Abstract: The invention provides a human SMN-like protein (HSLP) and polynucleotides which identify and encode HSLP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HSLP.
Type:
Grant
Filed:
May 15, 2000
Date of Patent:
September 16, 2003
Assignee:
Incyte Corporation
Inventors:
Y. Tom Tang, Neil C. Corley, Karl J. Guegler
Abstract: The invention provides a new human cathepsin (LCAP) and polynucleotides which identify and encode LCAP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of LCAP.
Type:
Grant
Filed:
March 7, 2000
Date of Patent:
September 16, 2003
Assignee:
Incyte Corporation
Inventors:
Olga Bandman, Karl J. Guegler, Neil C. Corley, Purvi Shah
Abstract: The invention provides a human E1-like protein (HELPR) and polynucleotides which identify and encode HELPR. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of HELPR.
Abstract: The present invention relates to a composition comprising a plurality of polynucleotide probes. The composition can be used as hybridizable array elements in a microarray. The present invention also relates to a method for selecting polynucleotide probes for the composition.
Type:
Grant
Filed:
February 9, 1998
Date of Patent:
August 19, 2003
Assignee:
Incyte Corporation
Inventors:
Benjamin G. Cocks, Susan G. Stuart, Jeffrey J. Seilhamer
Abstract: The invention provides compositions and novel polynucleotides and proteins that co-express with known marker genes for inflammatory disorders. The invention also provides expression vectors, host cells, proteins encoded by the polynucleotides and antibodies which specifically bind the proteins. The invention also provides methods for the diagnosis, prognosis, evaluation of therapies and treatment of inflammatory disorders.
Type:
Grant
Filed:
May 14, 2001
Date of Patent:
August 5, 2003
Assignee:
Incyte Corporation
Inventors:
Michael G. Walker, Wayne Volkmuth, Tod M. Klingler
Abstract: The invention provides a human ankyrin family protein (ANFP) and polynucleotides which identify and encode ANFP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of ANFP.
Type:
Grant
Filed:
September 23, 1999
Date of Patent:
July 8, 2003
Assignee:
Incyte Corporation
Inventors:
Y. Tom Tang, Karl J. Guegler, Neil C. Corley, Henry Yue