Patents Represented by Attorney Heller Ehrman White & McAuliffe
  • Patent number: 6870785
    Abstract: A nonvolatile ferroelectric memory device having a multi-bit control function can store and sense multi-bit data in a ferroelectric memory cell. In the memory device, a plurality of cell array blocks generates a plurality of different sensing critical voltages in a reference timing strobe interval. As a result, in different time intervals, the plurality of sensing critical voltages are compared with a plurality of cell data sensing voltages applied from a main bitline. A data register array unit stores a plurality of cell data applied from the plurality of cell array blocks in response to a plurality of read lock signals activated at different timings in different time intervals, respectively. Therefore, the plurality of data bits can be stored in a cell.
    Type: Grant
    Filed: December 22, 2003
    Date of Patent: March 22, 2005
    Assignee: Hynix Semiconductor Inc.
    Inventor: Hee Bok Kang
  • Patent number: 6870033
    Abstract: Humanized anti-IL-8 monoclonal antibodies and variants thereof are described for use in diagnostic applications and in the treatment of inflammatory disorders. Also described is a conjugate formed by an antibody fragment covalently attached to a non-proteinaceous polymer, wherein the apparent size of the conjugate is at least about 500 kD. The conjugate exhibits substantially improved half-life, mean residence time, and/or clearance rate in circulation as compared to the underivatized parental antibody fragment.
    Type: Grant
    Filed: February 20, 1998
    Date of Patent: March 22, 2005
    Assignee: Genentech, Inc.
    Inventors: Vanessa Hsei, Iphigenia Koumenis, Steven R. Leong, Leonard G. Presta, Zahra Shahrokh, Gerarado A. Zapata
  • Patent number: 6870034
    Abstract: A method for purifying proteins by Protein A chromatography is described which comprises removing contaminants by washing the solid phase with various intermediate wash buffers.
    Type: Grant
    Filed: February 3, 2003
    Date of Patent: March 22, 2005
    Assignee: Genentech, Inc.
    Inventors: Timothy N. Breece, Robert L. Fahrner, Jeffrey R. Gorrell, Kathlyn Pham Lazzareschi, Philip M. Lester, David Peng
  • Patent number: 6869539
    Abstract: Cost-effective processes and tools used therein are described that decontaminate sludge using remedial water in a closed and environmentally friendly system. Typical contaminants such as toxic metals, microorganisms, and toxic compounds are detoxified or destroyed by one or more remedial water treatments to sludge that is confined to the closed system. The closed system may comprise a covered rail road car, ISO container, or other large space into which the remedial water, and optionally, remedial gas, is applied by injection or other means. In a preferred embodiment, water is electrochemically activated at the site of use and injected through an array of pipes within the container. A large variety of other waters and combinations of water, and even air treatments are particularly useful in combination with the closed system for treating sludge.
    Type: Grant
    Filed: November 21, 2001
    Date of Patent: March 22, 2005
    Inventor: Richard G. Sheets
  • Patent number: 6867998
    Abstract: The present invention discloses a cell array block of a ferroelectric random access memory (FeRAM) and an FeRAM using the same. In the multi-bit line structure cell array block of the FeRAM having a sub bit line and a main bit line, and including a plurality of sub cell arrays for inducing a sensing voltage of the main bit line by converting a sensing voltage of the sub bit line into current, in order to overcome different data properties of the whole sub cell arrays due to delay time differences by positions of the sub cell arrays, a different size of sensing loads are selectively transmitted to the main bit line according to the positions of the operated sub cell arrays, or a different size of ferroelectric capacitors are used in a memory cell according to the positions of the sub cell arrays. As a result, the cell data properties of the whole cell array block are equalized for even distribution.
    Type: Grant
    Filed: December 18, 2003
    Date of Patent: March 15, 2005
    Assignee: Hynix Semiconductor Inc.
    Inventor: Hee Bok Kang
  • Patent number: 6865120
    Abstract: The present invention discloses a ferroelectric random access memory having a multi-bit line structure. The ferroelectric random access memory includes a plurality of cell array blocks for storing cell data, a common data bus unit for transmitting read/write data, and a timing data register array unit for sensing the read data and outputting the write data to the common data bus unit. The timing data register array unit senses the read data by using timing of a sensing voltage of the common data bus unit to reach the sensing threshold voltage. As a result, the ferroelectric random access memory improves a sensing margin in a low voltage and increases a sensing speed.
    Type: Grant
    Filed: December 8, 2003
    Date of Patent: March 8, 2005
    Assignee: Hynix Semiconductor Inc.
    Inventor: Hee Bok Kang
  • Patent number: 6864246
    Abstract: The invention concerns more particularly dodecylthio-phenylacetanilide derivative complexes such as (S)-2?,3?,5?-trimethyl-4?-hydroxy-?-dodecylthio-phenylacetanilide or related derivatives thereof and cyclodextrins.
    Type: Grant
    Filed: April 9, 2002
    Date of Patent: March 8, 2005
    Assignee: Pierre Fabre Medicament
    Inventors: Joël Bougáret, Elie Leverd, Marie-Dominique Ibarra, Alexandre Gil
  • Patent number: 6863782
    Abstract: Di(ketene acetals) are prepared by photoisomerizing the corresponding di(vinyl acetals).
    Type: Grant
    Filed: November 15, 2002
    Date of Patent: March 8, 2005
    Assignee: A.P. Pharma, Inc.
    Inventors: Peter W. Newsome, A. Roger Frisbee, Zinovy Itov, April J. Morgan, Robert A. Noe
  • Patent number: 6863826
    Abstract: Animal waste such as fecal material from swine, chicken, turkey, and cattle is converted into useful forms such as fertilizer, other types of soil builders, and even nutrient feed additives. Devices, systems, and methods are provided that allow economical conversion and in many instances, alleviate the production and release of undesirable gases such as sulfide and ammonia. In one embodiment, undesirable anaerobic and facultative anaerobic bacteria are killed at a greater rate than desirable soil compatible aerobic bacteria. The use of low temperature killing diminishes off gassing commonly associated with other techniques, and the use of gas trapping additives such as zeolites provides enhanced soil building qualities such as slow release of nitrogen and slow release of moisture to soil. The methods allow convenient adjustment of composition, allowing conversion of waste into tailored designer fertilizer suited for particular soils.
    Type: Grant
    Filed: November 25, 2003
    Date of Patent: March 8, 2005
    Inventor: Richard G. Sheets
  • Patent number: 6861068
    Abstract: A semi-solid delivery vehicle contains a polyorthoester and an excipient, and a semi-solid pharmaceutical composition contains an active agent and the delivery vehicle. The pharmaceutical composition may be a topical, syringable, or injectable formulation; and is suitable for local delivery of the active agent. Methods of treatment are also disclosed.
    Type: Grant
    Filed: January 26, 2004
    Date of Patent: March 1, 2005
    Assignee: A.P. Pharma, Inc.
    Inventors: Steven Y. Ng, Hui-Rong Shen, Jorge Heller
  • Patent number: 6862111
    Abstract: This invention relates to a color image dithering method and apparatus for producing an output point in an output color space corresponding to a selected vertex in a tetrahedron of a three-dimensional cubic subinterval of a pixel point in a source color space.
    Type: Grant
    Filed: January 31, 2001
    Date of Patent: March 1, 2005
    Assignee: PictoLogic, Inc.
    Inventors: Frederick Lin, Shultz Chan
  • Patent number: 6861244
    Abstract: The invention relates to nasal or oral administration of a compound containing inactivated influenza virus antigen and aluminum as adjuvant for the prophylaxis of influenza virus infections. Said vaccine is especially suitable for inducing a mucosal IgA immune response and systemic IgG immune response.
    Type: Grant
    Filed: August 13, 2003
    Date of Patent: March 1, 2005
    Assignee: Baxter Healthcare S.A.
    Inventors: Noel Barrett, Otfried Kistner, Marijan Gerencer, Friedrich Dorner
  • Patent number: 6862231
    Abstract: A repair circuit of a semiconductor memory device features a fuse box unit, a fuse stop unit and a repair control circuit unit. The fuse box unit outputs a first control signal to command a failed cell to be substituted with a spare cell when inputted address information is identical with address information programmed in a fuse. The fuse stop unit outputs a third control signal to command the spare cell to be substituted in response to the first control signal and a second control signal for representing if the spare cell is normal or not. The repair control circuit unit substitutes the failed cell with the spare cell in response to the third control signal. As a result, the repair circuit of the present invention substitutes a failed cell with a normal spare cell when a space cell is normal, without performing a repair operation when a spare cell fails.
    Type: Grant
    Filed: June 30, 2003
    Date of Patent: March 1, 2005
    Assignee: Hynix Semiconductor Inc.
    Inventor: Bon Seong Koo
  • Patent number: 6858864
    Abstract: A photonic device includes a silicon semiconductor based superlattice. The superlattice has a plurality of layers that form a plurality of repeating units. At least one of the layers in the repeating unit is an optically active layer with at least one species of rare earth ion.
    Type: Grant
    Filed: April 16, 2004
    Date of Patent: February 22, 2005
    Assignee: Translucent Photonics, Inc.
    Inventors: Petar B. Atanackovic, Larry R. Marshall
  • Patent number: 6858705
    Abstract: Methods are described for conjugating radioiodinated non-metabolizable peptides to proteins and antibodies with improved yields and qualities of conjugates. Radioiodinated residualizing antibody conjugates comprising any aminopolycarboxylate-appended peptide, or any carbohydrate-appended peptide, are also provided. Additionally, methods are described for conjugating radioiodinated aminopolycarboxylates to proteins and antibodies, as well as for conjugating radioiodinated non-metabolizable carbohydrates to proteins and antibodies by a variety of chemical approaches. The instant radioiodinated residualizing antibody conjugates are particularly stable in vivo and are suitable for radioimmunodetection and radioimmunotherapy.
    Type: Grant
    Filed: October 16, 2003
    Date of Patent: February 22, 2005
    Assignee: Immunomedics, Inc.
    Inventors: Serengulam V. Govindan, Gary L. Griffiths
  • Patent number: 6858544
    Abstract: A method for forming a bit line of a semiconductor device wherein a first opening in an interlayer insulation film is formed in a P+ S/D (source/drain) region, a post etch treatment (PET) for stabilizing the resistance in the P+ S/D opening is performed, followed by the subsequent formation of a second opening in the N+ S/D region, such that any increase of the resistance of the N+ S/D opening by the PET is thereby prevented.
    Type: Grant
    Filed: June 30, 2003
    Date of Patent: February 22, 2005
    Assignee: Hynix Semiconductor Inc.
    Inventors: Sung Gon Jin, Jai Sun Roh
  • Patent number: 6855661
    Abstract: This invention provides a new catalyst for purification of diesel engine exhaust gas comprising a carrier of at least one sulfur-resistant refractory oxide and at least one catalytic metal, wherein at least one solid acid and/or sulfuric acid is carried on the carrier by adding at least one precursor of said solid acid and/or sulfuric acid during the preparation of the carrier, and preparation thereof. The catalyst of this invention is thermally and chemically durable and can effectively remove particulate matters, hydrocarbons and nitrogen oxides contained in the diesel engine exhaust gas at low temperatures.
    Type: Grant
    Filed: May 22, 2001
    Date of Patent: February 15, 2005
    Assignee: KH Chemicals Co., LTD
    Inventor: Young-Nam Kim
  • Patent number: 6852849
    Abstract: Non-oligomerizing fluorescent proteins, which are formed by operatively linking two or more monomers of a fluorescent protein, or which are derived from a fluorescent protein having at least one mutation that reduces or eliminates the ability of the fluorescent protein to oligomerize, are provided. The non-oligomerizing fluorescent proteins can be derived from a naturally occurring green fluorescent protein, a red fluorescent protein, or other fluorescent protein, or a fluorescent protein related thereto. Also provided is a fusion protein, which includes a non-oligomerizing fluorescent protein linked to at least one polypeptide of interest. In addition, a polynucleotide encoding a non-oligomerizing fluorescent protein is provided, as is a recombinant nucleic acid molecule, which includes polynucleotide encoding a non-oligomerizing fluorescent protein operatively linked to at least a second polynucleotide.
    Type: Grant
    Filed: May 24, 2001
    Date of Patent: February 8, 2005
    Assignee: The Regents of the University of California
    Inventors: Roger Y. Tsien, Robert E. Campbell
  • Patent number: 6853655
    Abstract: A laser system includes a pump source that produces a first output. The pump source has a feedback loop with a first summing junction and a first command that has step quantization or digitized set point. An output device is coupled to the pump source to receive the first output and produce a second output. A feedback loop is coupled to the first summing junction. The feedback loop includes a second summing junction coupled to at least a portion of the second output. The second summing junction receives a second command and provides an input to the first summing junction. The feedback loop reduces the step quantization from the first output to provide finer control step of a property of the second output.
    Type: Grant
    Filed: November 20, 2002
    Date of Patent: February 8, 2005
    Assignee: Spectra Physics, Inc.
    Inventor: Kevin Holsinger
  • Patent number: 6853567
    Abstract: The present invention relates to a pumping voltage generator configured to effectively generate a pumping voltage VPP depending on voltage variation. The pumping voltage generator of the present invention comprises a detector, a cycle selecting unit, an oscillator, a control driver and a pumping unit. The detector detects a plurality of pumping voltage levels, and outputs a plurality of enable signals in response to the detected voltage levels. The cycle selecting unit outputs an oscillation cycle selecting signal for controlling an oscillation cycle of a pumping voltage in response to the plurality of enable signals. The oscillator enabled by one of the plurality of enable signals outputs an oscillation signal corresponding to the oscillation cycle selecting signal. The control driver outputs a pumping control signal for controlling the pumping operation in response to the oscillation signal. The pumping unit outputs the pumping voltage in response to the pumping control signal.
    Type: Grant
    Filed: June 30, 2003
    Date of Patent: February 8, 2005
    Assignee: Hynix Semiconductor Inc.
    Inventor: Myeong Ju Kwon