Abstract: Pharmaceutical compositions including N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1) and methods of using such compositions are described herein.
Type:
Grant
Filed:
May 14, 2007
Date of Patent:
June 30, 2009
Assignee:
Vertex Pharmaceuticals Incorporated
Inventors:
Christopher R. Young, Charles William Rowe
Abstract: The present invention relates to methods and compositions for the inhibition of gene expression. In particular, the present invention provides oligonucleotide-based therapeutics for the inhibition of oncogenes involved in cancers.
Type:
Grant
Filed:
June 1, 2004
Date of Patent:
March 3, 2009
Assignee:
ProNAI Therapeutics, Inc.
Inventors:
Gholamreza Sheikhnehjad, Mina Patel Sooch, Neal Goodwin, David Olson