Patents Represented by Attorney John P. Kirby, Jr.
  • Patent number: 4402417
    Abstract: An opening ring (40) for a bottle (29) has a closure element (36) attached to the bottle neck (30) at a frangible section (38). The opening ring (40) includes rigid shock absorbing means such as a collar (58) to protect the bottle from unwanted opening of the frangible section (38) which would thereby destroy the seal, and in the case of bottle-stored sterile liquids, contaminate same.
    Type: Grant
    Filed: December 28, 1981
    Date of Patent: September 6, 1983
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: William C. Corrigan, Jr., Thomas A. Fowles, Nicholas Gibbons
  • Patent number: 4396383
    Abstract: A container having a unique two chamber construction provides for the passive mixing of two supply solutions having different specific gravities into a single homogenous solution in a closed environment. The container includes means for a positive test that a single homogenous solution has been achieved. The container is especially useful for storing and mixing two supply solutions which when mixed form a single medical solution which itself is unsuitable for storage over extended time periods.
    Type: Grant
    Filed: November 9, 1981
    Date of Patent: August 2, 1983
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventor: John W. Hart
  • Patent number: 4396385
    Abstract: Metering apparatus for controlling the flow of fluid through a fluid infusion system at an operator-designated rate includes a single-use cassette having a syringe-type pump in the flow system. The cassette is removably mounted on actuator apparatus which drives the syringe plunger through alternate fill and pump modes to advance fluid through the system. To provide compensation for the lack of flow in the system during fill strokes, the plunger is advanced at a higher compensation rate for first and second portions of the pump stroke immediately preceding and immediately following each fill stroke, with the pump stroke advancing at the designated rate therebetween. This results in an average flow rate which corresponds to the designated rate. By making the first and second compensations of equal duration, the effect of the fill cycles on the regularity of the average flow rate is minimized.
    Type: Grant
    Filed: December 5, 1980
    Date of Patent: August 2, 1983
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: Timothy G. Kelly, David A. Lohr, Peter A. St. John
  • Patent number: 4394862
    Abstract: Metering apparatus for metering the flow of fluid through an administration set includes a peristaltic-type metering pump which repeatedly and progressively compresses a section of vinyl tubing of the administration set to provide a desired flow rate. For improved metering accuracy the fluid is maintained under pressure downline of the metering pump by a downline occlusion station. A protective circuit responsive to the pressure in the tubing downline of the occlusion station stops the metering apparatus and sounds an alarm in the event the pressure in the tubing exceeds a predetermined level, as in the event of an occlusion, downline of the metering apparatus and upline of the patent.
    Type: Grant
    Filed: August 25, 1980
    Date of Patent: July 26, 1983
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventor: Norm Shim
  • Patent number: 4393909
    Abstract: An administration port (14) for medical fluid containers (10) is provided which creates a proper seal with a broad dimensional range of cannulas. The port includes an inwardly tapered end 28 which can flex outwardly during insertion of a cannula (16). The inwardly tapered end 28 works in conjunction with an inner surface (32) of the sidewall (18) and end (28) to provide a unique sealing construction, to minimize friction between the port (14) and the cannula (16) during insertion of the cannula (16) and to inhibit inadvertent removal of the cannula. Selective removal of the associated cannula requires relatively little force, however.
    Type: Grant
    Filed: December 28, 1981
    Date of Patent: July 19, 1983
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventor: Stephen Pearson
  • Patent number: 4378891
    Abstract: A one-piece integral plastic container is disclosed which has an outer closure or overcap removable along a frangible line of weakness, and a separately-formed inner closure that is maintained in sterile condition by the outer closure until the container contents are dispensed. The inner closure comprises a tubular member inserted in fluid-tight relationship within the container neck after the container body and neck are molded, but prior to formation of the outer closure. The tubular member thus provides the dispensing outlet for the container and is maintained in sterile condition by the overcap which encloses it.
    Type: Grant
    Filed: September 29, 1981
    Date of Patent: April 5, 1983
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: Thomas A. Fowles, Glenn L. Slater, David A. Winchell
  • Patent number: 4372100
    Abstract: A process and apparatus for mixing at least two parenteral solutions, sterilizing the resulting mixture, and transferring the sterilized mixture into an extensible, plastic receiving bag. The apparatus includes a mixing chamber into which the solutions can be delivered, a bacterial organism retentive filter for sterilizing the mixture of the solutions received from the chamber, such a receiving bag, tubing for transferring each of the solutions to be chamber, and second tubing for transferring the sterilized mixture from the filter to the bag. All are combined and then sterilized as a unit. In one embodiment of the invention, the bag is placed in a vacuum chamber to facilitate transfer of the mixture through the apparatus and the mixing chamber has a baffle or system of baffles for creating turbulence in the solutions while they are being mixed.
    Type: Grant
    Filed: December 17, 1981
    Date of Patent: February 8, 1983
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: Robert A. Miller, Kenneth W. Larson, Joseph L. Schopen
  • Patent number: 4368729
    Abstract: An improved flexible, collapsible container (10) for holding a sterile solution such as protein hydrolysate or amino acid solutions is disclosed, it being intended for sterile connection with another flexible, collapsible container (38) of carbohydrate solutions or the like. The two containers carry connector members (24, 34) of a specific design. A flexible tubular boot member (18) is provided to the container of this invention, which carries the connector and a tubular cannula (20) defining an inwardly-pointed spike adapted to penetrate puncturable diaphragm means (17) for opening the contents in sterile manner. The boot member is of a particular shape as disclosed to permit inward deflection of its end without forcing the sides to expand substantially outwardly.
    Type: Grant
    Filed: October 14, 1980
    Date of Patent: January 18, 1983
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventor: Luc M. Dossin
  • Patent number: 4367736
    Abstract: A system for use in flow metering apparatus for detecting bubble formation in both clear and opaque fluids in an administration set includes a light source and a light detector positioned on opposite sides of a transparent tubing segment of the administration set such that light transmitted through the tubing to the detector is dependent on the presence or absence of fluid in the tubing. With clear fluid present, a first comparator in the system interrupts operation of the metering apparatus when the light detector output falls below a predetermined minimum level. With opaque fluid present, a second comparator interrupts operation of the apparatus when the light detector output rises above a predetermined maximum level. The detection system is automatically conditioned to either clear or opaque operating modes without input from the operator, and incorporates protection circuitry for interrupting operation of the metering apparatus in the event of failure of either the light source or the light detector.
    Type: Grant
    Filed: August 25, 1980
    Date of Patent: January 11, 1983
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventor: John E. Gupton
  • Patent number: 4366913
    Abstract: A closure system for a container having a neck with a cap support flange extending radially outwardly around the neck. A resilient gasket encircles the neck and overlies the cap support flange, to be compressed by a closure cap which is attached to the neck for sealing. Annular rib means project from the support flange against the gasket to retain the gasket in its sealing position. A method is also described for the manufacturing of such a closure system.
    Type: Grant
    Filed: October 17, 1980
    Date of Patent: January 4, 1983
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: David A. Winchell, Thomas A. Fowles
  • Patent number: 4360435
    Abstract: A process for sterilizing a solution and thereafter transferring it to a solution container for storage. A sterilizing filter, flexible tubing and the solution container are provided as a pre-sterilized unit with a label indicating that the unit is sterile. A source of solution to be transferred is connected to an inlet of the sterilizing filter, and the solution is sterilized by transferring it from the source and through the sterilizing filter to the container via the flexible tubing. The integrity of the filter is determined by introducing a pressurized gas into the filter and observing through a light-transmissive portion in the sterile unit for gas bubbles, which would indicate a loss of filter integrity and unit sterility.
    Type: Grant
    Filed: November 1, 1979
    Date of Patent: November 23, 1982
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: David Bellamy, John L. Quick
  • Patent number: 4346704
    Abstract: A sleeve valve is carried in a parenteral solution administration device. The valve comprises an outer housing (30) defining an outlet tube (28); an inner tubular support (38) defining an inlet tube (45) and a closed forward end positioned within the outlet tube. Lateral aperture means (46) are provided in the tubular support, and an elastic tube (40) surrounds the inner tubular support to cover the lateral apertures. The inner tubular support is free of elastic, tube-retaining structures at its closed end, and is adapted to permit the elastic tube to be laterally slidable on the inner, tubular support through a limited distance. The outer housing defines vanes (44) to limit the lateral advancement of the elastic tube on the support, while shoulder means (42) are positioned about the support to limit the lateral retraction of the elastic tube away from the closed end.
    Type: Grant
    Filed: September 9, 1980
    Date of Patent: August 31, 1982
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventor: Lee K. Kulle
  • Patent number: 4344429
    Abstract: In a flow metering apparatus, a bubble detector for detecting bubble formation in tubing includes a light source and first and second light detectors. The first light detector is positioned on the opposite side of the tubing from the light source such that the light transmitted through the tubing to the detector is dependent on the focusing effect of fluid in the lumen of the tubing. A control circuit responsive to the output of the detector interrupts operation of the metering apparatus when the light transmitted through the tubing falls below a predetermined minimum level. The second light detector is positioned at an angle to the light path between the light source and the first detector so as to receive increased light from the light source in the absence of the focusing effect of fluid in the tubing.
    Type: Grant
    Filed: December 13, 1979
    Date of Patent: August 17, 1982
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: John E. Gupton, Norman Shim
  • Patent number: 4337769
    Abstract: A liquid administration device comprises a flexible, collapsible bag for the liquid, an outlet tube communicating with the bag and a rigid housing enclosing the bag with the outlet tube projecting outwardly therefrom. Flexible, compressed cellular material is positioned within the housing, exerting pressure due to its compression on the bag which tends to urge the bag towards its collapsed position. Thus the liquid in the bag can be expelled through the outlet tube, with the flow governed by a valve, in a manner independent of gravity.
    Type: Grant
    Filed: August 1, 1980
    Date of Patent: July 6, 1982
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventor: Raymond G. Olson
  • Patent number: 4336802
    Abstract: A flexible, flat-collapsible bag containing parenteral solution may be adapted for aseptically receiving and mixing the contents of another container, with the flat-collapsible bag preferably initially containing, prior to receiving said contents, a liquid for parenteral administration in a volume of 30 to 70 percent of the holding capacity of said flat-collapsible bag. The bag defines at least a pair of access ports, one of the ports being sealingly connected to flexible, crimpable, thermoplastic tubing of a length of at least 11/2 inches, and a sealed connector member carried on the outer end of the flexible thermoplastic tubing, in which the seal connector member defines a sleeve including a sealing diaphragm in the bore thereof, with the sleeve constituting an extension of the flexible thermoplastic tubing. Accordingly, a piercing spike may sealingly enter the sleeve to rupture the diaphragm.
    Type: Grant
    Filed: July 28, 1980
    Date of Patent: June 29, 1982
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: Albert J. Stone, Michael D. Nissen
  • Patent number: 4335770
    Abstract: An enteral feeding container having a relatively enlarged port and closure which is resistant to popping open upon dropping. The enteral container may have a tapered portion for improved accuracy of administration.
    Type: Grant
    Filed: October 8, 1980
    Date of Patent: June 22, 1982
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: Lee K. Kulle, Kenneth W. Larson
  • Patent number: D266190
    Type: Grant
    Filed: June 13, 1980
    Date of Patent: September 14, 1982
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventor: Yves Herman
  • Patent number: RE31082
    Abstract: A thermoplastic pharmaceutical solution container includes a neck portion having at least one port through the neck portion. A thermoplastic port protector or closure covers the port and defines a frangible section. The closure has a length to diameter ratio providing good mechanical advantage leverage to rupture the frangible section when the closure is pushed sideways.
    Type: Grant
    Filed: February 7, 1979
    Date of Patent: November 16, 1982
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventor: David A. Winchell
  • Patent number: D267270
    Type: Grant
    Filed: November 15, 1979
    Date of Patent: December 14, 1982
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventor: Herbert Mittleman
  • Patent number: RE31135
    Abstract: The method of molding flexible, collapsible containers comprises extruding a tubular parison of material to be molded and sealing the outer, free end of the parison; ballooning the parison with relatively low pneumatic pressure; closing the mold about the ballooned parison to cause the edges of the parison to protrude out of the mold chamber; and sealing said parison to form said container, including the step of forming seal lines positioned laterally inwardly from the lateral edges of the parison. A novel container design is also covered.
    Type: Grant
    Filed: March 3, 1982
    Date of Patent: February 1, 1983
    Assignee: Baxter Travenol Laboratories, Inc.
    Inventors: David A. Winchell, Jerry D. Martin, Frank L. Roe