Patents Represented by Law Firm Jacobs & Jacobs
  • Patent number: 4918067
    Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt or in-vivo hydrolysable ester thereof: ##STR1## wherein R.sup.1 is a 5 or 6 membered sulphur and/or nitrogen containing heterocyclic group substituted by an optionally protected amino group, with the proviso that R.sup.1 is not 2-aminothiazol-4-yl, and R is hydrogen; optionally substituted C.sub.1-12 alkyl; optionally substituted C.sub.2-12 alkenyl or alkynyl; carbocyclyl; aryl or heterocyclyl.These compounds have antibacterial properties, and therefore are of use in the treatment of bacterial infections in humans and animals caused by a wide range of organizations.
    Type: Grant
    Filed: July 22, 1987
    Date of Patent: April 17, 1990
    Assignee: Beecham Group p.l.c.
    Inventors: Brian C. Gasson, Michael J. Pearson
  • Patent number: 4917894
    Abstract: An oral anesthetic composition comprising an anesthetically effective amount of a compound of formula (I) ##STR1## wherein R is alkyl of 2 to 8 carbon atoms or a pharmaceutically acceptable salt thereof and an anesthetically effective amount of a rapid-onset anesthetic selected from the group consisting of benzyl alcohol, phenol, phenolate sodium, hexylresorcinol, menthol, salicyl alcohol and benzocaine in combination with a pharmaceutically acceptable carrier, said carrier being in orally administrable form.
    Type: Grant
    Filed: June 29, 1988
    Date of Patent: April 17, 1990
    Assignee: Beecham Inc.
    Inventors: Joseph A. Matthias, Kim L. Bildstein
  • Patent number: 4917954
    Abstract: Cured resins of high fracture toughness are prepared from N,N'-bisimides of formula I ##STR1## and alkenyl compounds of formula IID(G).sub.m IIin which D is an m-valent group and G represents a phenyl ring having at least one alkenyl (e.g. allyl or 1-propenyl) substituent.
    Type: Grant
    Filed: November 30, 1988
    Date of Patent: April 17, 1990
    Assignee: Technochemie GmbH
    Inventors: Horst Stenzenberger, Peter Koenig
  • Patent number: 4915228
    Abstract: A dressing delivery system comprising an adhesive-coated dressing, a release liner and a package are arranged such that the package acts as the means for applying the dressing to a skin area, with the opening of the package and the application of the dressing being accomplished in a single step. A simple method of preparing the dressing delivery system is also described.
    Type: Grant
    Filed: August 4, 1988
    Date of Patent: April 10, 1990
    Assignee: Smith & Nephew United, Inc.
    Inventor: Owen L. Johns
  • Patent number: 4915545
    Abstract: The large-sized underground storage tank is consisting of a metal shell (1), a static facing in reinforced or unreinforced concrete (2) and filling material (4) packed in the hollow space between the two above mentioned surfaces; this filling is consisting of blown bitumen having plasticity properties which provide a stress resisting interaction between the tank shell and its static facing, thus greatly improving the stability of the overall tank structure; hence the possibility to reduce the design strength parameters and to cut the cost of the final product.
    Type: Grant
    Filed: June 29, 1988
    Date of Patent: April 10, 1990
    Assignee: Nino Ferrari USA Inc.
    Inventor: Franco Ferrari
  • Patent number: 4916436
    Abstract: A warning apparatus alerts a home owner to unsafe temperatures in the stove pipe of a wood- or coal-burning stove by signaling an alarm if the pipe gets too hot, thereby providing a warning against a potential fire hazard that can be caused by creosote build-up.
    Type: Grant
    Filed: November 25, 1988
    Date of Patent: April 10, 1990
    Assignee: Consumer Products International, Inc.
    Inventors: Mike Silliman, Kevin Miles, Edward Reynolds
  • Patent number: 4915227
    Abstract: A dressing delivery system comprising an adhesive-coated dressing, a release liner and a package are arranged such that the package acts as the means for applying the dressing to a skin area, with the opening of the package and the application of the dressing being accomplished in a single step. A simple method of preparing the dressing delivery system is also described.
    Type: Grant
    Filed: July 28, 1989
    Date of Patent: April 10, 1990
    Assignee: Smith & Nephew United, Inc.
    Inventor: Owen L. Johns
  • Patent number: 4914195
    Abstract: A new process for preparing halides of N-acetylneuraminic acids useful as an intermediate in preparing new N-acetylneuraminic acid derivatives having an excellent immunological activity is provided, which process comprises simultaneously acetylating and halogenating an esterified N-acetylneuraminic acid with the aid of an acetyl halide, and according to the process, the halides may be obtained in high yield of about 90%.
    Type: Grant
    Filed: November 26, 1984
    Date of Patent: April 3, 1990
    Assignee: MECT Corporation
    Inventors: Haruo Ogura, Kimio Furuhata, Yoshiyasu Shitori, Masayoshi Ito
  • Patent number: 4914173
    Abstract: Skin friendly pressure sensitive adhesives in the form of inherently tacky polyurethane-containing gells may be prepared by reacting an isocyanate prepolymer, which is itself the reaction product of poly-functional isocyanate and polyoxyalkylene diol monoalkyl ether, with a hydroxyl-containing ester of acrylic or methacrylic acid and optionally other hydroxyl containing compounds and then cross-linking the polymer so formed by means of irradiation. The proportion of acrylate chosen is such that it will react with at least 15 to 25% of the free isocyanate groups in the prepolymer and the remainder react with the other hydroxyl containing compound. The adhesives are capable of absorbing up to 95%, typically from 35 to 95% by weight of water when hydrated. The use of the adhesive in highly moisture vapor permeable dressings is also disclosed.
    Type: Grant
    Filed: November 14, 1988
    Date of Patent: April 3, 1990
    Assignee: Smith and Nephew Associate Companies plc
    Inventor: Christopher W. G. Ansell
  • Patent number: 4908204
    Abstract: A fibrinolytically active hybrid protein which comprises one chain of a 2-chain protease linked to a chain of a different 2-chain protease, or to the same chain of the same protease, at least one of the chains in the hybrid protein being derived from a fibrinolytically active protease, such that the hybrid protein has a catalytic site essential for fibrinolytic activity which is optionally blocked by a removable blocking group.
    Type: Grant
    Filed: February 22, 1988
    Date of Patent: March 13, 1990
    Assignee: Beecham Group p.l.c.
    Inventors: Jeffery H. Robinson, Ian Dodd
  • Patent number: 4906620
    Abstract: New Medicament comprising as active ingredient a N.sup.6 -substituted adenosine of formula I ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are each independently hydrogen or acyl R.sub.4 -CO- in which R.sub.4 is alkyl, aryl, heteroaryl or aralkyl.
    Type: Grant
    Filed: January 13, 1989
    Date of Patent: March 6, 1990
    Assignee: Centre d'Etudes Experimentales et Cliniques de Physio-Biologie de Pharmacologie et d'Eutonologie (CEPBEPE) and Centre National de la Recherche Scientifique
    Inventors: Henri Laborit, Camille George Wemuth
  • Patent number: 4906464
    Abstract: A method for preparing a dispersion containing antibiotic powder comprises mixing the antibiotic powder and a dispersing medium at a temperature at which the dispersing medium is in the form of a liquid under a reduced pressure of not more than 470 Torr. According to this method, the antibiotic powder is uniformly dispersed in various dispersing mediums and antibiotic products having high antibiotic action is effectively be provided by using the resulting dispersion.
    Type: Grant
    Filed: December 21, 1988
    Date of Patent: March 6, 1990
    Assignees: Shinagawa Fuel Co., Ltd., Shinanen New Ceramic Corporation
    Inventors: Tatuo Yamamoto, Masashi Uchida, Yasuo Kurihara, Ichiro Nakayama
  • Patent number: 4903710
    Abstract: A surgical isolation drape for use in urological, gynaecological or proctorlogical surgical procedures or examination of patients comprises a sheet (10) of flexible transparent or translucent plastics material provided with adhesive strips (13, 14) and/or tapes (131, 141) for attaching the upper end of the sheet to the patient's legs so that the remainder of the sheet hangs down therefrom. The lower portion of the sheet is formed into a funnel (30) either by seaming its edge portions (221, 231) together or by means of attachment means such as tapes (15 to 20) for joining the sides of the lower part of the sheet. A central part of the sheet is provided with apertures (24, 25) sealed by flexible members such as surgical gloves (26, 27) which permit passage of the surgeon's hands. For urological use, the central portion also ha a sealable aperture (28) permitting ocular access to the lens of a urological instrument and a support for the lens casing, e.g.
    Type: Grant
    Filed: January 5, 1988
    Date of Patent: February 27, 1990
    Inventors: John G. Jessamine, Martin Taube
  • Patent number: 4904784
    Abstract: A compound of formula (I) or a pharmaceutically acceptable salt thereof: ##STR1## wherein all the symbols are defined in the specification; having pharmacological activity, including blood pressure lowering activity, a process and intermediates for their preparation and their use as pharmaceuticals.
    Type: Grant
    Filed: February 23, 1989
    Date of Patent: February 27, 1990
    Assignee: Beecham Group p.l.c.
    Inventors: John M. Evans, Geoffrey Stemp, Frederick Cassidy
  • Patent number: 4903531
    Abstract: The gyrometer comprises a cavity filled with a fluid in the form of a body of revolution having an axis coinciding with the axis of a rotation to be measured. An excitation transducer and a measuring transducer are disposed on the wall of the cavity in a same cross section and offset at an angle of 90.degree.. The excitation transducer excites a first acoustic resonance mode of the cavity and the measuring transducer measures a second mode of resonance induced by Coriolis forces when the cavity is subjected to the rotation to be measured. Such a gyrometer, less sensitive to mechanical embodiment inaccuracies, is assembled on, a moving body, for example, in order to measure its speed(s) of rotation.
    Type: Grant
    Filed: September 1, 1988
    Date of Patent: February 27, 1990
    Assignee: Badin-Crouzet
    Inventors: Henri LeBlond, Philippe Herzog, Michel Bruneau
  • Patent number: 4899474
    Abstract: This open sleeve support is consisting of a central flat or slightly curved part (1), preferably of constant thickness, provided with two lateral branches (2) growing more narrow downwards, the latter being connected through a small fillet, to the two flat and parallel flanges (4) bent inwards and almost reaching the center of the sleeve, so that the support can be easily fitted on cables of various size (7) by slipping the sleeve on laterally, without risk of failure, while remaining firmly in place.
    Type: Grant
    Filed: October 29, 1984
    Date of Patent: February 13, 1990
    Assignee: Graphoplast S.p.A.
    Inventors: Ivana Piana, Silvano Piana
  • Patent number: D305960
    Type: Grant
    Filed: June 23, 1986
    Date of Patent: February 13, 1990
    Inventor: Stephen H. Wolff
  • Patent number: D306021
    Type: Grant
    Filed: August 6, 1987
    Date of Patent: February 13, 1990
    Assignee: Safare-Crouzet
    Inventor: Serge A. Cavalier
  • Patent number: D306584
    Type: Grant
    Filed: August 6, 1987
    Date of Patent: March 13, 1990
    Assignee: Safare-Crouzet
    Inventor: Serge A. Cavalier
  • Patent number: D306585
    Type: Grant
    Filed: August 6, 1987
    Date of Patent: March 13, 1990
    Assignee: Safare-Crouzet
    Inventor: Serge A. Cavalier