Patents Represented by Attorney Gerald D. Sharkin
  • Patent number: 5076501
    Abstract: A shotcrete gun having a rotatable multichamber rotor, with a top feed hopper for receiving a dry concrete mixture in a chamber, and a bottom outlet pipe for discharging the dry concret mixture from the chamber. The outlet pipe having a compressed air connector for connection to a compressed air source. The upper surface of the drum rotor adjoins a gasket having one or more openings fixed to a clamping plate. The lower surface of the drum rotor adjoins a gasket which is fixed to a base plate. The hopper and the outlet pipe being spaced such that a chamber which communicates directly with the hopper can be moved so that it no longer communicates with the hopper but communicates with the outlet pipe. The clamping plate has a compressed air connector for blowing the dry mixture out into the outlet pipe, and at least three pressure cylinders in order to press the gasket against the drum rotor. Means are provided for maintaining the pressure in the cylinders proportional to the pressure in the outlet pipe.
    Type: Grant
    Filed: April 6, 1990
    Date of Patent: December 31, 1991
    Assignee: Sandoz Ltd.
    Inventor: Otto Tschumi
  • Patent number: 5075318
    Abstract: 8.alpha.-Acylaminoergoline useful in the treatment of psychotic disorders and Parkinson's disease.
    Type: Grant
    Filed: November 2, 1990
    Date of Patent: December 24, 1991
    Assignee: Sandoz Ltd.
    Inventor: Walter Haefliger, deceased
  • Patent number: 5071439
    Abstract: A process for bleaching a textile substrate in an aqueous medium, comprisinga) applying a peroxide or a peroxide releasing product to the substrate (hereinafter defined as "component a"); andb) destroying excess component a) with a catalase.
    Type: Grant
    Filed: February 23, 1989
    Date of Patent: December 10, 1991
    Assignee: Sandoz Ltd.
    Inventor: Karl-Heinz Weible
  • Patent number: 5071871
    Abstract: New benz[b]pyranes and pyranopyridines of formula I, ##STR1## wherein the significances of substituents V, T, W, R.sub.3 to R.sub.5, R.sub.9, R.sub.10, m, X, Y and Z are given in claim 1 and their N-oxides and their salts and their use in the treatment of raised blood pressure in the treatment of vascular disorders and other disorders in which a reduction in tension of the smooth muscles is therapeutically useful, as well as in the treatment of hair loss and baldness. Further the compounds are useful in the treatment of asthma and obstructive disorders of the respiratory system as well as in the prophylactic treatment of obstructive or inflammatory airways disease, for example asthma, as well as novel pharmaceutical compositions comprising said K.sup.+ channel activators suitable for such use.
    Type: Grant
    Filed: July 10, 1990
    Date of Patent: December 10, 1991
    Assignee: Sandoz Ltd.
    Inventors: Stefan Blarer, John Morley, Ian D. Chapman
  • Patent number: 5069911
    Abstract: A controlled release formulation for oral administration comprisinga 9,10-dihydro ergot alkaloid,a pharmaceutically acceptable hydrophilic swelling substance anda pharmaceutically acceptable inert fatty material.
    Type: Grant
    Filed: June 22, 1990
    Date of Patent: December 3, 1991
    Assignee: Sandoz Ltd.
    Inventor: Othmar Zuger
  • Patent number: 5069822
    Abstract: A protective coating for application to steel reinforced concrete structures, comprising a liquid composition of elastomeric polymeric material having electrically conductive particulate matter evenly dispersed therein. A cathodic protection system embodying the coating comprises a moisture impervious membrane of elastomeric polymeric material having electrically conductive particulate material evenly dispersed therein, an electrically conductive grid embedded in the membrane or contiguous thereto, and direct current means connecting the grid electrically with the reinforcing bars.
    Type: Grant
    Filed: April 10, 1989
    Date of Patent: December 3, 1991
    Inventors: Thomas M. Callaghan, Vallabhdas M. Pasta, Vasant D. Kale, Charles A. Bruce
  • Patent number: 5066643
    Abstract: A peptide optionally in isosteric form wherein a methylene group in the backbone chain is disubstituted, one or both substituents being fluorine and/or chlorine, in free form or in pharmaceutically acceptable salt form, such as a compound of formula I ##STR1## wherein the substituents have various significances, or an isosteric form thereof,is useful as an enzyme inhibitor. In particular, as a renin inhibitor, it is useful in the prophylaxis or treatment of hypertension and congestive heart failure.It is prepared by a process comprising the step of coupling two corresponding peptide residues optionally in isosteric form, or precursors thereof, and if required appropriately converting any resultant compound in precursor form.
    Type: Grant
    Filed: January 18, 1990
    Date of Patent: November 19, 1991
    Assignee: Sandoz Ltd.
    Inventors: Robert H. Abeles, Michael H. Gelb
  • Patent number: 5066798
    Abstract: The invention provides crystallilne (6R, 7R)-7-[[2 ( 2-Amino-4-thiazolyl)-(Z)-2-(1-diphenylmethoxycarbonyl-1-methylethoxy)imino ]acetamido]-3-(1--pyridiniummethyl)-3-cephem-4-carboxylate and a process for its production.
    Type: Grant
    Filed: June 15, 1990
    Date of Patent: November 19, 1991
    Assignee: Biochemie Gesellschaft m.b.H.
    Inventor: Bernhard C. Prager
  • Patent number: 5064816
    Abstract: invention relates to heterocyclic phospholipids of formula III which are useful in treating multiple sclerosis:where R .sub.2 is n-C.sub.14 -C.sub.20 alkyl;each R.sub.1, independently, is methyl or ethyl; Y is --O-- or --S--;n is an integer 2 to 6.
    Type: Grant
    Filed: June 5, 1990
    Date of Patent: November 12, 1991
    Assignee: Sandoz Ltd.
    Inventor: William J. Houlihan
  • Patent number: 5059683
    Abstract: Compounds of the formula ##STR1## and acid addition salts thereof whereinA.sub.1 is C.sub.1-8 alkylene; C.sub.2-8 alkylene substituted by 1 or 2 substituents selected from hydroxy, halo and cyano; C.sub.2-8 alkenylene; cyclohexylene; cyclohexylene substituted by 1 to 3 C.sub.1-4 alkyl groups; phenylene or phenylene substituted by 1 or 2 substituents selected from halo, C.sub.1-4 alkyl and C.sub.1-4 alkoxy,B.sub.1 is ##STR2## wherein the quaternized nitrogen atom is bound to a carbon atom of A.sub.1,R is hydrogen, C.sub.1-4 alkyl, C.sub.5-6 cycloalkyl, phenyl, benzyl or phenylethyl,T is hydrogen, cyano, --COOR.sub.1, --CON(R.sub.2).sub.2, --SO.sub.2 N(R.sub.2).sub.2, ##STR3## wherein R.sub.1 is C.sub.1-6 alkyl or phenyl(C.sub.1-3 alkyl),each R.sub.3 is independently hydrogen, C.sub.1-4 alkyl, --CON(R.sub.2).sub.2 or --N(R.sub.5).sub.2, andX.sub.1 is --S--, --O-- or --N(R.sub.5)--,Y is hydrogen or a chromophoric group, andZ is ##STR4## wherein R.sub.11 is ##STR5## wherein W is --NR.sub.6 R.sub.7 or --.sup..sym.
    Type: Grant
    Filed: May 5, 1989
    Date of Patent: October 22, 1991
    Assignee: Sandoz Ltd.
    Inventors: Helmut A. Moser, Roland Wald
  • Patent number: 5047064
    Abstract: A method is provided for improving the dyeability and other properties of cellulosic materials, especially knitted cotton goods, wherein the material is impregnated with an aqueous liquor containing an effective amount of potassium hydroxide and preferably also an alkali metal silicate, a wetting agent and a sequestering agent, at a temperature of at least about 7.degree. C. (45.degree. F.). The application of tension is not necessary and the treatment is particularly useful for tubular knitted goods.
    Type: Grant
    Filed: August 14, 1989
    Date of Patent: September 10, 1991
    Assignee: Sandoz Ltd.
    Inventor: Angelo Rizzardi
  • Patent number: 5045083
    Abstract: The present invention relates to a process for dyeing polyamide comprisinga) one or more oxanilide U.V. absorbers (hereinafter defined as component a);b) one or more copper complexes, (hereinafter defined as component b); andc) one or more metal-free or metallized acid dyes in particular 1:2 metal complex dyes (hereinafter defined as component c) optionally together with one or more dyeing assistants.
    Type: Grant
    Filed: February 22, 1990
    Date of Patent: September 3, 1991
    Assignee: Sandoz Ltd.
    Inventor: Brian Bennett
  • Patent number: 5045537
    Abstract: Hydrophilic renin inhibitors, especially of formula ##STR1## wherein R.sub.1, W, o, m, n, A, B, C and D possess the definitions given in claim 2, processes for their production and their use in the treatment of hypertension, cardiac insufficiency and the treatment of diseases caused by retroviruses.
    Type: Grant
    Filed: September 14, 1988
    Date of Patent: September 3, 1991
    Assignee: Sandoz Ltd.
    Inventor: Beat Weidmann
  • Patent number: 5039680
    Abstract: The invention provides use of a 5HT-3 antagonist in the manufacture of a medicament suitable for the prevention or reduction of dependence on a dependence-inducing agent.
    Type: Grant
    Filed: January 19, 1990
    Date of Patent: August 13, 1991
    Assignee: Sandoz Ltd.
    Inventors: Assunta Imperato, Dietmar Romer
  • Patent number: 5039416
    Abstract: The invention relates to a process for treating industrial waste water which comprises either: (a) pre-treating the waste water with at least two different pre-treatments selected from adsorption, membrane filtration and oxidation and then, biologically purifying the waste water or, (b) neutralizing and biologically purifying the waste water and then after-treating the waste water either by membrane filtration in combination with adsorption or oxidation or, by oxidation optionally in combination with adsorption or filtration on a nanofiltration membrane or, by filtration on a nanofiltration membrane.
    Type: Grant
    Filed: May 3, 1989
    Date of Patent: August 13, 1991
    Assignee: Sandoz Ltd.
    Inventors: Richard Loew, Wolfgang Samhaber, Anton Wyss
  • Patent number: 5037448
    Abstract: Salts of ionic dyes with compounds which contain at least one ammonium, cycloammonium or immonium group and at least one aliphatic, cycloaliphatic or carbonyl radical-substituted aromatic group or containing a piperazine or piperidine group or a heteroaromatic group selected from those of the triazine, pyrimidine, quinazoline, quinoxaline, phthalazine or phthalimidine series or which contain at least two carboxylic acid groups, at least one amino groups and at least one carboxylic acid group or at least one sulfonic acid group and one aliphatic, cycloaliphatic, monocyclic aromatic or heteroaromatic group are useful for dyeing synthetic materials, particularly synthetic polyamides in the mass. The obtained dyeings have exceptionally good wet fastness.
    Type: Grant
    Filed: June 30, 1989
    Date of Patent: August 6, 1991
    Assignee: Sandoz Ltd.
    Inventor: Bansi L. Kaul
  • Patent number: 5037988
    Abstract: The invention relates to activated aminothiazolyl-oximinoacetic acid derivatives, their production and their use in the production of e.g. amides, in particular cephalosporin antibiotics.
    Type: Grant
    Filed: June 19, 1989
    Date of Patent: August 6, 1991
    Assignee: Gema S.A.
    Inventors: Jose Diago Meseguer, Asuncion Esteve Bianchini, Carlos E. Lenhardt Padro, Esteve Sans Pitarch
  • Patent number: 5037964
    Abstract: (i) Metal-free compounds of the formula ##STR1## These compounds are useful as dyes for paper and textiles.
    Type: Grant
    Filed: October 17, 1986
    Date of Patent: August 6, 1991
    Assignee: Sandoz Ltd.
    Inventors: Helmut A. Moser, Roland Wald
  • Patent number: 5035738
    Abstract: Aminopropylmorphine reduces the volatility of biologically active compounds containing a carboxylic acid group, including herbicides, fungicides and insecticides. Preferred herbicidal formulations, include benzoic acid compounds, phenoxy carboxylic acid compounds, glyphosate and mixtures thereof, especially dicamba and 2,4-D.
    Type: Grant
    Filed: December 23, 1988
    Date of Patent: July 30, 1991
    Assignee: Sandoz Ltd.
    Inventors: Johnny L. Burns, Richard Wilson
  • Patent number: 5034949
    Abstract: Single domain crack-free and striation-free KNbO.sub.3 crystals having a maximum iron content of 15 ppm, a process for the synthesis of such crystals and laser systems comprising single domain crack-free and striation-free KNbO.sub.3 crystals which systems convert green light of wavelength 500-540 nm into blue light of wavelength 430-470 nm.
    Type: Grant
    Filed: November 3, 1989
    Date of Patent: July 23, 1991
    Assignee: Sandoz Ltd.
    Inventor: Peter Gunter