Patents Represented by Attorney Edward A. Conroy, Jr.

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  • Method of treating hyperlipidemia with 4-(monoalkylamino)benzoic acid amides
    Patent number: 4485105
    Abstract: This disclosure describes a method of treating hyperlipidemia and atherosclerotic lesions with 4-(monoalkylamino)benzoic acid amides and compositions therefor.
    Type: Grant
    Filed: May 30, 1980
    Date of Patent: November 27, 1984
    Assignee: American Cyanamid Company
    Inventor: Robert G. Shepherd
  • Arylglyoxals useful as hypoglycemic agents
    Patent number: 4485114
    Abstract: Arylglyoxals which are new compounds, which are active as hypoglycemic agents.
    Type: Grant
    Filed: January 20, 1983
    Date of Patent: November 27, 1984
    Assignee: American Cyanamid Company
    Inventors: Middleton B. Floyd, Jr., Vern G. DeVries
  • Arylglyoxals
    Patent number: 4474809
    Abstract: Arylglyoxals which are new compounds active as hypoglycemic agents.
    Type: Grant
    Filed: January 20, 1983
    Date of Patent: October 2, 1984
    Assignee: American Cyanamid Company
    Inventors: Middleton B. Floyd, Jr., Vern G. DeVries
  • Arylglyoxals and their pharmaceutical use
    Patent number: 4474810
    Abstract: Arylglyoxals which are new compounds, active as hypoglycemic agents.
    Type: Grant
    Filed: January 27, 1983
    Date of Patent: October 2, 1984
    Assignee: American Cyanamid Company
    Inventors: Middleton B. Floyd, Jr., Vern G. DeVries
  • Antiatherosclerotic tetrasubstituted ureas and thioureas
    Patent number: 4473579
    Abstract: Tetrasubstituted urea and thiourea compounds useful as antiatherosclerotic agents, compositions thereof and processes for their preparation.
    Type: Grant
    Filed: January 26, 1982
    Date of Patent: September 25, 1984
    Assignee: American Cyanamid Company
    Inventors: Vern G. Devries, Ransom B. Conrow
  • Process for preparing 5-imidazolyl ketones
    Patent number: 4459413
    Abstract: This disclosure describes a novel process for the preparation of 1-(lower alkyl)substituted derivatives of 6-n-propyl-8-alkylimidazo[1,5-d]-as-triazin-4(3H)-ones which are useful as anti-asthmatic agents.
    Type: Grant
    Filed: February 11, 1983
    Date of Patent: July 10, 1984
    Assignee: American Cyanamid Company
    Inventors: Sivaraman Raghu, James Salvatore, Steven L. Peake
  • 1,4-Bis(substituted-amino)-5,8-dihydroxyanthraquinones and leuco bases thereof
    Patent number: 4456552
    Abstract: This disclosure describes symmetrical 1,4-bis(substituted-amino)-5,8-dihydroxyanthraquinones useful as chelating agents and for inhibiting the growth of transplanted mouse tumors.
    Type: Grant
    Filed: March 2, 1981
    Date of Patent: June 26, 1984
    Assignee: American Cyanamid Company
    Inventors: Keith C. Murdock, Frederick E. Durr
  • Antiatherosclerotic 1-piperazine-thicarboxamides
    Patent number: 4450272
    Abstract: This disclosure describes 4-heteroaryl-1-piperazinethiocarboxamides useful in the treatment of atherosclerosis in mammals.
    Type: Grant
    Filed: May 6, 1982
    Date of Patent: May 22, 1984
    Assignee: American Cyanamid Company
    Inventors: Mila T. Du, Robert G. Shepherd
  • Substituted-6-n-propyl-8-methylimidazo[1,5-d]-as-triazin-4-(3H)-ones
    Patent number: 4447603
    Abstract: This disclosure describes new compounds and compositions of matter useful as anti-asthmatic agents and the method of meliorating asthma in mammals therewith, the novel active ingredients of said compositions of matter being certain 1-substituted-6-n-propyl-8-methylimidazo [1,5-d]-as-triazin-4(3H)-ones and/or the pharmacologically acceptable acid-addition salts thereof.
    Type: Grant
    Filed: February 4, 1981
    Date of Patent: May 8, 1984
    Assignee: American Cyanamid Company
    Inventor: Rolf Paul
  • 7-Heteroaryl[1,2,4]triazolo[1,5-a]pyrimidines
    Patent number: 4444774
    Abstract: This disclosure describes 7-heteroaryl[1,2,4]triazolo[1,5-a]pyrimidines which are useful as anxiolytic agents.
    Type: Grant
    Filed: July 29, 1982
    Date of Patent: April 24, 1984
    Assignee: American Cyanamid Company
    Inventors: John P. Dusza, Jay D. Albright
  • Method of treating depression using azabicyclohexanes
    Patent number: 4435419
    Abstract: The present invention concerns certain novel substituted 3-azabicyclo[3.1.0]hexanes and a method of treating depression and stress in a warm-blooded animal, comprising the administration of substituted 3-azabicyclo[3.1.0]hexanes.
    Type: Grant
    Filed: May 10, 1982
    Date of Patent: March 6, 1984
    Assignee: American Cyanamid Company
    Inventors: Joseph W. Epstein, Arnold C. Osterberg, Herbert J. Brabander
  • 1,4-Bis(substituted-amino)-5,8-dihydroxy-anthraquinones and leuco bases thereof
    Patent number: 4430501
    Abstract: This disclosure describes symmetrical 1,4-bis(substituted-amino)-5,8-dihydroxyanthraquinones useful as chelating agents and for inhibiting the growth of transplanted mouse tumors.
    Type: Grant
    Filed: November 2, 1981
    Date of Patent: February 7, 1984
    Assignee: American Cyanamid Company
    Inventors: Keith C. Murdock, Frederick E. Durr
  • 1-(Aminoalkylamino)-5,8-dihydroxy-4-substituted-anthraquinones
    Patent number: 4428882
    Abstract: This disclosure describes 1-(aminoalkylamino)-5,8-dihydroxy-4-substituted-anthraquinones useful as chelating agents and for inhibiting the growth of transplanted mouse tumors.
    Type: Grant
    Filed: February 24, 1982
    Date of Patent: January 31, 1984
    Assignee: American Cyanamid Company
    Inventor: Keith C. Murdock
  • 15-Deoxy-16-hydroxy-16-substituted prostanoic acids and congeners
    Patent number: 4429148
    Abstract: This disclosure describes novel 15-deoxy-16-hydroxy-16-substituted prostanoic acids and congeners thereof having utility as bronchodilators as hypotensive agents, and as agents for the control of excessive gastric secretion.
    Type: Grant
    Filed: September 25, 1981
    Date of Patent: January 31, 1984
    Assignee: American Cyanamid Company
    Inventors: Middleton B. Floyd, Jr., Martin J. Weiss, Charles V. Grudzinskas, Sow-Mei Lai Chen
  • 1-(5-Amino-4H-1,2,4-triazol-3-yl)-4-substituted-piperazines
    Patent number: 4421753
    Abstract: This disclosure describes novel 1-(5-amino-4H-1,2,4-triazol-3-yl)-4-substituted-piperazines which are useful as hypotensive agents in mammals.
    Type: Grant
    Filed: March 22, 1982
    Date of Patent: December 20, 1983
    Assignee: American Cyanamid Company
    Inventors: Andrew S. Tomcufcik, Walter E. Meyer, John P. Dusza
  • 9,10-Bis(aminoalkoxy)anthracenes
    Patent number: 4419354
    Abstract: This disclosure describes certain substituted 9,10-bis(2-aminoethoxy)anthracenes which are useful as modulators of the immune response system in warm-blooded animals and for inducing the regression of tumors in such animals.
    Type: Grant
    Filed: June 3, 1982
    Date of Patent: December 6, 1983
    Assignee: American Cyanamid Company
    Inventors: Ralph G. Child, Stanley A. Lang, Jr.
  • Method of treating tumors in warm-blooded animals
    Patent number: 4418078
    Abstract: This disclosure describes compositions of matter useful as inhibitors of transplanted mouse tumor growth, the active ingredient of said compositions of matter being 1,4-bis(3-aminopropylamino)-5,8-dihydroxyanthraquinone or the non-toxic acid-addition salts thereof.
    Type: Grant
    Filed: August 27, 1979
    Date of Patent: November 29, 1983
    Assignee: American Cyanamid Company
    Inventor: Keith C. Murdock
  • Process for preparing 1-substituted-6-n-propyl-8-methylimidazo[1,5-d]-as-triazin-4(3H)-ones
    Patent number: 4395547
    Abstract: This disclosure describes a novel process for the preparation of 1-(lower alkyl)substituted derivatives of 6-n-propyl-8-alkylimidazo[1,5-d]-as-triazin-4(3H)-ones which are useful as anti-asthmatic agents.
    Type: Grant
    Filed: February 10, 1982
    Date of Patent: July 26, 1983
    Assignee: American Cyanamid Co.
    Inventors: Sivaraman Raghu, James S. Farina, Steven L. Peake
  • Substituted phenyl-5-aminopyrazoles
    Patent number: 4393217
    Abstract: This disclosure describes novel substituted phenyl-5-aminopyrazoles useful as anxiolytic and/or anti-depressant agents.
    Type: Grant
    Filed: January 12, 1981
    Date of Patent: July 12, 1983
    Assignee: American Cyanamid Company
    Inventors: John P. Dusza, Jay D. Albright
  • 3-[(.alpha.-Substituted-benzyl]-2,3,dihydr othiazolo[3,2-a][1,3]diazacyclan-3-ol derivatives
    Patent number: 4393004
    Abstract: This disclosure describes certain novel 3-(.alpha.-substituted-benzyl)-2,3-dihydrothiazolo[3,2-a][1,3]diazacyclan- 3-ols which are useful as diuretic agents.
    Type: Grant
    Filed: January 29, 1982
    Date of Patent: July 12, 1983
    Assignee: American Cyanamid Company
    Inventors: Andrew S. Tomcufcik, William B. Wright, Jr., Joseph W. Marsico, Jr.