxyalkyl, carboxyalkenyl, hydroxyalkyl, hydroxyalkenyl, alkoxyalkyl, alkoxyalkenyl, haloalkyl, haloalkenyl, aryl, arylalkyl or (R.sub.4 R.sub.5 N)-alkyl and R.sub.4 and R.sub.

Abstract: A urostomy appliance has one part which is attachable to the body of the wearer by a pad of medical grade adhesive. The pad has a central hole, and, on its side remote from the skin of the wearer, a coupling element. The first part above mentioned is constructed to co-operate with a second part consisting of a single piece of moulded plastics material. The second part includes a coupling element constructed for a snap fit or a push fit engagement with the first coupling element. Moreover, it has a cover wall in the shape of a dome and an outlet pipe.

Abstract: A new process for preparing 2-methoxyisobutylisonitrile is described. 2-methoxyisobutylisonitrile is used in the preparation of Tc-99m hexakis (2-methoxyisobutylisonitrile). This cationic complex is useful as a myocardial perfusion agent.

Abstract: Disclosed are compounds having the formula ##STR1## wherein Prot is a hydroxyl protecting group. The compounds are useful as intermediates in the preparation of compounds of the formula ##STR2## which in turn are useful as antiviral agents.

Abstract: Zofenopril, and pharmaceutically acceptable salts thereof, can be used for the treatment of rheumatoid arthritis.

Abstract: A bag 10 for containing liquids is formed by welding together two plastic sheets around their peripheries and includes a neck portion 11 for connection to an outlet. An outlet tube 13 is partially inserted into the neck portion leaving a part of the tube with an upstanding seal member 17 outside the neck portion. A sleeve 18 is passed over the neck portion and the sleeve is shrunk into place, urging the neck portion 11 into tight engagement with the outlet tube 13 and effecting a seal between the sleeve 18 and the seal member 17 on the outlet tube 13.

Abstract: Compounds of the formula ##STR1## and their pharmaceutically acceptable salts wherein Z completes a cycloalkyl ring, a substituted cycloalkyl ring, a cycloalkenyl ring, a substituted cycloalkenyl ring or a saturated heteroalkyl ring; R.sub.2 is lower alkyl, aralkyl or aminoalkyl and X is an amino or imino acid. The compounds possess angiotensin converting enzyme inhibition activity.

Abstract: Leukotriene biosynthesis in macrophage cells is inhibited by compounds having the formula ##STR1## and pharmaceutically acceptable salts thereof, wherein R.sub.1 and R.sub.2 are each hydrogen and R.sub.3 is alkyl or arylalkyl;R.sub.1 and R.sub.3 are each hydrogen and R.sub.2 is arylmethyl or arylcarbonyl;R.sub.1 is methyl, R.sub.2 is arylmethyl and R.sub.3 is hydrogen; orR.sub.1 is alkyl of seven or more carbons or arylalkyl and R.sub.2 and R.sub.3 are each hydrogen.

Abstract: Antibacterial activity is exhibited by .beta.

Abstract: Hypotensive activity is exhibited by compounds having the formula ##STR1## and pharmaceutically acceptable salts thereof wherein R.sub.1 is hydrogen or alkyl;R.sub.2 and R.sub.3 are each independently phenyl, substituted phenyl, cycloalkyl, or R.sub.2 is hydrogen and R.sub.3 is heteroaryl;R.sub.4 and R.sub.5 are the same or different and each is hydrogen, hydroxy, alkoxy, alkanoyl or alkyl;R.sub.6 is hydrogen or alkyl; andn is 1, 2, 3 or 4; with the proviso that if R.sub.2 and R.sub.3 are each phenyl, at least one of R.sub.1, R.sub.4, R.sub.5 and R.sub.6 is other than hydrogen.

Abstract: Antibacterial activity is exhibited by 3-acylamino-2-oxoazetidines having in the 1-position an activating group of the formula ##STR1## wherein R is ##STR2## and R.sub.

Abstract: Antibacterial activity is exhibited by .beta.-lactams having a sulfonic acid salt substituent in the 1-position and an amino or acylamino substituent in the 3-position.

Abstract: Antibacterial activity is exhibited by 2-azetidinones having a 3-acylamino substituted and having an activating group in the 1-position of the formula ##STR1## wherein A.sub.1 is a single bond, ##STR2## and A.sub.

Abstract: Vasodilating activity is exhibited by compounds having the formula ##STR1## n is 2 or 3; X is oxygen or sulfur,R.sub.1 and R.sub.2 are each independently hydrogen alkyl, cycloalkyl, or allyl, or R.sub.1 and R.sub.2 together with the nitrogen atom to which they are attached are pyrrolidinyl, piperidinyl, or morpholinyl;R.sub.3 is alkyl, alkoxy, halogen, trifluoromethyl, or nitro;R.sub.4 is hydrogen, halogen, trifluoromethyl, or nitro; andR.sub.5 and R.sub.6 are each independently alkyl or cycloalkyl or R.sub.5 and R.sub.6 together with the nitrogen atom to which they are attached are pyrrolidinyl, piperidinyl, or morpholinyl.