Abstract: Detergent compositions containing N-(1,2 propanediol) fatty acid amide surfactants of the general type RC(O)NR.sup.1 CH.sub.2 CHOHCH.sub.2 OH, especially where R.sup.1 is methyl or hydroxyethyl, are useful surfactants in laundry detergents, dishwashing liquids, shampoos, bar soaps, and hard surface cleaners. The amide surfactants provide good cleaning even in the absence of LAS surfactants.
Type:
Grant
Filed:
February 22, 1993
Date of Patent:
August 16, 1994
Assignee:
The Proctor & Gamble Co.
Inventors:
Daniel S. Connor, Jeffrey J. Scheibel, Yi-Chang Fu, Bruce P. Murch, Randall A. Watson, Kirsten L. McKillop
Abstract: Curled, twisted cellulosic fibers are reduced in size by mechanical means, i.e., by refining. The refined fibers are formed into sheets which are used as an absorbent layer in diapers, bandages and, especially, in sanitary napkins. In one mode, the refined fibers can be used to provide shaped sanitary devices. In an optional mode, fibers having intra-fiber capillary channels can be used to direct fluids into absorbent sheets comprising the refined, curled cellulosic fibers.
Type:
Grant
Filed:
July 23, 1991
Date of Patent:
August 2, 1994
Assignee:
The Procter & Gamble Company
Inventors:
Daniel E. Buenger, James C. Horney, John L. Hammons
Abstract: Amines such as methyl amine are reacted with materials such as reducing sugars in hydroxy solvents such as methanol to prepare N-alkyl polyhydroxy amines. Accordingly, glucose is reacted with methyl amine and the resulting adduct is hydrogenated to yield N-methylglucamine. The N-alkyl polyhydroxyamines can be subsequently reacted with fatty esters to provide polyhydroxy fatty acid amides useful as detersive surfactants. Thus, detersive surfactants are available from non-petrochemical precursors such as sugars and sugar sources such as corn syrup, and fatty acid esters derivable from various fats and oils.
Type:
Grant
Filed:
May 6, 1993
Date of Patent:
August 2, 1994
Assignee:
The Procter & Gamble Company
Inventors:
Jeffrey J. Scheibel, Daniel S. Connor, Robert E. Shumate, James B. St. Laurent
Abstract: Amino-functional compounds are economically prepared by reacting maleic anhydride with alcohols to form a maleate or fumarate "half-ester" which is combined with certain amines, most preferably aspartate or glutamate, under conditions selected to avoid hydrolysis. At low molecular weights, the compounds herein are useful detergency builders; at progressively higher molecular weights within a specific range, combined builder/dispersant and typical dispersant properties emerge. Processes for preparing the compounds and useful detergent compositions containing them are described.
Type:
Grant
Filed:
March 30, 1993
Date of Patent:
July 26, 1994
Assignee:
The Procter & Gamble Company
Inventors:
Stephen W. Heinzman, Michael J. Eis, Molly P. Armstrong
Abstract: Disclosed is a detergent composition containing one or more anionic surfactants and one or more soil release agents characterized by the presence of an anionic surfactant-interactive nonionic hydrophile and/or an anionic surfactant-interactive hydrophobic moiety, or both, and a soil release agent-enhancing amount of a polyhydroxy fatty acid amide surfactant of the formula: ##STR1## wherein R.sup.1 is H, C.sub.1 -C.sub.4 hydrocarbyl, 2-hydroxy ethyl, 2-hydroxy propyl, or a mixture thereof, R.sub.2 is C.sub.5 -C.sub.31 hydrocarbyl, and Z is a polyhydroxylhydrocarbyl having a linear hydrocarbyl chain with at least 3 hydroxyls directly connected to the chain, or an alkoxylated derivative thereof.
Abstract: Low-sudsing detergent compositions comprise an N-alkyl polyhydroxy fatty acid amide surfactant, wherein the N-alkyl substituent is at least C.sub.2, preferably C.sub.3 -C.sub.8. Such compositions are useful under cleaning conditions where excessive sudsing may be problematic.
Type:
Grant
Filed:
November 30, 1992
Date of Patent:
June 7, 1994
Assignee:
The Procter & Gamble Company
Inventors:
Athanasios Surutzidis, Jean-Pol Boutique, Yi-Chang Fu, Bruce P. Murch, Daniel S. Connor, Jeffrey J. Scheibel
Abstract: Polyhydroxy fatty acid amide nonionic surfactants are converted in high yields to their sulfated analog surfactants using an SO.sub.3 /pyridine complex as a sulfating agent. Thus, C.sub.12 -C.sub.18 N-methyl glucamide is sulfated in methylene chloride or pyridine solvent to form the corresponding sulfated glucamide in yields of 80% or higher.
Abstract: Compositions comprise absorbent gelling materials combined with high levels of odor-controlling agents by means of binders. The preferred particle form of the compositions is easy to handle, and is used in the manufacture of catamenials, diapers, bandages, and the like. The absorbent gelling material enhances the odor-controlling properties of the compositions by helping to control ammonia odors.
Abstract: Polyhydroxy amines reacted with fatty acid esters yield polyhydroxy fatty acid amide surfactants, such as the C.sub.11 -C.sub.17 fatty N-methyl glucamides, which may be contaminated with secondary amines. Such amines are acylated by a reaction with acetic anhydride. The resulting "clean" polyhydroxy fatty acid amide surfactants are preferred for use in the presence of oxidants, especially in the formulation of modern, colorless liquid detergents.
Abstract: Near-quantitative conversion of maleate to D,L-malate is rapidly secured by heating an aqueous alkaline mixture of maleate and excess of the divalent cations calcium, magnesium or mixtures thereof in a reactor at autogenous pressures and at temperatures above reflux. The simplest raw materials for the process are maleic anhydride and calcium hydroxide. The product is secured as an unusual, typically granular solid form of the divalent metal malate salt which is very useful in processes for preparing other malate salts, malic acid, or 2,2'-oxodisuccinate laundry detergent builders.
Type:
Grant
Filed:
December 10, 1987
Date of Patent:
March 29, 1994
Assignee:
The Procter & Gamble Company
Inventors:
Daniel S. Connor, Herbert C. Kretschmar
Abstract: The present invention relates to compositions and methods for inhibiting plaque. In particular, this invention relates to oral compositions comprising: (a) a safe and effective amount of a carboxy-substituted polymer active agent having the formula ##STR1## or the salts thereof, wherein R is a C.sub.1 -C.sub.8 alkyl group, n is in the range of from 0 to about 2,000, m is in the range of from about 10 to about 2,000, and p is in the range of from about 1 to about 10; and (b) a pharmaceutically acceptable carrier. These compositions inhibit plaque without staining the tooth surfaces which are contacted with the composition.This invention also relates to a method of inhibiting plaque on tooth surfaces in the oral cavity. This method involves applying a safe and effective amount of the carboxy-substituted polymer active agent to the oral cavity. Such an application is typically made by applying the above-described oral compositions containing the carboxy-substituted polymer to the tooth surface.
Type:
Grant
Filed:
April 26, 1993
Date of Patent:
March 8, 1994
Inventors:
Charles R. Degenhardt, Barbara A. Kozikowski
Abstract: Homogeneous polymer blends are prepared from otherwise thermodynamically immiscible polymers. Thus, mixtures of polymers such as poly (methyl methacrylate) and poly (ethyl methacrylate) are dissolved under pressure in supercritical fluid solvents such as chlorodifluoromethane and expanded through a fine nozzle. As the SCF solvent evaporates, the polymer mixture deposits as a substantially homogeneous blend.
Abstract: The subject invention encompasses methods and compositions comprising N-acetylated amino acid complexes for reducing or preventing dental plaque, calculus, or gingival or periodontol diseases of the oral cavity in humans or lower animals.
Abstract: Fibers having intra-fiber capillary channels are used in conjunction with topsheet materials in absorbent articles such as diapers, bandages and, especially, sanitary napkins. In-use, the capillary channel fibers draw fluid away from the topsheet to provide a clean, dry appearance.
Abstract: The subject invention relates to compositions in dosage form comprising a solid dispersion which is a solidified melt mixture consisting essentially of the following components:(a) from about 15% to about 75% of tebufelone;(b) from about 25% to about 65% of a poloxamer surfactant having a melting point of about 40.degree. C. or greater, the poloxamer surfactant consisting essentially of a block copolymer having three polymer blocks, a middle block of poly(oxypropylene) with a molecular weight of from about 1450 daltons to about 6000 daltons, and end blocks of poly(oxyethylene), the end blocks being from about 50% to about 90% of the copolymer; and(c) from 0% to about 60% of other components, wherein the other components are miscible with a melt mixture of components (a) and (b).
Abstract: The present invention relates to a novel cell line isolated from a rat osteosarcoma wherein the cell line has the following characteristics: a) a mutated p53 gene incapable of expressing p53 protein, b) a normal RB-1 gene, c) a 10-fold amplified c-myc gene, d) a normal c-fos gene, e) a deregulated immediate early gene response, f) a canalicular network MATRIGEL.TM. growth pattern, g) tumorigenic in congenitally athymic mice, h) no alkaline phosphatase activity, i) an ability to produce one or more growth factors selected from the group consisting of: 1) an osteoblastic differentiation growth factor, 2) a non-heparin binding mitogenic growth factor, 3) a first heparin binding mitogenic growth factor, 4) a second heparin binding mitogenic growth factor, and 5) a third heparin binding mitogenic growth factor, and j) an ability to be serially propagated greater than sixty population doublings.
Type:
Grant
Filed:
June 24, 1992
Date of Patent:
November 23, 1993
Assignee:
The Procter & Gamble Company
Inventors:
Claus-Jens W. Doersen, Robert J. Isfort
Abstract: Bar soaps containing polyhydroxy fatty acid amides exhibit good "smear" qualities, desirable hardness and good lather properties. The bars also have a decreased tendency to crack. Bars comprising soap and materials such as C.sub.12 -C.sub.18 N-methyl glucamide are provided.
Abstract: The present invention relates to a composition for regulating hair growth comprising a safe and effective amount of the tripeptide histidyl-glycyl-glycine, or a derivative thereof, and a pharmaceutically-acceptable carrier.
Type:
Grant
Filed:
August 20, 1991
Date of Patent:
October 12, 1993
Assignee:
The Procter & Gamble Company
Inventors:
Kurt G. Kronholm, Richard J. Schwen, Mark R. Sine, Raphael Warren, Cynthia J. Wawrzyniak
Abstract: A process and extrusion die for making capillary channel structures having one or more intrastructure capillary channels. The process includes feeding a flowable, molten polymer composition through an extrusion die having an annular base orifice from which a plurality of capillary channel wall orifices radially extend. The extrusion die has a gas inlet port located interior to the annular base orifice. Simultaneous with feeding the polymer composition through the extrusion die's annular base and capillary channel wall orifices a gaseous stream is directed through the gas inlet port in the same direction as the flow of molten polymer composition. Subsequent to exit of the polymer composition from the extrusion die, the capillary channel structure is drawn to a desired size and cooled.