Patents Represented by Law Firm Hammond & Littell, Weissenberger & Muserlian
  • Patent number: 4412988
    Abstract: Novel hexapeptides of the formulaCys--X--Y--D--Lys--Z Iwherein X is a sequence selected from the group consisting of Ala--Ala and Glu--His, Y is selected from the group consisting of Cys and Phe and Z is Phe when Y is Cys or Z is Cys when Y is Phe, the two Cys groups in the molecule being joined by a disulfide bridge, and their functional derivatives such as their non-toxic, pharmaceutically acceptable acid addition salts, salts with bases, esters and amides and metallic complexes thereof having an influence on the memory process and their preparation.
    Type: Grant
    Filed: October 9, 1981
    Date of Patent: November 1, 1983
    Assignee: Roussel Uclaf
    Inventors: Jean-Claude Gasc, Serge Geoffre, Michel Hospital, Jacques Laurent
  • Patent number: 4413060
    Abstract: A process and apparatus for the distribution and preparation of samples from primary vessels, especially samples of patients' sera, liquid reagents or the like, which are transferred into fixedly mounted secondary vessels of any desired construction, preferably in accordance with the data from a distribution sheet recorded by a control programing apparatus, where the secondary vessels can be moved into position one after the other by means of a transporting carriage for the primary vessel having an associated diluter, this transporting carriage being movable in the x-y plane by means of two stepping motors, and the primary vessel is brought back into its starting position after each delivery or after delivery of the samples intended for the entire series of samples.
    Type: Grant
    Filed: September 10, 1981
    Date of Patent: November 1, 1983
    Assignee: Boehringer Ingelheim Zentrale GmbH
    Inventors: Gerd Assmann, Horst-Dietrich Helb
  • Patent number: 4412946
    Abstract: Novel water-soluble, immunostimulating glycoproteins extracted from Klebsiella pneumoniae containing 30 to 45% by weight of proteins, 30 to 40% by weight of neutral saccharides, up to 4% by weight of glucuronic acid, 2 to 5% by weight of osamines and having a molecular weight of about 350,000 daltons.
    Type: Grant
    Filed: September 10, 1981
    Date of Patent: November 1, 1983
    Assignee: Roussel Uclaf
    Inventors: Rene Zalisz, Marie-France Salles
  • Patent number: 4411955
    Abstract: A reactive hardenable binder composition based on(A) at least one aliphatic, cycloaliphatic or aliphatic-cycloaliphatic polyepoxide wherein at least 2 epoxidized cycloaliphatic radicals are bound via an aliphatic bridge,(B) at least one polycarboxylic acid unit of formula ##STR1## having an acid number between 30 and 400 whereinR.sup.1 is a radical of an at least oligomer product selected from the group consisting of polyesters and polymers having initially free OH-groups,R.sup.2 is a radical of a dicarboxylic carbocyclic acid having a COOH-group in ortho-position to its ester bond and(C) a catalyst component of the formula ##STR2## wherein R.sup.
    Type: Grant
    Filed: November 2, 1981
    Date of Patent: October 25, 1983
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Josef Mondt, Gerd Walz, Thaddaus Wirth
  • Patent number: 4412069
    Abstract: A novel process for the preparation of a compound of the formula ##STR1## wherein X is selected from the group consisting of oxygen and sulfur and n is 1,2 or 3 comprising reacting in an organic solvent in the presence of a strong base the lactone of cis 2,2-dimethyl-3S-(dihydroxymethyl)-cyclopropane-1R-carboxylic acid with a compound of the formula ##STR2## to obtain a compound of the formula ##STR3## reacting the latter with an acid agent in an apolar organic solvent to obtain a compound of the formula ##STR4## and reacting the latter with a basic agent in an apolar organic solvent to obtain a compound of formula I useful for the preparation of insecticidal esters and the novel compounds of formula I wherein n is 1 or 3.
    Type: Grant
    Filed: July 17, 1979
    Date of Patent: October 25, 1983
    Assignee: Roussel Uclaf
    Inventors: Jacques Martel, Jean Tessier, Jean-Pierre Demoute
  • Patent number: 4410721
    Abstract: A novel cyclopropene-carboxylate of the formula ##STR1## wherein R is alkyl of 1 to 6 carbon atoms and their preparation and a process using the compounds of formula I to obtain cis compounds of the formula ##STR2##
    Type: Grant
    Filed: July 16, 1981
    Date of Patent: October 18, 1983
    Assignee: Roussel Uclaf
    Inventors: Michel Franck-Neumann, Michel Miesch
  • Patent number: 4410527
    Abstract: Compounds of the formula ##STR1## wherein R is 1-methyl-4-piperididinyl, 4-methyl-1-piperazinyl, or 3 - or 3 -tropanyl, each of which may optionally have another methyl substituent attached to the heterocyclic ring;R.sub.1 is hydrogen or alkyl of 1 to 4 carbon atoms;R.sub.2 is hydrogen, halogen or alkyl of 1 to 4 carbon atoms; andX is oxygen, --NH-- or --N(CH.sub.3)--;and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as anti-ulcerogenics.
    Type: Grant
    Filed: January 31, 1983
    Date of Patent: October 18, 1983
    Assignee: Dr. Karl Thomae Gesellschaft mit beschrankter Haftung
    Inventors: Wolfhard Engel, Gunther Schmidt, Wolfgang Eberlein, Gunter Trummlitz, Rudolf Hammer, Piero Del Soldato
  • Patent number: 4408593
    Abstract: This invention relates to a liquid fuel combustion apparatus such as oil space heater in which liquid fuel is vaporized by a vaporizer and the vaporized liquid fuel is injected through a first nozzle to a burner. The vaporizer is heated by combustion of fuel gas which is injected through a second nozzle to the burner before the vaporizer has been heated up to a temperature at which the liquid fuel passing the vaporizer is evaporated. The injection of the fuel gas from the second nozzle to the burner is changed to the injection of the vaporized liquid fuel from the first nozzle when the vaporizer has been heated up to a desired temperature. The supply of the liquid fuel to the vaporizer is carried out by a fuel pump which is driven by electric power generated by a thermopile.
    Type: Grant
    Filed: May 27, 1982
    Date of Patent: October 11, 1983
    Assignee: Nippon Carbureter Co., Ltd.
    Inventors: Michitake Furumoto, Shinichi Harada
  • Patent number: 4409373
    Abstract: This invention relates to adhesive composition. More particularly, this invention relates to adhesive compositions comprising polyamide (I) prepared by condensing dimeric higher fatty acids and monomeric fatty acids with polyether diamines and aliphatic or cycloaliphatic diamines and polyamide (II) prepared by condensing dimeric higher fatty acids and monomeric fatty acids with aliphatic or cycloaliphatic polyamines.
    Type: Grant
    Filed: March 17, 1982
    Date of Patent: October 11, 1983
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Norbert Wiemers, Italo Albini
  • Patent number: 4409235
    Abstract: Compounds of the formula ##STR1## wherein R is hydrogen or methyl, and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as bradycardiacs.
    Type: Grant
    Filed: August 2, 1982
    Date of Patent: October 11, 1983
    Assignee: C. H. Boehringer Sohn
    Inventors: Helmut Stahle, Herbert Koppe, Werner Kummer, Walter Kobinger, Christian Lillie, Ludwig Pichler
  • Patent number: 4409206
    Abstract: This invention is directed to a pharmaceutical preparation for transdermal application, which comprises a film comprising a skin-compatible polyacrylate, which swells in water and a pharmaceutically active substance in amorphous form.The invention is also directed to the preparation of said pharmaceutical preparation and its use in administering pharmaceutically active substances.
    Type: Grant
    Filed: August 14, 1981
    Date of Patent: October 11, 1983
    Assignee: Boehringer Ingelheim GmbH
    Inventor: Herbert Stricker
  • Patent number: 4409220
    Abstract: Compounds of the formula ##STR1## wherein A and B, which may be the same or different, each represent methylene, (alkyl of 1 to 3 carbon atoms)-methylene, ethylene or (alkyl of 1 to 3 carbon atoms)-ethylene;R.sub.1 is hydrogen, alkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 7 carbon atoms, alkenyl of 3 to 6 carbon atoms, phenyl-(alkyl of 1 to 3 carbon atoms), halophenyl-(alkyl of 1 to 3 carbon atoms), alkanoyl of 1 to 3 carbon atoms, phenyl-(alkanoyl of 1 to 3 carbon atoms), halophenyl-(alkanoyl of 1 to 3 carbon atoms), alkoxycarbonyl of 2 to 4 carbon atoms, aralkoxycarbonyl of 8 to 10 carbon atoms or phenyl;one of R.sub.2 and R.sub.3 is amino and the other is hydrogen, chlorine, bromine, alkyl of 1 to 3 carbon atoms, alkoxy of 1 to 3 carbon atoms, alkoxycarbonyl of 2 to 4 carbon atoms, phenyl or halophenyl;and non-toxic, pharmacologically acceptable acid addition salts thereof. The compounds as well as their salts are useful as bradycardiacs.
    Type: Grant
    Filed: August 27, 1981
    Date of Patent: October 11, 1983
    Assignee: Dr. Karl Thomae Gesellschaft mit beschrankter Haftung
    Inventors: Rudolf Hurnaus, Gerhart Griss, Robert Sauter, Wolfgang Grell, Walter Kobinger, Ludwig Pichler
  • Patent number: 4408066
    Abstract: Novel methyl esters of cis or trans configuration in their optically active form of the formual ##STR1## which are useful as intermediates for the preparation of pesticidal compounds and a process for their preparation and intermediates.
    Type: Grant
    Filed: October 2, 1981
    Date of Patent: October 4, 1983
    Assignee: Roussel Uclaf
    Inventor: Alain Krief
  • Patent number: 4407761
    Abstract: A process for the preparation of a .omega.-amino-1-hydroxyalkylidine-1,1-biphosphonic acid of the formula ##STR1## wherein n is an integer from 3 to 5, consisting essentially of the steps ofreacting an aminocarboxylic acid of the formulaNH.sub.2 --CH.sub.2 --(CH.sub.2).sub.m --COOHwherein m is an integer from 2 to 4, with a phosphonating reactant selected from the group consisting of(a) a mixture of phosphorous acid and PCl.sub.3,(b) a mixture of phosphorous acid and PCl.sub.5, and(c) a mixture of phosphorous acid and POCl.sub.3,hydrolyzing the reaction mixture with a strong acid which does not oxidize aminophosphonic acids, and recovering said .omega.-amino-1-hydroxyalkylidene-1,1-bisphosphonic acid.
    Type: Grant
    Filed: April 16, 1981
    Date of Patent: October 4, 1983
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Helmut Blum, Karl-Heinz Worms
  • Patent number: 4407160
    Abstract: Device for determining the quantity of the contents of a tank (1) mounted in a frame (3,4) which rests on a base with four points of support disposed in the corner points of a rectangle, two adjacent points of support being constituted by force measuring elements (6) each consisting of a generally block-shaped body (7) of metal, in which an opening (8) is cut out such that at the lower and upper sides of the body two relatively thin elongated and substantially horizontally extending portions (9,10) are formed which are connected to each other at both ends by thicker material portions disposed at the vertical sides of the body, whereas at the lower side of the body a foot (11) is formed which protrudes from one vertical side towards the vertical axis of the body, and with which the body rests on the base, and the supporting frame (3,4) of the tank is affixed on the upper side of the body near its other vertical side, and two strain gauges (T1,T2) aligned in spaced apart relation with each other in the directio
    Type: Grant
    Filed: April 3, 1981
    Date of Patent: October 4, 1983
    Assignee: Bavaria B.V.
    Inventor: Reindert van de Velde
  • Patent number: 4407947
    Abstract: A process for obtaining metal-free corrinoids consisting of inoculating a culture media free of added compounds of metals of the VIIIth group of the Periodic Table with a parent strain of Rhodopseudomonas, cultivating under illumination, repeating the steps of inoculating and cultivating employing said culture media and said illumination employing a part of the sequential culture from the preceding stage as an inoculum in each subsequent state, for a series of several pre-production culture stages, inoculating said culture media with the preceding sequential culture for the last time, cultivating under illumination, separating the microorganism from the culture media of the production culture stage and isolating metal-free corrinoids from the culture media of the production culture stage.
    Type: Grant
    Filed: September 14, 1981
    Date of Patent: October 4, 1983
    Assignee: Gesellschaft fur Biotechnologische Forschung mbH (GBF)
    Inventors: Volker Koppenhagen, Gerhard Schlingmann, Bernd Dresow, Ludwig Bischoff, Rosemarie Penkert, Eicke Siefert
  • Patent number: 4406829
    Abstract: Novel esters of all possible isomers and mixtures thereof of compounds of the formula ##STR1## wherein n is a number of 2,3 or 4 and R is selected from the group consisting of (a) alkyl of 1 to 12 carbon atoms optionally substituted with a member of the group consisting of cycloalkyl of 3 to 6 carbon atoms and a hydrocarbon chain of 2 to 8 carbon atoms optionally interrupted by an oxygen atom or a ketone group, (b) alkenyl and alkynyl of 3 to 8 carbon atoms, (c) cycloalkyl of 3 to 12 carbon atoms optionally containing at least one double bond and optionally substituted with at least one alkyl of 1 to 5 carbon atoms and (d) aralkyl of 7 to 12 carbon atoms optionally substituted with at least one member of the group consisting of alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms, halogen and --CF.sub.3 having perfume and insecticidal properties.
    Type: Grant
    Filed: November 5, 1981
    Date of Patent: September 27, 1983
    Assignee: Roussel Uclaf
    Inventors: Jacques Martel, Jean Buendia, Francois Nezot
  • Patent number: 4405605
    Abstract: This invention relates to fungicidal compositions comprising triforine and carbendazim as active ingredients, wherein the composition comprises carbendazim suspended in a solution of a triforine in dimethylformamide, N-methylpyrrolidone, or a mixture thereof and contains a stabilizer selected from the group consisting of saccharides, polyethylene glycol, polyvinylpyrrolidone/polyvinylacetate mixtures, and mixtures thereof.
    Type: Grant
    Filed: July 24, 1981
    Date of Patent: September 20, 1983
    Assignee: Celamerck GmbH & Co., KG
    Inventor: Hanshelmut Itzel
  • Patent number: RE31421
    Abstract: An improved building material element or board having good thermal insulation properties comprising expanded vermiculite granules coated with 2 to 30% by weight, based on the weight of vermiculite, with an organic binder formed into a press cake which is then press heated to form the building element, the improvement comprising that at least a portion of the coated vermiculite granules are recycled particles which increases the density and has a more uniform and more easily sized surface and a process for its preparation.
    Type: Grant
    Filed: September 8, 1981
    Date of Patent: October 18, 1983
    Assignee: Isovolta Osterreichische Isolierstoffwerke Aktiengesellschaft
    Inventors: Felix Wehrmann, Rene-Hagen Voelki, Edwin Wojta
  • Patent number: RE31425
    Abstract: A three-dimensional resealable container comprising a top portion, a bottom portion and at least one side portion, the top portion being comprised of an inner section with die-cut portion and an outer section provided with a hinged flap portion adapted to open and close the container with the die-cut portion secured to the hinged flap, which container is useful for dispensing particulate or powdered material.
    Type: Grant
    Filed: July 22, 1982
    Date of Patent: October 25, 1983
    Assignee: Church & Dwight Co., Inc.
    Inventors: John J. Steinke, George Kaufman