Abstract: Compositions useful for reconstitution of concentrated formulations containing protein/peptide pharmaceuticals are provided. The composition generally includes one or more lipids, as well as one or more alcohols that promote and stabilize the formation of (a) lipid molecular assemblies with greater protein encapsulation; (b) protein-lipid complexes and (c) protein and lipid solutions. The reconstitution medium improves the protein-lipid association that in turn alters the pharmaceutical properties.

Abstract: A method of automatically programming an infusion pump includes scanning, via a machine-readable scanner wirelessly connected to the infusion pump, a machine-readable label for a drug container to automatically program the infusion pump according to a protocol included in the label. The machine-readable label for the drug container further includes a drug name and data associated with a drug corresponding to the drug name.

Abstract: The present invention relates to a device for controlling a brake of a microtome. The microtome (1) has an actuating element (2), a movement mechanism (8) and a brake. With the aid of the movement mechanism (8), an object to be cut can be moved relative to a knife blade. The actuating element (2) can be manually actuated by an operator and, as a result thereof, the relative motion between the object and the knife blade can be performed with the movement mechanism (8). The relative motion can be locked with the aid of the brake. So that the relative motion between the object and the knife blade can be used in a mechanically designed movement mechanism (8) and/or the relative motion can be locked without an additional hand movement of the operator, the inventive device is characterized by at least one sensor unit (5, 13). The sensor unit (5, 13) is provided on the actuating element (2) or adjacent to the actuating element (2). With the aid of the sensor unit (5, 13) a contact by the operator can be determined.

Abstract: A turning roll system for rotating a cylindrical workpiece about a workpiece axis comprises a pair of idler rollers cooperating with a pair of drive rollers to support the workpiece. To oppose axial drift of the workpiece, each idler roller is rotatably journalled on a respective idler axle such that the axis of rotation of the idler roller is oriented obliquely relative to a pivot axis of the idler axle. The idler axles may be pivoted about their respective pivot axes to adjust the orientation of the idler roller axes relative to the workpiece to introduce an axially directed force component acting on the workpiece to counter axial drift. Pivoting of the idler axles may be automatically controlled based on a signal generated by a drift sensor arranged to detect axial drift of the workpiece.

Abstract: An anti-free-flow mechanism includes an occluder mechanism which is disposed along a segment of tubing and a mounting structure. The occluder mechanism is normally in a biased closed position, but may be moved into an open position by placement in the mounting structure. However, unless force is applied to keep the occluder mechanism in the mounting structure, the occluder will move relative to the mounting structure and return to the first, closed position.

Abstract: The present invention relates to a tissue infiltration device (1) for samples (34) contained in cassettes (5). The tissue infiltration device (1) comprises at least two liquid containers (7, 11a-11d, 13, 15) and a transport apparatus (6). A liquid (12, 14, 16) having a property that can be predetermined can be filled into a liquid container (7, 11a-11d, 13, 15). A plurality of cassettes (5) can be held by a transport device (4). Using the transport apparatus (6), a transport device (4) can be brought to a liquid container (7, 11a-11d, 13, 15) and/or moved away from a liquid container (7, 11a-11d, 13, 15). A sequence of operations (8) can be prescribed in which a transport device (4) runs through the liquid containers (7, 11a-11d, 13, 15) of the tissue infiltration device (1).

Abstract: Provided herein are substituted pyrrolidines that demonstrate binding at biogenic amine transporters and can be synthesized by a methodology based on a chiral dirhodium catalyst. Compositions comprising substituted pyrrolidines can be used to treat central nervous system disorders such as schizophrenia.

Abstract: A diaphragm metering pump suitable for metering an effervescent gas. The pump has a pump head with a product chamber having an inlet end with a one-way inlet valve and an outlet end with a one-way outlet valve. A displaceable diaphragm member defines a boundary of the product chamber. The diaphragm member is capable of being reciprocated to cause pumping displacements. A discharge side is disposed downstream from the outlet valve. A passageway is disposed in fluid communication between the discharge side and the product chamber. A valve is disposed in the passageway. The valve is opened intermittently to allow liquid to re-enter the product chamber in an amount effective to purge gas from the product chamber to prevent loss of prime.

Abstract: A launderable and reusable, leak-proof, breathable fabric and, more specifically, a composite fabric comprised of a liquid absorptive layer and a liquid impervious but vapor permeable layer. Such fabric is useful in drawing fluids, such as bodily fluids, away from a source, such as the body, and retaining them within the absorptive layer while evaporation thereof takes place though the vapor permeable layer. This material consists of two juxtaposed layers. The inner layer has the characteristic of being liquid permeable so as to allow the body fluids to flow into it and be absorbed. The outer layer has the characteristic of being liquid impermeable but air or vapor permeable, so that the liquid absorbed in the inner layer does not strike through the outer layer.

Abstract: The invention relates to a method for operating a firing furnace, in particular for the dental sector, in which the temperature is measured and, based on the measured temperature, a temperature control is performed. If appropriate, the temperature integral, recorded at discrete points, is determined over the course of time and in particular stored, and is used, if appropriate in addition to the temperature, for controlling the firing furnace.

Abstract: Provided is a method for enhancing an immune response to a desired antigen in an individual. The method is performed by administering to the individual an agent capable of inhibiting class A macrophage scavenger receptor (SR-A) and optionally administering the desired antigen. Also provided is a method for enhancing an immune response to an antigen by administering to an individual a composition containing antigen presenting cells that are characterized by specifically inhibited SR-A. Substantially purified populations of mammalian dendritic cells characterized by specifically inhibited SR-A are also provided.

Abstract: The present invention relates to a microtome (1) having functional regions to be operated manually, in particular a sample holder (2), a cutting device (3), a section removal system (4), and a section collection pan (5). A microtome (1) is described in which the particularly firm contact or adhesion of sectioning waste fragments and, in particular, of thin sections can be at least largely avoided. For this purpose, the microtome (1) according to the present invention is characterized in that the components of the microtome (1) that can be brought into contact with paraffin sections are embodied in electrically conductive fashion.

Abstract: A wedge-lock system for injection molds, using a protrusion on one side of the mold and a mating opening and sets of wedges which act together upon mold closing to provide and maintain accurate centering of the core and cavity halves in reference to each other, to prevent core shifts and compensate for uneven thermal expansion of mold components.

Abstract: An angle trim (20) is provided. The angle trim (20) includes a first elongated strip (22) having first (24) and second (26) opposed ends. A second elongated strip (28) projects at an angle from an elongated side (30) of the first strip (22) along the length of the elongated side (30). A tongue member (32) extends from the first end (24) of the first strip (22) at a raised height above the upper surface of the first strip (22). A channel (34) is arranged adjacent the second end (26) of the first strip (22) above the upper surface. The channel (34) is adapted to receive the tongue member (32) of another angle trim to connect the angle trims in an end to end relationship without requiring overlap of the first strips of the angle trims.

Abstract: A Langevin transducer horn uses split electroding or selective electroding of transducer elements and phase relationships of the voltages applied thereto to determine the relative longitudinal and flexural/transverse motion induced in the tip of the horn.

Abstract: A tissue processor for treating tissue samples comprises a process chamber (10) in which the tissue samples can be treated with at least one liquid. The process chamber (10) is formed as a vessel of a magnetic stirrer. In the process chamber, a stirring body (16) for stirring the liquid is arranged, wherein the stirring body (16) comprises at least one magnet (40a, 40b) with the aid of which the stirring body (16) can be set in rotation by a drive unit (20) of the magnetic stirrer, and at least one vane (28a to 28f) by which the liquid to be stirred is stirred when the stirring body (16) rotates. According to a first aspect of the invention, the stirring body (16) has at least three vanes (28a to 28f), according to a second aspect of the invention, the stirring body (16) has at least one further magnet (40b). The north pole (46) of the one magnet (40a) and the south pole (50) of the further magnet (40b) face the drive unit (20).

Abstract: A dispensing device having a housing capable of receiving a pre-packaged charge of pre-whipped topping or icing. The housing has an inner wall with a slot formed therein for receiving a rack that is capable of rotational and translational motion within the slot. The rack has a set of gear teeth that engage with a catch on a plunger. The piston moves in the axial direction to force the pre-whipped topping or icing through the outlet in its packaging. The catch on the piston is locked in one direction and pivots in the opposite direction such that the rack engages with the piston when it moves in a first direction and the rack disengages with the piston when it is moved in a second direction opposite the first direction.

Abstract: An electromagnetic filter, which may include a feed-through conductor. The feed-through conductor may have an integral extension for contacting an electrically conductive clip. The clip may have an extension-engaging portion to contact the extension and a dielectric component-contacting end to contact a dielectric component. The dielectric component may be, for example, a varistor, a chip capacitor, or the like, capable of affecting a signal carried by the feed-through conductor. The dielectric component may be proximate to the feed-through conductor and may be oriented such that a primary dimension of the dielectric component is substantially parallel to the feed-through conductor. Another embodiment may include a bus. The invention may also be embodied as methods for assembling electromagnetic filters.