Patents Represented by Attorney, Agent or Law Firm Incyte Pharmaceuticals, Inc.
  • Human S100 proteins
    Patent number: 6103497
    Abstract: The invention provides two human S100 proteins designated individually as S100P1 and S10OP2 and collectively as S100P, and polynucleotides which identify and encode S100P. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of S100P.
    Type: Grant
    Filed: December 4, 1998
    Date of Patent: August 15, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Olga Bandman, Neil C. Corley, Preeti Lal, Purvi Shah
  • NADH dehydrogenase B17 subunit
    Patent number: 6100036
    Abstract: The invention provides a human NADH dehydrogenase B17 subunit (NDB17) and polynucleotides which identify and encode NDB17. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of NDB17.
    Type: Grant
    Filed: December 15, 1998
    Date of Patent: August 8, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Preeti Lal, Y. Tom Tang, Neil C. Corley
  • Delta 1-pyrroline-5-carboxylate reductase homolog
    Patent number: 6100075
    Abstract: The invention provides a human delta 1-pyrroline-5-carboxylate reductase homolog (P5CRH) and polynucleotides which identify and encode P5CRH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of P5CRH.
    Type: Grant
    Filed: June 18, 1998
    Date of Patent: August 8, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Neil C. Corley, Mariah R. Baughn
  • Human cyclic nucleotide PDEs
    Patent number: 6100037
    Abstract: The invention provides human cyclic nucleotide phosphodiesterases (HSPDE10A) and polynucleotides which identify and encode HSPDE10A. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of HSPDE10A.
    Type: Grant
    Filed: January 7, 1999
    Date of Patent: August 8, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Stephen C. Phillips, Jeremy Lanfear, Lindsay Fawcett, Olga Bandman
  • Human nucleic acid methylases
    Patent number: 6096526
    Abstract: The invention provides a human nucleic acid methylases (HNAM) and polynucleotides which identify and encode HNAM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of HNAM.
    Type: Grant
    Filed: May 20, 1998
    Date of Patent: August 1, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Preeti Lal, Neil C. Corley, Karl J. Guegler, Henry Yue
  • Human lysophospholipase
    Patent number: 6093561
    Abstract: The invention provides a human lysophospholipase (NHLP) and polynucleotides which identify and encode NHLP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of NHLP.
    Type: Grant
    Filed: December 18, 1998
    Date of Patent: July 25, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Purvi Shah, Lynn E. Murry
  • Protein phosphatase regulatory subunit
    Patent number: 6093565
    Abstract: The present invention provides a human protein phosphatase regulatory subunit (HCNB) and polynucleotides which identify and encode HCNB. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HCNB and a method for producing HCNB. The invention also provides for agonists, antibodies, or antagonists specifically binding HCNB, and their use, in the prevention and treatment of diseases associated with expression of HCNB. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HCNB for the treatment of diseases associated with the expression of HCNB. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HCNB.
    Type: Grant
    Filed: December 12, 1996
    Date of Patent: July 25, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Surya K. Goli
  • Monocyte activating cytokine
    Patent number: 6090377
    Abstract: The present invention provides novel monocyte activating cytokine (MAC) and a polynucleotide encoding MAC. The invention also provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequence encoding MAC. The invention also provides for the production and use of substantially purified MAC in pharmaceutical compositions for the treatment of cancer and disease of the immune system. The invention also describes diagnostic assays which utilize the polynucleotide to hybridize with the transcripts encoding MAC and antibodies which specifically bind to MAC.
    Type: Grant
    Filed: July 28, 1998
    Date of Patent: July 18, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Roger Coleman, Janice Au-Young, Lynn E. Murry
  • SnRNP Sm proteins
    Patent number: 6090564
    Abstract: The present invention provides novel human small nuclear ribonucleoprotein (snRNP) Sm proteins (collectively called HSMP) and polynucleotides which identify and encode HSMP. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HSMP. The invention also provides pharmaceutical compositions containing HSMP or antagonists to HSMP, and in the use of these compositions for the treatment of diseases associated with the expression of HSMP. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HSMP for the treatment of diseases associated with the expression of HSMP. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, to hybridize to the genomic sequence or transcripts of polynucleotides encoding HSMP or anti-HSMP antibodies which specifically bind to HSMP.
    Type: Grant
    Filed: December 2, 1998
    Date of Patent: July 18, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Olga Bandman, Gary B. Zweiger
  • Disease associated acidic protein
    Patent number: 6090577
    Abstract: The invention provides a human disease associated acidic protein and polynucleotides which identify and encode DAAP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of DAAP.
    Type: Grant
    Filed: May 22, 1997
    Date of Patent: July 18, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Surya K. Goli
  • Disease associated acidic protein
    Patent number: 6087333
    Abstract: The invention provides a human disease associated acidic protein and polynucleotides which identify and encode DAAP. The invention also provides expression vectors, host cells. agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of DAAP.
    Type: Grant
    Filed: August 24, 1999
    Date of Patent: July 11, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Surya K. Goli
  • Polynucleotide encoding a novel human nm23-like protein
    Patent number: 6087125
    Abstract: The present invention provides polynucleotides which identify and encode a novel human nm23-like protein (H-nm23). The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequence encoding H-nm23 and for a method for producing the protein. The invention also provides for the use of substantially purified H-nm23 for the treatment of diseases associated with the expression of H-nm23. The invention also describes diagnostic assays which utilize diagnostic compositions comprising the polynucleotides which hybridize with naturally occurring sequences encoding H-nm23 and antibodies which specifically bind to the protein.
    Type: Grant
    Filed: November 24, 1998
    Date of Patent: July 11, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Phillip R. Hawkins
  • RNA editing enzyme
    Patent number: 6087108
    Abstract: The present invention provides a human RNA editing enzyme (REE-2) and polynucleotides which identify and encode REE-2. The invention also provides expression vectors and host cells, agonists, antibodies, or antagonists. The invention provides methods for producing REE-2 and for treating diseases associated with expression of REE-2.
    Type: Grant
    Filed: August 3, 1998
    Date of Patent: July 11, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Surya K. Goli
  • Human cytochrome b5
    Patent number: 6083704
    Abstract: The present invention provides a human cytochrome b5 (HCB5) and polynucleotides which encode HCB5. The invention also provides genetically engineered expression vectors and host cells and a method for producing HCBS. The invention also provides for agonists, antisense molecules, antibodies, or antagonists of HCB5, and their use in the prevention and treatment of diseases associated with expression of HCB5. The invention also provides a method for detecting polynucleotides which encode HCB5.
    Type: Grant
    Filed: October 26, 1998
    Date of Patent: July 4, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Surya K. Goli, David Gray Streeter
  • Human goose-type lysozyme
    Patent number: 6083700
    Abstract: The invention provides a human goose-type lysozyme (GOLY) and polynucleotides which identify and encode GOLY. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of GOLY.
    Type: Grant
    Filed: June 26, 1998
    Date of Patent: July 4, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Preeti Lal, Karl J. Guegler, Neil C. Corley, Chandra Patterson
  • Human actVA-ORF4-like protein
    Patent number: 6080723
    Abstract: The invention provides a human actVA-ORF4-like protein (A-ORFP) and polynucleotides which identify and encode A-ORFP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of A-ORFP.
    Type: Grant
    Filed: December 18, 1998
    Date of Patent: June 27, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Preeti Lal, Tom Tang, Neil C. Corley, Purvi Shah
  • Polynucleotide encoding human growth regulator protein
    Patent number: 6080558
    Abstract: The invention provides a new human growth regulator protein (GRREG) and polynucleotides which identify and encode GRREG. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of GRREG.
    Type: Grant
    Filed: July 11, 1997
    Date of Patent: June 27, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Olga Bandman, Preeti Lal, Purvi Shah, Neil C. Corley
  • Cyclic nucleotide phosphodiesterases
    Patent number: 6080548
    Abstract: The invention provides human cyclic nucleotide phosphodiesterases (PDE8) and polynucleotides which identify and encode PDE8. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of PDE8.
    Type: Grant
    Filed: February 23, 1999
    Date of Patent: June 27, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Janice Au-Young, Benjamin G. Cocks, Roger Coleman, Jeffrey J. Seilhamer, Douglas A. Fisher
  • Proteins associated with cell proliferation
    Patent number: 6080847
    Abstract: The invention provides three human proteins associated with cell proliferation, referred to collectively as "APOP" and individually as "APOP-1", "APOP-2", and "APOP-3", and polynucleotides which identify and encode APOP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for preventing and treating disorders associated with expression of APOP.
    Type: Grant
    Filed: December 4, 1997
    Date of Patent: June 27, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Jennifer L. Hillman, Henry Yue, Preeti Lal, Purvi Shah, Neil C. Corley
  • Human brain associated protein
    Patent number: 6080848
    Abstract: The invention provides a human human brain-associated protein (HBAP-1) and polynucleotides which identify and encode HBAP-1. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating or preventing disorders associated with expression of HBAP-1.
    Type: Grant
    Filed: May 1, 1998
    Date of Patent: June 27, 2000
    Assignee: Incyte Pharmaceuticals, Inc.
    Inventors: Sven Henrichwark, Janice Au-Young, Karl J. Guegler, Neil C. Corley, Mariah R. Baughn