Abstract: A process for producing a sterile article in a sealed container during a continuous production process. In a preferred embodiment, a contact lens is immersed in an ozone-containing solution within a container during a continuous lens packaging process, and the lens and container are subsequently subjected to ultraviolet radiation. This process sterilizes the contact lens and lens container in order to maintain the contact lens in a sterile environment during shipping, handling, and storage.

Abstract: Compounds of the formula I ##STR1## in which a) X is CH and Y is N; orb) X is N and Y is CH; and in whichZ is a C.sub.1 group to which there are bonded 1-3 halogen atoms or 1-3 substituted or unsubstituted hetero atoms O, S and/or N are suitable for controlling and preventing microbial attack on plants.

Abstract: A container, composition and method for preserving treatment solutions, in which the composition includes weak and strong preservatives. The dispensing container includes media within a dispensing tip which media removes or alters the strong preservative, while allowing the weak preservative to inhibit microbial growth in the tip media. The dispensing container is especially useful in delivering to the ocular environment ophthalmic solutions which are essentially free of strong preservative which may cause patient discomfort. A dispensing container including a pH-preserved pilocarpine solution is disclosed in one embodiment.

Abstract: Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen or methyl,R.sub.2 is hydrogen, halogen, OCH.sub.3, SCH.sub.3 or CN,R.sub.3, R.sub.4, R.sub.5 are each independently of one another hydrogen, halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.2 -C.sub.5 alkoxycarbonyl, C.sub.1 -C.sub.5 alkanoyl, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 haloalkoxy, CN, NO.sub.2, or wherein two of those substituents are adjacent to each other and together are a methylenedioxy or difluoromethylenedioxy radical,K, L, M are each independently of one another CH or N (=nitrogen atom), but at least one of these three substituents is N, andY is oxygen or sulfur,are effective microbicides for controlling fungal diseases. They can be used for plant protection by themselves or as formulated compositions.

Abstract: Compounds of formula I: ##STR1## are disclosed. The compounds are photoinitiators which can be functionalized by means of ethylenic groups or can be bonded to H-active substances, in order, for example, to modify surfaces by means of photopolymerizable substances. The compounds are especially useful in the manufacture of contact lenses.

Abstract: Contact lenses formed from compounds of formula I: ##STR1## are disclosed. The compounds are photoinitiators which can be functionalized by means of ethylenic groups or can be bonded to H-active substances, in order, for example, to modify surfaces by means of photopolymerizable substances. The compounds are especially useful in the manufacture of contact lenses.

Abstract: The blister pack comprises a base portion and a cover layer. The base portion comprises a hollow chamber that contains a soft hydrophilic contact lens and a sterile aqueous preserving solution, and a substantially flat flange that extends right round the outside of the hollow chamber. The cover layer is releasably sealed to the flange in a sealing zone that extends right round the circumference of the hollow chamber. The flange comprises a grip region that extends from one side of the hollow chamber beyond the sealing zone and is covered by a corresponding grip region of the cover layer but is not sealed thereto.

Abstract: A disinfection apparatus including a container; a cap having an article-retaining means, a sealing means and a catalytic element-retaining means affixed thereto; and a catalytic element. The disinfection apparatus has particular utility in the disinfection of contact lenses with hydrogen peroxide solutions. Also disclosed are venting and sealing components, catalytic elements, molded article-retaining assemblies, and catalytic element formation methods.

Abstract: A disinfection apparatus including a container; a cap having an article-retainer, a and a catalytic element-retainer means affixed thereto; and a catalytic element. The disinfection apparatus has particular utility in the disinfection of contact lenses with hydrogen peroxide solutions. Also disclosed are venting and sealing components, catalytic elements, molded article-retaining assemblies, and catalytic element formation methods.

Abstract: Methods of deblocking a polymeric article from a mold and/or removing undesirable materials from a polymeric article by applying supercritical fluids to the polymeric article. A preferred process is the treatment of ophthalmic lenses, such as contact lenses. Supercritical fluid, composed primarily of carbon dioxide, is applied to a contact lens affixed to a mold subsequent to the polymerization step. The application of supercritical fluid (SCF) causes the lens to efficiently and consistently separate from the mold, removes undesirable materials such as unreacted monomer, oligomers, or residual solvents from the lens core, and/or cleans the lens surface of adhered debris.

Abstract: 2-Aminooxymethylenephenylacetic acid ester derivatives of the formula ##STR1## wherein Z.sub.1 and Z.sub.2 are hydrogen, halogen, hydroxy, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 haloalkoxy, C.sub.1 -C.sub.4 alkylcarbonyl, phenoxy, nitro or cyano, or Z.sub.1 and Z.sub.2, together with the linking phenyl radical, are naphthalene or hydrogenated naphthalene, and R.sub.3 is hydrogen or C.sub.1 -C.sub.12 alkyl. The compounds of this invention may be used as the free base or as a protic acid salt and are important intermediates for the manufacture of microbicides for plant protection.

Abstract: 3-Aryluracil derivatives of formula I ##STR1## wherein W is a group of the formula ##STR2## wherein the bond to the ring nitrogen atom is made via the carbon atom; wherein R.sub.1 to R.sub.9 are as defined in claim 1, are suitable as active ingredients in weed control compositions.

Abstract: A plant-microbicidal composition having synergistic action, comprising at least two active ingredient components, wherein component I is a compound selected from the group(IA) 1-[3-(2-chlorophenyl)-2-(4-fiuorophenyl)oxiran-2-ylmethyl]-1H-1,2,4-triazo le ("epoxiconazol");(IB) 4-(4-chlorophenyl)-2-phenyl-2-(1,2,4-triazol-1-ylmethyl)-butyronitrile ("fenbuconazol");(IC) 5-(4-chlorobenzyl)-2,2-dimethyl-1-(1H-1,2,4-triazol-1-ylmethyl)-cyclopenta nol ("metconazol");(ID) 2-(2,4-dichlorophenyl)-3-(1H-1,2,4-triazol-1-yl)propyl-1,1,2,2-tetrafluoro ethyl ether ("tetracon azol");(IE) .alpha.-[2-(4-chlorophenyl)ethyl]-.alpha.

Abstract: A preservative-free ophthalmic composition useful in the treatment of conditions such as dry eye comprising an aqueous solution of hydroxypropyl methylcellulose, polyethylene glycol, dextrose, potassium chloride, boric acid and sodium borate decahydrate.

Abstract: N-Phenylsulfonyl-N'-pyrimidinylureas and -thioureas of formula I ##STR1## in which X is oxygen, sulfur, SO or SO.sub.2 ; W is oxygen or sulfur; R.sub.1 is hydrogen or methyl; R.sub.2 is hydrogen, fluorine, chlorine, bromine, iodine, (X).sub.n R.sub.3, NO.sub.2, NR.sub.4 R.sub.5, ##STR2## or cyano; n is the number 0 or 1; R.sub.3 is C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkyl which is substituted by 1-4 halogen atoms, C.sub.1 -C.sub.3 alkoxy or C.sub.1 -C.sub.3 alkylthio; or C.sub.2 -C.sub.4 alkenyl or C.sub.2 -C.sub.4 alkenyl which is substituted by 1-4 halogen atoms; R.sub.4 is hydrogen, CH.sub.3 O, CH.sub.3 CH.sub.2 O or C.sub.1 -C.sub.3 alkyl; R.sub.5 is hydrogen or C.sub.1 -C.sub.3 alkyl; R.sub.6 is hydrogen, methyl or ethyl; R.sub.7 is hydrogen or methyl; Z is ##STR3## E is methine; R.sub.8 is C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkoxy, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 haloalkylthio, C.sub.1 -C.sub.4 alkylthio, halogen, C.sub.2 -C.sub.5 alkoxyalkyl, C.

Abstract: .alpha.-Amino acid amides of the formula I ##STR1## in which n is the number zero or one;R.sub.1 is C.sub.1 -C.sub.12 alkyl, which is unsubstituted or can be substituted by C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkylthio, C.sub.1 -C.sub.4 alkylsulfonyl, C.sub.3 -C.sub.8 cycloalkyl, cyano, C.sub.1 -C.sub.6 alkoxycarbonyl, C.sub.3 -C.sub.6 alkenyloxycarbonyl or C.sub.3 -C.sub.6 alkynyloxycarbonyl; C.sub.3 -C.sub.8 cycloalkyl; C.sub.2 -C.sub.12 alkenyl; C.sub.2 -C.sub.12 alkynyl; C.sub.1 -C.sub.12 halogenoalkyl or a group NR.sub.13 R.sub.14 ; in whichR.sub.13 and R.sub.14 independently of one another are hydrogen or C.sub.1 -C.sub.6 alkyl or together are tetra- or pentamethylene;R.sub.2 and R.sub.3 independently of one another are hydrogen; C.sub.1 -C.sub.8 alkyl; C.sub.1 -C.sub.8 alkyl which is substituted by hydroxyl, C.sub.1 -C.sub.4 alkoxy, mercapto or C.sub.1 -C.sub.4 alkylthio; C.sub.3 -C.sub.8 alkenyl; C.sub.3 -C.sub.8 alkynyl; C.sub.3 -C.sub.8 cycloalkyl or C.sub.3 -C.sub.8 cycloalkyl-C.sub.1 -C.sub.

Abstract: The invention relates to a novel process for the manufacture of mouldings, especially contact lenses, in which a soluble prepolymer comprising crosslinkable groups is cross-linked in solution, and also to mouldings, especially contact lenses, obtainable in accordance with that process. The present invention relates also to novel prepolymers that can be used in the process according to the invention, especially derivatives of a polyvinyl alcohol having a molecular weight of at least about 2000 that, based on the number of hydroxy groups of the polyvinyl alcohol, comprise from approximately 0.5 to approximately 80% of units of formula I ##STR1## wherein R is lower alkylene having up to 8 carbon atoms,R.sup.1 is hydrogen or lower alkyl andR.sup.

Abstract: Compounds of formula I are suitable for controlling and preventing infestation by microorganisms, insects and acarina on plants ##STR1## and their possible isomers and mixtures of isomers, whereina) X is CH.sub.2 F or CHF.sub.2,Y is CH andZ is OCH.sub.3, orb) X is CH.sub.2 F or CHF.sub.2,Y is a nitrogen atom andZ is OCH.sub.3 or NHCH.sub.3,and wherein R.sub.1 and R.sub.2 are each independently of the other hydrogen, cyano, C.sub.1 -C.sub.12 alkyl, halo-C.sub.1 -C.sub.12 alkyl, C.sub.2 -C.sub.12 alkenyl, C.sub.2 -C.sub.12 alkynyl, C.sub.3 -C.sub.6 cycloalkyl, cyclopropylmethyl, C.sub.1 -C.sub.4 alkoxy, C.sub.2 -C.sub.12 alkoxyalkyl, C.sub.1 -C.sub.4 alkoxycarbonyl, C.sub.1 -C.sub.4 alkylthio, C.sub.2 -C.sub.

Abstract: A pH controlled protein removal system and method in the substantial absence of (a) enzyme and (b) a surfactantly effective amount of a surfactant is disclosed. The method comprises contacting a substrate with a cleaning composition therefor, which compostion is substantially free of (a) enzyme and (b) surfactantly effective amount of a surfactant, for a period of time at an alkaline pH and removing said substrate from said composition.

Abstract: The present invention relates to monoclonal antibodies which are distinguished by high selectivity and affinity for metolachlor and which are therefore outstandingly suitable for use in an immunoassay for the rapid and efficient detection of metolachlor. Another aspect of the present invention relates to hybridoma cell lines which produce said monoclonal antibodies and to immunological methods for detecting metolachlor in samples of soil, water or air using said monoclonal antibodies and to the test kits which can be used within the scope of these detection methods.