Abstract: The use of liposomal formulations, particularly formulations of positively charged and neutral lipids facilitates cellular uptake of SDI molecules. The transcription and/or expression of SDI-1-encoding nucleic acid molecules is facilitated by constructs that contain intervening untranslated regions.
Type:
Grant
Filed:
October 24, 1994
Date of Patent:
April 16, 2002
Assignee:
Baylor College of Medicine
Inventors:
James R. Smith, David J. Drutz, Deborah R. Wilson, Louis A. Zumstein