Patents Represented by Attorney, Agent or Law Firm Elias J Lambiris
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Patent number: 7396670Abstract: The formation of acrylamide during heat treatment in the production of a food product is reduced by treating the raw material with an enzyme before the heat treatment. The enzyme is capable of reacting on asparagine or glutamine (optionally substituted) as a substrate or is a laccase or a peroxidase.Type: GrantFiled: October 10, 2003Date of Patent: July 8, 2008Assignee: Novozymes A/SInventors: Gitte Budolfsen, Morten Tovborg Jensen, Hans Peter Heldt-Hansen, Mary Ann Stringer
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Patent number: 7396657Abstract: Attaching a peptide extension to the C-terminal amino acid of a lipase reduces the tendency to form odor. This may lead to lipase variants with a reduced odor generation when washing textile soiled with fat which includes relatively short-chain fatty acyl groups (e.g., up to C8) such as dairy stains containing butter fat or tropical oils such as coconut oil or palm kernel oil.Type: GrantFiled: November 21, 2006Date of Patent: July 8, 2008Assignee: Novozymes A/SInventors: Signe Munk, Jesper Vind, Kim Borch, Shamkant Anant Patkar, Sanne O. Schroder Glad, Allan Svendsen
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Patent number: 7396807Abstract: The present invention is related to a method for producing a phospholipase by processing an expressed fungal peptide and to certain specified phospholipases. Furthermore the invention provides a method for producing cheese with a phospholipase.Type: GrantFiled: December 5, 2006Date of Patent: July 8, 2008Assignees: Novozymes A/S, Chr. Hansen A/SInventors: Mary Ann Stringer, Tine Muxoll Fatum, Shamkant Anant Patkar
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Patent number: 7361736Abstract: The present invention relates to xyloglucanases belonging to family 44 of glycosyl hydrolases and having a relative xyloglucanase activity of at least 30% between pH 5 and pH 8 are derived from the genus Paenibacillus especially from a strain of Paenibacillus polymyxa or Paenibacillus sp. The xyloglucanases exhibit high performance in conventional detergent compositions.Type: GrantFiled: July 22, 2004Date of Patent: April 22, 2008Assignee: Novozymes A/SInventors: Kirk Schnorr, Per Lina Jorgensen, Hanne Dela, legal representative, Martin Schulein
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Patent number: 7273738Abstract: The present invention relates to use of an anti-staling GH-61 polypeptide for preparing an edible product.Type: GrantFiled: October 1, 2003Date of Patent: September 25, 2007Assignee: Novozymes A/SInventors: Kirk Matthew Schnorr, Sara Landvik, Tina Spendler, Lars Lehmann Hylling Christensen
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Patent number: 7273745Abstract: The present invention relates to pectate lyases comprising the amino acid sequence Asn Leu Asn Ser Arg Val Pro (NLNSRVP) (amino acids 236-242 of SEQ ID NO: 2) belonging to Family 1 of polysaccharide lyases have good performance in industrial processes under neutral or alkaline conditions such as laundering and textile processing. The pectate lyase may be derivable from Bacillus species.Type: GrantFiled: November 28, 2006Date of Patent: September 25, 2007Assignee: Novozymes A/SInventors: Lene Nonboe Andersen, Hanne Dela, legal representative, Niels Erik Krebs Lange, Mads Eskelund Bjørnvad, Søren Møller, Sanne O. Schrøder Glad, Markus Sakari Kauppinen, Kirk Schnorr, Lars Kongsbak, Martin Schülein, deceased
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Patent number: 7250398Abstract: The present invention relates to polypeptides having antimicrobial activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the nucleic acid constructs as well as methods for producing and using the polypeptides.Type: GrantFiled: January 6, 2005Date of Patent: July 31, 2007Assignee: Novozymes A/SInventor: Hans-Henrik Kristensen Hogenhaug
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Patent number: 7244597Abstract: The invention relates to a method of producing ethanol by fermentation, said method comprising a secondary liquefaction step in the presence of a thermostable acid alpha-amylase or, a thermostable maltogenic acid alpha-amylase.Type: GrantFiled: November 9, 2001Date of Patent: July 17, 2007Assignees: Novozymes A/S, Novozymes North America, Inc.Inventors: Christopher Veit, Claus Felby
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Patent number: 7241463Abstract: The inventor has found that enzymatic treatment of crustaceans with lipolytic enzymes promotes the extraction of coloured pigment. Accordingly, the invention relates to a method for recovering coloured pigment, e.g. astaxanthin, and/or chitin or chitosan and/or lysolecithins from crustaceans. Lipolytic enzyme(s) may e.g. be lipase or phospholipase. The lipolytic enzyme treated crustacean material may be subjected to additional process steps, including treatment with non-lipolytic enzymes such as e.g. protease. The process of the invention provides several suitable products and several uses of such products. Furthermore, the invention also relates to the cosmetic and consumable products (feed and food (including beverages) products and additives produced therefrom.Type: GrantFiled: September 21, 2001Date of Patent: July 10, 2007Assignee: Novozymes A/SInventor: Per Munk Nielsen
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Patent number: 7238350Abstract: The present invention relates to isolated polypeptides having phytase activity, the corresponding cloned DNA sequences, a process for preparing such polypeptides, and the use thereof for a number of industrial applications. In particular, the invention relates to phytases derived from the phyllum Basidiomycota, phytases of certain consensus sequences and fungal 6-phytases.Type: GrantFiled: November 30, 2001Date of Patent: July 3, 2007Assignee: Norozymes A/SInventors: Soren Flensted Lassen, Lisbeth Bech, Anders Ohmann, Jens Breinholt, Claus Crone Fuglsang, Peter Rahbek Ostergaard
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Patent number: 7238378Abstract: The present invention relates to phytase variants derived from a parent phytase which is homologous to a Peniophora lycii phytase and comprises at least one substitution in at least one of a number of positions corresponding to a position in the Peniophora lycii phytase. The variants are of improved properties, in particular of a higher specific activity and/or more thermostable than the parent phytase, e.g. of a Tm of up to 82° C. at pH 5.5, as determined by DSC, and/or of a doubled specific activity. The invention also relates to DNA encoding the phytase variants, methods of their production, as well as the use thereof, e.g. in animal feed and animal feed additives.Type: GrantFiled: February 5, 2003Date of Patent: July 3, 2007Assignee: Novozymes A/SInventors: Tomoko Matsui, Claus Crone Fuglsang, Allan Svendsen, Shiro Fukuyama
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Patent number: 7226773Abstract: The present invention relates to enzyme preparations consisting essentially of an enzyme which has cellulytic activity and comprises a first amino acid sequence having the following sequence (SEQ ID NO: 79) Thr Arg Xaa Xaa Asp Cys Cys Xaa Xaa Xaa Cys Xaa Trp Xaa 1 2 3 4 5 6 7 8 9 10 11 12 13 14 and a second amino acid sequence having the following sequence Trp Cys Cys Xaa Cys (SEQ ID NO: 80) 1 2 3 4 5 wherein, at position 3 of the first sequence, the amino acid is Trp, Tyr or Phe; at position 4 of the first sequence, the amino acid is Trp, Tyr or Phe; at position 8 of the first sequence, the amino acid is Arg, Lys or His; at positions 9, 10, 12 and 14, respectively, of the first sequence, and at position 4 of the second sequence, the amino acid is any of the 20 naturally occurring amino acid residues with the provisos that, in the first amino acid sequence, (i) when the amino residue at position 12 is Ser, then the amino acid residue at positionType: GrantFiled: October 14, 2004Date of Patent: June 5, 2007Assignee: Novozymes A/SInventors: Martin Schulein, deceased, Torben Henriksen, legal representative, Lene Nonboe Andersen, Soren Flensted Lassen, Markus Sakari Kauppinen, Lene Lange, Ruby Ilum Nielsen, Shinobu Takagi, Michiko Ihara
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Patent number: 7220566Abstract: New subtilisin homologues (both nucleic acids and proteins) are provided. Compositions which include these new proteins, recombinant cells, shuffling methods involving the new homologues, antibodies to the new homologues, and methods of using the homologues are also provided.Type: GrantFiled: December 15, 2003Date of Patent: May 22, 2007Assignees: Novozymes A/s, Maxygen, Inc.Inventors: Jon E. Ness, Mark Welch, Lorraine J. Giver, Joel R. Cherry, Torben V. Borchert, Jeremy Minshull
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Patent number: 7217554Abstract: The present invention relates to isolated proteases of the RP-II type and variants of RP-II proteases exhibiting improved properties in comparison to the parent RP-II protease, DNA constructs and vectors coding for the expression of said proteases and variants, host cells capable of expressing the proteases and variants from the DNA constructs, as well as a method of producing them by cultivating said host cells. The proteases may advantageously be used as constituents in detergent compositions and additives, optionally in combination with other enzymes such as proteases, lipases, cellulases, amylases, peroxidases or oxidases.Type: GrantFiled: August 11, 2003Date of Patent: May 15, 2007Assignee: Novozymes A/SInventors: Mads Nørregaard-Madsen, Peter Rahbek Østergaard, Claus Bo Vøge Christensen, Søren Flensted Lassen
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Patent number: 7217433Abstract: The present invention relates to animal feed additives, which additives comprise a monocomponent xylanase derived from a strain of Byssochlamus, Chaetomium, Humicola, Malbranchea, Mucor, Myceliophthora, Paecilomyces, Talaromyces, Thermoascus, or Thielavia. In other aspects, the invention relates to monocomponent xylanase preparations, DNA constructs, recombinant expression vectors, host cells, and methods of producing monocomponent xylanase preparations.Type: GrantFiled: December 20, 1999Date of Patent: May 15, 2007Assignee: Novozymes A/SInventors: Peter Kamp Hansen, Peter Wagner, Anette Mullertz, Inge Helmer Knap
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Patent number: 7208310Abstract: The present invention relates to proteases of high specific activity homologous to proteases derived from Nocardiopsis, and the production thereof by the wild-type, and in recombinant host cells including transgenic plants and non-human transgenic animals. The proteases are effective in animal feed, and detergents. Characteristic structural features of relevance for the specific activity of these proteases of peptidase family S2A or S1E are disclosed.Type: GrantFiled: June 21, 2004Date of Patent: April 24, 2007Assignee: Novozymes A/SInventors: Soeren Flensted Lassen, Carsten Sjoholm, Peter Rahbek Ostergaard
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Patent number: 7189553Abstract: The present invention relates to enzymes produced by mutating the genes for a number of subtilisin proteases and expressing the mutated genes in suitable hosts are presented. The enzymes exhibit improved wash performance in comparison to their wild type parent enzymes. The enzymes are well-suited for use in detergent compositions.Type: GrantFiled: December 6, 2002Date of Patent: March 13, 2007Assignee: Novozymes A/SInventors: Dorrit Aaslyng, Sven Branner, Sven Hastrup, Leif Norskov-Lauritsen, Ole Hvilsted Olsen, Merete Simonsen, Eric Castelijn, Maarten Robert Egmond, Johan Haverkamp, John David Marugg, Arnoldus Theodorus Anthonius Mooren
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Patent number: 7183093Abstract: The present invention relates to mannanases comprising e.g., a sequence of amino acids 32–330 of SEQ ID NO: 2 or their homologues may be derived from e.g., Bacillus sp. I633, or may be encoded by polynucleotide molecules comprising a sequence of nucleotides 94–990 of SEQ ID NO: 1 from, polynucleotide molecules that encode a polypeptide that is at least 65% identical to the sequence of amino acids 32–330 of SEQ ID NO: 2, or degenerate nucleotide sequences thereof. The mannanases are alkaline and are useful e.g. in cleaning compositions, in a fracturing fluid useful to fracture a subterranean formation, for modifying plant material, and for treatment of cellulosic fibers.Type: GrantFiled: February 20, 2003Date of Patent: February 27, 2007Assignee: Novozymes A/SInventors: Markus Sakari Kauppinen, Martin Schulein, Kirk Schnorr, Lene Nonboe Andersen, Mads Eskelund Bjornvad
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Patent number: 7179630Abstract: The present invention relates to thermostable proteases having an amino acid sequence which homologous to the amino acid sequence of proteases derived from Nocardiopsis, and the production thereof by wild-type and recombinant host cells including transgenic plants and non-human transgenic animals. The proteases are effective in animal feed, in particular fish feed, and detergents. The proteases are capable of degrading the soybean Bowman-Birk inhibitor, and other antinutritional factors such as soybean agglutinin and the Kunitz trypsin inhibitor, as well as the isolated soy storage proteins glycinin and beta-conglycinin. Characteristic structural features of relevance for the thermostability of these proteases of peptidase family S2A or S1E are disclosed.Type: GrantFiled: June 21, 2004Date of Patent: February 20, 2007Assignee: Novozymes A/SInventors: Soeren Flensted Lassen, Carsten Sjoeholm, Peter Rahbek Oestergaard, Carsten Andersen, Morten Fischer
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Patent number: 7172997Abstract: The present invention relates to lipolytic enzyme variants with improved thermostability are obtained by substituting certain specified amino acid residues in a fungal lipolytic enzyme. The thermostable lipolytic enzyme variants are useful, e.g., for controlling pitch troubles in a process for the production of mechanical pulp or a paper-making process using mechanical pulp.Type: GrantFiled: June 15, 2006Date of Patent: February 6, 2007Assignee: Novozymes A/SInventors: Stefan Minning, Jesper Vind, Sanne O. Schroder Glad, Steffen Danielsen, Kim Borch