Abstract: This invention relates to aqueous solutions containing Ni cation and hypophosphite anion which have a Ni cation concentration greater than 36 grams/liter. Such solutions have utility in electroless nickel plating baths and processes as make-up solutions and replenishing solutions. The increased concentration of Ni cation results from the addition of the nickel salt of an alkyl sulfonic acid to the solution.
Abstract: A process is disclosed for the eradication of and subsequent inhibition of bivalve mollusk settlement on solid surfaces immersed in water inhabited by said mollusk comprising introducing into said water, a specified tertiary amine salt at a rate and for a time at least sufficient to inhibit settlement of said mollusk.
Abstract: The inventors disclose a process for producing semi-bright to bright electrogalvanic coatings at high current densities, comprising electroplating a cathodic conductive substrate in a coating bath based on:a) a zinc sulfur-acid salt;b) a low molecular weight polyoxyalkylene glycol based on 2 to about 4 carbon atom alkylene oxides;c) an aromatic sulfonate; andd) a conductivity enhancing salt.The process includes maintaining the coating composition at a pH from about 2 to about 5 and the current density on the substrate at from about 1,000 to about 3,700 ASF. The zinc sulfur-acid salt includes zinc sulfate or a zinc organosulfonate, and the conductivity enhancing salt, a potassium salt. In one embodiment, the aromatic sulfonate comprises a condensation product of an aromatic sulfonate and formaldehyde. The inventors also describes coating bath compositions.
Abstract: A process is disclosed for the preparation of primary mercaptans by reacting hydrogen sulfide with an alpha-olefin in the presence of a reaction initiating amount of a borane represented by the formula R.sub.2 BH or R.sub.3 B where R is a linear or cyclic aliphatic or aryl group.
Type:
Grant
Filed:
April 10, 1996
Date of Patent:
April 21, 1998
Inventors:
Stanley R. Sandler, Pamela J. Peerce-Landers, Christian Forquy
Abstract: There is disclosed an isolated polypeptide and derivatives thereof having protease biological activity for human precursor IL-1.beta. and for a substrate comprising:R.sub.1 - Asp - R .sub.2 - R.sub.3wherein R.sub.1 and R.sub.3 are independently any D or L isomer amino acid, R.sub.2 is Ala or Gly, and wherein the specific protease cleavage site is between Asp and R.sub.2. Inhibitor compounds, compositions and methods for inhibiting Interleukin 1.beta. protease activity are also disclosed. The inhibitor compounds comprise an amino acid sequence of from 1 to about 5 amino acids having an N-terminal blocking group and a C-terminal Asp residue connected to an electronegative leaving group, wherein the amino acid sequence corresponds to the sequence Ala-Tyr-Val-His-Asp.
Type:
Grant
Filed:
February 28, 1994
Date of Patent:
May 16, 1995
Assignee:
Sterling Winthrop Inc.
Inventors:
Roy A. Black, Paul R. Sleath, Shirley R. Kronheim
Abstract: A hypodermic syringe holder adapted to receive a disposable ampoule and eject it in an axial direction. The holder comprises a plunger element, an optional camming element, a disposable hollow semi-cylindrical frame and a forwardly pivotable element.
Type:
Grant
Filed:
March 10, 1994
Date of Patent:
November 29, 1994
Assignee:
Sterling Winthrop Inc.
Inventors:
Roger G. Covington, Karen A. Malburne, Douglas C. Mehl, John Niedospial
Abstract: New fragments of the Factor VIII procoagulant protein (Factor VIIIC) are disclosed. These fragments have an Mr value of 88,000 d or 49,000 d or extend from amino acid residues 1974 to 2332 or 2052 to 2332. These fragments have use in the treatment of patients who have developed antibodies which inhibit Factor VIII.
Type:
Grant
Filed:
April 6, 1987
Date of Patent:
December 25, 1990
Assignees:
Scripps Clinic and Research Foundation, Rorer Biotechnology Inc.
Inventors:
Dorothea H. Scandella, William N. Drohan, Theodore S. Zimmerman, Carol A. Fulcher
Abstract: A recombinant DNA expression vector comprising an Epstein-Barr virus origin of replication, an EBNA-1 gene, a selectable marker expression cassette and a human gamma interferon expression cassette comprising a promoter region, an open reading frame encoding human gamma interferon and a polyadenylation region; a mammalian host cell transformed by said vector; and a process for producing human gamma interferon using said transformed mammalian host cell.
Type:
Grant
Filed:
February 18, 1987
Date of Patent:
July 3, 1990
Assignee:
Meloy Laboratories Inc.
Inventors:
Janet M. Young, Nava Sarver, William N. Drohan
Abstract: This invention relates to chemical compounds which possess valuable therapeutic activity particularly as lipoxygenase and phospholipase C inhibitors and as platelet-activating factor receptor antagonists. The compounds posses anti-inflammatory anti-asthmatic and anti-allergic properties and are additionally useful for the treatment of myocardial infarctions.
Abstract: An improved metal-air button cell is provided. The cell is comprised of the following components: a conductive metal can, a cathode assembly in the can, a conductive metal cover, and a separator between the cathode assembly, wherein the metal cover and separator provide borders of a space in which an anode material can be placed. The improvement is that the amount of anode material is not sufficient to fill the space provided for it, and, wherein, the anode material is positioned against the separator and a void exists between the cover and the anode material.
Abstract: Iminobenzyl dihydropyridines of the formula ##STR1## wherein, each R is alkyl, alkenyl, alkynyl, cycloalkyl, aryl, aralkyl, sulfonamido, halogen, alkoxy, alkenyloxy, alkynyloxy, cyano, hydroxy, acyloxy, nitro, amino, alkylmercapto, alkylamino, alkanoylamino, carbalkoxyamino, carboxy, methanesulfonyl, carbalkoxy or trifluoromethyl;each R.sub.4 is lower alkoxy;each R.sub.2 is lower alkyl;and R.sub.3 is alkyl, alkenyl, alkynyl, cycloalkyl, heterocyclic or ##STR2## wherein R is as previously defined; have anti-hypertensive activity.
Abstract: Migration of suspended materials in nail enamels is prevented by the addition thereto of from about 0.10 to 5.0% by weight of a phosphatide such as lecithin. Settling and migration of suspended materials in nail enamels is prevented by the addition thereto of from 0.10 to 5.0% by weight of a phosphatide such as lecithin and from about 0.04 to 0.20% by weight of a cosmetically acceptable acid.
Type:
Grant
Filed:
December 18, 1980
Date of Patent:
November 24, 1981
Assignee:
USV Pharmaceutical Corporation
Inventors:
Robert Socci, Anthony Gunderman, Eustace Fotiu, Bernard Kabacoff
Abstract: A material useful as a separator in batteries and a process for making the material is provided. This material is a polyolefin having grafted to it side chains derived from an ethylenically unsaturated ionogenic monomer and cross-linked with sulfur.
Type:
Grant
Filed:
July 17, 1978
Date of Patent:
March 3, 1981
Assignee:
ESB Inc.
Inventors:
Philip Bernstein, James P. Coffey, Alan E. Varker
Abstract: A lead acid battery plate is disclosed wherein sodium silicate is added to the paste mix before the grids are pasted to reduce the tendency to create lead dust from handling of the plates without significantly reducing battery performance.
Type:
Grant
Filed:
October 16, 1978
Date of Patent:
April 8, 1980
Assignee:
ESB Technology Company
Inventors:
Stanley M. Davis, Ralph E. Thomas, Philip Bernstein
Abstract: A disc formed of a resilient plastic exhibiting a low creep characteristic and having a pressure vent is used to close the mouth of a tubular cell envelope of a primary cell. An elongated terminal is inserted through the disc and into the cell interior. The pressure vent is in the disc at a location between the terminal and the edge of the disc. The vent comprises a recess having a frangible diaphragm with at least one groove. At a predetermined pressure the diaphragm breaks at the groove, releasing pressure.
Abstract: An improved high drain rate lithium cell is provided. The improvement is the use of an additive to stabilize the cell. The additive is a minor porton of a tetra alkyl onium salt.
Abstract: A polarity indicating system using a light emitting diode is mounted on the clip for a battery charger to provide an indication that the battery charger is properly connected to the battery being charged. In the preferred embodiment, the LED is connected to a test probe mounted in one of the handles of the negative clip and connected in series between the test probe and the positive cable. An alternate embodiment uses the polarity indicating system on battery booster cables.
Abstract: A process for preparing a polymeric material grafted throughout its bulk is provided. A polymer having finely divided particles is blended with silica and maintained in a fluidized bed. The polymer is activated by passing ozone uniformly through the blend to initiate incipient labile sites in the molecular structure of the polymer. The polymer is then reacted with an ethylenically unsaturated ionogenic monomer to graft polymerize the monomer onto the polymer. The grafted polymer may then be converted to a salt form by reacting with alkaline compounds. The resultant powders can be fused into any desired shape by conventional polymer plastic processes.
Type:
Grant
Filed:
March 23, 1977
Date of Patent:
December 26, 1978
Assignee:
ESB Incorporated
Inventors:
Philip Bernstein, James P. Coffey, Alan E. Varker
Abstract: A process for improving leakage resistant in a galvanic cell is provided. This is done by making an improved grommet and metal cover. The process comprises swelling a grommet which has been placed tightly around the periphery of a metal cover until the grommet is loose upon the metal cover, forcing a sealant solution between the swollen grommet and metal cover and then shrinking the grommet to substantially its original size to trap the sealant compound between the grommet and metal cover.