Patents Represented by Attorney, Agent or Law Firm Joshua B. Goldberg
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Patent number: 7414068Abstract: The present invention relates to benzopyran derivatives substituted with secondary amines including tetrazole, method for preparing thereof and pharmaceutical compositions containing them. The compounds of the present invention can be used for protecting neuronal cells and brain damage; antioxidation; inhibiting NO generation; protecting heart; suppressing angiogenesis; protecting preserving organs such as kidney, heart and tissue, and protecting organs in major cardiovascular surgery.Type: GrantFiled: April 10, 2003Date of Patent: August 19, 2008Assignee: Dongbu Hannong Chemical Co., Ltd.Inventors: Hong Lim, Dong-Ha Lee, Sun-Ok Kim, In-Young Choi, Sung-Eun Yoo, Kyu-Yang Yi, Sun-Kyung Lee, Jee-Hee Suh, Nak-Jeong Kim, Byung-Ho Lee, Ho-Won Seo, Hwa-Sup Shin
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Patent number: 7312282Abstract: Processes for preparing block copolymers and the block copolymers prepared therefrom comprising at least two types of homoblock, all belonging to the polysulfone family, wherein each of the said homoblocks has an identical or different molecular weight of at least 1000 and comprises at least 5% of the overall weight of the block copolymer, and wherein the block copolymer has a molecular weight of at least 2000, the process steps comprising preparing each of the aforesaid homoblocks by reacting at least one aromatic diol with at least one aromatic dihalo compound, one of which contains at least one sulfone group, in at least one aprotic solvent in the presence of at least one alkali, optionally in the presence of an azeotropic agent and then reacting the aforesaid homoblocks together in at least an aprotic solvent, optionally followed by end-capping said block copolymer.Type: GrantFiled: July 23, 2004Date of Patent: December 25, 2007Inventors: Prakash Druman Trivedi, Atulkumar Ramaniklal Raja, Mukesh Shambhubhai Jesani
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Patent number: 6831077Abstract: The present invention relates to pharmaceutical compositions comprising an atypical antipsychotic agent in combination with a chromium salt, which are used for treating atypical depression, as well as minimizing side effects in a patient taking an atypical antipsychotic agent.Type: GrantFiled: July 25, 2002Date of Patent: December 14, 2004Assignee: Comprehensive Neuroscience, Inc.Inventor: John Docherty
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Patent number: 6815572Abstract: The present invention provides a method of processing organic waste (D) in divided solid and/or liquid form, the method being implemented in a single reactor (1) containing a bath of molten glass (V) surmounted by a gas phase (G), the method comprising incinerating said waste (D) in the presence of oxygen at the surface (S) of said bath of molten glass (V), and in vitrifying said incinerated waste (D) in said bath of molten glass (V). In said method, and in characteristic manner, in addition to the oxygen delivered as oxidizer into said gas phase (G), oxygen is also injected into said bath of molten glass (V) in a quantity that is sufficient to minimize or to avoid any formation of metal within said bath of glass (V); advantageously in a quantity that is sufficient to minimize or to avoid any formation of metal within said bath of glass (V) and also to subject said bath of glass (V) to moderate stirring.Type: GrantFiled: May 24, 2001Date of Patent: November 9, 2004Assignees: Korea Electric Power Corporation, Societe General pour les Techniques Nouvelles - SGNInventors: Pierre Brunelot, Jacques Lacombe, Serge Merlin, Patrice Roux, Valérie Thiebaut, Kwan-Sik Choi, Myung-Jae Song
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Patent number: 6803050Abstract: The invention relates to optically transparent aqueous compositions containing hydrophobic silicone oil and a comparably low amount of wash-active matter, being suitable as a hair treatment composition such as a shampoo. In particular, it provides an optically transparent aqueous composition comprising (a) a hydrophobic silicone oil in an amount of 1-3 wt.-% with respect to the total weight of the composition; (b) a solubilizer for the silicone oil; and (d) an anionic surfactant; wherein the weight-ratio of component (b) to component (a) is in the range of 1:1 to 12:1; and wherein the total amount of the components (b) and (c) is in the range of 10-25 wt.-% with respect to the total weight of the composition. The invention also provides a method for preparing the above composition.Type: GrantFiled: July 9, 2003Date of Patent: October 12, 2004Assignee: Kao Chemicals Europe S.L.Inventors: Horst Denzer, Hiroshi Abe, Monika Pytlik, Rosemarie Jansen, Andrea Buhmann
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Patent number: 6793874Abstract: A cooling system for a blast furnace includes a cooling circuit (10) closed by a return line (16) and at least one circulation pump (26, 26′, 26″) for circulating cooling water through the closed cooling circuit. An emergency feed line (36) with an emergency feed valve (38), which opens in case of a power failure, is connected to the cooling circuit (10). An emergency overflow valve (68) is located at the highest point of the closed cooling circuit (10). This emergency overflow valve (68) opens in case of a power failure, so that the closed cooling circuit (10) becomes an open cooling circuit (10) with an atmospheric pressure discharge at its highest point. A pressure vessel (34), which is connected to the emergency feed line (36), contains a certain volume of emergency water which is pressurised by a gas, so that, in case of a power failure, an emergency water flow establishes through the open cooling circuit (10).Type: GrantFiled: October 22, 2002Date of Patent: September 21, 2004Assignee: Paul Wurth S.A.Inventors: Giang Kien Ly, Robert Schmeler
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Patent number: 6750005Abstract: Disclosed are a spectrofluorimetrically detectable luminescent composition and processes for enhancing the luminescence of one or more lanthanide-containing macrocycles. The luminescent composition comprises a micelle-producing amount of at least one surfactant, at least one energy transfer acceptor lanthanide element macrocycle compound having an emission spectrum peak in the range from 500 to 950 nanometers, and a luminescence-enhancing amount of at least one energy transfer donor compound of yttrium or a 3-valent lanthanide element having atomic number 59-71, provided that the lanthanide element of said macrocycle compound and the lanthanide element of said energy transfer donor compound are not identical. The addition of gadolinium(III) in the presence of other solutes to both the prototype and the di-functionalized europium, samarium, and terbium macrocyclic complexes, which were taught in our U.S. Pat. Nos. 5,373,093 and 5,696,240, enhances their luminescence.Type: GrantFiled: December 6, 2001Date of Patent: June 15, 2004Inventors: Robert C. Leif, Lidia Vallarino
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Patent number: 6740639Abstract: The invention provides novel inclusion complexes of highly potent opioid peptide of L-Tyrosyl-D-alanyl-glycyl-N-methylphenylalanyl-glycyl-isopropylamide with cyclodextrin, pharmaceutical preparations containing these inclusion complexes of L-Tyrosyl-D-alanyl-glycyl-N-methylphenylalanyl-glycyl-isopropylamide with cyclodextrin derivatives, the complexes being better soluble in water and having improved biopharmaceutical properties such as lesser toxicity, better analgesic action and non-addiction properties.Type: GrantFiled: March 29, 2000Date of Patent: May 25, 2004Assignee: Council of Scientific & Industrial ResearchInventors: Anil Kumar Dwivedi, Madhu Khanna, Wahajul Haq, Ram Raghubir, Sudhir Srivastava, Puvvada Sri Ramchandra Murthy, Onkar Prasad Asthana, Jagdishwar Sahay Srivastava, Satyawan Singh
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Patent number: 6720068Abstract: The invention relates to a sound absorbent thin-layer laminate consisting of at least one open-cell support layer and a second open-cell fibre layer. The support layer consists either of a first fibre layer, especially a low-density non-woven material with a mass per unit area of less than 2,000 g/m2 and a thickness of less than 50 mm, or of an open-cell foam layer, especially an ultra-light plastic foam with a density of between 16 and 32 kg/m3 and a thickness of at least 6 mm. The second fibre layer is made of melt-blown microfibres, whose fibre diameter is approximately 1 to 10 &mgr;m, especially 2 to 5 &mgr;m. The air resistance of the thin-layer laminate is in the range of 500<Rt<4,000 Ns/m3. According to the method for producing the thin-layer laminate a microfibre layer of melt-blown microfibres with a diameter of between 1 and 10 &mgr;m, preferably between 2 and 5 &mgr;m, is fixed to the support layer by means of a spray-on adhesive.Type: GrantFiled: May 27, 2003Date of Patent: April 13, 2004Assignee: Rieter Automotive (International) AGInventors: William Ray Vanbemmel, Anthony C. Vulpitta, Thorsten Alts
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Patent number: 6663701Abstract: An emulsion ink for stencil printing comprises 20 to 50 wt. % of an oil phase and 50 to 80 wt. % of a water phase, and contains at least one kind of a vegetable oil with an iodine number ranging from 110 to 150 in the oil phase at least in an amount indicated by the following formula in wt. %, and an antioxidant in an amount ranging from 1 to 10 wt. % based on the content of the vegetable oil: Minimum amount of vegetable oil in wt. %=amount of water in ink in wt. %×(100/iodine number)×0.09. The ink causes no clogging or offset when a printer is not in operation and the ink is left in a printing drum of the printer for a long period of time. Disclosed is also a printed matter printed by the emulsion ink of the present invention.Type: GrantFiled: January 11, 2002Date of Patent: December 16, 2003Assignee: Riso Kagaku CorporationInventors: Hiroyuki Ogawa, Hideaki Takayama
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Patent number: 6661510Abstract: A device for detection of one or several fluorescent species, said species being contained in a medium, said medium being contained in a conduit, said device comprising a means of exciting the fluorescent species by light, said medium and conduit making up a structure that is transparent to the exciting and the emitted fluorescent light, and said device comprising one or several such structures, may be improved by letting at least part of the emitted fluorescent light be guided away from the illumination zone by total internal reflection (TIR) in said structure and collected from one end of said structure.Type: GrantFiled: January 11, 2001Date of Patent: December 9, 2003Assignees: Hanning Instruments AB, R&B Scientific ABInventors: Anders Hanning, Johan Roeraade
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Patent number: 6635287Abstract: A dormant preparation (DC) is provided which is capable of inhibiting proliferation of various kinds of cells. The preparation comprises an extract which is obtained from cells or tissue originating in an organism capable of entering a phase of dormancy in at least one of its parts and comprises at least one substance which induces or maintains the state of dormancy in the organism from which the cells or tissue are derived. The DC may be used for a variety of indications including human medicine and cosmetics, plant growth control and food preservation.Type: GrantFiled: July 27, 2001Date of Patent: October 21, 2003Assignee: I.B.R. Israeli Biotechnology Research Ltd.Inventors: Etienne Soudant, Lea Bezalel, Meira Ziv, Inon Perry
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Patent number: 6630483Abstract: N-oxides of the compounds of formula (I) in which R1 is hydroxyl, 1-4C-alkoxy, 3-7C-cycloalkoxy, 3-7C-cycloalkylmethoxy or completely or predominantly fluorine-substituted 1-4C-alkoxy, R2 is hydroxyl, 1-4C-alkoxy, 3-7C-cycloalkoxy, 3-7C-cycloalkylmethoxy or completely or predominantly fluorine-substituted 1-4C-alkoxy, or in which R1 and R2 together are a 1-2C-alkylenedioxy group, R6 is an R7- and R8-substituted phenyl radical, they are active bronchial therapeutics.Type: GrantFiled: June 18, 2002Date of Patent: October 7, 2003Assignee: Altana Pharma AGInventor: Beate Schmidt
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Patent number: 6627083Abstract: Sintered light expanded clay aggregates are described that are prepared by expanding and firing a clay-based material, and where the finished aggregates have a diameter of up to about 32 mm, for use as filtration medium for purifying water, wherein carbonates of calcium and/or magnesium are added to the clay as flux material prior to expansion and firing. Uses of the expanded clay aggregates for removing phosphorous by utilising die clay aggregates are also described, as well as a method for removing phosphorus by using the clay aggregates.Type: GrantFiled: February 21, 2001Date of Patent: September 30, 2003Assignee: A.S. Norsk LecaInventors: Roy Rennesund, Petter Deinboll Jenssen, Tore Krogstad
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Patent number: 6628123Abstract: A method for controlling a transducer device (7) featuring supply lines (17, 18) in a level sensor. The transducer device (7) is coupled to a fork resonator with fork tines and is used for both oscillation excitation and also for oscillation detection. For detection of a defective transducer device or an incorrectly connected connection of this transducer device (7), the capacitance value between the supply lines (17,18) or a variable proportional to this value is determined during the oscillation excitation and if there is deviation from a predetermined desired value by a predetermined amount, a fault signal is generated.Type: GrantFiled: February 20, 2001Date of Patent: September 30, 2003Assignee: VEGA Grieshaber KGInventors: Felix Raffalt, Adrian Frick
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Patent number: 6624181Abstract: The invention relates to the combined administration of PDE inhibitors and &bgr;2 adrenoceptor agonists for the treatment of respiratory tract disorders.Type: GrantFiled: February 20, 2002Date of Patent: September 23, 2003Assignee: Altana Pharma AGInventors: Ulrich Kilian, Christian Schudt
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Patent number: 6610249Abstract: A composition for disinfecting an animal product comprising an electro-chemically activated, anion-containing aqueous solution. A plant for treating an animal product including a water reservoir (12), a salt feed device (16) for creating an aqueous salt solution, an electrolysis device (18) to produce anolyte and catolyte solutions, an anion mixing tank (28), and a treatment container (30) to apply the solution to an animal product.Type: GrantFiled: June 19, 2000Date of Patent: August 26, 2003Assignee: Radical Waters IP (PTY) LTDInventor: Gilbert Theo Hinze
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Patent number: 6596319Abstract: The present invention relates to a composition for use as an immunomodulator comprising small molecular weight components of less than 3000 daltons, and having the following properties: a) is extractable from bile of animals; b) is capable of stimulating monocytes and macrophages in vitro and in vivo; c) is capable of modulating tumor necrosis factor production; d) contains no measurable IL-1&agr;, IL-1&bgr;, TNF, IL-6, IL-8, IL-4, GM-CSF or IFN-&ggr;; e) has an anti-proliferative effect in a malignant mouse hybridoma cell line; f) shows no cytotoxicity to human peripheral blood mononuclear cells or lymphocytes; and g) is not an endotoxin. The invention also relates to a method of preparing the composition, its use as an immunomodulator, and its use in the treatment of diseases and conditions having an immunological component.Type: GrantFiled: January 17, 2001Date of Patent: July 22, 2003Assignee: Lorus Therapeutics Inc.Inventors: Romeo G. Rang, Paul B. Percheson
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Patent number: 6589567Abstract: This invention is about the identification of the HD-2, a natural chemical substance that was separated and purified from a natural product, Sinsuk, as arsenic hexoxide (As4O6) and about its therapeutic efficacy as an anti-cancer drug and pharmaceutical composition. Arsenic hexoxide (As4O6), a natural chemical substance obtained from Sinsuk after eliminating the toxic property, has a potent anti-cancer efficacy by its direct cytotoxicity on tumor cells and suppresses the formation of new blood vessels of tumor masses, which results in complete cure of malignant cancers.Type: GrantFiled: September 14, 2001Date of Patent: July 8, 2003Inventors: Ill-Ju Bae, Jong-Bae Kim, Choong-Ki Eun, Seung-Kyu Song, Byung-Sun Suh, Kwan-Hee Lee, Myoung-Sool Doo, Jin-Hwan Kwak, Byung-Doo Song, Taek-Joon Yoon, Tae-Bong Kang, Choon-Ho Park
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Patent number: RE38153Abstract: A two dimensional beam deflector is disclosed which deflects beams from multiple optical assemblies. The input of beams of the multiple optical assemblies follow parallel optical paths until deflection to a wafer. An ellipsometer using a two-dimensional beam deflector is also disclosed.Type: GrantFiled: April 24, 2000Date of Patent: June 24, 2003Assignee: Nova Measuring Instruments, Ltd.Inventor: Moshe Finarov